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Design method for an acoustic cloak in flows by topology optimization

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Acta Mechanica Sinica 2019年第5期35卷 964-971页

作者： zhengyu ma Oksana Stalnov Xun Huang State Key Laboratory of Turbulence and Complex Systems Department of Aeronautics and AstronauticsCollege of Engineering Peking UniversityBeijingChina Faculty of Aerospace Engineering Technion-Israel Institute of TechnologyHaifaIsrael

In this paper,a design method for an acoustic cloak in the presence of background mean flows is proposed by using topology optimization,which enables the associated fabrication of the cloaking *** density-based topology optimization method is used to allocate the designated materials,thus providing the structure of the *** optimization problem is efficiently solved with the gradient-based globally convergent method of moving asymptotes,which utilizes the derivative information from the finite element simulation studies of the linearized acoustic potential *** paper introduces the whole design method first then numerically demonstrates the corresponding performance,which shall constitute the main contribution of the present work.

关键词： Aeroacoustics Acoustic cloaking Topology optimization

In vitro and in vivo degradation behavior of poly(trimethylene carbonate-co-D,L-lactic acid)copolymer

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Regenerative Biomaterials 2017年第4期4卷 207-213页

作者： zhengyu ma Yi Wu Jing Wang Changsheng Liu Engineering Research Center for Biomedical materials of Ministry of Education School of Materials Science and EngineeeringEast China University of Science and TechnologyShanghai 200237People’s Republic of China The State Key Laboratory of Bioreactor Engineering School of Materials Science and EngineeringEast China University of Science and TechnologyShanghai 200237People’s Republic of China Key Laboratory for Ultrafine materials of Ministry of Education School of Materials Science and EngineeringEast China University of Science and TechnologyShanghai 200237People’s Republic of China

We present P(TMC-co-DLLA)copolymer with the molar ratio of TMC:DLLA紏15:85 was used to systematic study of in vivo and in vitro degradation *** homogeneous copolymer specimens were prepared by compression molding *** in vitro and in vivo degradation were,respectively,performed at simulative body condition and implanted into rat’s subcutaneous *** were followed via physicochemical and histological analysis such as SEM,GPC,DSC,FTIR and H&E *** results demonstrate that copolymeric material can degrade in phosphate buffer solution(PBS)and in rat’s body,and the in vivo degradation rate is *** decline of molecule weight and mass loss has been observed,which led to the attenuation of mechanical ***,apart from the hydrolysis,macrophagocytes took part in the phagocytosis in vivo,indicating that degradation rate could be regulated by the combinational *** is concluded that P(TMC-co-DLLA)copolymer is a promising candidate for tissue repair.

关键词： P(TMC-co-DLLA) copolymer degradation tissue repair

Modulation of Neuronal Activity and Saccades at Theta Rhythm During Visual Search in Non-human Primates

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Neuroscience Bulletin 2022年第10期38卷 1183-1198页

作者： Jin Xie Ting Yan Jie Zhang zhengyu ma Huihui Zhou The Brain Cognition and Brain Disease Institute Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research InstitutionsShenzhen518055China University of Chinese Academy of Sciences Beijing100049China The Research Center for Artificial Intelligence Peng Cheng LaboratoryShenzhen518000China

Active exploratory behaviors have often been associated with theta oscillations in rodents,while theta oscillations during active exploration in non-human primates are still not well *** recorded neural activities in the frontal eye field(FEF)and V4 simultaneously when monkeys performed a free-gaze visual search *** were strongly phase-locked to theta oscillations of V4 and FEF local field potentials,and the phase-locking was dependent on saccade *** spiking probability of V4 and FEF units was significantly modulated by the theta phase in addition to the time-locked modulation associated with the evoked response.V4 and FEF units showed significantly stronger responses following saccades initiated at their preferred *** causality and ridge regression analysis showed modulatory effects of theta oscillations on saccade ***,our study suggests phase-locking of saccades to the theta modulation of neural activity in visual and oculomotor cortical areas,in addition to the theta phase locking caused by saccade-triggered responses.

