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Penchang Village's Two-Fold Advancement

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China's Tibet 2023年第6期34卷 22-25页

作者： zhao zhenyu(文/图) 不详

Panam County of Shigatse City in the Xizang Autonomous Region enjoys the honor of being known as the"hometown of vegetables and fruits"on the *** the 1990s,with the full support of Shandong Province,it has entered the... 详细信息

关键词： Village Advance Shandong

Geoelectric Structures Imaging in the Jarud Basin through Magnetotelluric Sounding Preliminary Results

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Patients with SARS-CoV-2 and HBV coinfection are at risk of greater liver injury

工程地球物理学报 2014年第3期 311-318页

作者： zhao Weijun zhao zhenyu Jia Liguo

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Genes & Diseases 2021年第4期8卷 484-492页

作者： Yong Lin Jun Yuan Quanxin Long Jieli Hu Haijun Deng zhenyu zhao Juan Chen Mengji Lu Ailong Huang Key Laboratory of Molecular Biology of Infectious Diseases(Chinese Ministry of Education) Chongqing Medical UniversityChongqing400016PR China School of Public Health and Management Chongqing Medical UniversityChongqing400016PR China Institute for Virology University Hospital of EssenUniversity of Duisburg-EssenEssen45122Germany

To date,it remains unclear if severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)co-infection exacerbates liver injury in patients with chronic hepatitis B virus(HBV)*** this study,we present a retrospective study of 133 hospitalized confirmed mild coronavirus disease 2019(COVID-19)cases,including 116 patients with COVID-19 with negative serum hepatitis B antigen and 17 HBV inactive carriers with *** found that there were no significant differences for the discharge rate or duration of hospitalization be-tween the two ***,inactive HBV carriers with SARS-CoV-2 co-infection are at a higher risk of abnormal liver function *** enhanced liver injury induced by SARS-CoV-2 and HBV co-infection was identified as the hepatocyte type rather than the cholangiocyte ***,the inflammatory response,including abnormal lactate dehydrogenase,D-dimer and interleukin-6 production,may contribute to this injury following SARS-CoV-2 ***,SARS-CoV-2 and HBV co-infection exacerbates liver function of the pa-tients with COVID-19.

关键词： Abnormal liver function COVID-19 HBV Inactive HBV carriers Liver injury SARS-CoV-2

Applications of Cerebrospinal Fluid Circulating Tumor DNA in the Diagnosis and Prognosis of Gliomas

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Applications of Cerebrospinal Fluid Circulating Tumor DNA in...

Determination of an Unknown Source in the Heat Equation by the Method of Tikhonov Regularization in Hilbert Scales

2017年中国肿瘤标志物学术大会暨第十一届肿瘤标志物青年科学家论坛

作者： zhenyu zhao Xinguang Yu Department of Neurosurgery PLA General Hospital

Objective: The 2016 WHO CNS tumor classification provided revised molecular biomarkers as diagnostic criteria. However, conventional biopsy suffers from space and time heterogeneity. Liquid biopsy is the least invasive and easily repeated biopsy method, and can reveal more comprehensive tumor features. Methods: Cerebrospinal fluid(CSF) and matching tumor tissue were obtained from patients undergoing resection of gliomas. Combined with clinical data, the differences among the patients with respect to primary recurrence, subtype of gliomas, tumor grade, and prognosis were analyzed in this ***: CSF ctDNA mutation has high concordance rate with tumor tissue. 7 CSF circulating tumor DNA(ctDNA) mutations, including IDH1, IDH2 were reduced significantly after surgery. CtDNA mutations of CDKN2 A, PTEN were detected commonly and significantly in the CSF of patients with recurrent gliomas. According to the 2016 WHO CNS tumor classification, 9 mutations were detected in the CSF of patients with astrocytoma, 1 mutation was detected more commonly in patients with oligodendroglioma, while PTEN mutations were detected commonly in glioblastoma multiforme. 3 mutations were detected in the low-grade glioma group, whereas 5 mutations including PTEN were detected more commonly in the high-grade group. CtDNA mutations of IDH1, PTPN11 were detected frequently in patients with good prognosis, whereas the patients with poor prognosis usually harbored CSF ctDNA PTEN, RB1 mutations. Conclusions: CSF ctDNA analysis could be applied as a supplementary method in pathological diagnosis. CSF ctDNA mutation of PTEN can suggest the malignant degree and possibility of recurrence, prognosis in gliomas. CSF ctDNA could be applied for preoperative diagnosis, surgical planning, prediction of postoperative recurrence and prognosis, and as a noninvasive assessment of response and resistance.

