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Can patients with mild non-neoplastic lesions diagnosed at baseline screening be safely exempt from surveillance: evidence from multicenter community-based cohorts

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Science China(Life Sciences) 2025年第1期68卷 263-271页

作者： Siyi He Zhiyi Zhang Guohui Song zhenhai wang Chunyun Dai Shipeng Yan Kun Jiang Bingbing Song He Li Maomao Cao Dianqin Sun Fan Yang Xinxin Yan Shaoli Zhang Yi Teng Qianru Li Changfa Xia Wanqing Chen Office of Cancer Screening National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Department of Gastroenterology Gansu Wuwei Tumor HospitalWuwei 730000China Cixian Cancer Institute Handan 056500China Linzhou Cancer Hospital Linzhou 456550China Center for Disease Control and Prevention of Sheyang County Yancheng 224499China Department of Cancer Prevention and Control Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of MedicineCentral South UniversityChangsha 410029China Luoshan Center for Disease Control and Prevention Xinyang 464299China Office for Cancer Control and Research Affiliated Cancer Hospital of Harbin Medical UniversityHarbin 150081China

Surveillance recommendations for gastric cancer(GC)in current guidelines focused on advanced precancerous lesions and were based on precise diagnosis of severity/extent of baseline *** aimed to develop a less endoscopy-related equipment-dependent risk-stratification tool,and assessed whether mild-precursor-lesion patients can be safely exempt from *** the multicenter communitybased cohort,75,051 participants receiving baseline endoscopy were enrolled during 2015–2017 and followed-up until *** incidence rates(CIRs)of GC for precancerous-conditions were calculated by Kaplan-Meier method and compared by Log-rank *** Cox regression models were used to detect potential factors for progression towards GC.A risk score was calculated as counts of selected *** independent cohort,including 26,586 participants was used for external *** a median follow-up of 6.25 years,CIRs of GC were 0.302%,0.436%,and 4.756%for normal group,non-neoplastic(atrophic gastritis/intestinal metaplasia)and neoplastic lesions(low-grade/high-grade dysplasia),respectively(Ptrend<0.001).Four predictors,including male,≥60 years,smoking,and limited vegetable consumption,were selected for ***-risk patients(≥3 risk factors)with non-neoplastic lesions showed higher GC risks(adjusted HR=7.73,95%CI:4.29–13.92),and their four-year CIR reached the one-year CIR of neoplastic *** categorizing non-neoplastic lesions by histological grade,both patients with moderate-to-severe lesions(aHR=3.07,95%CI:1.67–5.64)and high-risk patients with mild lesions(aHR=7.29,95%CI:3.58–14.86)showed higher *** trends were observed in validation ***-risk mild-precursor-lesion patients should receive surveillance within 3–5 years after baseline *** study provides evidence on supplementing current guideline recommendations.

关键词： stomach neoplasms precancerous conditions cancer screening cumulative incidence risk stratification

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Multivalent manganese oxides with high electrocatalytic activity for oxygen reduction reaction

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Frontiers of Chemical Science and Engineering 2018年第4期12卷 790-797页

作者： Xiangfeng Peng zhenhai wang Zhao wang Yunxiang Pan School of Chemical Engineering and Technology State Key Laboratory of Chemical EngineeringTianjin UniversityTianjin 300350China School of Chemistry and Chemical Engineering Hefei University of TechnologyHefei 230009China

A noble-metal-free catalyst based on both Mn3O4 and MnO was prepared by using the dielectric barrier discharge technique at moderate temperature. The prepared catalyst shows a higher electrocatalytic activity towards the oxygen reduction reaction than the catalyst prepared by using the traditional calcination process. The enhanced activity could be due to the coexistence of manganese ions with different valences, the higher oxygen adsorption capacity, and the suppressed aggregation of the catalyst nanoparticles at moderate temperature. The present work would open a new way to prepare low-cost and noble-metal-free catalysts at moderate temperature for more efficient electrocatalysis.

