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Piggyback liver transplant techniques in the surgical management of urological tumors with inferior vena cava tumor thrombus

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Chinese Medical Journal 2009年第18期122卷 2155-2158页

作者： ji zhi-gang XUE Chong LI Han-zhong WANG Hui-jun XIE Yi LIU Guan-hua Department of Urology Peking Union Medical College Hospital Chinese Academy of Medical Sciences Beijing 100730 China

Background An important characteristic of renal cell carcinomas and adrenal tumors is that these tumors may expand into the renal vein and inferior vena cava, and transform into tumor thrombi. This study was to evaluate the use of piggyback liver transplant techniques for surgical management of urological tumors with inferior vena cava tumor thrombus. Methods Nineteen patients with renal cell carcinomas or adrenal tumors with inferior vena cava tumor thrombus were treated from November 1995 to April 2008. Their ages ranged from 29 years to 76 years （mean 54 years）. The extent of tumor thrombus was infrahepatic （level Ⅰ） in 2, retrohepatic （level Ⅱ） in 7, suprahepatic （level Ⅲ） in 6, and intra-atrial （level Ⅳ） in 4 patients. We used cardiopulmonary bypass with deep hypothermic circulatory arrest to remove the thrombi in 3 cases of level IV and in 2 cases of level Ⅲ. In all level Ⅱ, 4 level Ⅲ, and 2 level IV cases, we used piggyback liver transplant techniques to mobilize the liver off of the inferior vena cava and to separate the inferior vena cava from the posterior abdominal wall. Results Mean operative time was 5.1 hours, mean estimated blood loss was 2289 ml and mean blood transfusion was 12.84 U. One patient with adrenal cortical carcinoma and level Ⅳ thrombus died in the immediate postoperative period. Three patients were lost to follow up, and the other 15 survivors were followed from 5 months to 56 months. Eight of these 15 patients died due to metastasis; however 7 were still alive at the last follow-up. Conclusions An aggressive surgical approach is the only hope for curing patients diagnosed with urological tumors combined with inferior vena cava tumor thrombus. The use of piggyback liver transplant techniques to mobilize the liver off of the inferior vena cava provides excellent exposure of the inferior vena cava. Patients with a level Ⅱ or level Ⅲ inferior vena cava thrombus may be treated without using cardiopulmonary bypass.

关键词： renal cell carcinoma tumor thrombus inferior vena cava liver transplantation

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Visualizing the landscape of appendiceal tumor research after 2010: A bibliometric study

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1894-1909页

作者： jia-Nan ji zhi-Bin Yin Department of General Surgery The Affiliated Huishan Hospital of Xinglin CollegeNantong UniversityWuxi Huishan District People’s HospitalWuxi 214187Jiangsu ProvinceChina

BACKGROUND Despite the rarity of appendiceal tumors,research in this field has intensified,resulting in a growing number of studies and published ***,no comprehensive bibliometric analysis has specifically addressed appendiceal *** To offer a thorough analysis of the current landscape and future trends in appendiceal tumor *** In our bibliometric analysis studies,we explored the Web of Science Core Collection *** bibliographic details of the chosen publications were automatically converted and analyzed using the bibliometric package in the R ***,we employed VoSviewer to create cooperation network maps for countries,institutions,and authors,as well as clustering maps for ***,CiteSpace,another software tool,was utilized to build dual-map overlays of journals and analyze references with citation *** Our study included 780 English-language articles published after *** number of related publications and citations has increased in the past *** United States leads in this area,but there is a need to improve cooperation and communication among countries and ***-occurrence analysis also revealed close collaboration among different *** of Surgical Oncology was the most influential journal in this *** of references with high cocitations and references with citation bursts,consistent with analysis of keywords and hotspots,indicated that current research primarily centers on the classification and management of appendiceal mucinous neoplasms and consequent pseudomyxoma *** the abundance of clinical studies,a greater number of in-depth basic research studies should be *** Current research on appendiceal tumors focuses on classification and management of appendiceal mucinous neoplasms and pseudomyxoma *** collaboration and basic research are vital for further advancement.

