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Analysis of quality of life in patients after transgastric natural orifice transluminal endoscopic gallbladder-preserving surgery

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World Journal of Gastrointestinal Endoscopy 2024年第6期16卷 318-325页

作者： Min-yu Zhang Sen-yuan zheng zheng-yu ru Zhi-Qiang Zhang Department of Gastroenterology The First Affiliated Hospital of Xinjiang Medical UniversityUrimuqi 830011Xinjiang Uygur Autonomous RegionChina

BACKGROUND At present,laparoscopic cholecystectomy(LC)is the main surgical treatment for ***,after gallbladder removal,there are many ***,it is hoped to remove stones while preserving the function of the gallbladder,and with the development of endoscopic technology,natural orifice transluminal endoscopic surgery came into *** To compare the quality of life,perioperative indicators,adverse events after LC and transgastric natural orifice transluminal endoscopic gallbladder-preserving surgery(EGPS)in patients with *** Patients who were admitted to The First Affiliated Hospital of Xinjiang Medical University from 2020 to 2022 were retrospectively *** adopted propen-sity score matching(1:1)to compare EGPS and LC *** A total of 662 cases were collected,of which 589 cases underwent LC,and 73 cases underwent *** score matching was performed,and 40 patients were included in each of the *** the EGPS group,except the gastr-ointestinal defecation(P=0.603),the total score,physical well-being,mental well-being,and gastrointestinal digestion were statistically significant compared with the preoperative score after surgery(P<0.05).In the LC group,except the mental well-being,the total score,physical well-being,gastrointestinal digestion,the gastrointestinal defecation was statistically significant compared with the preoperative score after surgery(P<0.05).When comparing between groups,gastrointestinal defecation had significantly difference(P=0.002)between the two groups,there was no statistically significant difference in the total postoperative score and the other three *** the surgery duration,hospital stay and cost,LC group were lower than EGPS *** recurrence factors of gallstones after EGPS were analyzed:and recurrence was not correlated with gender,age,body mass index,number of stones,and preoperative *** Whether EGPS or LC,it can improve the patient’s symp

关键词： Gallstones Natural orifice transluminal endoscopic surgery Gallbladder preservation Cholecystolithotomy Laparoscopic cholecystectomy Gastrointestinal quality of life index

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五年制高职创新创业教育“四阶梯递进”课程体系研究

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扬州职业大学学报 2024年第3期28卷 52-55页

作者：刘厚林郑如玉江苏联合职业技术学院江苏扬州225002

目前五年制高职创新创业教育课程体系存在系统性不足、教学生态亟待完善、教育实践亟待加强、教育理念亟待提升和课程实施主体合作机制不完善等问题。基于此,构建了通识教育—专创融合—双创实践—项目实战的“四阶梯递进”创新创业教... 详细信息

目前五年制高职创新创业教育课程体系存在系统性不足、教学生态亟待完善、教育实践亟待加强、教育理念亟待提升和课程实施主体合作机制不完善等问题。基于此,构建了通识教育—专创融合—双创实践—项目实战的“四阶梯递进”创新创业教育课程体系。并从强化课程设计、确保多课程渗透、注重跨专业融合、坚持德技并修、推动校企政合作等方面提出“四阶梯递进”创新创业教育课程的实施策略。

关键词：五年制高职创新创业教育四阶梯递进课程体系构建

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Isolation and identification of Fusarium oxysporum f. sp. cubense in Fujian Province, China

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Journal of Integrative Agriculture 2019年第8期18卷 1905-1913页

作者： WU Kai-li CHEN Wei-zhong YANG Shuai WEN Ya zheng yu-ru Wilfred Mabeche Anjago yuN Ying-zi WANG Zong-hua State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops College of Plant Protection Fujian Agriculture and Forestry University Fuzhou 350002 P.R.China Fujian Institute for Food and Drug Quality Control Fuzhou 350001 P.R.China Institute of Oceanography Minjiang University Fuzhou 350108 P.R.China