关键词： oxygen reduction reaction manganese oxides mixed valences of manganese oxygen adsorption dielectric barrier discharge

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Effect of hygrothermal aging on moisture diffusion and tensile behavior of CFRP composite laminates

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Chinese Journal of Aeronautics 2023年第3期36卷 382-392页

作者： Yong DU Yu’e MA Wenbo SUN zhenhai wang School of Aeronautics Northwestern Polytechnical UniversityXi’an 710072China School of Mathematics and Statistics Northwestern Polytechnical UniversityXi’an 710129China

Carbon Fiber Reinforced Polymer(CFRP)composites are widely used in aircraft structures,because of their superior mechanical and lightweight *** composites are often exposed to hygrothermal environments in *** and moisture can affect the material properties of *** order to make clear the moisture diffusion behavior and the properties degradation of composites,the TG800/E207 composite laminates with four stacking sequences[0]16,[90]16,[±45]4s,and[(+45/0/0/-45)s]sare designed and *** absorption tests are carried out at 80℃,90%*** is shown that the moisture absorption curves of composite laminates present a three-stage.A modified Fickian model was proposed to capture the diffusion behavior of TG800/E207 composite *** relationships among the non-Fickian parameters,the environmental parameters and the stacking sequences of CFRP were correlated and *** showed that the modified Fickian curve is sensitive to the diffusivity of Stage Ⅰ and Stage Ⅱ.Compared with unaged specimens,the maximum tensile stress for[0]16,[90]16,[±45]4s,and[(+45/0/0/-45)s]sdecreased by 14.94%,28.15%,11.96%,and 26.36%,*** strains at failure for[0]16,[90]16,[±45]4s,and[(+45/0/0/-45)s]sdecreased by 55.38%,62.65%,46.41%,and31.71%,*** elastic modulus for[0]16,[90]16,[±45]4s,and[(+45/0/0/-45)s]sincreased by 90.93%,94.57%,49.22%,and 8.22%,respectively.[90]16sample has the minimum saturated moisture content and the maximum strength degeneration.

关键词： CFRP Hygrothermal aging Moisture diffusion Stacking sequence Tensile behavior

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Enhanced degradation of tetracycline by gas-liquid discharge plasma coupled with g-C_(3)N_(4)/TiO_(2)

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Plasma Science and Technology 2024年第9期26卷 69-78页

作者： zhenhai wang Zikai ZHOU Sen wang Zhi FANG College of Electrical Engineering and Control Science Nanjing Tech UniversityNanjing 211816People’s Republic of China

Plasma-catalysis is considered as one of the most promising technologies for antibiotic degradation in *** the plasma-catalytic system,one of the factors affecting the degradation effect is the performance of the photocatalyst,which is usually restricted by the rapid recombination of electrons and holes as well as narrow light absorption *** this research,a photocatalyst g-C_(3)N_(4)/TiO_(2) was prepared and coupled with gas-liquid discharge(GLD)to degrade tetracycline(TC).The performance was examined,and the degradation pathways and mechanisms were *** show that a 90%degradation rate is achieved in the GLD with g-C_(3)N_(4)/TiO_(2) over a 10 min *** the pulse voltage is conducive to increasing the degradation rate,whereas the addition of excessive g-C_(3)N_(4)/TiO_(2) tends to precipitate agglomerates,resulting in a poor degradation *** redox properties of the g-C_(3)N_(4)/TiO_(2) surface promote the generation of oxidizing active species(H2O2,O3)in *** quenching experiments showed that·OH,hole(h^(+)),play important roles in the TC degradation by the discharge with g-C_(3)N_(4)/TiO_(2).Two potential degradation pathways were proposed based on the *** toxicity of tetracycline was reduced by treatment in the ***,the g-C_(3)N_(4)/TiO_(2) composites exhibited excellent recoverability and stability.