关键词： Appendiceal tumor Appendix Mucinous neoplasms Bibliometric analysis Pseudomyxoma peritonei

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Diagnosis and Treatment of Primary Adult Renal Sarcoma

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Chinese Medical Sciences Journal 2011年第3期26卷 172-174页

作者： Zhong-ming Huang Han-zhong Li zhi-gang ji Bing-bing Shi Department of Urology Peking Union Medical College HospitalChinese Academy of Medical Sciences ＆ Peking Union Medical CollegeBeijing 100730China

Objective To investigate the clinical characteristics of primary adult renal *** A total of 1654 cases with adult renal tumors were treated during 1985 to 2009 in Peking Union Medical College *** all,17 cases were diagnosed as primary renal sarcoma and underwent radical *** clinical features of 17 such patients were retrospectively *** The first symptom of 10(59%) cases in all renal sarcomas was abdominal *** pathological diagnosis was leiomyosarcoma(7 cases),rhabdomyosarcoma(2 cases),malignant fibrous histiocytoma(2 cases),low-differentiated sarcoma(2 cases),chromophobe renal cell carcinoma coexisting with liposarcoma(1 case),fibrosarcoma(1 case),embryonic sarcoma(1 case) and leiomyosarcoma(1 case).One patient died of tumor thrombus of the inferior vena cava during ***,15 cases were regularly followed up for 4 to 60 *** now,1 had tumor-free survival for 9 months,and the other 14 cases died 2-38 months after the operation with a median survival time of 18(range,5-60) *** median survival time of leiomyosarcoma group was 28(range,11-60) months,and 2 cases of malignant fibrous histiocytoma died 4 and 8 months after the operation *** The primary renal sarcoma has the clinical symptom similar with advanced renal cell carcinoma and has poor *** might have relative good prognosis.

关键词： renal sarcoma adult pathology

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Aldol Condensation of Acetylferrocene under Ultrasound

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Chinese Chemical Letters 2003年第7期14卷 663-666页

作者： Shun Jun ji, zhi Liang SHEN, Shun Yi WANG College of Chemistry and Chemical Engineering, Suzhou University, Suzhou 215006 Coll. of Chem./Chemical Engineering Suzhou University Suzhou 215006 China

Aldol condensation of acetylferrocene with aromatic aldehydes afforded ferroceny- lenones in 76%-92% yields under ultrasound at room temperature.

关键词： Acetylferrocene aldol condensation ferrocenylenone ultrasonic irradiation.

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Uncertainty and sensitivity analysis of in-vessel phenomena under severe accident mitigation strategy based on ISAA-SAUP program

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Nuclear Science and Techniques 2024年第1期35卷 108-123页

作者： Hao Yang ji-Shen Li zhi-Ran Zhang Bin Zhang jian-Qiang Shan School of Nuclear Science and Technology Xi’an Jiaotong UniversityXi’an 710049China State Key Laboratory of Multiphase Flow in Power Engineering Xi’an Jiaotong UniversityXi’an 710049China

The phenomenology involved in severe accidents in nuclear reactors is highly ***,integrated analysis programs used for severe accident analysis heavily rely on custom empirical parameters,which introduce considerable ***,in recent years,the field of severe accidents has shifted its focus toward applying uncertainty analysis methods to quantify uncertainty in safety assessment programs,known as“best estimate plus uncertainty(BEPU).”This approach aids in enhancing our comprehension of these programs and their further development and *** study concentrates on a third-generation pressurized water reactor equipped with advanced active and passive mitigation *** an Integrated Severe Accident Analysis Program(ISAA),numerical modeling and uncertainty analysis were conducted on severe accidents resulting from large break loss of coolant *** uncertainty parameters of the ISAA program were meticulously *** Wilks'formula,the developed uncertainty program code,SAUP,was employed to carry out Latin hypercube sampling,while ISAA was employed to execute batch *** analysis was then conducted on two figures of merit,namely hydrogen generation and the release of fission products within the pressure *** calculations revealed that hydrogen production and the fraction of fission product released exhibited a normal distribution,ranging from 182.784 to 330.664 kg and from 15.6 to 84.3%,*** ratio of hydrogen production to reactor thermal power fell within the range of 0.0578–0.105.A sensitivity analysis was performed for uncertain input parameters,revealing significant correlations between the failure temperature of the cladding oxide layer,maximum melt flow rate,size of the particulate debris,and porosity of the debris with both hydrogen generation and the release of fission products.

关键词： Gen-III PWR Severe accident mitigation Wilks’formula Hydrogen Fission products Uncertainty and sensitivity analysis

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Using a fretsaw in treating chronic penial incarceration:A case report

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World Journal of Clinical Cases 2022年第2期10卷 747-752页

作者： Yi Zhao Xiao-Qiang Xue Hou-Feng Huang Yi Xie zhi-Gang ji Xin-Rong Fan Department of Urology Peking Union Medical College HospitalBeijing 100730China

BACKGROUND Penial incarceration(PI)is a rare *** is usually caused by a foreign object which strangulates at the base of the *** may derive from pranks,sexual demand,mental disease,or intention to prohibit urinary ***,these situations are emergent and immediate treatments are *** of chronic PI are less reported,and their treating methods are yet to be *** SUMMARY We reported a case on treating a 73-year-old male who had PI with a metallic hoop for three *** multidisciplinary consultation,the operation was performed successfully with the help of a *** the chronic strangulation,the prognosis of the patient was *** the best of our knowledge,this case was rare and precious as it featured the longest strangulating time,which might enlighten the treating process of future PI ***,we have reviewed and summarized major published cases to encapsulate appropriate approaches when facing diverse strangulation *** The selection of surgical tools depends on the material of the strangulating objects,the availability of equipment,and the severity of the penial *** urination function may not be affected after three months of incarceration as in our case,whilst prudent preoperative measures and multidisciplinary evaluations are always *** using a fretsaw is comparatively slow,it is safe and feasible to treat metallic penial incarceration.

