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Acta Mathematica Sinica,English Series 2024年第9期40卷 2091-2152页

作者： Qi An GUAN zhi tong mi Zheng YUAN School of Mathematical Sciences Peking UniversityBeijing 100871P.R.China School of Mathematics and Statistics Beijing Jiaotong UniversityBeijing 100044P.R.China Institute of Mathematics Academy of Mathematics and Systems ScienceChinese Academy of SciencesBeijing 100190P.R.China

In this article,we consider a modified version of minimal L^(2) integrals on sublevel sets of plurisubharmonic functions related to modules at boundary points,and obtain a concavity property of the modified *** applications,we give characterizations for the concavity degenerating to linearity on open Riemann surfaces and on fibrations over open Riemann surfaces.

关键词： minimal L^(2)integrals plurisubharmonic functions boundary points weakly pseudoconvex Kähler manifold

基于UFAC应力吸收层的抗反射裂缝性能评价

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河南理工大学学报（自然科学版） 2025年第1期44卷 185-192页

作者：李智童竞华南理工大学土木与交通学院广东广州510641

目的为了解决“白加黑”技术中的反射裂缝问题,针对目前常用的悬浮密实型高弹改性沥青混合料(super flexible asphalt concrete,SFAC)应力吸收层变形量较大、容易造成上部沥青加铺层不利于受力的缺陷,方法提出基于CAVF法和富沥青理念优... 详细信息

目的为了解决“白加黑”技术中的反射裂缝问题,针对目前常用的悬浮密实型高弹改性沥青混合料(super flexible asphalt concrete,SFAC)应力吸收层变形量较大、容易造成上部沥青加铺层不利于受力的缺陷,方法提出基于CAVF法和富沥青理念优化设计的骨架密实型UFAC应力吸收层。采用有限元ABAQUS数值模拟方法对“白加黑”路面结构进行受力分析,并通过加速加载试验、冲击韧性试验和劈裂试验对材料与结构的抗反射裂缝性能进行评价。结果重载条件下,UFAC应力吸收层和高弹改性沥青应力吸收层的竖向位移相差5.93×10^(-2)mm,沥青加铺层底部所受竖向压应力σy、最大主应力σ_(max)、最大剪应力τ_(12)分别降低24%,32.3%,27.7%。当路面存在严重脱空或常规脱空情况时,基于UFAC应力吸收层的路面结构比GAC加铺路面结构的抗疲劳开裂性能分别提升48%,36%。与传统的悬浮型砂粒式AC-5应力吸收层相比,UFAC-5应力吸收层的冲击韧性增加60.8%,劈裂抗拉强度提高16.8%。结论基于UFAC应力吸收层的沥青加铺技术,通过增大常规改性沥青膜厚保证必要的疲劳抗拉能力,并采用骨架密实型级配显著提高集料间的嵌挤能力和内摩阻力,减小层间结构变形,可有效减缓沥青加铺层反射裂缝的产生与发展。

关键词：应力吸收层薄层富沥青混合料骨架密实型有限元数值模型抗压变形

追寻东坡足迹,倾听苏子心声--《念奴娇·赤壁怀古》《赤壁赋》联读教学探索

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黄冈师范学院学报 2025年第1期45卷 52-57页

作者：童志国安徽省铜陵市第十八中学安徽铜陵244121

《念奴娇·赤壁怀古》与《赤壁赋》作为苏轼在豪放词和赋体散文领域的代表作,其在高中语文教学中的价值不容忽视。本研究采用比较式群文联读模式,对这两篇体裁各异但题材与创作背景相似的经典文学作品进行比较阅读教学。经过“感知性阅... 详细信息

《念奴娇·赤壁怀古》与《赤壁赋》作为苏轼在豪放词和赋体散文领域的代表作,其在高中语文教学中的价值不容忽视。本研究采用比较式群文联读模式,对这两篇体裁各异但题材与创作背景相似的经典文学作品进行比较阅读教学。经过“感知性阅读—读出情感”“理解性阅读—读出作者”“思辨性阅读—读出发现”三个阶段的系列教学活动,旨在深度剖析苏轼作品中蕴含的深层心理意涵,解读苏子字里行间隐藏的心灵密码,从而实现对经典文本的持续创新解读与教学,达到使经典作品常读常新、教学方法常教常新的目标。

关键词：《念奴娇·赤壁怀古》《赤壁赋》感知性阅读理解性阅读思辨性阅读高阶思维

Deciphering fungal metabolon coupling tandem inverse-electrondemand Diels-Alder reaction and semipinacol rearrangement for the biosynthesis of spiro polycyclic alkaloids

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Science China Chemistry 2025年第01期 288-296页