关键词： gas-liquid discharge plasma-catalysis g-C_(3)N_(4)/TiO_(2) TC degradation

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Low impedance nature of 12 acupoints on the limbs,and the unexpected dependence on limb angle

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Journal of Traditional Chinese Medicine 2018年第2期38卷 287-298页

作者： Xu Jingjing Yang Fan Han Danhong wang zhenhai Hong Yuankai Han Hongbin Xu Shengyong Key Laboratory for the Physics & Chemistry of Nanodevices and Department of ElectronicsPeking University Department of Biophysics School of Basic Medical SciencesPeking University Department of Radiology Peking University Third HospitalPeking University

OBJECTIVE: To better understand the working mechanism of acupuncture, we investigated the skin electrical impedance distribution around acupoints, and the impedance changes at 12 original acupoints bilaterally after bending the ***: We measured the skin electrical impedance in three study subjects in the frequency range of 40 to 10 k Hz using the four-electrode method with a sharp probe and a large reference electrode.A measurement matrix of 7 mm × 7 mm with spacing of 2.0(or 3.0) mm was measured to obtain 2 D impedance mapping of acupoints. The impedance spectra of 12 original acupoints were measured at the 0° position and the 90° ***: The electrical impedance of some acupoints, such as Yangchi(TE 4), was 16 times lower than that of the surrounding area, showing a recognizable small central area of low impedance with a diameter of less than 4 mm. In contrast, other acupoints, such as Laogong(PC 8), had an electrical impedance that was not significantly different from that of the surrounding area. When the limb was bent from a straight position(0o) to a vertical position(90o), the electrical impedance of the 12 original acupoints showed varied trends, either increasing or decreasing by a factor of up to ten times, or remaining at the same ***: Not all acupoints tested show the property of low impedance, which might be related to the varied depth of the openings of superficial collaterals. The unexpected dependence of acupoint impedance on limb angle is a novel discovery, which implies that the channel paths are located in interstitial structures in the limbs. It might be possible to determine an optimized limb position for each particular acupuncture treatment in clinical practice.

关键词： Channel Acupoint Superficial collater-als Electric impedance Limb

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采用FDDs实现FPRM电路延时和面积优化

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西安电子科技大学学报 2013年第1期40卷 135-140页

作者：汪鹏君王振海宁波大学电路与系统研究所浙江宁波315211 复旦大学专用集成电路与系统国家重点实验室上海201203

Functional Decision Diagrams(FDDs)是Reed-Muller(RM)展开式的一种图形表达方式,其变量顺序和RM展开式极性共同决定对应电路的延时和面积.通过对FDDs和固定极性RM(FPRM)展开式的研究,提出采用FDDs的FPRM电路延时和面积优化算法.首先... 详细信息

Functional Decision Diagrams(FDDs)是Reed-Muller(RM)展开式的一种图形表达方式,其变量顺序和RM展开式极性共同决定对应电路的延时和面积.通过对FDDs和固定极性RM(FPRM)展开式的研究,提出采用FDDs的FPRM电路延时和面积优化算法.首先根据固定极性特点,利用FDDs建立FPRM电路延时估计模型;然后结合延时估计模型、列表技术和FDDs变量顺序搜索策略,按电路延时和面积对中小规模和大规模电路进行最佳极性和变量顺序搜索;最后对PLA格式的MCNC Benchmark电路进行测试,结果表明该算法对延时和面积的优化效果显著.

关键词：电路综合 FPRM FDDs 延时和面积优化

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混合极性列表技术及其在MPRM电路面积优化中的应用

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计算机辅助设计与图形学学报 2011年第3期23卷 527-533页

作者：李辉汪鹏君王振海宁波大学电路与系统研究所宁波315211

通过对AND/XOR展开式和函数转换的研究,提出多输出混合极性Reed-Muller(MPRM)表达式列表技术.根据Reed-Muller可编程逻辑阵列(RMPLA)的映射方法以及电路结构建立MPRM电路面积估计模型;在此基础上,结合列表技术和面积估计模型,沿非循环... 详细信息

通过对AND/XOR展开式和函数转换的研究,提出多输出混合极性Reed-Muller(MPRM)表达式列表技术.根据Reed-Muller可编程逻辑阵列(RMPLA)的映射方法以及电路结构建立MPRM电路面积估计模型;在此基础上,结合列表技术和面积估计模型,沿非循环格雷码极性遍历路径进行MPRM电路面积最佳极性搜索,得到面积最优的MPRM电路.通过对19个MCNC和ISCAS基准电路进行测试的结果表明:与Boolean电路和固定极性Reed-Muller(FPRM)电路相比,MPRM电路面积平均减少73.5%和51.8%.

