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Changing patterns of traumatic bile duct injuries:a review of forty years experience

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World Journal of Gastroenterology 2002年第1期8卷 5-12页

作者： zhi-qiang huang Xiao-qiang huang Research Institute of General Surgery,The General Hospital of Chinese PLA,Beijing 100853,China Research Institute of General Surgery The General Hospital of Chinese PLA Beijing 100853China. zhiqianghuang2000@***

AIM:To summarize the experiences of treating bile ductinjuries in 40 years of clinical ***:Based on the experience of more than 40 yearsof clinical work,122 cases including a series of 61 bile ductinjuries of the Southwest Hospital,Chongqing,and 42cases(1989-1997)and 19 cases(1998-2001)of the GeneralHospital of PLA,Beijing,cases were reviewed with specialreference to the pattern of injury.A series of cases of theliver and the biliary tract injuries following interventionaltherapy for hepatic tumors,most often hemangioma of theliver,were *** medical literature from 1995 to1999 dealing with 2742 traumatic bile duct strictures ***:There was a changing pattern of the bile *** most of the cases of bile duct injuriesresulted from open *** types of traumasuch as laparoscopic cholecysiectomy(LC)and hepaticsurgery were increased in recent ***,serioushepato-biliary injuries following HAE using sclerotic agentssuch as sodium morrhuate and absolute ethanol for thetreatment of hepatic hemangiomas were encountered inrecent *** in how to avoid bile duct injuryand to treat traumatic biliary strictures were ***:Traumatic bile duct stricture is one of theserious complications of hepato-biliary surgery,itsprevalence seemed to be increased in recent *** of bile duct injury was also changed and has becomemore *** therapy with sclerosingagents may cause serious hepatobiliary complications andshould be avoided.

关键词：创伤性胆管损伤临床分析胆管外科并发症医源性损伤

Colon metastasis of chromophobe renal cell carcinoma with sarcomatoid change

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Chinese Medical Journal 2012年第18期125卷 3352-3354页

作者： ZHAO Wei-ping YU Yan-lan CHEN zhi-qiang huang Xue-feng ZHANG zhi-gen Department of Urology Sir Run-Run Shaw Hospital College ofMedicine Zhejiang University HangzhouChina Zhejiang 310006

We present a rare case of colonic metastasis of renal cell carcinoma （RCC） and review the literature. A 54-year-old male was referred to our hospital with a history of bloody stools and fever. Aright kidney tumor measuring about 10 cm in diameter was found by abdominal computed tomography. Right radical nephrectomy and a right hemicolectomy with ileotransversostomy were performed. Pathological diagnosis was chromophobe RCC with sarcomotoid change involving the colon. Chromophobe RCC with sarcomotoid change is very rare.

关键词： renal cell carcinoma neoplasm metastasis

Effect of arterioportal shunting in radical resection of hilar cholangiocarcinoma

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Chinese Medical Journal 2010年第22期123卷 3217-3219页

作者： CHEN Yong-liang huang zhi-qiang huang Xiao-qiang DONG Jia-hong DUAN Wei-dong LIU zhi-wei ZHANG Xuan LIANG Yu-rong CHEN Ming-yi Department of Hepatobiliary Surgery General Hospital of Chinese People's Liberation Army Beijing 100853 China

Background The resection and reconstruction of the hepatic artery is often required in radical surgery for hilar cholangiocarcinoma. In this study, we report our experience in performing arterioportal shunting as an alternative for the arterial reconstruction. Methods Four patients with hilar cholangiocarcinoma underwent extended left hepatectomy and caudate Iobectomy combined with en bloc resection of the hepatic artery and arterioportal shunting with restriction of the arterial caliber. The efficacy of arterioportal shunting was assessed by computed tomography angiography （CTA）. Results All the four patients recovered uneventfully without any complications. CTA showed a patent shunt and normal liver regeneration. No signs of portal hypertension were found at one year of follow-up. Conclusions Arterioportal shunting with restriction of the arterial caliber appears to be a feasible and safe alternative for the microvascular reconstruction after hepatic artery resection in radical surgery for hilar cholangiocarcinoma.