关键词： ctDNA CSF Glioma Liquid Biopsy Prognosis

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Journal of Applied Mathematics and Physics 2014年第2期2卷 10-17页

作者： zhenyu zhao Ou Xie Zehong Meng Lei You College of Science Guangdong Ocean University Zhanjiang China School of Mathematics and Statistics Zhejiang University of Finance and Economics Hangzhou China

In this paper, we consider the problem for determining an unknown source in the heat equation. The Tikhonov regularization method in Hilbert scales is presented to deal with ill-posedness of the problem and error estimates are obtained with a posteriori choice rule to find the regularization parameter. The smoothness parameter and the a priori bound of exact solution are not needed for the choice rule. Numerical tests show that the proposed method is effective and stable.

关键词： Ill-Posed Problem Unknown Source Heat Equation Regularization Method Discrepancy Principle in Hilbert Scales

Dynamic response of ultralight all-metallic sandwich panel with 3D tube cellular core to shallow-buried explosives

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Science China(Technological Sciences) 2021年第7期64卷 1371-1388页

作者： ZHANG DuJiang zhao Zhen Yu DU ShaoFeng CHEN WeiJie YANG Fan NI ChangYe YANG ZhiKun LU TianJian State Key Laboratory of Mechanics and Control of Mechanical Structures Nanjing University of Aeronautics and AstronauticsNanjing210016China MIIT Key Laboratory of Multifunctional Lightweight Materials and Structures(MLMS) Nanjing University of Aeronautics and AstronauticsNanjing210016China State Key Laboratory of Smart Manufacturing for Special Vehicles and Transmission System Baotou014030China State Key Laboratory for Strength and Vibration of Mechanical Structures Xi’an Jiaotong UniversityXi’an710049China

The underbody of a vehicle system, either military or civil, is typically made of a relatively thin metallic plate, thus vulnerable to mine blast attacks. To improve the blast resistance, a multitude of protective structures have been proposed as attachments to the thin plate. In the present study, a novel ultralight all-metallic sandwich panel with three-dimensional(3D) tube cellular cores mounted to the vehicle underbody was envisioned as such a protective system. A metallic substrate(mimicking vehicle bottom)was placed above the proposed sandwich panel to construct a sandwich-substrate combinative structure. A series of sandwich panels having 3D tube cellular cores were fabricated via argon protected welding and laser welding. Mechanical responses of the combinative structure subjected to the denotation of 6 kg TNT explosives shallow-buried in dry sand were experimentally measured. Full numerical simulations with the method of finite elements(FE) were subsequently carried out to explore the physical mechanisms underlying the observed dynamic performance and quantify the effects of key geometrical parameters and connection conditions of the protective system. The performance of the proposed sandwich panel under shallow-buried explosives was also compared with competing sandwich constructions having equal mass. Finally, a preliminary optimal design of the 3D tube cellular core was carried out.

关键词： shallow-buried explosive sand blast test 3D tube cellular core sandwich panel numerical simulation

A telomere-to-telomere genome assembly of Hongyingzi,a sorghum cultivar used for Chinese Baijiu production

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The Crop Journal 2024年第2期12卷 635-640页

