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工具技术 2001年第5期35卷 22-25页

作者：戚正风 Qi zhengfeng 大连铁道学院 (116028)

介绍了作者新开发的M2Si系列高速钢 (包括M2Si 1低碳高速钢、M2Si 2通用高速钢、M2Si 3高碳高速钢和M2Si 4超硬高速钢 )的成分特点、组织形态和机械性能。

关键词：高速钢成分组织机械性能

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合成双吲哚甲烷类衍生物的研究进展

有机化学 2012年第7期32卷 1195-1207页

作者：宫海伟解正峰新疆大学化学化工学院石油天然气精细化工教育部重点实验室 830046

双吲哚甲烷类衍生物具有丰富的生物活性和药理活性,在医药领域得到了广泛的应用.近年来,对双吲哚甲烷类衍生物的合成研究引起了人们的热点关注.对双吲哚甲烷类衍生物的合成方法进行了综述,并将催化剂按照不同的类型分为:(1)路易斯酸催化... 详细信息

双吲哚甲烷类衍生物具有丰富的生物活性和药理活性,在医药领域得到了广泛的应用.近年来,对双吲哚甲烷类衍生物的合成研究引起了人们的热点关注.对双吲哚甲烷类衍生物的合成方法进行了综述,并将催化剂按照不同的类型分为:(1)路易斯酸催化剂,(2)分子碘催化剂,(3)质子酸催化剂,(4)固载催化剂,(5)杂多酸催化剂,(6)有机小分子催化剂,(7)配合物催化剂,(8)离子液体催化剂,(9)其它类型的催化剂.

关键词：双吲哚甲烷衍生物合成催化剂研究进展

Stable cycling of practical high-voltage LiCoO_(2)pouch cell via electrolyte modification

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Nano Research 2023年第3期16卷 3864-3871页

作者： Chao Tang Yawei Chen zhengfeng Zhang Wenqiang Li Junhua Jian Yulin Jie Fanyang Huang Yehu Han Wanxia Li Fuping Ai Ruiguo Cao Pengfei Yan Yuhao Lu Shuhong Jiao Hefei National Laboratory for Physical Science at Microscale CAS Key Laboratory of Materials for Energy ConversionDepartment of Materials Science and EngineeringUniversity of Science and Technology of ChinaHefei 230026China Ningde Amperex Technology limited(ATL) Ningde 352100China Beijing Key Laboratory of Microstructure and Properties of Solids Faculty of Materials and ManufacturingBeijing University of TechnologyBeijing 100124China

Nitriles as efficient electrolyte additives are widely used in high-voltage lithium-ion ***,their working mechanisms are still mysterious,especially in practical high-voltage LiCoO_(2)pouch lithium-ion ***,we adopt a tridentate ligandcontaining 1,3,6-hexanetricarbonitrile(HTCN)as an effective electrolyte additive to shed light on the mechanism of stabilizing high-voltage LiCoO_(2)cathode(4.5 V)through *** LiCoO_(2)/graphite pouch cells with the HTCN additive electrolyte possess superior cycling performance,90%retention of the initial capacity after 800 cycles at 25℃,and 72%retention after 500 cycles at 45℃,which is feasible for practical *** an excellent cycling performance can be attributed to the stable interface:The HTCN molecules with strong electron-donating ability participate in the construction of cathode-electrolyte interphase(CEI)through coordinating with Co ions,which suppresses the decomposition of electrolyte and improves the structural stability of LiCoO_(2)during *** summary,the work recognizes a coordinating-based interphase-forming mechanism as an effective strategy to optimize the performance of high voltage LiCoO_(2)cathode with appropriate electrolyte additives for practical pouch batteries.

关键词： LiCoO_(2) high voltage nitrile additive interface adsorption pouch cell electrolyte modification

Beneficial effects of a decreased meal frequency on nutrient utilization,secretion of luteinizing hormones and ovarian follicular development in gilts

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Journal of Animal Science and Biotechnology 2021年第3期12卷 1098-1111页

作者： Lun Hua Lianpeng Zhao Zhengyu Mao Wentao Li Jing Li Xuemei Jiang Lianqiang Che Shengyu Xu Yan Lin zhengfeng Fang Bin Feng De Wu Yong Zhuo Animal Nutrition Institute Sichuan Agricultural UniversityChengdu 611130People’s Republic of China Key Laboratory for Animal Disease-Resistant Nutrition of the Ministry of Education of China Sichuan Agricultural UniversityChengdu 611130People’s Republic of China Key Laboratory of Animal Disease-Resistant Nutrition of Sichuan Province Sichuan Agricultural University211 Huimin RoadWenjiang DistrictChengdu 611130People’s Republic of China

