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Chinese Journal of Chemistry 2024年第19期42卷 2357-2362页

作者： zhengnan zhou Can Li Shengming Ma State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic ChemistryChinese Academy of Sciences345 Lingling LuShanghai 200032China University of Chinese Academy of Sciences Bejjing 100049China Research Center for Molecular Recognition and Synthesis Department of ChemistryFudan University220 Handan LuShanghai 200433China

Comprehensive Summary 2,3-Allenyl amines have shown wide applicability in biomedical and synthetic *** to their enormous potential for applications,researchers have been dedicated to the development of methods for synthesizing 2,3-allenyl ***,a palladium-catalyzed three-component reaction of 2-alkynyl-1,4-diol dicarbonates,organoboronic acids,and nitrogen nucleophiles forming 2,3-allenyl amines with excellent regio-and chemo-selectivity has been *** compatibility and synthetic applications have been *** experiments supported a mechanism involving 1,2,3-triene-Pd species and methylene-π-allyl palladium species.

关键词： Pd catalysis 2,3-Allenyl amine Alk-2-yn-1,4-diol dicarbonate Organoboronic acid 1,2,3-Triene Methylene-π-allyl palladium species Regioselectivity Chemoselectivity

Controllable Protein Adsorption and Bacterial Adhesion on Polypyrrole Nanocone Arrays

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Journal of Materials Science & Technology 2016年第9期32卷 950-955页

作者： zhengnan zhou Weiping Li Tianrui He Peng Yu Guoxin Tan Chengyun Ning School of Materials Science and Engineering South China University of Technology Guangdong Key Laboratory of Biomedical Sciences and Engineering South China University of Technology School of Chemical Engineering and Light Industry Guangdong University of Technology

In this research, polypyrrole nanocone arrays doped with β-Naphthalene sulphonic acid （PPy-NSA） were built. This film was expected to control protein adsorption and bacterial adhesion by potential-induced reversibly redox. The scanning Kelvin probe microscopy （SKPM） and surface contact angles （SCA） tests suggested that the surface potential and wettability of PPy-NSA nanocone arrays could be controlled by simply controlling its redox property via applying potential. The controllable surface potential and wettability in return controlled the adsorption of protein and adhesion of bacteria. The proposed material might find application in the preparation of smart biomaterial surfaces that can regulate proteins and bacterial adhesion by a simple potential switching.

关键词： Polypyrrole Protein adsorption Bacterial adhesion Nanocone arrays Control

Urban surface water system in coastal areas: A comparative study between Almere and Tianjin Eco-city

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Open Journal of Ecology 2013年第6期3卷 407-416页

作者： Tao Zou zhengnan zhou Beijing Tsinghua Tongheng Urban Planning and Design Institute Beijing China School of Architecture Tsinghua University Beijing China

In the purpose of defining typical urban water management challenges in coastal lowlands in the context of global climate change, a comparative study was conducted between two coastal new towns respectively located in the Netherlands and Northern China. Comparative method is applied to define main functioning patterns of urban water systems in the two cases, then computer simulations were used to furthercompare drainage capacity in order to reveal the trends of urban water management. Major resulthas shown that Almere in the Netherlands generally more advanced in urban water management asmultiple functioning patterns are *** dykes maintain competence for land subsidence and sea level rise. Open water system decreases local runoff and increaseswater retention level. Systematic control ofsluicesand locks which serve for shipping and waterfront landscaping are simultaneously isolating contaminants from outer water body. Tianjin Eco-city in China has shown both strengths and weaknesses. It takes large amount of reclaimed water as main landscaping water source, which adapts to local water pollution and shortage while requires highly centralized facilities. Large water body is reserved and huge scale underground drainage system built, but it is still vulnerable to heavy storms due to the lack of efficient surface water drainage system. Coastal line control does not adequately prevent from increasing storm surge risks in the future. SWMMsimulations have supported the viewpoint ofdistributed surface water with a higher efficiency for storm drainage. Meanwhile, surface water system returns more added values to urban development. The study is corresponding well with the theory of water sensitive city. As a conclusion, urban water system should always incorporate methods to achieve higher system resilience based on multiple functioning patterns.

关键词： Urban Surface Water System Urban Water Management Coastal Areas SWMM

Wireless electrical stimulation at the nanoscale interface induces tumor vascular normalization

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Bioactive Materials 2022年第12期7卷 399-408页

作者： Changhao Li Cairong Xiao Lizhen Zhan Zhekun Zhang Jun Xing Jinxia Zhai zhengnan zhou Guoxin Tan Jinhua Piao Yahong zhou Suijian Qi Zhengao Wang Peng Yu Chengyun Ning School of Material Science and Engineering National Engineering Research Center for Tissue Restoration and ReconstructionMetallic Materials Surface Functionalization Engineering Research Center of Guangdong ProvinceSouth China University of TechnologyGuangzhou510641China School of Food Science and Engineering South China University of TechnologyGuangzhou510641China CAS Key Laboratory of Bio-inspired Materials and Interfacial Science Technical Institute of Physics and ChemistryChinese Academy of ScienceBeijing100190China School of Chemical Engineering and Light Industry Guangdong University of TechnologyGuangzhou510006China China-Singapore International Joint Research Institute Guangzhou511365China