作者： Shuai Liu Wen-Qiang Xu Ying-tong Di Man-Cheng Tang Ding-Kang Chen ming-ming Cao Yao-Wen Chang Hong-Yu Tang Chun-Mao Yuan Jun-Bo Yang zhi-Li Zuo Han Guo Zi-Fei Xu Ying Zeng Yun-Dong Wu Xiao-Jiang Hao Key Laboratory of Phytochemistry and Natural Medicines (Chinese Academy of Sciences) Kunming Institute of Botany Chinese Academy of Sciences University of Chinese Academy of Sciences Lab of Computational Chemistry and Drug Design State Key Laboratory of Chemical Oncogenomics Peking University Shenzhen Graduate School Shenzhen Bay Laboratory State Key Laboratory of microbial Metabolism School of Life Sciences & Biotechnology Shanghai Jiao Tong University State Key Laboratory of Functions and Applications of Medicinal Plants Guizhou Medical University Molecular Biology Experimental Center Germplasm Bank of Wild Species in Southwest China Kunming Institute of Botany Chinese Academy of Sciences Yunnan Key Laboratory for Wild Plant Resources Kunming Institute of Botany Chinese Academy of Sciences Research Unit of Chemical Biology of Natural Anti-Virus Products Chinese Academy of Medical Sciences

In the intricate process of natural product biosynthesis, a metabolon can enhance metabolic flux by associating sequential enzymes. A fungal metabolon, comprising of flavin-dependent monooxygenase Spe F and P450 monooxygenase Spe G, is identified in the biosynthesis of spiro polycyclic alkaloids(+)-notoamide B and its diastereomer(+)-versicolamide B. Using notoamide E as a substance, Spe F/Spe G metabolon can control the stereoselectivity of its 2,3-epoxidation, followed by hydrogen atom ion at C-17 to generate reactive epoxide tau-m A with dienyl iminium unit. Subsequently,(+)-notoamide B and(+)-versicolamide B are produced via tandem nonenzymatic inverse-electron-demand Diels-Alder reaction and semipinacol rearrangement. This provides the first example of metabolon in the biosynthesis of spiro-prenylated indole alkaloids.

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Insights into spinal muscular atrophy from molecular biomarkers

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Neural Regeneration Research 2025年第7期20卷 1849-1863页

作者： Xiaodong Xing Xinzhu Liu Xiandeng Li mi Li Xian Wu Xiaohui Huang Ajing Xu Yan Liu Jian Zhang Department of Clinical Pharmacy Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghaiChina College of Pharmacy Chongqing Medical UniversityChongqingChina

Spinal muscular atrophy is a devastating motor neuron disease characterized by severe cases of fatal muscle *** is one of the most common genetic causes of mortality among infants aged less than 2 *** research is currently receiving more attention,and new candidate biomarkers are constantly being *** review initially discusses the evaluation methods commonly used in clinical practice while briefly outlining their respective pros and *** also describe recent advancements in research and the clinical significance of molecular biomarkers for spinal muscular atrophy,which are classified as either specific or non-specific *** review provides new insights into the pathogenesis of spinal muscular atrophy,the mechanism of biomarkers in response to drug-modified therapies,the selection of biomarker candidates,and would promote the development of future ***,the successful utilization of biomarkers may facilitate the implementation of gene-targeting treatments for patients with spinal muscular atrophy.

关键词： biomarkers disease progression gene-targeting therapy neurofilaments Nusinersen spinal muscular atrophy(SMA) survival motor neuron therapeutic evaluation treatment outcomes

Single neuron network PI control of high reliability linear induction motor for Maglev

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第3期8卷 408-411页

作者： FANG You-tong FAN Cheng-zhi College of Electrical Engineering Zhejiang University Hangzhou 310027 China

The paper deals with a new model of linear induction motor (LIM) to improve the reliability of the system. Based on the normal equation circuit of LIM considering the dynamic end effect, an equivalent circuit model with compensation of large end effect is constructed when the end effect force at synchronism is of braking character. The equivalent circuit model is used for secondary-flux oriented control of LIM. Single neuron network PI unit for LIM servo-drive is also discussed. The effectiveness of mathematical model for drive control is verified by simulations.

关键词： Linear induction motor (LIM) Field-oriented control End effect

Design and Implementation of the Tianhe-2 Data Storage and Management System

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Journal of Computer Science & Technology 2020年第1期35卷 27-46页

作者： Yu-tong Lu Peng Cheng zhi-Guang Chen National Supercomputer Center in Guangzhou Sun Yat-sen UniversityGuangzhou 510000China College of Computer National University of Defense TechnologyChangsha 410073China

With the convergence of high-performance computing(HPC),big data and artificial intelligence(AI),the HPC community is pushing for"triple use"systems to expedite scientific ***,supporting these converged applications on HPC systems presents formidable challenges in terms of storage and data management due to the explosive growth of scientific data and the fundamental differences in I/O characteristics among HPC,big data and AI *** this paper,we discuss the driving force behind the converging trend,highlight three data management challenges,and summarize our efforts in addressing these data management challenges on a typical HPC system at the parallel file system,data management middleware,and user application *** HPC systems are approaching the border of exascale computing,this paper sheds light on how to enable application-driven data management as a preliminary step toward the deep convergence of exascale computing ecosystems,big data,and AI.

