检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

以畜禽粪便与秸秆制取生物天然气碳减排分析

农业工程 2024年第12期14卷 73-78页

作者：张鹏姚晓春蔡伟伟王爽平扬曾宪伟张振洲余艳鸽中电建生态环境集团有限公司中节能衡准科技服务(北京)有限公司北京交通大学

根据生态环境部对碳减排项目的最新要求，对以畜禽粪便与秸秆为原料制取生物天然气项目的碳减排进行分析，该类项目可核算畜禽粪便收储与生物天然气替代两方面的碳减排量，并提出碳减排核算方法。选取河南省某生物天然气项目为典型案例... 详细信息

根据生态环境部对碳减排项目的最新要求，对以畜禽粪便与秸秆为原料制取生物天然气项目的碳减排进行分析，该类项目可核算畜禽粪便收储与生物天然气替代两方面的碳减排量，并提出碳减排核算方法。选取河南省某生物天然气项目为典型案例，测算项目的年碳减排量25 911 tCO2e，潜在的年减排效益259.11万元。分析项目运行过程中面临的困难，提出工作建议。

关键词：畜禽粪便秸秆生物天然气碳减排量经济效益

National Epidemiology and Evolutionary History of Four Hand, Foot and Mouth Disease-Related Enteroviruses in China from 2008 to 2016

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Virologica Sinica 2020年第1期35卷 21-33页

作者： Xuemin Fu zhenzhou Wan Yanpeng Li Yihong Hu Xia Jin Chiyu zhang Pathogen Discovery and Big Data Center CAS Key Laboratory of Molecular Virology and ImmunologyInstitut Pasteur of ShanghaiChinese Academy of SciencesUniversity of Chinese Academy of SciencesShanghai 200031China Medical Laboratory of Taizhou Fourth People’s Hospital Taizhou 225300China Viral Disease and Vaccine Translational Research Unit CAS Key Laboratory of Molecular Virology and ImmunologyInstitut Pasteur of ShanghaiChinese Academy of SciencesShanghai 200031China

Hand, foot and mouth disease(HFMD) is a major public health concern in China. The most predominant enteroviruses that cause HFMD have traditionally been attributed to enterovirus A71(EVA71) and coxsackievirus A16(CVA16). Since its first large outbreak in 2008, the dominant HFMD pathogens are constantly changing. In 2013 and 2015, CVA6 exceeded both EVA71 and CVA16 to become the leading cause of HFMD in some provinces. However, there still lacks a comprehensive overview on the molecular epidemiology and evolution of HFMD-related enteroviruses at the national level. In this study, we performed systematic epidemiological analyses of HFMD-related enteroviruses using the data of 64 published papers that met the inclusion criteria, and conducted phylogenetic analyses based on 12,080 partial VP1 sequences identified in China before 31 st June 2018. We found that EVA71 prevalence has decreased sharply but other enteroviruses have increased rapidly from 2008 to 2016 and that one subtype of each enterovirus is represented during the epidemic. In addition, four genotypes EVA71_C4, CVA16_B1, CVA6_D and CVA10_C are the most predominant enterovirus strains and collectively they cause over 90% of all HFMD cases in China according to the phylogenetic trees using representative partial VP1 sequences. These four major enterovirus genotypes have different geographical distributions, and they may cocirculate with other genotypes and serotypes. These results suggest that more molecular epidemiological studies should be performed on several enteroviruses simultaneously, and such information should have implications for virological surveillance, disease management, vaccine development and policy-making on the prevention and control of HFMD.

关键词： Enterovirus Hand,foot and mouth disease(HFMD) Molecular epidemiology Evolution Genotype

在线全文

学校读者我要写书评

暂无评论

城市管道车载清洗装置

清洗世界 2016年第2期32卷 39-41页

作者：张振洲马洪发张明松韩龙刘锋韩乃波朱程皓沈阳仪表科学研究院有限公司辽宁沈阳110043

城市管道包括雨水、污水、给水、自来水等管道,作为城市主要的市政设施,保持管道畅通无阻是非常必要的。在经过一定时间使用之后,管道内部会结垢、变窄或堵塞,必须对这些管道进行清洗和疏通。介绍一种城市车载管道清洗设备,可用于城市... 详细信息

城市管道包括雨水、污水、给水、自来水等管道,作为城市主要的市政设施,保持管道畅通无阻是非常必要的。在经过一定时间使用之后,管道内部会结垢、变窄或堵塞,必须对这些管道进行清洗和疏通。介绍一种城市车载管道清洗设备,可用于城市市政工程大直径管道清洗和疏通。

关键词：城市管道清洗车载

Empirical modeling of normal/cyclo-alkanes pyrolysis to produce light olefins

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2022年第2期35卷 389-398页

作者： Xu Hou Bochong Chen zhenzhou Ma Jintao zhang Yuanhang Ning Donghe zhang Liu Zhao Enxian Yuan Tingting Cui School of Chemical Engineering Changchun University of TechnologyChangchun 130012China Advanced Institute of Materials Science Changchun University of TechnologyChangchun 130012China School of Chemistry and Chemical Engineering Yangzhou UniversityYangzhou 225009China Department of Chemistry Tsinghua UniversityBeijing 100084China