Fusarium wilt, caused by Fusarium oxyporum f. sp. cubense(Foc), is the most serious disease affecting banana *** clarify the distribution of the Foc races in Fujian Province of China, 79 soil samples were collected from four regions of Zhangzhou City, the primary banana production area in Fujian. We isolated and identified 12 Foc strains based on internal transcribed spacer(ITS) sequence analysis, PCR amplification by using Foc-specific primers and pathogenicity *** analysis indicated that 11 isolates belong to Foc race 1, and 1 isolate belongs to the Foc tropical species race 4(TR4).Although TR4 has previously been reported to occur in primary banana-producing provinces, such as Hainan, Guangxi,and Guangdong of China, this is the first report of TR4 isolated from the soil in Fujian Province. Monitoring the presence of Foc, in particular, the TR4 strains in the soil, is the basic strategy to prevent and control Fusarium wilt.

关键词： Fusarium oxysporum f. sp. cubense(Foc) identification of physiological races pathogenicity test Fujian Fusarium wilt

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Research progress and prospect of low-carbon biological technology for nitrate removal in wastewater treatment

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Frontiers of Environmental Science & Engineering 2024年第7期18卷 1-21页

作者： ru zheng Kuo Zhang Lingrui Kong Sitong Liu College of Environmental Sciences and Engineering Peking UniversityBeijing 100871China Key Laboratory of Water and Sediment Sciences Ministry of Education of ChinaBeijing 100871China Eco-Environment and Resource Efficiency Research Laboratory School of Environment and EnergyPeking University Shenzhen Graduate SchoolShenzhen 518055China

Wastewater treatment plants are the major energy consumers and significant sources of greenhouse gas emissions,among which biological nitrogen removal of wastewater is an important contributor to carbon ***,traditional heterotrophic denitrification still has the problems of excessive residual sludge and the requirement of external carbon ***,the development of innovative low-carbon nitrate removal technologies is *** review outlines the key roles of sulfur autotrophic denitrification and hydrogen autotrophic denitrification in low-carbon wastewater *** discovered nitrate/nitrite dependent anaerobic methane oxidation enables sustainable methane emission reduction and nitrogen removal by utilizing available methane in *** microorganisms exhibited a promising potential to achieve carbon-negative nitrate ***,the algal-bacterial symbiosis system and photogranules offer effective and prospective low-carbon options for nitrogen ***,the emerging nitrate removal technology of photoelectrotrophic denitrification and the underlying,photoelectron transfer mechanisms are ***,we summarize and prospect these technologies,highlighting that solar-driven biological nitrogen removal technology is a promising area for future sustainable wastewater *** review has important guiding significance for the design of low-carbon wastewater treatment systems.

关键词： Carbon emissions Low-carbon Biological nitrogen removal Denitrification

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Efficacy of scraping therapy on blood pressure and sleep quality in stage Ⅰ and Ⅱ essential hypertension: A systematic review and meta-analysis

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Journal of Integrative Medicine 2024年第1期22卷 12-21页

作者： zheng-gang Zhu Jian-ru Wang Xiao-yan Pan School of Nursing Hunan University of Chinese MedicineChangsha 410208Hunan ProvinceChina School of Health Sciences Universiti Sains MalaysiaKubang Kerian 16150KelantanMalaysia Department of Cardiovascular Medicine the First Affiliated Hospital of Henan University of Chinese MedicineZhengzhou 450000Henan ProvinceChina