关键词： arterioportal shunting hilar cholangiocarcinoma restriction of the arterial caliber

New development of biliary surgery in China

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World Journal of Gastroenterology 2000年第2期6卷 187-192页

作者： zhi qiang huang The Research Institute of General Surgery,The General Hospital of PLA,Beijing 100853,China 解放军总医院北京

CHARACTERISTICS OF BILIARY CALCULOUSDISEASES IN CHINA:THE CHANGING SCOPEDiseases of the biliary tract in China is complicatedwith the prevalence of primary infection of the bileduct *** the middle of the 20th century,biliary infection,biliary parasitic infestation,andbiliary stones made up the three chief componentsof biliary diseases in *** to the

关键词： biliary surgery cholelithiasis intrahepatic stones carcinoma gallbladder carcinoma bile duct

Precise Asymptotics in Limit Theorems for a Supercritical Branching Process with Immigration in a Random Environment

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Acta Mathematica Sinica,English Series 2024年第8期40卷 1850-1874页

作者： Chun Mao huang Rui ZHANG zhi qiang GAO Department of Mathematics Harbin Institute of Technology(Weihai)Weihai 264209P.R.China School of Mathematical Sciences Beijing Normal UniversityBeijing 100875P.R.China

Let(Zn)be a supercritical branching process with immigration in an independent and identically distributed random *** necessary moment conditions,we show the exact convergence rate in the central limit theorem on log Zn and establish the corresponding local limit theorem by using the moments of the natural submartingale and the convergence rates of its *** similar approach and with the help of a change of measure,we also present the so-called integrolocal theorem and integral large deviation theorem to characterize the precise asymptotics of the upper large deviations.

关键词： Branching process with immigration random environment central limit theorem large deviation

Portal venous arterialization resulting in increased portal inflow and portal vein wall thickness in rats

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World Journal of Gastroenterology 2008年第43期14卷 6681-6688页

作者： Wen-Gang Li Yong-Liang Chen Jing-Xi Chen Lei Qu Bin-Dang Xue zhi-Hai Peng zhi-qiang huang Department of Hepatobiliary Pancreas and Vessel Surgery Xiamen First Hospital Attached Fujian Medical University Xiamen 361003 Fujian Province China Institute of Hepatobiliary Surgery General Hospital ofPLA Beijing 100853 China Image Processing Centre Beijing University of Aeronautics and Astronautics Beijing 100083 China

AIM： To explore the influence of portal vein hemodynamic changes after portal venous arterialization （PVA） on peribiliary vascular plexus （PVP） morphological structure and hepatic pathology, and to establish a theoretical basis for the clinical application of PVA. METHODS： Sprague-Dawley rats were randomly divided into control and PVA groups. After PVA, hemodynamic changes of the portal vein and morphological structure of hepatohilar PVP were observed using Doppler ultrasound, liver function tests, ink perfusion transparency management and three-dimensional reconstruction of computer microvisualization, and pathological examination was performed on tissue from the bile duct wall and the liver. RESULTS： After PVA, the cross-sectional area and blood flow of the portal vein were increased, and the increase became more significant over time, in a certain range. If the measure to limit the flow in PVA was not adopted, the high blood flow would lead to dilatation of intrahepatic portal vein and its branches, increase in collagen and fiber degeneration in tunica intima. Except glutamic pyruvic transaminase （GPT）, other liver function tests were normal. CONCLUSION： Blood with a certain flow and oxygen content is important for filling the PVP and meeting the oxygen requirement of the bile duct wall. After PVA, It is the anatomic basis to maintain normal morphology of hepatohilar bile duct wall that the blood with high oxygen content and high flow in arterialized portal vein may fill PVP by collateral vessel reflux. A adequate measure to limit blood flow is necessary in PVA.

