检索结果-南通市图书馆

Fiber-Reinforced Silk Microneedle Patches for Improved Tissue Adhesion in Treating Diabetic Wound Infections

Advanced Fiber Materials 2024年第5期6卷 1596-1615页

作者： Yixin Wang Pengpeng Guan Ruiyi Tan zhenghui shi Qing Li Bitao Lu Enling Hu Weiwei Ding Wenyi Wang Bowen Cheng Guangqian Lan Fei Lu State Key Laboratory of Resource Insects College of SericultureTextile and Biomass SciencesSouthwest UniversityChongqing 400715China Chongqing Engineering Research Center of Biomaterial Fiber and Modern Textile Chongqing 400715China Division of Trauma and Surgical Intensive Care Unit Research Institute of General SurgeryJinling HospitalMedical School of Nanjing UniversityNanjing 210002Jiangsu ProvinceChina Department of Applied Biology and Chemical Technology The Hong Kong Polytechnic UniversityHung HomHong KongChina School of Textile Science and Engineering Tianjin Polytechnic UniversityTianjin 300387China

Microneedles(MNs)with unique three-dimensional stereochemical structures are suitable candidates for tissue fixation and drug ***,existing hydrogel MNs exhibit poor mechanical properties after swelling and require complex preparation procedures,impeding their practical ***,we engineered chitosan fiber-reinforced silk fibroin MN patches containing epigallocatechin gallate(SCEMN).A formic acid-calcium chloride system was introduced to fabricate hydrogel MNs with excellent inherent adhesion,and the incorporation of chitosan fiber as a reinforcing material enhanced mechanical strength and viscosity,thereby increasing the physical interlocking with tissue and the ability to maintain *** SCEMN with a lower insertion force firmly adhered to porcine skin,with a maximum detachment force of 11.98 N/***,SCEMN has excellent antioxidant and antibacterial properties,facilitates macrophage polarization from M1 to M2,and demonstrates superior performance in vivo for diabetic wound repair compared with the commercial product Tegaderm^(TM).This study represents the first trial of fiber-reinforced hydrogel MNs for robust tissue *** findings underscore the significance of this innovative approach for advancing MN technology to enhance tissue adhesion and accel-erate wound healing.

关键词： Fibrous reinforcement Double-sided microneedle patch Swellable hydrogel Tissue adhesion

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

东海西湖凹陷构造演化及控煤作用

引用

煤田地质与勘探 2016年第5期44卷 22-27页

作者：李居云姜波屈争辉尹诗许将李佩中国煤炭地质总局航测遥感局陕西西安710199 中国矿业大学资源与地球科学学院江苏徐州221116 河南省地质矿产勘查开发局第四地质勘察院河南郑州450001

西湖凹陷是经历了多期构造作用的新生代弧后盆地。在对其区域构造和其内部构造特征分析的基础上,利用平衡剖面技术,探讨西湖凹陷构造演化特征及控煤作用。研究结果表明:西湖凹陷具有"东西分带、南北分块"的构造格局;受区域演化的影响,... 详细信息

西湖凹陷是经历了多期构造作用的新生代弧后盆地。在对其区域构造和其内部构造特征分析的基础上,利用平衡剖面技术,探讨西湖凹陷构造演化特征及控煤作用。研究结果表明:西湖凹陷具有"东西分带、南北分块"的构造格局;受区域演化的影响,西湖凹陷构造演化可分为断陷期、坳陷期和区域沉降期;聚煤前的平坦地形、聚煤期的同沉积构造坡折带的发育及聚煤期后一系列反转构造,造就了西湖凹陷现今煤层气赋存特征。

关键词：西湖凹陷平衡剖面构造演化构造控煤

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Novel loci and potential mechanisms of major depressive disorder,bipolar disorder,and schizophrenia

引用

Science China(Life Sciences) 2022年第1期65卷 167-183页

作者： He Wang zhenghui Yi Tieliu shi Center for Bioinformatics and Computational Biology Institute of Biomedical Sciences and School of Life SciencesEast China Normal UniversityShanghai 200241China Shanghai Mental Health Center Shanghai Jiao Tong University School of MedicineShanghai 200030China Key Laboratory of Advanced Theory and Application in Statistics and Data Science-MOE School of StatisticsEast China Normal UniversityShanghai 200062China Beijing Advanced Innovation Center for Big Data-Based Precision Medicine Beihang University&Capital Medical UniversityBeijing 100083China

