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Visual attention network

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Computational Visual Media 2023年第4期9卷 733-752页

作者： Meng-Hao Guo Cheng-Ze Lu zheng-ning liu Ming-Ming Cheng Shi-Min Hu Department of Computer Science Tsinghua UniversityBeijingChina Nankai University TianjinChina Fitten Tech BeijingChina

While originally designed for natural language processing tasks,the self-attention mechanism has recently taken various computer vision areas by ***,the 2D nature of images brings three challenges for applying self-attention in computer vision:(1)treating images as 1D sequences neglects their 2D structures;(2)the quadratic complexity is too expensive for high-resolution images;(3)it only captures spatial adaptability but ignores channel *** this paper,we propose a novel linear attention named large kernel attention(LKA)to enable self-adaptive and long-range correlations in self-attention while avoiding its ***,we present a neural network based on LKA,namely Visual Attention Network(VAN).While extremely simple,VAN achieves comparable results with similar size convolutional neural networks(CNNs)and vision transformers(ViTs)in various tasks,including image classification,object detection,semantic segmentation,panoptic segmentation,pose estimation,*** example,VAN-B6 achieves 87.8%accuracy on ImageNet benchmark,and sets new state-of-the-art performance(58.2%PQ)for panoptic ***,VAN-B2 surpasses Swin-T 4%mloU(50.1%vs.46.1%)for semantic segmentation on ADE20K benchmark,2.6%AP(48.8%vs.46.2%)for object detection on COCO *** provides a novel method and a simple yet strong baseline for the *** code is available at https://***/Visual-Attention-Network.

关键词： vision backbone deep learning ConvNets attention

Can attention enable MLPs to catch up with CNNs?

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Computational Visual Media 2021年第3期7卷 283-288页

作者： Meng-Hao Guo zheng-ning liu Tai-Jiang Mu Dun Liang Ralph R.Martin Shi-Min Hu BNRist Department of Computer Science and TechnologyTsinghua UniversityBeijing 100084China Cardiff University Cardiff CF243AAUK.

In the first week of May 2021,researchers from four different institutions:Google,Tsinghua University,Oxford University,and Facebook shared their latest work[1–4]on ar *** at almost the same time,each proposing new learning architectures,consisting mainly of linear layers,claiming them to be comparable or superior to convolutional-based models.

关键词： enable Facebook Google

PCT:Point cloud transformer

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Computational Visual Media 2021年第2期7卷 187-199页

作者： Meng-Hao Guo Jun-Xiong Cai zheng-ning liu Tai-Jiang Mu Ralph R.Martin Shi-Min Hu BNRist Department of Computer Science and TechnologyTsinghua UniversityBeiing 100084China Cardiff University Cardiff CF243

The irregular domain and lack of ordering make it challenging to design deep neural networks for point cloud *** paper presents a novel framework named Point Cloud Transformer(PCT)for point cloud *** is based on Transformer,which achieves huge success in natural language processing and displays great potential in image *** is inherently permutation invariant for processing a sequence of points,making it well-suited for point cloud *** better capture local context within the point cloud,we enhance input embedding with the support of farthest point sampling and nearest neighbor *** experiments demonstrate that the PCT achieves the state-of-the-art performance on shape classification,part segmentation,semantic segmentation,and normal estimation tasks.

关键词： 3D computer vision deep learning point cloud processing Transformer

Attention mechanisms in computer vision:A survey

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Computational Visual Media 2022年第3期8卷 331-368页

作者： Meng-Hao Guo Tian-Xing Xu Jiang-Jiang liu zheng-ning liu Peng-Tao Jiang Tai-Jiang Mu Song-Hai Zhang Ralph R.Martin Ming-Ming Cheng Shi-Min Hu BNRist Department of Computer Science and TechnologyTsinghua UniversityBeijing 100084China TKLNDST College of Computer ScienceNankai UniversityTianjin 300350China School of Computer Science and Informatics Cardiff UniversityCardiffUK

Humans can naturally and effectively find salient regions in complex *** by this observation,attention mechanisms were introduced into computer vision with the aim of imitating this aspect of the human visual *** an attention mechanism can be regarded as a dynamic weight adjustment process based on features of the input *** mechanisms have achieved great success in many visual tasks,including image classification,object detection,semantic segmentation,video understanding,image generation,3D vision,multimodal tasks,and self-supervised *** this survey,we provide a comprehensive review of various attention mechanisms in computer vision and categorize them according to approach,such as channel attention,spatial attention,temporal attention,and branch attention;a related repository https://***/MenghaoG uo/Awesome-Vision-Attentions is dedicated to collecting related *** also suggest future directions for attention mechanism research.