Due to the complexity of feedstock,it is challenging to build a general model for light olefins *** work was intended to simulate the formation of ethylene,propene and 1,3-butadiene in alkanes pyrolysis by referring the effects of normal/***,the pyrolysis of n-pentane,n-hexane,n-heptane,n-octane,n-nonane,n-decane,cyclohexane,methylcyclohexane,n-hexane and cyclohexane mixtures,and n-heptane and methylcyclohexane mixtures were carried out at 650–800℃,and a particular attention was paid to the measurement of ethylene,propene and 1,***,pseudo-first order kinetics was taken to characterize the pyrolysis process,and the effects of feedstock composition were *** was found that chain length and cyclo-alkane content can be qualitatively and quantitively represented by carbon atom number and pseudo-cyclohexane content,which made a significant difference on light olefins ***,the inverse proportional/quadratic function,linear function and exponential function were proposed to simulate the effects of chain length,cycloalkane content and reaction temperature on light olefins formation,*** the obtained empirical model well reproduced feedstock conversion,ethylene yield and propene yield in normal/cycloalkanes pyrolysis,it exhibited limitations in simulating 1,3-butadiene ***,the accuracy and flexibility of the present model was validated by predicting light olefins formation in the pyrolysis of multiple hydrocarbon *** prediction data well agreed with the experiment data for feedstock conversion,ethylene yield and propene yield,and overall characterized the changing trend of 1,3-butadiene yield along with reaction temperature,indicating that the present model could basically reflect light olefins production in the pyrolysis process even for complex feedstock.

关键词： Empirical model Normal-alkane Cyclo-alkane Pyrolysis Light olefins

A new perspective of triptolide-associated hepatotoxicity:the relevance of NF-κB and NF-κB-mediated cellular FLICE-inhibitory protein

在线全文

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica B 2020年第5期10卷 861-877页

作者： Ziqiao Yuan Zihang Yuan Muhammad Hasnat Haoran zhang Peishi Liang Lixin Sun zhenzhou Jiang Luyong zhang Jiangsu Key Laboratory of Drug Screening China Pharmaceutical UniversityNanjing 210009China Center for Drug Research and Development Guangdong Pharmaceutical UniversityGuangzhou 510006China Jiangsu Center for Pharmacodynamics Research and Evaluation China Pharmaceutical UniversityNanjing 210009China Key Laboratory of Drug Quality Control and Pharmacovigilance(China Pharmaceutical University) Ministry of EducationNanjing 210009China State Key Laboratory of Natural Medicines China Pharmaceutical UniversityNanjing 210009China Institute of Pharmaceutical Sciences University of Veterinary and Animal SciencesLahore 54000Pakistan College of Traditional Chinese Medicine Guangdong Pharmaceutical UniversityGuangzhou 510006China

Previously,we proposed a new perspective of triptolide(TP)-associated hepatotoxicity:liver hypersensitivity upon lipopolysaccharide(LPS)***,the mechanisms for TP/LPSinduced hepatotoxicity remained *** present study aimed to clarify the role of LPS in TP/LPS-induced hepatotoxicity and the mechanism by which TP induces liver hypersensitivity upon LPS ***-αinhibitor,etanercept,was injected intraperitoneally into mice to investigate whether induction of TNF-αby LPS participated in the liver injury induced by TP/LPS *** and hepatocytes pretreated with TP were stimulated with recombinant TNF-αto assess the function of TNF-αin TP/LPS ***,time-dependent MF-κB activation and NF-κB-mediated pro-survival signals were measured in vivo and in ***,overexpression of cellular FLICEinhibitory protein(FLIP),the most potent NF-κB-mediated pro-survival protein,was measured in vivo and in vitro to assess its function in TP/LPS-induced *** counteracted the toxic reactions induced by TP/***-treatment sensitized mice and hepatocytes to TNF-α,revealing the role of TNF-αin TP/LPS-induced *** studies revealed that TP inhibited NF-κB dependent pro-survival signals,especially FLIP,induced by LPS/TNF-α.Moreover,overexpression of FLIP alleviated TP/LPS-induced hepatotoxicity in vivo and TP/TNF-α-induced apoptosis in *** and hepatocytes treated with TP were sensitive to TNF-α,which was released from LPS-stimulated immune *** and other results show that the TP-induced inhibition of NF-κB-dependent transcriptional activity and FLIP production are responsible for liver hypersensitivity.

