检索结果-南通市图书馆

Hepatobiliary & Pancreatic Diseases International 2024年第2期23卷 117-122页

作者： xin Yang Lu Lu Wen-Wei Zhu Yi-Feng Tao Cong-Huan Shen Jin-Hong Chen zheng-xin wang Lun-Xiu Qin Hepatobiliary Surgery and Liver Transplantation Centers Department of General SurgeryHuashan Hospital&Cancer Metastasis InstituteFudan UniversityShanghai 200040China

Hepatectomy is still the major curative treatment for patients with liver ***,it is still a big challenge to remove the tumors in the central posterior area,especially if their location involves the retrohepatic inferior vena cava and hepatic *** vivo liver resection and auto-transplantation(ELRA),a hybrid technique of the traditional liver resection and transplantation,has brought new hope to these patients and therefore becomes a valid alternative to liver *** to its technical difficulty,ELRA is still concentrated in a few hepatobiliary centers that have experienced surgeons in both liver resection and liver *** efficacy and safety of this technique has already been demonstrated in the treatment of benign liver diseases,especially in the advanced alveolar ***,the application of ELRA for liver malignances has gained more ***,standardization of clinical practice norms and international consensus are still *** prognostic impact in these oncologic patients also needs further *** this review,we summarized the principles and recent progresses on ELRA.

关键词： Ex vivo liver resection Liver auto-transplantation Oncology Liver malignancies

Liver transplantation due to cerebrotendinous xanthomatosis end-stage liver disease

在线全文

学校读者我要写书评

暂无评论

World Journal of Pediatrics 2018年第4期14卷 414-415页

作者： Cong-Huan Shen zheng-xin wang Department of General Surgery Affiliated Huashan Hospital of Fudan University796 Jiang Su RoadShanghai 200040China

Cerebrotendinous xanthomatosis (CTX) is an autosomal recessive disease characterized by an increase in plasma concentrations of cholestanol and storage of sterols in mul-tiple tissues, especially tendons and the nervous system (1)Neonatal cholestatic jaundice has been rarely reported, but patients may progress to cirrhosis if effective treatment is not provided. Mutations in theCYP27A1 gene leads to decreased synthesis of bile acid, excessive production of cholestanol, and consequent accumulation of cholestanol in tissues in patients with CTX (2)The liver is rarely affected in these patients;however, neonatal cholestatic jaundice can be self-limiting. Reports on liver transplantation for CTX are lacking. Liver transplantation not only cures the liver disease, but also introduces the normalCYP27A1 gene into the patient, which can be potentially beneficial.

关键词： Liver transplantation cerebrotendinous xanthomatosis end-stage liver disease

Effects of V and Zr Additions on Microstructures and Mechanical Properties of Nb-Ti-Al-Base Alloys

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

稀有金属材料与工程 2009年第A3期38卷 5-7页

作者： Bai Run zheng xin Li Zhongkui wang Donghui Xia Mingxing Northwest Institute for Nonferrous Metal Research Xi＇an 710016 China

Microstructures and mechanical properties of Nb-32Ti-7Al alloys containing different V and Zr contents were investigated. The microstructures were characterized using optical microscopy and scanning electron microscopy (SEM). The alloy with V and Zr presents single phase Nb solid solution (Nbss). Tensile testing was carried out at room temperature and 1373 K. The results show that these alloys have good ductility at room temperature. The strengths at room and high temperature increase with the addition of V and Zr, but the room temperature ductility decrease.

关键词：力学性能光学显微镜铌扫描电子显微镜

物流仓库无线传感网络与自动巡检小车监测系统设计

在线全文

学校读者我要写书评

暂无评论

菏泽学院学报 2024年第2期46卷 25-30页

作者：杨延丽郑新旺杨光松集美大学诚毅学院福建厦门361021 集美大学信息工程学院福建厦门361021

针对物流仓库潜在的安全隐患问题,设计了Zigbee无线传感网络和自动巡检智能小车相结合的仓库监测系统.首先使用多个Zigbee终端节点连接环境参数传感器套件,分布到仓库货架上实现静态监测;其次,设计了自动循迹智能小车搭载热像仪和传感... 详细信息

针对物流仓库潜在的安全隐患问题,设计了Zigbee无线传感网络和自动巡检智能小车相结合的仓库监测系统.首先使用多个Zigbee终端节点连接环境参数传感器套件,分布到仓库货架上实现静态监测;其次,设计了自动循迹智能小车搭载热像仪和传感器实现仓库环境动态监测.通过增量式PID对电机进行闭环控制,使小车的速度和转向角度沿着预定路径前进.经测试,该系统可以实现物流仓库静态和动态全方位监测和及时预警,为保障仓库安全提供了一种技术管理手段.