Different psychiatric disorders share genetic relationships and pleiotropic loci to certain *** integrated and analyzed datasets related to major depressive disorder(MDD),bipolar disorder(BIP),and schizophrenia(SCZ)from the Psychiatric Genomics Consortium using multitrait analysis of genome-wide association analysis(MTAG).MTAG significantly increased the effective sample size from 99,773 to 119,754 for MDD,from 909,061 to 1,450,972 for BIP,and from 856,677 to 940,613 for *** discovered 7,32,and 43 novel lead single nucleotide polymorphisms(SNPs)and 1,6,and 3 novel causal SNPs for MDD,BIP,and SCZ,respectively,after *** identified rs8039305 in the FURIN gene as a novel pleiotropic locus across the three *** performed marker analysis of genomic annotation(MAGMA)and Hi-C-coupled MAGMA(H-MAGMA)based gene-set analysis and identified 101 genes associated with the three disorders,which were enriched in the regulation of postsynaptic membranes,postsynaptic membrane dopaminergic synapses,and Notch signaling ***,we performed Mendelian randomization analysis using different tools and detected a causal effect of BIP on ***,we demonstrated the usage of combined genome-wide association studies summary statistics for exploring potential novel mechanisms of the three psychiatric disorders,providing an alternative approach to integrate publicly available summary data.

关键词： psychiatric disorders multitrait analysis of genome-wide association analysis novel loci Mendelian randomization causal effects

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A soil moisture assimilation scheme based on the ensemble Kalman filter using microwave brightness temperature

引用

Science China Earth Sciences 2009年第11期52卷 1835-1848页

作者： BingHao Jia zhenghui Xie XiangJun Tian ChunXiang shi ICCES/LASG Institute of Atmospheric Physics Chinese Academy of Sciences Beijing 100029 China Graduate University of Chinese Academy of Sciences Beijing 100049 China National Satellite Meteorological Center China Meteorological Administration Beijing 100081 China

This study presents a soil moisture assimilation scheme, which could assimilate microwave brightness temperature directly, based on the ensemble Kalman filter and the shuffled complex evolution method (SCE-UA). It uses the soil water model of the land surface model CLM3.0 as the forecast operator, and a radiative transfer model (RTM) as the observation operator in the assimilation system. The assimilation scheme is implemented in two phases: the parameter calibration phase and the pure soil moisture assimilation phase. The vegetation optical thickness and surface roughness parameters in the RTM are calibrated by SCE-UA method and the optimal parameters are used as the final model parameters of the observation operator in the assimilation phase. The ideal experiments with synthetic data indicate that this scheme could significantly improve the simulation of soil moisture at the surface layer. Further- more, the estimation of soil moisture in the deeper layers could also be improved to a certain extent. The real assimilation experiments with AMSR-E brightness temperature at 10.65 GHz (vertical polariza- tion) show that the root mean square error (RMSE) of soil moisture in the top layer (0―10 cm) by as- similation is 0.03355 m3·m-3, which is reduced by 33.6% compared with that by simulation (0.05052 m3·m-3). The mean RMSE by assimilation for the deeper layers (10―50 cm) is also reduced by 20.9%. All these experiments demonstrate the reasonability of the assimilation scheme developed in this study.

关键词： land data assimilation soil moisture ensemble Kalman filter SCE-UA method radiative transfer model AMSR-E

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Ensemble Simulation of Land Evapotranspiration in China Based on a Multi-Forcing and Multi-Model Approach

引用

Advances in Atmospheric Sciences 2016年第6期33卷 673-684页

作者： Jianguo LIU Binghao JIA zhenghui XIE Chunxiang shi High Performance Computing Center School of Mathematics and Computational ScienceHuaihua University State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute of Atmospheric PhysicsChinese Academy of Sciences National Meteorological Information Center China Meteorological Administration

In order to reduce the uncertainty of offline land surface model （LSM） simulations of land evapotranspiration （ET）, we used ensemble simulations based on three meteorological forcing datasets [Princeton, ITPCAS （Institute of Tibetan Plateau Research, Chinese Academy of Sciences）, Qian] and four LSMs （BATS, VIC, CLM3.0 and CLM3.5）, to explore the trends and spatiotemporal characteristics of ET, as well as the spatiotemporal pattern of ET in response to climate factors over China's Mainland during 1982-2007. The results showed that various simulations of each member and their arithmetic mean （EnsAVlean） could capture the spatial distribution and seasonal pattern of ET sufficiently well, where they exhibited more significant spatial and seasonal variation in the ET compared with observation-based ET estimates （Obs_MTE）. For the mean annual ET, we found that the BATS forced by Princeton forcing overestimated the annual mean ET compared with Obs_MTE for most of the basins in China, whereas the VIC forced by Princeton forcing showed underestimations. By contrast, the Ens_Mean was closer to Obs_MTE, although the results were underestimated over Southeast China. Furthermore, both the Obs_MTE and Ens_Mean exhibited a significant increasing trend during 1982-98; whereas after 1998, when the last big EI Nifio event occurred, the Ens_Mean tended to decrease significantly between 1999 and 2007, although the change was not significant for Obs_MTE. Changes in air temperature and shortwave radiation played key roles in the long-term variation in ET over the humid area of China, but precipitation mainly controlled the long-term variation in ET in arid and semi-arid areas of China.