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Lymphatic metastasis and nm23H_1 genetic instability in Chinese colon cancer patients

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World Journal of Gastroenterology 2004年第19期10卷 2800-2804页

作者： zhi-HongSu ji-ChenaLi DepartmentofHistologyandEmbryol6gy ZhejiangUniversityMedicalCollegeHangzhou310031ZhejiangProvinceChina

AIM: To investigate the pathogenic mechanism of colon cancer at the molecular level and to elucidate the relationship between intercellular adhesion molecule-1 (ICAM-1) and nm23H1 genes and Chinese patients with colon ***: DNA was extracted from paraffin-embedded materials. Polymerase chain reaction-single s^and conformation polymorphism (PCR-SSCP) was used to analyze MSI and LOH. Expression of ICAM-1 was detected by Envision immuno-histochemistry. Experimental results were analyzed with Leica-Qwin computer imaging techniques and SPSS software of ***: ICAM-1 expression of lymphatic endothelium was negative in normal colon and posi0ve in colon cancer respectively. The number of lymphatics positive for ICAM-1 was gradually increased with degree of cancer invasion (P<0.01). In the group with metastasis of colon cancer, bhe number of lymphatics positive for ICAM-1 in lymph nodes was more than that in the group with no metastasis (P<0.01). The frequency of MSI, LOH and nm23H1 protein was 26.67%, 20.00% and 53.33% in colon cancer, respectively. In TNM staging, MSI (43.75%) and nm23H1 protein (81.25%) in stages I+II weredetected more easily than the corresponding indexes (MSI:7.14%, P<0.05 and nm23H,: 21.43%, P<0.01) in stages III+IV. By comparison, the frequency of LOH (35.71%) in stages III+IV was more than that of LOH (6.25%, P<0.05) in stages I+II. LOH exhibited a rising trend along with the Duke's staging, nm23H1 protein in the group of tubular adenocarcinoma (60.00%) was higher expressed than that in the group of mucoid adenocarcinoma (20.00%) (P<0.01),and exhibited a rising trend with the differentiation degrees of tubular adenocarcinoma, nm23H, protein in MSI positive group was higher expressed (75%) than that in MSI negative group (45.45%, P<0.05).CONCLUSION: The expression of ICAM-1 in lymphatic vessels is beneficial to the judgement of the invasion and metastasis ability of colon cancer and the anti-tumor immunity function,and shows an

关键词：淋巴腺癌 nm23H1 遗传学不稳定性中国结肠癌肿瘤基因多肽

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3D digital image microscope system-assisted vasovasostomy and vasoepididymostomy in rats

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Asian Journal of Andrology 2021年第4期23卷 396-399页

作者： Peng Li Na-Chuan Liu Er-Lei zhi Chen-Cheng Yao zhi-Liang Zhao zhi-Yong Yu Qi-Meng Li Yu-Hua Huang jie-Chang Ju Wen-Bin Huang Husanjan Rozi zhi-Yong ji San-Wei Guo Ru-Hui Tian Zheng Li Shanghai General Hospital Shanghai Jiao Tong University School of MedicineShanghai 200080China Gansu Provincial Hospital of Traditional Chinese Medicine Lanzhou 730050China Weifang Traditional Chinese Hospital Weifang 250200China The Third Affiliated Hospital of Wenzhou Medical University Wenzhou 325000China Zhengzhou Central Hospital Affiliated with Zhengzhou University Zhengzhou 450007China Wenzhou Integrated Traditional Chinese Wenzhou 325000China Kashgar District Second People's Hospital Kashgar 844000China Shanghai General Hospital of Nanjing Medical University Shanghai 200080China Shanghai Tenth People's Hospital Tongji UniversityShanghai 200072China

