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Effect of treatment course of comprehensive intervention with Traditional Chinese Medicine on mortality of acquired immunodeficiency syndrome patients treated with combined antiretroviral therapy

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Journal of Traditional Chinese Medicine 2016年第4期36卷 411-417页

作者： Guo Huijun Wang jian Li Zhengwei jiang Ziqiang Xu Qianlei Xu Liran Department of Acquired Immune Deficiency Syndrome AIDS Treatment and Research Center the First Affiliated Hospital of Henan University of Traditional Chinese Medicine Traditional Chinese Medicine Center for Acquired Immune Deficiency Syndrome Prevention and Treatment China Academy of Traditional Chinese Medicine

OBJECTIVE:To investigate the effect of a treatment course of comprehensive intervention with Traditional Chinese Medicine(TCM) on the mortality of patients with acquired immunodeficiency syndrome(AIDS) treated with combined antiretroviral therapy(c ART).METHODS:AIDS patients who had taken c ART in a national TCM human immunodeficiency virus treatment trial program(NTCMTP) before 2009 were enrolled in this study and followed for 36 months from November *** enrolled in the NTCMTP in 2004 were taken as the first group,those enrolled in 2006 as the second group,and those enrolled in 2009 as the third *** survival rates were calculated by the life table *** curves for subgroups were compared by the log-rank *** ratios were calculated with a Cox proportional hazards ***:A total of 1443 AIDS patients were followed for 3 years(4198 person-years).During this period,91(6.3%) patients died and 13(0.9%) were lost to *** total mortality rate was 2.17/100 *** mortality rate of patients enrolled in the NTCMTP in 2004 was 1.49/100 person-years,which was lower than that of patients enrolled in 2006(2.23/100 person-years) and 2009(3.48/100 person-years).After adjusting for other factors,a shorter time of treatment with TCM,male sex,older age,lower CD4 + T-cell counts,and long-term treatment with c ART were risk factors of ***:Long-term treatment with TCM decreased the mortality risk of AIDS *** such as being male,older age,CD4+ T-cell counts,and time of treatment with TCM and c ART were correlated with mortality.

关键词： Acquired immunodeficiency syndrome Antiretroviral therapy highly active Mortality Medicine Chinese traditional Retrospective cohort study

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虚拟生产系统的自适应动态调度机理及算法

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计算机集成制造系统 2006年第9期12卷 1444-1452页

作者：李琳江志斌上海交通大学机械与动力工程学院工业工程与管理系上海200030

为解决动态制造环境下虚拟生产系统的动态调度问题,提出了一种基于事件驱动的自适应动态调度方法。在该方法中,自适应动态调度机理首先通过检测获得虚拟生产系统所面临的动态事件,进而分析动态事件对调度产生的局部影响,并制定相应的自... 详细信息

为解决动态制造环境下虚拟生产系统的动态调度问题,提出了一种基于事件驱动的自适应动态调度方法。在该方法中,自适应动态调度机理首先通过检测获得虚拟生产系统所面临的动态事件,进而分析动态事件对调度产生的局部影响,并制定相应的自适应措施和规则,然后在自适应规则的指导下,采用改进的启发式受影响操作重调度算法作为自适应动态调度的算法,来确定调度中的受影响操作并对其做出相应的局部调整,从而以一种自适应的方式快速而平稳地完成虚拟生产系统的动态调度。最后,通过与一种典型的整体重调度方法(基于多智能体的调度方法)的比较,验证了该方法的可行性和有效性。

关键词：虚拟生产系统动态调度受影响操作重调度算法

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Effects of viral infection and microbial diversity on patients with sepsis:A retrospective study based on metagenomic next-generation sequencing

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World Journal of Emergency Medicine 2021年第1期12卷 29-35页

作者： Li-wei Duan Jin-long Qu jian Wan Yong-hua Xu Yi Shan Li-xue Wu Jin-hao Zheng Wei-wei jiang Qi-tong Chen Yan Zhu jian Zhou Wen-bo Yu Lei Pei Xi Song Wen-fang Li Zhao-fen Lin Department of Emergency and Critical Care Medicine Changzheng Hospitalthe Second Military Medical UniversityShanghai 200003China Department of Emergency and Critical Care Medicine Pudong New Area People’s HospitalShanghai 201299China

