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MicroRNAs and long non-coding RNAs in liver surgery:Diagnostic and therapeutic merits

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Hepatobiliary & Pancreatic Diseases International 2020年第3期19卷 218-228页

作者： zhi-qiu Hu Yi Lu Di Cui Chen-Yang Ma Su Shao Ping Chen Ran Tao Jian-Jun Wang Department of Surgery Minhang HospitalFudan UniversityShanghai 201199China Department of Hepatobiliary-Pancreatic&Minimally Invasive Surgery Affiliated Zhejiang Provincial People’s HospitalHangzhou Medical SchoolHangzhou 310014China Center for Clinical Medical Research Affiliated Zhejiang Provincial People’s HospitalHangzhou Medical SchoolHangzhou 310014China Department of General Surgery Chun’an 1st People’s HospitalHangzhou 311700China Department of Obstetrics and Gynecology Shaoxing 2nd HospitalShaoxing 312000China

Background:Hepatectomy and liver transplantation(LT)are the two most commonly performed surgical procedures for various hepatic *** RNA(mi RNA)and long non-coding RNA(lnc RNA)have been gradually unveiled their roles as either biomarkers for early diagnosis or potentially therapeutic tools to manipulate gene expression in many disease *** review aimed to discuss the effects of mi RNA or lnc RNA in the hepatectomy and LT *** sources:We did a literature search from 1990 through January 2018 to summarize the currently available evidence with respect to the effects of mi RNA and lnc RNA in liver regeneration after partial hepatectomy,as well as their involvement in several key issues related to LT,including ischemia-reperfusion injury,allograft rejection,tolerance,recurrence of original hepatic malignancies,***:Certain mi RNAs and lnc RNAs are actively involved in the regulation of various aspects of liver resection and *** the process of liver regeneration after hepatectomy,the expression of mi RNAs and lnc RNAs shows dynamic ***:It is now clear that mi RNAs and lnc RNAs orchestrate in various aspects of the pathophysiological process of LT and *** understanding of the underlying mechanism and future clinical trials may strengthen their positions as either biomarkers or potential therapeutic targets in the management of complications after liver surgery.

关键词： Hepatectomy Liver transplantation microRNA Long non-coding RNA Ischemia-reperfusion injury Rejection

Architecture of stem and branch affects yield formation in short season cotton

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Journal of Integrative Agriculture 2020年第3期19卷 680-689页

作者： ZHANG Xiang RUI qiu-zhi LI Yuan CHEN Yuan CHEN Yuan ZHANG Xi-ling CHEN De-hua SONG Mei-zhen Institute of Cotton Research Chinese Academy of Agricultural Sciences/State Key Laboratory of Cotton BiologyAnyang 455000P.R.China Jiangsu Key Laboratory of Crop Genetics and Physiology/Co-Innovation Center for Modern Production Technology of Grain Crops Yangzhou UniversityYangzhou 225009P.R.China

The cotton direct seeding after wheat(rape) harvested is under trial and would be the future direction at the Yangtze River Valley region of *** objective of this study was to quantify the effects of branch and stem architecture on cotton yield and identify the optimal cotton architecture to compensate the yield loss due to the reduction of individual production capacity under high planting density in the direst seeding after wheat harvested cropping *** characteristics of the stem and branch architecture and the relationships between architecture of the stem and branch with yield formation were studied on eight short season cotton cultivars during 2015 and 2016 cotton growth *** on the two years results,three cultivars with different architectures of stem and branch were selected to investigate the effect of mepiquat chloride(MC) application on the architecture of the stem and branch,boll retention,and the yield in *** differences were observed on plant height,all fruiting nodes to branches ratio(NBR) in the cotton plant,and the curvature of the fruiting branch(CFB) among the studied *** were three types of stem and fruiting branch structures: Zhong425 with stable and suitable plant height and NBR(about 90 cm and 2.5,respectively),high CFB(more than 10.0),and high boll retention speed and seed cotton yield;Siyang 822 with excessive plant height and NBR,low CFB,and low boll retention speed and seed cotton yield;and other studied cultivars with unstable structure of stem and branch,boll retention speed,and seed cotton yield across *** MC application could promote the appropriate plant height and NBR and high CFB and thus resulted in high boll retention speed and the *** results suggested that the suitable plant height and NBR(about 90 cm and 2.5 respectively),and high CFB(more than 10.0),which was related to both genotype and cultural practice,could promote the higher boll retention speed and seed cotton yie

关键词： short season cotton architecture of the stem and branch boll retention speed seed cotton yield mepiquat chloride

Clinical evaluations of mineralized collagen in the extraction sites preservation

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Regenerative Biomaterials 2016年第1期3卷 41-48页

作者： Lu Feng Liang Zhang Yun Cui Tian-Xi Song zhi-Ye qiu Xiu-Mei Wang Bao-Sheng Tan Department of Stomatology Dongzhimen HospitalBeijing University of Chinese MedicineBeijing 100700China Beijing Stomatological Hospital Capital Medical UniversityBeijing 100050China Second Outpatient Department General Hospital of Beijing Military RegionBeijing 100125China Beijing Allgens Medical Science and Technology Co. Ltd.Beijing 100176China State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing 100084China