作者： Yanqing Ding Yilin Wang Jianxia Xu Feng Jiang Wenzhen Li Qiaoling Zhang Longping Yang zhenyu zhao Bin Cheng Ning Cao Xu Gao Xin Zhang Guihua Zou Fan Yang Liyi Zhang Guizhou Institute of Upland Crops Guizhou Academy of Agricultural SciencesGuiyang 550006GuizhouChina Kweichow Moutai Co. Ltd.Maotai TownRenhuai 564501GuizhouChina Kweichow Moutai Distillery(Group)Hongyingzi Agricultural Technology Development Co. Ltd.Maotai TownRenhuai 564501GuizhouChina Wuhan GrandOmics Biosciences Co. Ltd.Grandomics BiosciencesWuhan 430000HubeiChina Institute of Crop and Nuclear Technology Utilization Zhejiang Academy of Agricultural SciencesZhejiang

Sorghum(Sorghum bicolor(L.)Moench)is a world cereal crop used in China for producing Baijiu,a distilled *** report a telomere-to-telomere genome assembly of the Baijiu cultivar Hongyingzi,HYZ-T2T,using ultralong *** 10 chromosome pairs contained 33,462 genes,of which 93%were functionally *** 20 telomeres and 10 centromeric regions on the HYZ-T2T chromosomes were predicted and two consecutive large inversions on chromosome 2 were characterized.A 65-gene reconstruction of the metabolic pathway of tannins,the flavor substances in Baijiu,was performed and may advance the breeding of sorghum cultivars for Baijiu production.

关键词： Sorghum Telomere-to-telomere assembly Hongyingzi(HYZ) Chinese Baijiu-making cultivar

Quantitative Prediction of Concentrated Regions of Large and Superlarge Deposits in China

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Journal of China University of Geosciences 2003年第3期14卷 245-249页

作者： Wang Shicheng zhao zhenyu Wang Yutian Mineral Resources Institute of Comprehensive Information Prediction, Jilin University, Changchun 130026 Mineral Resources Institute of Comprehensive Information Prediction Jilin University Changchun 130026

Identification and quantitative prediction of large and superlarge mineral deposits of solid mineral resources using the mineral resource prediction theory and method with comprehensive information is carried out nationwide in China at a scale of 1∶5 000 000. Using deposit concentrated regions as the model units and concentrated mineralization anomaly regions as prediction units, the prediction is performed on GIS platform. The technical route and research method of locating large and superlarge mineral deposits and principle of compiling attribute table of independent variables and functional variables are proposed. Upon methodology study, the qualitative locating and quantitative predicting mineral deposits are carried out with quantitative theory Ⅲ and characteristic analysis, respectively, and the advantage and disadvantage of two methods are discussed. This research is significant for mineral resource prediction in ten provinces of western China.

关键词： mineral deposit prediction quantitative prediction large ore deposits concentrated ore deposit region variable attribute table ore deposits in China

Bending Stiffness of Concrete-Filled Steel Tube and Its Influence on Concrete Placement Timing of Composite Beam-String Structure

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Structural Durability & Health Monitoring 2025年第1期19卷 55-75页

作者： zhenyu Zhang Quan Jin Haitao Zhang zhao Liu Yuyang Wu Longfei Zhang Renzhang Yan CCCC Third Highway Engineering Co. Ltd.Beijing101300China School of Civil Engineering Chongqing Jiaotong UniversityChongqing400074China

When the upper chord beam of the beam-string structure(BSS)is made of concrete-filled steel tube(CFST),its overall stiffness will change greatly with the construction of concrete placement,which will have an impact on the design of the tensioning plans and selection of control measures for the *** order to accurately obtain the bending stiffness of CFST beam and clarify its impact on the mechanical properties of composite BSS during construction,the influence of some factors such as height-width ratio,wall thickness of steel tube,elasticity modulus of concrete,and friction coefficient on the bending stiffness are analyzed parametrically by the numerical simulation technology based on an actual *** calculation formula of the equivalent bending stiffness of CFST is also established through mathematical statistical ***,the equivalent bending stiffness is introduced into the construction and use stages of the composite BSS,respectively,and the mechanical properties such as prestress-tensioning control value,structural deformation,and internal force of key members are comparatively analyzed when adopting two different construction ***,the optimal construction plan of concrete placement first and then prestress-tensioning is proposed.

关键词： Concrete panels freeze-thaw damage compression-shear crack tension-shear crack