Background Scraping therapy is widely used in treating stage I and II essential hypertension in ***,there has been no systematic evaluation of the efficacy of scraping therapy on blood pressure and sleep quality in stage I and II essential *** strategy Seven electronic databases(PubMed,Scopus,Cochrane Library,Web of Science,EBSCO,China National Knowledge Infrastructure and Wanfang Data electronic databases)were searched from inception to December *** on the principle of combining subject words with text words,the search strategy was constructed around search terms for“scraping therapy,”“scraping,”“Guasha,”“Gua sha,”“hypertension,”and“high blood pressure”during the database *** criteria Randomized controlled trials(RCTs)were included if they recruited patients with stage I and II essential hypertension and included a scraping therapy *** intervention group received antihypertensive drugs and scraping therapy,while the control group only took antihypertensive *** extraction and analysis Review Manager 5.4.0 and STATA 15.1 were used to enter all the relevant outcome variables to conduct the *** quality of the selected RCTs was assessed using the PEDro *** sensitivity analysis was carried out by iteratively excluding individual studies and repeating the analysis to determine the stability of the findings and identify any studies with greater influence on the *** analysis was performed to find the source of *** plots were used to evaluate the publication bias of included *** Nine RCTs including 765 participants were ***-analysis showed that scraping therapy combined with medication had an advantage over the use of medication alone in lowering systolic blood pressure(mean difference[MD]=?5.09,95%confidence interval[CI]=?6.50 to?3.67,P<0.001)and diastolic blood pressure(MD=?2.66,95%CI=?3.17 to?2.14,P<0.001).Subgroup analysis showed tha

关键词： Scraping therapy Essential hypertension Efficacy Blood pressure Sleep quality Systematic review Meta-analysis

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Applications of genetic code expansion technology in eukaryotes

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Protein & Cell 2024年第5期15卷 331-363页

作者： Qiao-ru Guo yu J.Cao State Key Laboratory of Chemical Oncogenomic Guangdong Provincial Key Laboratory of Chemical GenomicsPeking University Shenzhen Graduate SchoolShenzhen 518055China Institute of Chemical Biology Shenzhen Bay LaboratoryShenzhen 518132China

Unnatural amino acids(UAAs)have gained significant attention in protein engineering and drug development owing to their ability to introduce new chemical functionalities to *** eukaryotes,genetic code expansion(GCE)enables the incorporation of UAAs and facilitates posttranscriptional modification(PTM),which is not feasible in prokaryotic *** is also a powerful tool for cell or animal imaging,the monitoring of protein interactions in target cells,drug development,and switch ***,there is keen interest in utilizing GCE in eukaryotic *** review provides an overview of the application of GCE in eukaryotic systems and discusses current challenges that need to be addressed.

关键词： genetic code expansion unnatural amino acid eukaryotes basic research therapeutic applications

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The Logarithmic Sobolev Inequality for a Submanifold in Manifolds with Nonnegative Sectional Curvature

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Chinese Annals of Mathematics,Series B 2024年第3期45卷 487-496页

作者： Chengyang YI yu zheng School of Mathematical Sciences East China Normal UniversityShanghai 200241China

The authors prove a sharp logarithmic Sobolev inequality which holds for compact submanifolds without boundary in Riemannian manifolds with nonnegative sectional curvature of arbitrary dimension and *** the Michael-Simon Sobolev inequality,this inequality includes a term involving the mean *** extends a recent result of Brendle with Euclidean setting.

关键词： Logarithmic Sobolev inequality Nonnegative sectional curvature Submanifold

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Effect of Guanxin Danshen Dripping Pills on Coronary Heart Disease Comorbid with Depression or Anxiety: The ADECODE-Real World Study

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Chinese Journal of Integrative Medicine 2024年第5期30卷 443-448页

作者： WU Shi-hao SHI Wei-qi LI yu-hang LIU ru-hui HU Da-yi zheng Li-qiang MA Wen-lin Department of Geriatric Medicine Tongji HospitalSchool of MedicineTongji UniversityShanghai 200065China Department of Cardiology Tongji HospitalSchool of MedicineTongji UniversityShanghai 200065China Department of Cardiology Peking University People's HospitalBeijing 100044China School of Public Health Shanghai Jiao Tong UniversityShanghai 200030China