关键词： Peribiliary vascular plexus Portal venous arterialization Liver transplantation Bile duct neoplasms Three-dimensional reconstruction Hemodynamics

Evolution of surgical treatment of intrahepatic lithiasis in China

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World Journal of Gastroenterology 1997年第3期3卷 3-5页

作者： huang zhi qiang and huang Xiao qiang Keywords cholelithiasis/surgery bile ducts, intrahepatic hepatectomy choledochostomy

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关键词： intrahepatic

Detection of hepatitis C virus NS5 protein and genome in Chinese carcinoma of the extrahepatic bile duct and its significance

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World Journal of Gastroenterology 2000年第6期6卷 800-804页

作者： Ming Yi Chen zhi qiang huang Le Zhen Chen Ya Bing Gao Rui Yun Peng De Wen Wang Research Institute of General Surgery Department of Hepatobiliary SurgeryGeneral Hospital of the Chinese Peoples Liberation Army(PLA)Beijing 100853China Department of Pathology General Hospital of PLABeijing 100855China Experimental Pathologic Laboratory Institute of Medical RadiologyAcademy of Military Medical SciencesBeijing 100850China

AIM To investigate the hepatitis C virus(HCV)infection in the tissues of carcinoma ofextrahepatic bile duct and study *** HCV NS5 protein and HCV RNA weredetected by labeled streptavidin biotin(LSAB)method and in situ reverse transcriptionpolymerase chain reaction(IS-RT-PCR)insections of 51 cases of carcinoma ofextrahepatic bile duct and 34 cases of controlgroup(without malignant biliary disease).RESULTS In 51 cases of carcinoma ofextrahepatic bile duct,HCV NS5 protein wasdetected in 14(27.5%),which was clearlystained in the cytoplasm of cancer cell but not inthe nucleus or cell *** RNA wasdetected in 18(35.4%),which was located inthe nucleus of cancer cell in 12 cases and in thecytoplasm in 6 *** NS5 protein and RNAcoexistence was found in 2 *** 34 cases ofcontrol group,HCV RNA was detected in 2(5.9%).HCV NS5 protein and RNA positive cellswere found either scattered or in *** The prevalence of hepatitis C viral infection in the tissues of carcinoma ofextrahepatic bile duct was significantly higherthan in control group(X^2=9.808,P=0.002).The findings suggest a correlation between HCVinfection and carcinoma of extrahepatic bileduct,which is different from the *** infection might be involved inthe development of carcinoma of extrahepaticbile duct.

关键词： hepatitis C virus bile duct neoplasm polymerase chain reaction immunohistochemistry risk factors genes, suppressor, tumor transfection genome

Post-pancreaticoduodenectomy hemorrhage:risk factors, managements and outcomes

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Hepatobiliary & Pancreatic Diseases International 2014年第5期13卷 513-522页

作者： Jian Feng Yong-Liang Chen Jia-Hong Dong Ming-Yi Chen Shou-Wang Cai zhi-qiang huang Institute of Hepatobiliary Surgery Chinese PLA General Hospital

BACKGROUND： Post-pancreaticoduodenectomy（PD） hemorrhage（PPH） is an uncommon but serious complication. This retrospective study analyzed the risk factors, managements and outcomes of the patients with ***： A total of 840 patients with PD between 2000 and2010 were retrospectively analyzed. Among them, 73 patients had PPH： 19 patients had early PPH and 54 had late *** assessment included the preoperative history of disease,pancreatic status and surgical techniques. Other postoperative complications were also ***： The incidence of PPH was 8.7%（73/840）. There were no independent risk factors for early PPH. Male gender（OR=4.40, P0.02）, diameter of pancreatic duct（OR=0.64,P0.01）, end-to-side invagination pancreaticojejunostomy（OR=5.65, P0.01）, pancreatic fistula（OR=2.33, P0.04）and intra-abdominal abscess（OR=12.19, P0.01） were the independent risk factors for late PPH. Four patients with early PPH received conservative treatment and 12 were treated surgically. As for patients with late PPH, the success rate of medical therapy was 27.8%（15/54）. Initial endoscopy was operated in 12 patients（22.2%）, initial angiography in 19（35.2%）,and relaparotomy in 15（27.8%）. Eventually, PPH resulted in 19 deaths. The main causes of death were multiple organ failure,hemorrhagic shock, sepsis and uncontrolled ***： Careful and ongoing observation of hemorrhagic signs, especially within the first 24 hours after PD or within the course of pancreatic fistula or intra-abdominal abscess, is recommended for patients with PD and a prompt management is necessary. Although endoscopy and angiography are the standard procedures for the management of PPH,surgical approach is still irreplaceable. Aggressive prevention of hemorrhagic shock and re-hemorrhage is the key to treat PPH.

关键词： pancreaticoduodenectomy hemorrhage risk factors management outcome