关键词： Triptolide LPS TNF-x NF-KB FLIP

在线全文

学校读者我要写书评

暂无评论

成人急性髓系白血病治疗现状及新药研究进展

药学与临床研究 2018年第4期26卷 281-286页

作者：吴蒙莹舒婷刘佳江振洲张陆勇中国药科大学江苏省新药筛选重点实验室南京210009 中国药科大学药物质量与安全预警教育部重点实验室南京210009

急性髓系白血病(Acute myeloid leukemia,AML)是一类高度异质性疾病,过去常规诱导化疗和各类支持治疗为主,但随着二代测序等技术应用以来,AML药物迅速发展。本文从细胞毒药物、小分子靶向药物以及免疫靶向药物等方面,系统概述AML的致病... 详细信息

急性髓系白血病(Acute myeloid leukemia,AML)是一类高度异质性疾病,过去常规诱导化疗和各类支持治疗为主,但随着二代测序等技术应用以来,AML药物迅速发展。本文从细胞毒药物、小分子靶向药物以及免疫靶向药物等方面,系统概述AML的致病机制,以及临床研究中较为前沿的各类新型药物(如FLT3抑制剂Midostaurin、IDH抑制剂AG-221和CPX-351等)的研究进展,旨在为AML的新药研发提供参考。

关键词：急性髓系白血病靶向治疗新型药物

在线全文

学校读者我要写书评

暂无评论

间接空冷凝汽器喷雾降温过程分析与应用

清洗世界 2015年第4期31卷 1-4,8页

作者：孙震刘锋马洪发张振洲韩乃波余菁华沈阳仪表科学研究院有限公司辽宁沈阳110043

为了适应在夏季高温环境下,间接空冷机组带较高负荷发电,可釆用喷雾降温的方法作为尖峰度夏措施。本文介绍了间接空冷机组喷雾降温过程的工作原理,分析了雾滴在空气入口处进行湿热交换的过程和影响喷雾降温效果的主要因素。以国产某单台... 详细信息

为了适应在夏季高温环境下,间接空冷机组带较高负荷发电,可釆用喷雾降温的方法作为尖峰度夏措施。本文介绍了间接空冷机组喷雾降温过程的工作原理,分析了雾滴在空气入口处进行湿热交换的过程和影响喷雾降温效果的主要因素。以国产某单台330MW间接空冷机组为例,为其设计了一套喷雾降温系统,经使用,冷却降温效果显著。

关键词：间接空冷空冷凝汽器湿热交换喷淋降温

不同钾肥品种及用量对马铃薯产量和品质的影响

在线全文

学校读者我要写书评

暂无评论

中国马铃薯 2013年第3期27卷 158-161页

作者：周芳张振洲贾景丽刘兆财贾立君杜江本溪市马铃薯研究所辽宁本溪117000

以‘荷兰15’为试验品种,采用随机区组设计进行田间试验,研究不同钾肥品种(氯化钾和硫酸钾)及其用量对马铃薯产量和品质的影响,以期指导马铃薯钾肥的施用。结果表明,不同钾肥品种均提高了马铃薯的产量,降低了还原糖含量。与施用硫酸钾相... 详细信息

以‘荷兰15’为试验品种,采用随机区组设计进行田间试验,研究不同钾肥品种(氯化钾和硫酸钾)及其用量对马铃薯产量和品质的影响,以期指导马铃薯钾肥的施用。结果表明,不同钾肥品种均提高了马铃薯的产量,降低了还原糖含量。与施用硫酸钾相比,施用氯化钾后,单薯重提高,产量增加幅度较大。若施用氯化钾,用量以18 kg/667m2(K2O)为佳;若施用硫酸钾,用量以21 kg/667m(2K2O)为佳。以优质为目的,钾肥用量低时,氯化钾为优,钾肥用量高时,硫酸钾为优。

关键词：马铃薯钾肥产量品质

Grid-Based Path Planner Using Multivariant Optimization Algorithm

在线全文

学校读者我要写书评

暂无评论

Journal of Harbin Institute of Technology(New Series) 2015年第5期22卷 89-96页

作者： Baolei Li Danjv Lv Xinling Shi zhenzhou An Yufeng zhang Jianhua Chen School of Information Science and Engineering Yunnan University Oil Equipment Intelligent Control Engineering Laboratory of Henan Provice Physics & Electronic Engineering CollegeNanyang Normal University School of Information Technology and Engineering Yuxi Normal University

To solve the shortest path planning problems on grid-based map efficiently,a novel heuristic path planning approach based on an intelligent swarm optimization method called Multivariant Optimization Algorithm( MOA) and a modified indirect encoding scheme are proposed. In MOA,the solution space is iteratively searched through global exploration and local exploitation by intelligent searching individuals,who are named as atoms. MOA is employed to locate the shortest path through iterations of global path planning and local path refinements in the proposed path planning approach. In each iteration,a group of global atoms are employed to perform the global path planning aiming at finding some candidate paths rapidly and then a group of local atoms are allotted to each candidate path for refinement. Further,the traditional indirect encoding scheme is modified to reduce the possibility of constructing an infeasible path from an array. Comparative experiments against two other frequently use intelligent optimization approaches: Genetic Algorithm( GA) and Particle Swarm Optimization( PSO) are conducted on benchmark test problems of varying complexity to evaluate the performance of MOA. The results demonstrate that MOA outperforms GA and PSO in terms of optimality indicated by the length of the located path.

关键词： multivariant optimization algorithm shortest path planning heuristic search grid map optimality of algorithm