Objective: To evaluate the efficacy of Guanxin Danshen Dripping Pill(GXDSDP) in treating anxiety and depression in patients with coronary heart disease(CHD). Methods: A total of 1,428 patients diagnosed with CHD screened for anxiety, depression, and quality of life(QOL) at baseline received 0.4 g of GXDSDP treatment 3 times per day and returned for monthly reassessment. Patients were recruited after stable treatment for CHD and received assessment of General Anxiety Disorder-7(GAD-7), Patient Health Questionnaire-9(PHQ-9), and Seattle Angina Questionnaire(SAQ) for evaluating anxiety, depression, and *** were followed up 3 times, once every 4 weeks, during outpatient visits for 12 weeks. Results: At the third follow-up(F3), the anxiety symptom of 63.79%(673/1,055) of the patients improved to sub-clinical level, and the GAD-7 score improved significantly(8.11 vs. 3.87, P<0.01);57.52%(585/1,017) patients' depressive symptoms improved to sub-clinical level, with a significant improvement in PHQ-9 score(8.69 vs. 4.41, P<0.01) at F3. All aspects of QOL significantly improved at the end of treatment compared to those at baseline(all P<0.01) as assessed by SAQ: physical limitation(31.17 vs. 34.14), anginal stability(2.74 vs. 4.14), anginal frequency(8.16vs. 9.10), treatment satisfaction(13.43 vs. 16.29), and disease perception(8.69 vs. 11.02). Conclusions: A fixed dosage of GXDSDP may be a potential treatment option for CHD patients comorbid with anxiety or depression.(Registration No. ChiCTR2100051523)

关键词： Guanxin Danshen Dripping Pill coronary heart disease depression anxiety quality of life Chinese medicine

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A Review on the Application of Deep Learning Methods in Detection and Identification of Rice Diseases and Pests

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Computers, Materials & Continua 2024年第1期78卷 197-225页

作者： Xiaozhong yu Jinhua zheng College of Computer Science and Technology Hengyang Normal UniversityHengyang421002China Hunan Provincial Key Laboratory of Intelligent Information Processing and Application Hengyang Normal UniversityHengyang421002China

In rice production,the prevention and management of pests and diseases have always received special *** methods require human experts,which is costly and *** to the complexity of the structure of rice diseases and pests,quickly and reliably recognizing and locating them is ***,deep learning technology has been employed to detect and identify rice diseases and *** paper introduces common publicly available datasets;summarizes the applications on rice diseases and pests from the aspects of image recognition,object detection,image segmentation,attention mechanism,and few-shot learning methods according to the network structure differences;and compares the performances of existing ***,the current issues and challenges are explored fromthe perspective of data acquisition,data processing,and application,providing possible solutions and *** study aims to review various DL models and provide improved insight into DL techniques and their cutting-edge progress in the prevention and management of rice diseases and pests.

关键词： Deep learning rice diseases and pests image recognition object detection

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Black hole evaporation and its remnants with the generalized uncertainty principle including a linear term

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Communications in Theoretical Physics 2024年第2期76卷 125-136页

作者： Bo yu zheng-wen Long College of Physics Guizhou UniversityGuiyang550025China

In recent years,researchers have investigated the evaporation of Schwarzschild black holes using various forms of the generalized uncertainty principle(GUP),metric quantum correction,and noncommutative geometry,***,there are differences between the GUP correction and the other two methods in terms of describing the later stages of black hole ***,some studies argue that the GUP with a negative parameter cannot effectively correct black hole evaporation,while others contend that the positivity or negativity of the GUP parameters should not affect the correction *** the above into consideration,we reconsider black hole evaporation with the generalized uncertainty principle including a linear term(LGUP),and examine the case of negative *** results indicate that the evaporation behavior of both Schwarzschild black holes and Reissner–Nordstr?m black holes,under LGUP correction,is consistent with the results of metric quantum correction and non-commutative ***,the negative parameter LGUP can also effectively correct for black hole evaporation.

关键词： black hole evaporation generalized uncertainty principle negative parameter

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