关键词： land evapotranspiration ensemble simulations multi-forcing and multi-model approach spatiotemporal varia-tion uncertainty

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

PCB钻铣床系统智能化问题研究

引用

深圳信息职业技术学院学报 2010年第2期8卷 44-49页

作者：刘广超周学才马海阳施政辉深圳信息职业技术学院深圳518029 深圳市冰海科技有限公司深圳518059

在数控机床满足了速度、精度以及稳定性的需求后,其控制系统智能化程度的重要性就凸现出来。控制系统智能化直接关系到机床加工效率的高低以及操控便捷与否。本文就PCB机械加工制程中一些重要环节如何实现智能化操控进行深入探讨。

关键词：断刀检测刀径检测象限转换自动换刀运动控制

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

China land soil moisture EnKF data assimilation based on satellite remote sensing data

引用

Science China Earth Sciences 2011年第9期54卷 1430-1440页

作者： shi ChunXiang XIE zhenghui QIAN Hui LIANG MiaoLing YANG XiaoChun National Satellite Meteorological Center China Meteorological Administration Beijing 100081 China Institute of Atmospheric Physics Chinese Academy of Sciences Beijing 100029 China Institute of Geology Chinese Academy of Geological Sciences Key Geodynamics Laboratory the Ministry of Land and Resources Beijing 100037 China National Meteorological Center China Meteorological Administration Beijing 100081 China

Soil moisture plays an important role in land-atmosphere interactions. It is an important geophysical parameter in research on climate, hydrology, agriculture, and forestry. Soil moisture has important climatic effects by influencing ground evapotranspi ration, runoff, surface reflectivity, surface emissivity, surface sensible heat and latent heat flux. At the global scale, the extent of its influence on the atmosphere is second only to that of sea surface temperature. At the terrestrial scale, its influence is even greater than that of sea surface temperatures. This paper presents a China Land Soil Moisture Data Assimilation System (CLSMDAS) based on EnKF and land process models, and results of the application of this system in the China Land Soil Moisture Data Assimilation tests. CLSMDAS is comprised of the following components: 1) A land process mo del—Community Land Model Version 3.0 (CLM3.0)—developed by the US National Center for Atmospheric Research (NCAR); 2) Precipitation of atmospheric forcing data and surface-incident solar radiation data come from hourly outputs of the FY2 geostationary meteorological satellite; 3) EnKF (Ensemble Kalman Filter) land data assimilation method; and 4) Observa tion data including satellite-inverted soil moisture outputs of the AMSR-E satellite and soil moisture observation data. Results of soil moisture assimilation tests from June to September 2006 were analyzed with CLSMDAS. Both simulation and assimila tion results of the land model reflected reasonably the temporal-spatial distribution of soil moisture. The assimilated soil mois ture distribution matches very well with severe summer droughts in Chongqing and Sichuan Province in August 2006, the worst since the foundation of the People’s Republic of China in 1949. It also matches drought regions that occurred in eastern Hubei and southern Guangxi in September.

关键词： EnKF land data assimilation AMSR-E soil moisture FY2C geostationary satellite high-resolution precipitation surface incident solar radiation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Wetting sub-nanochannels via ionic hydration effect for improving charging dynamics

引用

Green Energy & Environment 2024年第3期9卷 473-480页

作者： Yayun shi Xiaoli Zhao Qihang Liu zhenghui Pan Congcong Liu Shanyi Zhu Zhijun Zuo Xiaowei Yang State Key Laboratory of Clean and Efficient Coal Utilization Taiyuan University of TechnologyTaiyuan030024China School of Materials Science and Engineering Tongji UniversityShanghai201804China School of Chemistry and Chemical Engineering Shanghai Jiao Tong UniversityShanghai200240China

The ionic transport in sub-nanochannels plays a key role in energy storage,yet suffers from a high energy *** sub-nanochannels is crucial to accelerate ionic transport,but the introduction of water is challenging because of the hydrophobic extreme *** propose wetting the channels by the exothermic hydration process of pre-intercalated ions,the effect of which varies distinctly with different ionic hydration structures and *** to the failed pre-intercalation of SO_(4)^(2-),HSO_(4)^(-) with weak hydration energy results in a marginal effect on the HOMO(Highest Occupied Molecular Orbital)level of water to avoid water splitting during the electrochemical ***,the ability of water introduction is reserved by the initial incomplete dissociation state of HSO_(4)^(-),so the consequent exothermic reionization and hydration processes of the intercalated HSO_(4)^(-) promote the water introduction into sub-nanochannels,finally forming the stable confined water through hydrogen bonding with functional *** wetted channels exhibit a significantly enhanced ionic diffusion coef-ficient by~9.4 times.