BACKGROUND: The study aims to investigate the performance of a metagenomic next-generationsequencing (NGS)-based diagnostic technique for the identifi cation of potential bacterial and viral infectionsand eff ects of concomitant viral infection on the survival rate of intensive care unit (ICU) sepsis ***: A total of 74 ICU patients with sepsis who were admitted to our institution from February1, 2018 to June 30, 2019 were enrolled. Separate blood samples were collected from patients for bloodcultures and metagenomic NGS when the patients’ body temperature was higher than 38 °C. Patients’demographic data, including gender, age, ICU duration, ICU scores, and laboratory results, were *** correlations between pathogen types and sepsis severity and survival rate were ***: NGS produced higher positive results (105 of 118;88.98%) than blood cultures(18 of 118;15.25%) over the whole study period. Concomitant viral infection correlated closelywith sepsis severity and had the negative effect on the survival of patients with sepsis. However,correlation analysis indicated that the bacterial variety did not correlate with the severity of ***: Concurrent viral load correlates closely with the severity of sepsis and thesurvival rate of the ICU sepsis patients. This suggests that prophylactic administration of antiviraldrugs combined with antibiotics may be benefi cial to ICU sepsis patients.

关键词： Sepsis Metagenomic next-generation sequencing Viral infections Bacterial infections Microbial diversity

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双“帐户”视角下农村土地承包经营纠纷的个体诉讼决策研究——以集体林地纠纷诉讼为例

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浙江工商大学学报 2019年第4期 70-78页

作者：蒋瞻蔡志坚刘依依南京林业大学经济管理学院

引进"经济学帐户"和"心理帐户"决策原则,以集体林地承包经营纠纷诉讼案件为例,分析农村土地承包经营纠纷中个体诉讼者的决策依据,并探索是否可以通过改变决策者决策原则以减少诉讼的发生。结果显示:绝大多数个体诉讼决策者以"经济学帐户... 详细信息

引进"经济学帐户"和"心理帐户"决策原则,以集体林地承包经营纠纷诉讼案件为例,分析农村土地承包经营纠纷中个体诉讼者的决策依据,并探索是否可以通过改变决策者决策原则以减少诉讼的发生。结果显示:绝大多数个体诉讼决策者以"经济学帐户"作为决策依据,但也存在根据"心理帐户"原则进行决策的决策者。针对后一类决策,理论上可通过说服个体决策者改变其心理帐户设置,从而改变其"诉讼"决策为"和解"从而降低诉讼发生率,但实践中受到纠纷诉讼对象与现有纠纷调处机制的影响,个体纠纷诉讼决策者与经济组织和其他个体间的纠纷存在和解空间,但难以改变与村委会间的纠纷诉讼决策。

关键词：心理帐户经济学帐户承包经营纠纷成本收益分析集体林地

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Absence of superconductivity in Nd0.8Sr0.2NiOx thin films without chemical reduction

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Rare Metals 2020年第4期39卷 368-374页

作者： Xiao-Rong Zhou Ze-Xin Feng Pei-Xin Qin Han Yan Shuai Hu Hui-Xin Guo Xiao-Ning Wang Hao-jiang Wu Xin Zhang Hong-Yu Chen Xue-Peng Qiu zhi-Qi Liu School of Materials Science and Engineering Beihang UniversityBeijing 100191China Shanghai Key Laboratory of Special Artificial Microstructure Materials and Technology and Pohl Institute of Solid-State PhysicsSchool of Physics Science and EngineeringTongji UniversityShanghai 200092China

The recently reported 9-15 K superconductivity in Nd0.8Sr0.2NiO2/SrTi03 heterostructures that were fabricated by a soft-chemical topotactic reduction approach based on precursor Nd0.8Sr0.2NiO3 thin films deposited on SrTiO3 substrates,has excited an immediate surge of research *** explore an alternative physical path instead of chemical reduction to realizing superconductivity in this compound,using pulsed laser deposition,we systematically fabricated 63 Nd0.8Sr0.2NiOx(NSNO)thin films at a wide range of oxygen partial pressures on various oxide *** measurements did not find any signature of superconductivity in all the 63 thin-film *** the oxygen content reducing in the NSNO films by lowering the deposition oxygen pressure,the NSNO films are getting more resistive and finally become ***,we tried to cap a 20-nm-thick amorphous LaAlO3 layer on a Nd0.8Sr0.2NiO3 thin film deposited at a high oxygen pressure of 20 Pa to create oxygen vacancies on its surface and did not succeed in obtaining higher conductivity *** experimental results together with the recent report on the absence of superconductivity in synthesized bulk Nd0.8Sr0.2NiO2 crystals suggest that the chemical reduction approach could be unique for yielding superconductivity in NSNO/SrTiO3 ***,SrTiO3 substrates could be reduced to generate oxygen vacancies during the chemical reduction process as well,which may thus partially contribute to conductivity.