关键词： Zigbee 自动巡检巡检小车热像仪安全管理

Surface Modification With Zinc and Zn-Ni Alloy Compositionally Modulated Multilayer Coatings

在线全文

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2006年第4期13卷 61-67页

作者： FEI Jing-yin LIANG Guo-zheng xin Wen-li wang Wei-kang Department of Applied Chemistry Northwestern Polytechnical University Xi＇an 710072 Shaanxi China

Zinc and Zn-Ni alloy compositionally modulated multilayer （CMM） coatings were electrodeposited on to a steel substrate by the successive deposition of zinc and Zn-Ni alloy sublayers from dual baths. The coated samples were evaluated in terms of the surface appearance, surface and cross-sectional morphologies, as well as corrosion resistance. The microstructural characteristics that were examined using the field emission gun scanning electron microscopy （FEGSEM） confirmed the layered structure, grain refinement of the zinc and Zn-Ni alloy CMM coatings, and revealed the existence of microcracks caused by the internal stress in the thick Zn-Ni alloy sublayers. The corrosion resistance that was evaluated by means of the salt spray test shows that the zinc and Zn-Ni alloy CMM coatings were more corrosion-resistant than the monolithic coatings of zinc or Zn-Ni alloy of the same thickness. The possible reasons for the better protective performance of Zn-Ni/Zn CMM coatings were given on the basis of the analysis on the micrographic features of zinc and Zn-Ni alloy CMM eoatings after the corrosion test. A probable corrosion mechanism of zinc and Zn-Ni alloy CMM coatings was also proposed.

关键词： electrodeposition compositionally modulated multilayer coating Zn-Ni alloy corrosion resistance

Diabetes mellitus is a risk factor of acute kidney injury in liver transplantation patients

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2021年第3期20卷 215-221页

作者： Yu-Jia wang Jian-Hua Li Yi Guan Qiong-Hong Xie Chuan-Ming Hao zheng-xin wang Division of Nephrology Huashan HospitalFudan UniversityShanghai 200040China Division of General Surgery Huashan HospitalFudan UniversityShanghai 200040China

Background: Diabetes mellitus has become an increasing global health burden with rapid growing prevalence. Patients with diabetes have higher susceptibility to acute kidney injury(AKI). Liver transplantation(LT) predisposes the kidney to injury. However, the association between diabetes and AKI in LT patients remains unclear. Methods: We conducted a retrospective cohort study examining risk factors for AKI in patients undergone orthotopic LT. Potential risk factors including baseline estimated glomerular filtration rate(e GFR), the model for end-stage liver disease(MELD) score, diabetes, hypertension and intraoperative blood loss were screened. The primary endpoint was AKI occurrence. Multivariate logistic regression was used to analyze the association between potential risk factors and AKI. Results: A total of 291 patients undergone orthotopic LT were included in the present study. Among them, 102 patients(35.05%) developed AKI within 5 days after LT. Diabetes was identified as an independent risk factor for AKI. Patients who developed AKI had worse graft function recovery and higher mortality within 14 days after LT compared to those who did not develop AKI. AKI patients with diabetes had a significant decline of e GFR within the first postoperative year, compared with patients who did not develop AKI and who developed AKI but without diabetes. Conclusions: Diabetes is an independent risk factor for AKI after orthotopic LT. AKI is associated with delayed graft function recovery and higher mortality in short-term postoperative period. Diabetic patients who developed AKI after LT experience a faster decline of e GFR within the first year after surgery.

关键词： Acute kidney injury Liver transplantation Diabetes Renal function

Immune evasion mechanisms and therapeutic strategies in gastric cancer

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2022年第1期14卷 216-229页

作者： En-Si Ma zheng-xin wang Meng-Qi Zhu Jing Zhao Department of General Surgery Huashan HospitalFudan UniversityShanghai 200040China Institute of Organ Transplantation Fudan UniversityShanghai 200040China Department of Infectious Diseases Huashan HospitalFudan UniversityShanghai 200040China Cancer Metastasis Institute Fudan UniversityShanghai 200040China

Gastric cancer(GC)is a malignancy with a high incidence and *** tumor immune microenvironment plays an important role in promoting cancer development and supports GC *** evidence shows that GC cells can exert versatile mechanisms to remodel the tumor immune microenvironment and induce immune *** this review,we systematically summarize the intricate crosstalk between GC cells and immune cells,including tumor-associated macrophages,neutrophils,myeloid-derived suppressor cells,natural killer cells,effector T cells,regulatory T cells,and B *** focus on how GC cells alter these immune cells to create an immunosuppressive microenvironment that protects GC cells from immune *** conclude by compiling the latest progression of immune checkpoint inhibitor-based immunotherapies,both alone and in combination with conventional ***-cytotoxic Tlymphocyte-associated protein 4 and anti-programmed cell death protein 1/programmed death-ligand 1 therapy alone does not provide substantial clinical benefit for GC ***,the combination of immune checkpoint inhibitors with chemotherapy or targeted therapy has promising survival advantages in refractory and advanced GC *** review provides a comprehensive understanding of the immune evasion mechanisms of GC,and highlights promising immunotherapeutic strategies.