关键词： Sub-nanochannels Ionic hydration Ionic transport Supercapacitors Confined water

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Elucidating Dominant Factors Affecting Land Surface Hydrological Simulations of the Community Land Model over China

引用

Advances in Atmospheric Sciences 2023年第2期40卷 235-250页

作者： Jianguo LIU Zong-Liang YANG Binghao JIA Longhuan WANG Ping WANG zhenghui XIE Chunxiang shi School of Mathematics and Computational Science and Key Laboratory of Intelligent Control Technology for Wuling-Mountain Ecological Agriculture in Hunan ProvinceHuaihua UniversityHuaihuaHunan 418008China Department of Geological Sciences The John A.and Katherine G.Jackson School of GeosciencesUniversity of Texas at AustinAustinTexas 78712-1722USA State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics(LASG) Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China National Meteorological Information Center China Meteorological AdministrationBeijing 100081China

In order to compare the impacts of the choice of land surface model(LSM)parameterization schemes,meteorological forcing,and land surface parameters on land surface hydrological simulations,and explore to what extent the quality can be improved,a series of experiments with different LSMs,forcing datasets,and parameter datasets concerning soil texture and land cover were *** simulations are run for the Chinese mainland on 0.1°×0.1°grids from 1979 to 2008,and the simulated monthly soil moisture(SM),evapotranspiration(ET),and snow depth(SD)are then compared and assessed against *** results show that the meteorological forcing is the most important factor governing *** that,SM seems to be also very sensitive to soil texture information;SD is also very sensitive to snow parameterization scheme in the *** Community Land Model version 4.5(CLM4.5),driven by newly developed observation-based regional meteorological forcing and land surface parameters(referred to as CMFD_CLM4.5_NEW),significantly improved the simulations in most cases over the Chinese mainland and its eight *** increased the correlation coefficient values from 0.46 to 0.54 for the SM modeling and from 0.54 to 0.67 for the SD simulations,and it decreased the root-mean-square error(RMSE)from 0.093 to 0.085 for the SM simulation and reduced the normalized RMSE from 1.277 to 0.201 for the SD *** study indicates that the offline LSM simulation using a refined LSM driven by newly developed observation-based regional meteorological forcing and land surface parameters can better model reginal land surface hydrological processes.

关键词： hydrological simulations land surface model meteorological forcing land surface parameters uncertainty

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

表面肌电监测在引体向上教学训练中的应用研究

引用

空军军医大学学报 2024年第11期45卷 1257-1261页

作者：翟明明师正辉李远辙张晨旭罗二平汤池空军军医大学军事生物医学工程学系陕西西安710032 空军军医大学陕西省生物电磁检测与智能感知重点实验室陕西西安710032

目的针对军队男性文职人员体能考核引体向上科目及格率较低、训练效果不理想的问题,基于人因工程学表面肌电监测方法对受试者引体向上运动进行分析,探究表面肌电信号辅助引体向上教学训练是否可行。方法随机选取5名男性社会招聘文职人员... 详细信息

目的针对军队男性文职人员体能考核引体向上科目及格率较低、训练效果不理想的问题,基于人因工程学表面肌电监测方法对受试者引体向上运动进行分析,探究表面肌电信号辅助引体向上教学训练是否可行。方法随机选取5名男性社会招聘文职人员,通过监测其引体向上运动过程中肱桡肌、肱二头肌、三角肌后束、斜方肌和背阔肌电信号,选用肌肉激活强度、贡献率和激活时序3个参数分析受试者技术动作特性。结果肌电监测数据显示,受试者肌肉激活强度、贡献率和肌肉激活时序等与标准引体向上存在差异。受试者主发力肌群为肱桡肌和肱二头肌,斜方肌与背阔肌激活不足,导致三角肌后束与肱二头肌代偿发力,作为辅助肌群的三角肌后束贡献率高于背阔肌。结论表面肌电监测可将视觉无法观察到的内在肌肉动作以肌电信号形式呈现,辅助教员及时分析受试者的技术动作特性,为后续进行针对性训练指导提供参考。

关键词：表面肌电引体向上体能训练体育教学

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：