关键词：混合极性Reed-Muller 列表技术面积优化穷尽搜索

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品牌经济发展中的政府作为--以青岛市为例

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中国行政管理 2008年第3期 72-75页

作者：王振海青岛行政学院青岛266071

培育品牌企业,增强名牌意识,培植品牌经济,形成品牌优势,提升城市竞争力,是各个地区特别是各个城市关注的焦点问题,也是判断一个城市是否有实力、有活力的重要标志。青岛是全国率先提出"名牌战略"的城市,经过20多年的发展,青岛的名牌战... 详细信息

培育品牌企业,增强名牌意识,培植品牌经济,形成品牌优势,提升城市竞争力,是各个地区特别是各个城市关注的焦点问题,也是判断一个城市是否有实力、有活力的重要标志。青岛是全国率先提出"名牌战略"的城市,经过20多年的发展,青岛的名牌战略获得了巨大成功,培育和成长出了一批享誉国内外的名牌产品和名牌企业。在培育品牌企业中政府应该发挥哪些作用,是人们普遍关心的问题。本文围绕这一问题,介绍了青岛市政府在培育品牌企业中的重要举措,以期促进对该问题的进一步研究。

关键词：品牌品牌经济政府作为

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基于深度学习的波长调制吸收光谱非线性层析重建研究

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燃烧科学与技术 2022年第6期28卷 659-666页

作者：王振海超星清华大学能源与动力工程系燃烧能源中心北京100084

本文基于深度学习算法,开展了免标定波长调制吸收光谱非线性层析重建研究.采用频分复用技术,构建吸收光谱非线性层析重建方案,使用5条吸收谱线、2个投影角度共计20条投影光线.以二维温度场重建为例,在无噪声时温度场平均重建误差为2.85%... 详细信息

本文基于深度学习算法,开展了免标定波长调制吸收光谱非线性层析重建研究.采用频分复用技术,构建吸收光谱非线性层析重建方案,使用5条吸收谱线、2个投影角度共计20条投影光线.以二维温度场重建为例,在无噪声时温度场平均重建误差为2.85%,且在不同噪声水平和训练样本数目条件下,该方案可实现高精度温度和浓度场二维重建.本工作首次从算法理论层面实现了二维温度、浓度分布重建,将为实际燃烧环境中非线性层析重建实验提供指导.

关键词：深度学习方法波长调制光谱非线性层析温度场浓度场

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融合奇异值分解和最大间距准则的人脸识别方法

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计算机工程与应用 2011年第8期47卷 164-166页

作者：王振海临沂大学信息学院山东临沂276005

提出了一种融合奇异值分解(SVD)和最大间距准则鉴别分析(MMC)的人脸识别方法。对人脸图像进行奇异值分解,选取较大的一组奇异值构成特征向量,对所有训练样本按照最大间距准则鉴别分析算法计算投影矩阵,把人脸图像矩阵在投影矩阵上投影... 详细信息

提出了一种融合奇异值分解(SVD)和最大间距准则鉴别分析(MMC)的人脸识别方法。对人脸图像进行奇异值分解,选取较大的一组奇异值构成特征向量,对所有训练样本按照最大间距准则鉴别分析算法计算投影矩阵,把人脸图像矩阵在投影矩阵上投影得到特征矩阵。融合决策阶段,在以上两类特征集中,分别计算待识别样本到所有训练样本的欧氏距离并对得到的两类结果进行加权融合,最后根据最近距离分类器分类。基于ORL人脸数据库上的实验结果表明算法的有效性。

关键词：人脸识别奇异值分解最大间距准则

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