关键词： Visual search Saccade Theta rhythm FEF V4 Non-human primate

Recombinant sTRAIL induces cell death of tumor cell lines as well as primary cancer cells

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Chinese Science Bulletin 1999年第14期44卷 1306-1309页

作者： Yanxin Liu Xun Zhu zhengyu ma Dexian Zheng Peking Union Med Coll Chinese Acad Med Sci Inst Basic Med Sci Natl Lab Med Mol Biol Beijing 100005 Peoples R China Peking Union Med Coll Chinese Acad Med Sci Inst Hematol Natl Lab Expt Hematol Tianjin 300020 Peoples R China

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a new member of TNF family. It was reported that TRAIL could induce apoptosis of tumor cells but not normal cells in tissue culture system. To further study the biological activity and potential clinical significance, a recombinant soluble TRAIL (rsTRAIL) has been expressed stably in E. coli after transformation of pET28b vector containing the extracellular domain of TRAIL. The yield of rsTRAIL is approximately as high as 60% of whole bacterial proteins. The rsTRAIL, purified by Ni^+ -agarose affinity chromatography, could remarkably trigger apoptosis at the concentrations of 0.1—1 μg/mL in all 7 tumor cell lines tested in vitro. However, this killing activity has not been observed in mouse fibroblast cell line (NIH3T3) as normal control. Further investigation shows that the rsTRAIL could also kill primary tumor cells isolated freshly from patients with cardiac cancer, breast cancer and malignant thymoma, while the normal human

关键词： rsTRAIL apoptosis primary cancer cells.

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小学语文教师教育哲学取向的特点与启示

课程．教材．教法 2017年第5期37卷 100-106页

作者：马郑豫西南大学教育学部重庆400715

小学语文教师的教育哲学取向呈现出以现实主义和经验主义为主导,永恒主义、理想主义和存在主义并存的模式,且小学语文教师的不同教育哲学取向在年龄、教龄、受教育程度和是否担任职务上存在显著差异。基础教育和新课程改革的现实需求,... 详细信息

小学语文教师的教育哲学取向呈现出以现实主义和经验主义为主导,永恒主义、理想主义和存在主义并存的模式,且小学语文教师的不同教育哲学取向在年龄、教龄、受教育程度和是否担任职务上存在显著差异。基础教育和新课程改革的现实需求,迫切需要我们提升小学语文教师的教育哲学意识。通过探索教师学习教育哲学的可行路径,丰富语文教师的教育哲学理论来推动语文教育的发展。

关键词：教育哲学取向小学语文教师

童年期友谊质量与孤独感的纵向发展关系:应对方式的共变作用分析

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心理发展与教育 2023年第1期39卷 31-39页

作者：苏志强马郑豫长江师范学院教师教育学院重庆408100

为了揭示童年期友谊质量与孤独感的纵向发展关系,以771名小学3、4年级学生为对象,采用友谊质量问卷、孤独感问卷和应对方式问卷进行了为期2年的纵向追踪。结果表明:(1)在纵向发展上,童年期儿童的友谊质量无法持续稳定地预测孤独感的纵... 详细信息

为了揭示童年期友谊质量与孤独感的纵向发展关系,以771名小学3、4年级学生为对象,采用友谊质量问卷、孤独感问卷和应对方式问卷进行了为期2年的纵向追踪。结果表明:(1)在纵向发展上,童年期儿童的友谊质量无法持续稳定地预测孤独感的纵向发展,但孤独感可以持续显著预测友谊质量的发展;(2)童年期儿童的应对方式既可以显著预测友谊质量的纵向发展,也可以显著预测孤独感的纵向发展。结论:在纵向发展上,童年期儿童的友谊质量与孤独感呈共同变化关系,两者的发展轨迹均受第三因素——应对方式发展的影响。