关键词： Superconductivity Nd0.8Sr0.2NiOx Thin films Chemical reduction

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Unconventional lattice dynamics in few-layer h-BN and indium iodide crystals

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Chinese Physics B 2018年第8期27卷 415-422页

作者： Gan Hu jian-Qi Huang Ya-Ning Wang Teng Yang Bao-Juan Dong Ji-Zhang Wang Bo Zhao Sajjad Ali zhi-Dong Zhang Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaHefei 230026China College of Sciences Liaoning Shihua UniversityFushun 113001China

Unusual quadratic dispersion of flexural vibrational mode and red-shift of Raman shift of in-plane mode with increas- ing layer-number are quite common and interesting in low-dimensional materials, but their physical origins still remain open questions. Combining ab initio density functional theory calculations with the empirical force-constant model, we study the lattice dynamics of two typical two-dimensional （2D） systems, few-layer h-BN and indium iodide （InI）. We found that the unusual quadratic dispersion of flexural mode frequency on wave vector may be comprehended based on the com- petition between atomic interactions of different neighbors. Long-range interaction plays an essential role in determining the dynamic stability of the 2D systems. The frequency red-shift of in-plane Raman-active mode from monolayer to bulk arises mainly from the reduced long-range interaction due to the increasing screening effect.

关键词： flexural mode quadratic dispersion long-range interaction frequency redshift dielectric screen-ing

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Effect of Zn, Cu and Ni addition on microstructure and mechanical properties of ascast Mg-Dy alloys

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China Foundry 2016年第1期13卷 54-58页

作者： Guang-li Bi Xiao-mei Luo Jing jiang Yong-gang Zhang jian-ji Xu Jie-ming Chen Yuan-dong Li Ying Ma State Key Laboratory of Advanced Processing and Recycling of Nonferrous Metals Lanzhou University of Technology Key Laboratory of Nonferrous Metal alloys and Processing Ministry of Education Lanzhou University of Technology

This paper presents some research information on the effects of Zn, Cu and Ni on the microstructure and mechanical properties of as-cast Mg-2Dy(at.%) alloys. The Mg-2Dy alloy is composed of α-Mg and Mg24Dy5 phases. With the addition of 0.5at.%Zn, 0.5at.%Cu and 0.5at.%Ni, respectively, besides α-Mg, the long period stacking order(LPSO) phases containing Zn, Cu, and Ni precipitated in the α-Mg interdentritic boundary. The addition of Ni effectively refined the dendrite arm spacing. The as-cast Mg-2Dy-0.5Ni alloy exhibited the best tensile strengths and elongation. The better mechanical properties were mainly attributed to small secondry dendrite arm spacing(SDAS) and high volume fraction of LPSO phases.

关键词： Mg-Dy-Zn(Cu,Ni) alloys LPSO phase microstructure mechanical properties

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线性走时插值射线追踪算法的改进

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湖南大学学报（自然科学版） 2014年第1期41卷 39-44页

作者：卢江波方志湖南大学土木工程学院湖南长沙410082

在LTI(Linear Travel-time Interpolation)射线追踪算法基础上提出的扩张-收缩扫描算法能正确追踪直达波、绕射波和回波的射线路径,但其存在计算效率低、收敛速度慢的问题.采用交叉扫描方式对扩张-收缩扫描算法进行改进,并由此提出了基... 详细信息

在LTI(Linear Travel-time Interpolation)射线追踪算法基础上提出的扩张-收缩扫描算法能正确追踪直达波、绕射波和回波的射线路径,但其存在计算效率低、收敛速度慢的问题.采用交叉扫描方式对扩张-收缩扫描算法进行改进,并由此提出了基于交叉扫描方式的扩张-收缩扫描改进算法.理论分析及数值模拟结果表明:改进算法在保留了原扩张收缩扫描算法所有优点的同时,具有更高的计算效率;当模型网格尺寸划分较细时,改进算法在计算效率上的优势更为显著.