Background:Replacement gilts are typically fed ad libitum,whereas emerging evidence from human and rodent studies has revealed that time-restricted access to food has health *** objective of this study was to investigate the effect of meal frequency on the metabolic status and ovarian follicular development in ***:A total of 36 gilts(Landrace×Yorkshire)with an age of 150±3 d and a body weight of 77.6±3.8 kg were randomly allocated into one of three groups(n=12 in each group),and based on the group allocation,the gilts were fed at a frequency of one meal(T1),two meals(T2),or six meals per day(T6)for 14 consecutive *** effects of the meal frequency on growth preference,nutrient utilization,short-chain fatty acid production by gut microbial,the post-meal dynamics in the metabolic status,reproductive hormone secretions,and ovarian follicular development in the gilts were ***:The gilts in the T1 group presented a higher average daily gain(+48 g/d,P<0.05)and a higher body weight(+4.9 kg,P<0.05)than those in the T6 *** meal frequency had no effect on the apparent digestibility of dry matter,crude protein,ether extract,ash,and gross energy,with the exception that the T1 gilts exhibited a greater NDF digestibility than the T6 gilts(P<0.05).The nitrogen balance analysis revealed that the T1 gilts presented decreased urine excretion of nitrogen(−8.17 g/d,P<0.05)and higher nitrogen retention(+9.81 g/d,P<0.05),and thus exhibited higher nitrogen utilization than the T6 *** time-course dynamics of glucose,α-amino nitrogen,urea,lactate,and insulin levels in serum revealed that the T1 group exhibited higher utilization of nutrients after a meal than the T2 or T6 *** T1 gilts also had a higher acetate content and SCFAs in feces than the T6 gilts(P<0.05).The age,body weight and backfat thickness of the gilts at first estrous expression were not affected by the meal frequency,but the gilts in the T1 group had higher levels of seru

关键词： Gilts Luteinizing hormone Meal frequency Nutrient utilization Ovarian follicular development

Intracellular codelivery of anti-inflammatory drug and anti-miR 155 to treat inflammatory disease

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Acta Pharmaceutica Sinica B 2020年第8期10卷 1521-1533页

作者： Chao Teng Chenshi Lin Feifei Huang Xuyang Xing Shenyu Chen Ling Ye Helena S.Azevedo Chenjie Xu zhengfeng Wu Zhongjian Chen Wei He School of Pharmacy China Pharmaceutical UniversityNanjing 210009China School of Pharmaceutical Sciences Southern Medical UniversityGuangzhou 510515China School of Engineering and Materials Science Institute of BioengineeringUniversity of LondonLondon E14NSUK Department of Biomedical Engineering City University of Hong KongKowloonHong KongChina Key Laboratory of Modern Preparation of TCM Ministry of EducationJiangxi University of Traditional Chinese MedicineNanchang 330004China Shanghai Skin Disease Hospital Tongji University School of MedicineShanghai 200443China

Atherosclerosis(AS) is a lipid-driven chronic inflammatory disease occurring at the arterial subendothelial space. Macrophages play a critical role in the initiation and development of AS. Herein,targeted codelivery of anti-miR 155 and anti-inflammatory baicalein is exploited to polarize macrophages toward M2 phenotype, inhibit inflammation and treat AS. The codelivery system consists of a carrier-free strategy(drug-delivering-drug, DDD), fabricated by loading anti-miR155 on baicalein nanocrystals,named as baicalein nanorods(BNRs), followed by sialic acid coating to target macrophages. The codelivery system, with a diameter of 150 nm, enables efficient intracellular delivery of anti-miR155 and polarizes M1 to M2, while markedly lowers the level of inflammatory factors in vitro and in vivo. In particular, intracellular fate assay reveals that the codelivery system allows for sustained drug release over time after internalization. Moreover, due to prolonged blood circulation and improved accumulation at the AS plaque, the codelivery system significantly alleviates AS in animal model by increasing the artery lumen diameter, reducing blood pressure, promoting M2 polarization, inhibiting secretion of inflammatory factors and decreasing blood lipids. Taken together, the codelivery could potentially be used to treat vascular inflammation.

关键词： miR155 inflammatory sustained

Mammary cell proliferation and catabolism of adipose tissues in nutrition-restricted lactating sows were associated with extracellular high glutamate levels

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Journal of Animal Science and Biotechnology 2019年第1期10卷 172-182页

作者： Heju Zhong Peng Wang Yumo Song Xiaoling Zhang Lianqiang Che Bin Feng Yan Lin Shengyu Xu Jian Li De Wu Qiaofeng Wu zhengfeng Fang Key Laboratory for Animal Disease Resistance Nutrition of the Ministry of Education Animal Nutrition InstituteSichuan Agricultural University Acupuncture and Moxibustion College Chengdu University of Traditional Chinese Medicine