关键词：友谊质量孤独感应对方式共同变化儿童

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小学生孤独感纵向发展特征的追踪研究

中国学校卫生 2020年第10期41卷 1533-1535页

作者：马郑豫苏志强长江师范学院教师教育学院重庆408100

目的探讨小学生孤独感的纵向发展特征及其性别差异,为学校心理健康教育工作的高效开展提供实证参考。方法采用儿童孤独感量表,对广州中山和四川达州的771名小学三四年级学生进行为期2年的纵向追踪(2014年6月—2016年6月),每半年施测一次... 详细信息

目的探讨小学生孤独感的纵向发展特征及其性别差异,为学校心理健康教育工作的高效开展提供实证参考。方法采用儿童孤独感量表,对广州中山和四川达州的771名小学三四年级学生进行为期2年的纵向追踪(2014年6月—2016年6月),每半年施测一次,共收集到5组调查数据。结果小学生5次追踪孤独感得分分别为(33.96±12.77)(31.13±12.82)(29.66±12.65)(28.67±11.97)(27.60±11.63)分。孤独感在童年中期有着较快的下降速度(eta1=-2.61,P0.05)。结论小学生孤独感的发展为非线性的曲线发展,整体呈现出先长时程下降后缓慢上升的发展趋势。

关键词：孤独精神卫生纵向研究学生

童年期抑郁情绪发展的异质性与可预测性:2年追踪研究

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心理发展与教育 2021年第1期37卷 84-91页

作者：苏志强马郑豫长江师范学院教师教育学院重庆408100

以儿童抑郁量表为研究工具,对小学3到4年级771名儿童进行了2年的追踪研究。采用潜类别增长模型和终端结局潜发展模型,分别考察了童年期儿童抑郁情绪发展的亚群组类型,以及儿童抑郁情绪的发展特征对观察期结束时抑郁情绪的预测作用。结... 详细信息

以儿童抑郁量表为研究工具,对小学3到4年级771名儿童进行了2年的追踪研究。采用潜类别增长模型和终端结局潜发展模型,分别考察了童年期儿童抑郁情绪发展的亚群组类型,以及儿童抑郁情绪的发展特征对观察期结束时抑郁情绪的预测作用。结果表明:(1)童年期儿童的抑郁情绪发展呈现出三种不同的亚类型,即抑郁高风险组、抑郁低风险组和抑郁自愈组,各类型组人数比例分别为9.6%、53.4%和36.8%;(2)童年期儿童抑郁情绪的初始水平及其发展变化率均可以显著预测观察期结束时的抑郁情绪状况。童年期儿童抑郁情绪的早期监测工作有着重要的实践意义。

关键词：抑郁亚群组终端结局预测儿童

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中小学学生学习策略的调查研究

教育研究 2015年第6期36卷 85-95页

作者：马郑豫张家军西南大学教育学部

通过《中小学学生学习策略问卷》对全国11个省市13 477名的小学、初中、高中学生的调查,发现中小学学生呈现出以"复述策略"、"时间管理策略"和"物力资源利用策略"为主导,其他学习策略兼顾应用的现状;中小学学生学习策略的应用在年龄方... 详细信息

通过《中小学学生学习策略问卷》对全国11个省市13 477名的小学、初中、高中学生的调查,发现中小学学生呈现出以"复述策略"、"时间管理策略"和"物力资源利用策略"为主导,其他学习策略兼顾应用的现状;中小学学生学习策略的应用在年龄方面呈现"U"型发展,性别差异和城乡差异都表现出相同特点:小学和初中阶段,女生和城镇学校学生对各种学习策略的运用要好于男生和农村学校学生;东部地区学生的学习策略运用显著好于中西部地区学生;不同学业水平的学生,在七种学习策略上的得分存在显著差异。应高度重视中小学学生学习策略的重要意义,多种方式加强学习策略的指导与建构,加强初中学生学习策略的指导与应用,重视对中西部地区的学生、农村学校的学生以及男生群体学习策略的运用,结合教学展开学习策略训练,提升学习效率。

关键词：中小学学生学习策略横断分析