The purpose of this study was to explore the different effects between biomimetic mineralized collagen(MC)and ordinary physically blended hydroxyapatite/collagen(HA/Col)composite in evaluating new bone formation and regenerated bone height in human extraction ***-four patients who cannot retain teeth caused by trauma or decay were randomly selected from Department of Stomatology of Dongzhimen Hospital from December 2013 to December *** patients were randomly divided into two *** the operation of tooth extraction,17 patients were implanted with biomimetic MC(MC group),and other 17 patients were implanted with ordinary physically blended nHA/Col composite(nHA/Col group).X-ray positioning projection by auto-photographing was taken to test the distance between the lowest position and the neighboring CEJm-CEJd immediately,1 month and 3 months after the *** height of new bone formation of the MC group was significantly higher than the nHA/Col *** MC showed better clinical outcomes in the bone formation for extraction site preservation and would have broad application prospect in the field of oral and maxillofacial surgeries.

关键词： mineralized collagen biomimetic extraction site preservation bone formation height

The gas sensing properties of TiO_2 nanotubes synthesized by hydrothermal method

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Chinese Chemical Letters 2011年第5期22卷 603-606页

作者： Yan Li Wang Shun Tan Jia Wang zhi Jin Tan qiu Xia Wu Zheng Jiao Ming Hong Wu Institute of Nanochemistry and Nanobiology School of Environmental and Chemical Engineering Shanghai University Shanghai 200444 China

In this paper,the TiO_2 nanotubes were synthesized by hydrothermal method using a 10 mol/L NaOH aqueous solution at 150℃. The structure of prepared materials was characterized by X-ray diffraction（XRD）,transmission electron microscopy（TEM）. scanning electron microscope（SEM） and Brunauer-Emmett-Teller（BET）.The prepared TiO_2 nanotubes were used to prepare thick film gas sensors and the gas sensing properties to various gases were *** show the prepared TiO_2 nanotube gas sensors responses to ethanol under dry condition at 450℃.This could be attributed to the fact that it had high porous morphology and a higher pore volume,which can promote the diffusion of ethanol deep inside the films and improve the sensor response. Moreover,the gas sensor made with nanotubes exhibit high selective response towards ethanol gas compared with H_2,CO,acetone.

关键词： TiO_2 nanotubes Hydrothermal method Gas sensing

Effect of cenospheres addition on microstructure and properties of AZ91D alloy

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China Foundry 2015年第6期12卷 406-411页

作者： zhi-qiu Huang Si-rong Yu Ming Hu Ying-chun Shi Liu-yan Li Guo-yan Bo College of Materials Science and Engineering Jiamusi University College of Mechanical and Electronic Engineering China University of Petroleum

The cenospheres/AZ91D composites were fabricated by melt stir method. The phases, microstructure and tensile fracture morphology of the composites were analyzed using XRD, Olympus metallurgical microscopy and SEM methods. The thermal expansion coefficient(CTE) and tensile properties were measured. The results showed that the cenospheres distribute uniformly in the Mg alloy matrix and refine the matrix microstructure. Mg2 Si and MgO were found in addition to α-Mg and β-Mg17Al12 phases using XRD. The CTE of the composites reduced after the cenospheres are added. The yield strength of the composites increases significantly with an increase in the mass fraction and a decrease in the size of the cenospheres. The tensile strength of the composites achieves maximum when the mass fraction of cenospheres is 9wt.% and the size of cenospheres is 80 μm. The fracture mechanism of the composites is cleavage fracture.

关键词： cenospheres/AZ91D microstructure thermal expansion coefficient tensile strength

Photoluminescence of green InGaN/GaN MQWs grown on pre-wells

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Chinese Physics B 2020年第12期29卷 492-497页

作者： Shou-Qiang Lai Qing-Xuan Li Hao Long Jin-Zhao Wu Lei-Ying Ying zhi-Wei Zheng zhi-Ren qiu and Bao-Ping Zhang School of Electronic Science and Engineering Xiamen UniversityXiamen 361005China State Key Laboratory of Optoelectronic Materials and Technologies Sun Yat-sen UniversityGuangzhou 510275China

Photoluminescence(PL)characteristics of the structure consisting of green InGaN/GaN multiple quantum wells(MQWs)and low indium content InGaN/GaN pre-wells are *** PL peaks from pre-wells and green InGaN/GaN MQWs are *** peak energy values for both pre-wells and green InGaN/GaN MQWs display an S-shaped variation with *** addition,the differences in the carrier localization effect,defect density,and phonon-exciton interaction between the pre-wells and green InGaN/GaN MQWs,and the internal quantum efficiency of the sample are *** obtained results elucidate the mechanism of the luminescence characteristics of the sample and demonstrate the significant stress blocking effect of pre-wells.