关键词：射线追踪 LTI算法交叉扫描扩张收缩扫描法改进算法

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Accelerating Data Transfer in Dataflow Architectures Through a Look-Ahead Acknowledgment Mechanism

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Journal of Computer Science & Technology 2022年第4期37卷 942-959页

作者： Yu-Jing Feng De-jian Li Xu Tan Xiao-Chun Ye Dong-Rui Fan Wen-Ming Li Da Wang Hao Zhang zhi-Min Tang State Key Laboratory of Computer Architecture Institute of Computing TechnologyChinese Academy of SciencesBeijing 100190China Beijing Smartchip Microelectronics Technology Company Limited Beijing 100000China School of Computer and Control Engineering University of Chinese Academy of SciencesBeijing 100190China

The dataflow architecture,which is characterized by a lack of a redundant unified control logic,has been shown to have an advantage over the control-flow architecture as it improves the computational performance and power efficiency,especially of applications used in high-performance computing(HPC).Importantly,the high computational efficiency of systems using the dataflow architecture is achieved by allowing program kernels to be activated in a simultaneous ***,a proper acknowledgment mechanism is required to distinguish the data that logically belongs to different *** solutions include the tagged-token matching mechanism in which the data is sent before acknowledgments are received but retried after rejection,or a handshake mechanism in which the data is only sent after acknowledgments are ***,these mechanisms are characterized by both inefficient data transfer and increased area *** performance of the dataflow architecture depends on the efficiency of data *** order to optimize the efficiency of data transfer in existing dataflow architectures with a minimal increase in area and power cost,we propose a Look-Ahead Acknowledgment(LAA)*** accelerates the execution flow by speculatively acknowledging ahead without *** simulation analysis based on a handshake mechanism shows that our LAA increases the average utilization of computational units by 23.9%,with a reduction in the average execution time by 17.4%and an increase in the average power efficiency of dataflow processors by 22.4%.Crucially,our novel approach results in a relatively small increase in the area and power consumption of the on-chip logic of less than 0.9%.In conclusion,the evaluation results suggest that Look-Ahead Acknowledgment is an effective improvement for data transfer in existing dataflow architectures.

关键词： dataflow model control-flow model high-performance computing application data transfer power efficiency

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External validation of EncephalApp Stroop test to screen minimal hepatic encephalopathy patients with nonalcoholic cirrhosis

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World Journal of Hepatology 2024年第12期16卷 1450-1457页

作者： Ting-Ting jiang Xiao-Li Liu Hao Yu Ya-Xuan Sun Jia-Yan Zhou zhi-Yun Yang Guang Chen Center of Integrative Medicine Beijing Ditan Hospital Affiliated to Capital Medical UniversityBeijing 100015China T.H.Chan School of Public Health Harvard UniversityBostonMA 02115United States School of Medicine Stanford UniversityStanfordCA 94305United States LKS Faculty of Medicine University of Hong KongHong Kong 999077China

BACKGROUND Neurocognitive impairment,including minimal hepatic encephalopathy(MHE)and overt hepatic encephalopathy,is one of the most common complications of all types of primary liver diseases,such as hepatitis B,biliary cholangitis,and autoi-mmune *** EncephalApp Stroop test is a smartphone application-based test that is time-saving for MHE ***,neurocognitive impairment is different between alcoholic cirrhosis patients and nonalcoholic cirrhosis pa-tients,so the cutoff value for MHE diagnosis might be *** To validate the Stroop test in nonalcoholic cirrhosis *** This external validation was performed at the National Center for Infectious Diseases(Beijing).Liver cirrhosis patients aged between 18 and 65 years who voluntarily enrolled in the study and provided signed informed consent were *** Psychometric Hepatic Encephalopathy Score(PHES)test was used as the standard diagnostic criterion for *** EncephalApp Stroop test was then performed on the iPad,including two sessions of tests(“off”and“on”)to measure patients’ability to differentiate between numbers and *** assessed the performance of the EncephalApp Stroop test in terms of the area under the curve(AUC),sensitivity,specificity,positive predictive value,and negative predictive value,with the PHES as the standard *** A total of 160 nonalcoholic cirrhosis patients were included in this validation study,including 87(54.4%)patients without MHE and 73(45.6%)patients with *** the PHES as the gold standard,the EncephalApp Stroop test performed well for nonalcoholic liver cirrhosis patients in terms of“off”time[AUC:0.85,95%confidence interval(CI):0.79-0.91]and“on+off”time(AUC:0.85,95%CI:0.80-0.91);however,total runs of“off”session(AUC:0.61,95%CI:0.52-0.69),total runs of“on”session(AUC:0.57,95%CI:0.48-0.65),and“on–off”time(AUC:0.54,95%CI:0.44-0.63)were comparatively *** optimal cutoff points were“off”time>101.93 seconds and“on+off”

关键词： Minimal hepatic encephalopathy Nonalcoholic cirrhosis EncephalApp Stroop test Diagnosis Screening

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