Pathological angiogenesis frequently occurs in tumor tissue, limiting the efficiency of chemotherapeutic drug delivery and accelerating tumor progression. However, traditional vascular normalization strategies are not fully effective and limited by the development of resistance. Herein, inspired by the intervention of endogenous bioelectricity in vessel formation, we propose a wireless electrical stimulation therapeutic strategy, capable of breaking bioelectric homeostasis within cells, to achieve tumor vascular normalization. Polarized barium titanate nanoparticles with high mechano-electrical conversion performance were developed, which could generate pulsed open-circuit voltage under low-intensity pulsed ultrasound. We demonstrated that wireless electrical stimulation significantly inhibited endothelial cell migration and differentiation in vitro. Interestingly, we found that the angiogenesis-related eNOS/NO pathway was inhibited, which could be attributed to the destruction of the intracellular calcium ion gradient by wireless electrical stimulation. In vivo tumor-bearing mouse model indicated that wireless electrical stimulation normalized tumor vasculature by optimizing vascular structure, enhancing blood perfusion, reducing vascular leakage, and restoring local oxygenation. Ultimately, the anti-tumor efficacy of combination treatment was 1.8 times that of the single chemotherapeutic drug doxorubicin group. This work provides a wireless electrical stimulation strategy based on the mechano-electrical conversion performance of piezoelectric nanoparticles, which is expected to achieve safe and effective clinical adjuvant treatment of malignant tumors.

关键词： Calcium distribution Mechano-electrical conversion Piezoelectric barium titanate Tumor vascular normalization Wireless electrical stimulation

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关于建筑传媒手段的思考

建筑学报 2000年第9期 41-43页

作者：周正楠清华大学建筑学院

本文力图说明城市建筑具有社会信息媒介的功能 ,并寻求如何使城市建筑更好地传播社会信息 ,如何使传播信息的方式与城市建筑的形式更好地结合 ,形成更好的城市建筑景观的方法。

关键词：建筑传媒手段传媒要素城市建筑

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对欧洲“被动房”建筑的介绍与思考

建筑学报 2009年第5期 10-13页

作者：周正楠清华大学建筑学院北京100084 荷兰代尔夫特理工大学建筑学院

介绍"被动房"建筑的定义、创建历史、标准等基本情况,归纳其设计和建造中加强建筑围护体系的保温性能、提高建筑的气密性、机械送新风并进行热回收、低热负荷的采暖方式等4个方面的主要技术措施,提出建造多样化"被动房"建筑、提高性价... 详细信息

介绍"被动房"建筑的定义、创建历史、标准等基本情况,归纳其设计和建造中加强建筑围护体系的保温性能、提高建筑的气密性、机械送新风并进行热回收、低热负荷的采暖方式等4个方面的主要技术措施,提出建造多样化"被动房"建筑、提高性价比、建立基于"被动房"理念的设计方法等发展方向,并分析"被动房"建筑在中国的应用前景。

关键词： “被动房”建筑节能建筑采暖

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北京大兴被动式实验农宅设计与实测分析

建筑学报 2015年第3期 93-97页

作者：周正楠清华大学建筑学院北京100084

阐述北京大兴被动式实验农宅项目的设计策略,并对其实际使用状况进行实测分析,探讨了通过被动式技术实现北方地区农宅建筑冬季不采暖的途径及其实际效果。

关键词：被动式技术北京大兴实验农宅实测分析

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太阳能技术在德国建筑中的应用

世界建筑 2002年第12期 54-55页

作者：周正楠清华大学建筑学院

本文通过具体介绍德国3个建筑实例中的相关内容,对太阳能技术在建筑中的运用作了较为深入的分析。

关键词：太阳能建筑建筑设计居住区德国

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解读清华大学超低能耗示范楼

建筑学报 2005年第9期 16-17页

作者：栗德祥周正楠清华大学建筑学院北京100084

本文以建筑设计者的角度,从五个方面对清华大学超低能耗示范楼在生态设计上所采用的策略和各种生态技术做了概括和总结。

关键词：超低能耗示范楼生态策略清华大学低能耗示范解读生态技术生态设计设计者建筑

基于RSA加密技术的数字化电能表计量数据安全采集方法

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通信电源技术 2024年第23期41卷 25-27页

作者：周政男国网湖北省电力有限公司利川市供电公司湖北利川445400

针对现有采集方法存在的采集数据准确性较差、数据丢失和损坏的问题,引入RSA加密技术,设计了一种数字化电能表计量数据安全采集方法。该方法利用远程无线通信技术传输数据,并通过RSA算法生成加密与解密的密钥,从而确保数字化电能表计量... 详细信息

针对现有采集方法存在的采集数据准确性较差、数据丢失和损坏的问题,引入RSA加密技术,设计了一种数字化电能表计量数据安全采集方法。该方法利用远程无线通信技术传输数据,并通过RSA算法生成加密与解密的密钥,从而确保数字化电能表计量数据的安全采集。通过对比实验证明,文章提出的采集方法能够实现对电能表计量数据的准确采集,并且在数据传输过程中能够及时修复丢失和损坏的数据,具有极高的应用价值。

关键词：远程无线通信电能表安全采集计量数据数字化