关键词： high-performance computing(HPC) data management converged application parallel file system

microRNA21 Meets Neuronal TLR8: Non-canonical Functions of microRNA in Neuropathic Pain

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Neuroscience Bulletin 2019年第5期35卷 949-952页

作者： zhi-Hong Wang tong Liu Jiangsu Key Laboratory of Neuropsychiatric Diseases and Institute of Neuroscience Soochow University Suzhou 215021 China College of Life Sciences Yanan University Yanan 716000 China

Toll-like receptors (TLRs) are well-known as patternrecognition receptors in the immune system for recognizing pathogen-associated and damage-associated molecular patterns [1]. TLRs play an essential role in the innate and adaptive immune responses. To date, 10 functional TLRs have been identified in humans (TLR1–TLR10) and 12 in mice (TLR1–TLR9 and TLR11–TLR13)[1]. TLRs are evolutionarily conserved type I transmembrane proteins and comprise an ectodomain characterized by leucine-rich repeats mediating the recognition of ligands, a transmembrane region, and cytosolic Toll-interleukin (IL)-1 receptor domains that activate the downstream signaling pathways [1].

关键词： microRNA21 Neuronal TLR8 Neuropathic Pain

Recent advances in 2D semiconductor nanomaterials for photocatalytic CO_(2)reduction

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Nano Research 2023年第7期16卷 8542-8569页

作者： tong Li Hongwei Huang Shuobo Wang Yan mi Yihe Zhang Beijing Key Laboratory of Materials Utilization of Nonmetallic minerals and Solid Wastes National Laboratory of Mineral MaterialsSchool of Materials Science and TechnologyChina University of Geosciences(Beijing)Beijing 100083China Goods and Material Department of CASIC Tertiary Research Institute China Aerospace Science and Industrial CorporationBeijing 100074China Key Laboratory of Chemistry and Engineering of Forest Products State Ethnic Affairs CommissionGuangxi Key Laboratory of Chemistry and Engineering of Forest ProductsGuangxi Collaborative Innovation Center for Chemistry and Engineering of Forest ProductsGuangxi Minzu UniversityNanning 530006China

For decades,global warming and energy shortages have been two urgent problems in human *** solar-driven photocatalytic conversion of carbon dioxide(CO_(2))into hydrocarbon fuels is expected to become a technology to solve these ***-dimensional(2D)materials shine in the field of photocatalytic CO_(2)due to their layered structure,larger specific surface area,more active sites,and larger charge transfer *** article reviews the progress of CO_(2)reduction by several types of 2D materials in recent ***,the reduction of CO_(2)is difficult in terms of kinetics and thermodynamics,but it is found through theoretical calculations and experiments that 2D materials have certain advantages in the reduction of CO_(2).Then the preparation methods of 2D materials are summarized and a variety of 2D materials are discussed and ***,an outlook on the development trend of 2D materials is *** review aims to provide systematic and concise guidance for the design of 2D nanomaterials for photocatalytic CO_(2)reduction.

关键词： two-dimensional(2D)materials photocatalysis CO_(2)reduction charge separation reactive sites

Numerical study on lateral wall displacement of deep excavation supported by IPS earth retention system

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Underground Space 2017年第4期2卷 259-271页

作者： Tugen Feng Long Liu Tao tong mi Zhou Key Laboratory of M inistry of Education for Geomechanics and Embankment Engineering Jiangsu Research Center for Geotechnical Engineering TechnologyHohai University1 Xikang RdNanjing 210098China Survey and Design Research Institute of Jiangxi Province 169 Zhiyang RdNanchang 330095China School of Civil and Transportation Engineering State Key labor atory of Subtropical Building ScienceSouth China University of Techmnology381 Wushan RoadGuangzhou 510640China

The objective of this study is to investigate the 3D behavior characteristics of an excavation supported by an innovative prestressed support(IPS)earth retention system.A numerical simulation was conducted in order to provide insight into the IPS system behavior by using the FLAC3D *** to the parametric study,validation work was conducted by means of a comparison of the deformation between theﬁeld test data and numerical analysis results,and strong agreement was *** reasonable excavation location,lay-ered excavation thickness,and blocked excavation sequence are presented according to variable parameter *** view of the pre-viousﬁndings,certain measurements are proposed in order to control the foundation pit *** results indicate that prestress compensation has a signiﬁcant effect on the IPS system behavior,while an optimized excavation sequence slightly improves its *** the conclusion proposed based on the numerical results,the aim is to provide reference data for optimization design and the construction sequence.

关键词： FLAC3D IPS system Prestress compensation Layered excavation Blocked excavation Deformation control