Optimal vision and ergonomics are essential factors contributing to the achievement of good results during *** three-dimensional(3D)digital image microscope system with a better 3D depth of field can release strain on the surgeon's neck and back,which can improve outcomes in *** report a randomized prospective study of vasoepididymostomy and vasovasostomy using a 3D digital image microscope system(3D-DIM)in rats.A total of 16 adult male rats were randomly divided into two groups of 8 each:the standard operating microscope(SOM)group and the 3D-DIM *** outcomes measured included the operative time,real-time postoperative mechanical patency,and anastomosis ***,a user-friendly microscope score was designed to evaluate the ergonomic design and equipment characteristics of the *** were no differences in operative time between the two *** real-time postoperative mechanical patency rates were 100.0%for both *** percentage of vasoepididymostomy anastomosis leakage was 16.7%in the SOM group and 25.0%in the 3D-DIM group;however,no vasovasostomy anastomosis leakage was found in either *** terms of the ergonomic design,the 3D-DIM group obtained better scores based on the surgeon's feelings;in terms of the equipment characteristics,the 3D-DIM group had lower scores for clarity and higher scores for flexibility and *** on our randomized prospective study in a rat model,we believe that the 3D-DIM can improve surgeon comfort without compromising outcomes in male infertility reconstructive microsurgery,so the 3D-DIM might be widely used in the future.

关键词： microsurgery three-dimensional digital image microscope system vasoepididymostomy vasovasostomy

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Clinical Characteristics and Outcome of Gleason Score 10 Prostate Cancer on Core Biopsy Treated by External Radiotherapy and Hormone Therapy

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Chinese Medical Sciences Journal 2015年第2期30卷 90-94页

作者： zhi-peng Mai Wei-gang Yan Han-zhong Li zhi-gang ji Fu-quan Zhang Ke Hu Yu Xiao Department of Urology Peking Union Medical College HospitalChinese Academy of Medical Sciences & Peking Union Medical College Department of Radiation Oncology Peking Union Medical College HospitalChinese Academy of Medical Sciences & Peking Union Medical College Department of Pathology Peking Union Medical College HospitalChinese Academy of Medical Sciences & Peking Union Medical College

Objective To evaluate the clinical characteristics and outcomes of patients with Gleason score 10 prostate cancer treated by external radiotherapy and hormone therapy. Methods From January 2003 to March 2014, 1832 patients with prostate cancer were treated, among which 9 patients(represented 0.49%) were identified as Gleason score 10 disease on prostate core biopsy without distant metastases when first diagnosed. All 9 patients were treated by whole pelvic external radiotherapy(The whole pelvic dose was 50.0 Gy and the boost dose ranged from 76.2 to 78.0 Gy) and long-term hormone therapy. We assessed the clinical characteristics, treatment outcomes and treatment toxicities. Survival curves were calculated using the Kaplan-Meier method. Results The median follow-up was 4.8 years. Six patients' pre-treatment prostate-specific antigen(PSA) levels were lower than 20.0 μg/L and three patients' pre-treatment PSA levels were higher than 70.0 μg/L. The median percentage of positive biopsy cores was 91%. Three, four and two cases were classified as T2 c, T3 a and T3 b stage, respectively. Three cases were assessed as N1 stage. The 5-year biochemical failure-free survival, distant metastasis-free survival, cancer specific survival and overall survival rates were 28.6%, 57.1%, 66.7% and 57.1%, respectively. Five patients experienced grade 1-2 acute gastrointestinal toxicities and six patients complained of grade 1-2 acute genitourinary toxicities. No bone fracture or cardiovascular disease was detected. Conclusions Gleason score 10 prostate cancer on core biopsy is usually combined with other high risk factors. The pre-treatment PSA levels lie in two extremes. Timely and active treatments are urgent needed because unfavourable oncological outcomes are often presented.

关键词： prostatic neoplasms biopsy neoplasm grading outcomes

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氢氧化铁胶体的制备及电泳实验的改进

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广州化工 2024年第3期52卷 173-176页

作者：孟祥珍姬志玉刘旭高鑫磊李静巢湖学院化学与材料工程学院安徽巢湖238000

在基础实验教学中,氢氧化铁胶体的制备及电泳实验,失败率居高不下。论文探讨了导致实验失败的可能因素,改进了胶体的纯化条件,优化了FeCl_3的用量,提高实验成功率。0.3或0.5 g FeCl_3固体制备约200 mL Fe(OH)_3胶体,在磁力搅拌下,用购... 详细信息

在基础实验教学中,氢氧化铁胶体的制备及电泳实验,失败率居高不下。论文探讨了导致实验失败的可能因素,改进了胶体的纯化条件,优化了FeCl_3的用量,提高实验成功率。0.3或0.5 g FeCl_3固体制备约200 mL Fe(OH)_3胶体,在磁力搅拌下,用购买的透析袋装130 mL胶体,50℃的蒸馏水透析,10 min换水,透析5次。透析后的胶体电泳现象明显,界面清晰,计算的ζ值与文献值更接近。

关键词：氢氧化铁胶体透析电泳

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