关键词： InGaN/GaN photoluminescence pre-wells green LED

Role of the Chinese Herbal Medicine Xianhuayin on the Reversal of Premalignant Mucosal Lesions in the Golden Hamster Buccal Pouch

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International Journal of Oral Science 2010年第1期2卷 53-58页

作者： Yan-zhi Xu Yong-le qiu zhi-guang An Feng-ying Yang Department of Stomatology The Fourth Hospital of Hebei Medical University Shijiazhuang China

Aim To investigate the role of the Chinese herbal medicine Xianhuayin on the reversal of 7,12-dimethylbenz[a]anthracene （DMBA）-induced premalignant mucosal lesions in the oral buccal pouch of golden hamsters. Methodology The animals were randomly divided into a non-diseased control group （n=5） and an experimental group including 50 animals in which the buccal mucosa had been painted with DMBA （0.5% in acetone） to generate an oral mucosa premalignant lesion. Animals in the experi- mental group were further divided into Xianhuayin-treated group （n=30）, untreated prem＇alignant lesion group （n=10） and normal saline （NS）-treated group （n=10）. The cheek （buccal） pouch mucosa of the golden hamsters in each group was observed with light and electron microscopy eight weeks after intragastric administration with NS or Xianhuayin. Results In the non-diseased control group, the buccal mucosa was keratinized and stratified squamous epithelium under a light microscope. In the untreated premalignant lesion group, variable degrees of epithelial dysplasia was observed. The irregular epithelial mucosa gradually became distinct in the Xianhuayin-treated group. Scanning electronic microscopic （SEM） analysis showed that surface of the cells exhibited honeycomb structures in the hamster of untreated- group. The cells were morphologically irregular, overlapped and loosened in the untreated premalignant lesion group. Most of the cell surface exhibited honeycomb structure in the Xianhuayin-treated group. Transmission electronic micro- scopic （TEM） analysis showed that buccal mucosal epithelial cells were morphologically regular in the non-diseased control group. Desmosomes and tonofibrils were reduced and the nucleus was morphologically irregular in the untreated premalignant lesion group. In the Xianhuayin-treated group, the widening intercellular gap was gradually reduced, desmosomes and the cells becoming morphologically regular. No significant difference was observed between the hamster

关键词： Xianhuayin oral premalignant lesion golden hamster buccal pouch mucosa

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旋转柔性梁系统振动频响特性分析及振动抑制

振动与冲击 2008年第6期27卷 75-80,122页

作者：邱志成华南理工大学机械工程学院广州510641

航天器挠性附件或柔性机器人等柔性旋转梁系统的模态阻尼小,由于扰动,或者在调姿及转动时,大幅值的振动将持续很长时间,这将影响系统的稳定性和指向精度,因此,必须对振动进行主动控制。提出一种基于加速度传感器反馈的复合控制算法,快... 详细信息

航天器挠性附件或柔性机器人等柔性旋转梁系统的模态阻尼小,由于扰动,或者在调姿及转动时,大幅值的振动将持续很长时间,这将影响系统的稳定性和指向精度,因此,必须对振动进行主动控制。提出一种基于加速度传感器反馈的复合控制算法,快速控制系统设定点及转动过程的振动。建立挠性旋转梁试验平台,进行了基于加速度传感器和压电片传感器的试验模态激励分析、振动频响特性分析。并根据振动特性选取加速度反馈控制算法的相应参数,利用交流伺服电机驱动器抑制旋转梁设定点的振动、旋转过程的振动主动控制进行了试验研究。试验结果表明采用提出控制方法能够快速地抑制系统的振动,验证了特性分析和提出控制方法的可行性。

关键词：挠性转动梁振动频响特性分析振动主动控制加速度反馈控制实验研究

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基于垂直发射武器的火力交叉判断模型

兵工学报 2008年第11期29卷 1373-1378页

作者：桂秋阳邱志明海军装备研究院北京100161

文章就如何建立垂直发射武器的火力散布体模型及如何判断火力交叉的发生进行了研究。采用四元数方法建立了垂直发射武器的弹道仿真模型,通过仿真定性分析了不同误差因素对于弹道散布的影响;分析了初始扰动对弹道散布的影响,得到了散布... 详细信息

文章就如何建立垂直发射武器的火力散布体模型及如何判断火力交叉的发生进行了研究。采用四元数方法建立了垂直发射武器的弹道仿真模型,通过仿真定性分析了不同误差因素对于弹道散布的影响;分析了初始扰动对弹道散布的影响,得到了散布半径随时间变化的函数;建立了以理想弹道为轴线的垂直发射武器火力散布体模型,模型中考虑了时间上的控制因素,减小了导弹武器空间散布体的范围,并提出了模型的解算方法。所建立的模型能够较为准确地描述不同武器火力散布的情况,并能对火力交叉做出判断。

关键词：飞行器发射、飞行技术弹道仿真火力兼容垂直发射四元数