关键词： Gastric cancer Immune evasion Immune checkpoint Immunotherapy Microenvironment

12.6μm-Thick Asymmetric Composite Electrolyte with Superior Interfacial Stability for Solid-State Lithium-Metal Batteries

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano-Micro Letters 2024年第9期16卷 397-409页

作者： zheng Zhang Jingren Gou Kaixuan Cui xin Zhang Yujian Yao Suqing wang Haihui wang Beijing Key Laboratory for Membrane Materials and Engineering Department of Chemical EngineeringTsinghua UniversityBeijing 100084People’s Republic of China School of Chemistry and Chemical Engineering South China University of TechnologyGuangzhou 510000People’s Republic of China

Solid-state lithium metal batteries(SSLMBs)show great promise in terms of high-energy-density and high-safety ***,there is an urgent need to address the compatibility of electrolytes with high-voltage cathodes/Li anodes,and to minimize the electrolyte thickness to achieve highenergy-density of ***,we develop an ultrathin(12.6μm)asymmetric composite solid-state electrolyte with ultralight areal density(1.69 mg cm^(−2))for *** electrolyte combining a garnet(LLZO)layer and a metal organic framework(MOF)layer,which are fabricated on both sides of the polyethylene(PE)separator separately by tape *** PE separator endows the electrolyte with flexibility and excellent mechanical *** LLZO layer on the cathode side ensures high chemical stability at high *** MOF layer on the anode side achieves a stable electric field and uniform Li flux,thus promoting uniform Li^(+)*** to the well-designed structure,the Li symmetric battery exhibits an ultralong cycle life(5000 h),and high-voltage SSLMBs achieve stable cycle *** assembled pouch cells provided a gravimetric/volume energy density of 344.0 Wh kg^(−1)/773.1 Wh L^(−1).This simple operation allows for large-scale preparation,and the design concept of ultrathin asymmetric structure also reveals the future development direction of SSLMBs.

关键词： Solid-state lithium metal batteries Composite solid-state electrolyte Ultrathin asymmetric structure Pouch cells

Recent progress on mechanisms,principles,and strategies for high-activity and high-stability non-PGM fuel cell catalyst design

在线全文

学校读者我要写书评

暂无评论

Carbon Energy 2024年第5期6卷 25-52页

作者： Yuping Yuan Yun zheng Dan Luo Weibin Qiu Jiantao wang xin wang Zhongwei Chen GRINM(Guangdong)Institute of New Materials Technology FoshanChina Department of Chemical Engineering Waterloo Institute for NanotechnologyWaterloo Institute for Sustainable EnergyUniversity of WaterlooWaterlooOntarioCanada Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and Devices School of Information and Optoelectronic Science and EngineeringSouth China Normal UniversityGuangdongChina National Power Battery Innovation Center GRINM Group Co.Ltd.BeijingChina

The commercialization of a polymer membrane H2-O2 fuel cell and its widespread use call for the development of cost-effective oxygen reduction reaction(ORR)nonplatinum group metal(NPGM)***,to meet the requests for the real-world fuel cell application and replacing platinum catalysts,it still needs to address some challenges for NPGM catalysts regarding the sluggish ORR kinetics in the cathode and their poor durability in acidic *** response to these issues,numerous efforts have been made to study NPGM catalysts both theoretically and experimentally,developed these into the atomically dispersed coordinated metal-nitrogen-carbon(M-N-C)form over the past *** this review,we present a comprehensive summary of recent advancements on NPGM catalysts with high activity and *** design strategies in terms of optimizing active-site density and enhancing catalyst stability against demetalization and carbon corrosion are *** is also emphasized the importance of understanding the mechanisms and principles behind those strategies through a combination of theoretical modeling and experimental ***,further understanding the mechanisms related to the active-site structure and the formation process of the single-atom active site under pyrolysis conditions is critical for active-site *** the active-site distance is the basic principle for improving catalyst activity through increasing the catalyst active-site *** studies for the catalyst deactivation mechanism and modeling stable active-site structures provide both mechanisms and principles to improve the NPGM catalyst ***,currently remained challenges and perspectives in the future on designing high-performance atomically dispersed NPGM catalysts toward fuel cell application are discussed.

关键词： batteries electrocatalysis energy storage and conversion fuel cells

Sinusoidal obstruction syndrome related to tacrolimus following liver transplantation

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2020年第3期19卷 299-302页

作者： Li Li Yue Dong Rui-Dong Li Yi-Feng Tao Cong-Huan Shen zheng-xin wang Department of General Surgery Huashan HospitalFudan University12 Middle Urumqi RoadShanghai 200040China Institute of Organ Transplantation Fudan UniversityShanghai 200040China Department of Pharmacy Huashan HospitalFudan UniversityShanghai 200040China

To the Editor:Sinusoidal obstruction syndrome(SOS),also known as venoocclusive disease,is characterized by fibrotic occlusion of small hepatic veins and congestion of sinusoids[1].This syndrome is mainly observed in hematopoietic stem cell transplantation(HSCT)and its incidence in liver transplantation(LT)ranges from 1.9%to 2.9%[2,3].Although rare,severe SOS following LT can cause liver graft dysfunction with poor prognosis[3].

关键词： Sinus obstruction liver