Background: Persistent lactation,as the result of mammary cellular anabolism and secreting function,is dependent on substantial mobilization or catabolism of body reserves under nutritional ***,little is known about the biochemical mechanisms for nutrition-restricted lactating animals to simultaneously maintain the anabolism of mammary cells while catabolism of body *** present study,lactating sows with restricted feed allowance(RFA)(n = 6),24% feed restriction compared with the control(CON) group(n = 6),were used as the nutrition-restricted *** and mammary venous cannulas methods were used to monitor postprandial dynamic changes of metabolites in adipose and mammary ***: At lactation d 28,the RFA group showed higher(P 0.05) between ***,piglet performance and milk yield did not differ(P > 0.05) between *** would appear that activation of Notch signaling and adequate supply of glutamate might assist ***: Mammary cell proliferation and catabolism of adipose tissues i

关键词： Glutamate Insulin sensitivity Lipolysis Mammary cell proliferation

Wide-spectrum polarization-sensitive and fast-response photodetector based on 2D group Ⅳ-Ⅵ semiconductor tin selenide

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Fundamental Research 2022年第6期2卷 985-992页

作者： Yali Yu Tao Xiong zhengfeng Guo Shijun Hou Juehan Yang Yue-Yang Liu Honggang Gu Zhongming Wei State Key Laboratory of Superlattices and Microstructures Institute of SemiconductorsChinese Academy of SciencesBeijing 100083China Center of Materials Science and Optoelectronic Engineering University of Chinese Academy of SciencesBeijing 100049China State Key Laboratory of Digital Manufacturing Equipment and Technology Huazhong University of Science and TechnologyWuhan 430074China

Tin selenide(SnSe)has attracted considerable interest recently on account of its low-symmetry lattice structure,great compatibility with key semiconductor technology,and remarkable electrical and optical ***-based polarization-sensitive photodetectors show promising application prospects because of their fast response and excellent photoelectric ***,an in-plane anisotropic SnSe nanosheet was synthesized and reported in detail by applying angle-resolved polarized Raman spectroscopy(ARPRS),polarization-resolved optical microscopy(PROM),angle-resolved optical absorption spectroscopy(AROAS),and other crystal structure characterization ***,SnSe crystals exhibit superior polarization detection performance with a high anisotropic photocurrent ratio(2.31 at 1064 nm)due to the structure formed by the Van der Waals superposition of covalently bonded atomic ***,SnSe-based photodetectors have high responsivity(9.27 A/W),high detectivity(4.08×10^(10)Jones),and fast response(in the order of nanoseconds).These results suggest a new method for fabricating 2D fast-response polarization-sensitive photodetectors in the future.

关键词： Layered SnSe In-plane anisotropy Polarization-sensitive photodetector Fast response Wide spectrum

Non-equilibrium between ions and electrons inside hot spots from National Ignition Facility experiments

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Matter and Radiation at Extremes 2017年第1期2卷 3-8页

作者： zhengfeng Fan Yuanyuan Liu Bin Liu Chengxin Yu Ke Lan Jie Liu Institute of Applied Physics and Computational Mathematics Beijing 100088China Center for Applied Physics and Technology Peking UniversityBeijing 100871China

The non-equilibrium between ions and electrons in the hot spot can relax the ignition conditions in inertial confinement fusion[Fan et al.,*** 23,010703(2016)],and obvious ion-electron non-equilibrium could be observed by our simulations of high-foot implosions when the ion-electron relaxation is enlarged by a factor of *** the other hand,in many shots of high-foot implosions on the National Ignition Facility,the observed X-ray enhancement factors due to ablator mixing into the hot spot are less than unity assuming electrons and ions have the same temperature[Meezan et al.,*** 22,062703(2015)],which is not self-consistent because it can lead to negative ablator mixing into the hot ***,this non-consistency implies ion-electron non-equilibrium within the hot *** our study,we can infer that ion-electron non-equilibrium exists in high-foot implosions and the ion temperature could be~9%larger than the equilibrium temperature in some NIF shots.

关键词： Ion-electron non-equilibrium Hot-spot ignition conditions relaxation High-foot experiments

C FLBER IS NOT IMPORTANT IN ACUPUNCTURE ANALGESIA BUT FOR DNIC

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针刺研究 1989年第Z1期 140-141页

作者： Bao Hong Zhou zhengfeng Yu yingxin Han Jisheng Department of Physiology, Beijing Medical University

A lot of work had been done to explore the mechanism of acupuncture anal-gesia (AA), but there have been some important questions to be dclarified. Forcxample, what kind of afferent fiber plays an important role in AA? In orderto solve this question, we applied capsaicin topically on sciatic nerve and usedthe techniques of extracellular recording and nerve trunk recording.

关键词： NH C FLBER IS NOT IMPORTANT IN ACUPUNCTURE ANALGESIA BUT FOR DNIC WDR

Analysis of the Topographic slope of the Moon Using Multiscale Spherical Spline Method

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Analysis of the Topographic slope of the Moon Using Multisca...