关键词： attention transformer computer vision deep learning salience

Visualization of the protective role of estrogen against female liver fibrosis via an ER viscosity NIR fluorescent probe

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Science China Chemistry 2025年第1期 360-368页

作者： zheng liu Changyu Zhang Zipeng Li Wanying Ma Jia liu Xiang Xia ning Xu Wen Sun Jianjun Du Jiangli Fan Xiaojun Peng State Key Laboratory of Fine Chemicals Dalian University of Technology ningbo Institute of Dalian University of Technology

Endoplasmic reticulum(ER) viscosity has emerged as a new potential biomarker for hepatic fibrosis(HF). Herein, we report the first ER-targeting viscosity-responsive near-infrared(NIR) fluorescent probe HBT-PP for investigations of HF *** twisted intramolecular charge transfer(TICT) and the excited state intramolecular proton transfer(ESIPT) are combined to endow HBT-PP with the selective response towards viscosity(～62-fold) and a super large stokes shift(～320 nm). HBT-PP mainly targets organelle ER and is able to image the drug-or alcohol-induced viscosity elevation in living cells. Significantly,HBT-PP was successfully applied to visualize the gender difference in HF and the protective role of estrogen in restraining HF progression. Of note, after 10 min of stain with HBT-PP, HF lesions showed a stage-based response, indicating the potential of this probe in fast and early diagnosis of HF. These results clearly demonstrated the promising application of HBT-PP as a new tool for exploring ER viscosity-involved physiological and pathological processes.

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Interconnections between diabetic corneal neuropathy and diabetic retinopathy:diagnostic and therapeutic implications

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Neural Regeneration Research 2025年第8期20卷 2169-2180页

作者： Mingyi Yu Faith Teo En ning Chang liu Yu-Chi liu Tissue Engineering and Stem Cell Group Singapore Eye Research InstituteSingapore Yong Loo Lin School of Medicine National University of SingaporeSingapore Department of Cornea and External Eye Disease Singapore National Eye CenterSingapore Ophthalmology and Visual Sciences Academic Clinical Program Duke-NUS Medical SchoolSingapore

Diabetic corneal neuropathy and diabetic retinopathy are ocular complications occurring in the context of diabetes *** corneal neuropathy refers to the progressive damage of corneal *** retinopathy has traditionally been considered as damage to the retinal ***,growing evidence suggests that diabetic retinopathy is a complex neurovascular disorder resulting from dysfunction of the neurovascular unit,which includes both the retinal vascular structures and neural *** retinopathy is one of the leading causes of blindness and is frequently screened for as part of diabetic ocular ***,diabetic corneal neuropathy is commonly overlooked and underdiagnosed,leading to severe ocular surface *** studies have found that these two conditions tend to occur together,and they share similarities in their pathogenesis pathways,being triggered by a status of chronic *** review aims to discuss the interconnection between diabetic corneal neuropathy and diabetic retinopathy,whether diabetic corneal neuropathy precedes diabetic retinopathy,as well as the relation between the stage of diabetic retinopathy and the severity of corneal *** also endeavor to explore the relevance of a corneal screening in diabetic eyes and the possibility of using corneal nerve measurements to monitor the progression of diabetic retinopathy.

关键词： cornea corneal nerves diabetes diabetic corneal neuropathy diabetic retinopathy retina

The role of axon guidance molecules in the pathogenesis of epilepsy

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Neural Regeneration Research 2025年第5期20卷 1244-1257页

作者： zheng liu Chunhua Pan Hao Huang Department of Neurology Affiliated Hospital of Zunyi Medical UniversityZunyiGuizhou ProvinceChina

Current treatments for epilepsy can only manage the symptoms of the condition but cannot alter the initial onset or halt the progression of the disease. Consequently, it is crucial to identify drugs that can target novel cellular and molecular mechanisms and mechanisms of action. Increasing evidence suggests that axon guidance molecules play a role in the structural and functional modifications of neural networks and that the dysregulation of these molecules is associated with epilepsy susceptibility. In this review, we discuss the essential role of axon guidance molecules in neuronal activity in patients with epilepsy as well as the impact of these molecules on synaptic plasticity and brain tissue remodeling. Furthermore, we examine the relationship between axon guidance molecules and neuroinflammation, as well as the structural changes in specific brain regions that contribute to the development of epilepsy. Ample evidence indicates that axon guidance molecules, including semaphorins and ephrins, play a fundamental role in guiding axon growth and the establishment of synaptic connections. Deviations in their expression or function can disrupt neuronal connections, ultimately leading to epileptic seizures. The remodeling of neural networks is a significant characteristic of epilepsy, with axon guidance molecules playing a role in the dynamic reorganization of neural circuits. This, in turn, affects synapse formation and elimination. Dysregulation of these molecules can upset the delicate balance between excitation and inhibition within a neural network, thereby increasing the risk of overexcitation and the development of epilepsy. Inflammatory signals can regulate the expression and function of axon guidance molecules, thus influencing axonal growth, axon orientation, and synaptic plasticity. The dysregulation of neuroinflammation can intensify neuronal dysfunction and contribute to the occurrence of epilepsy. This review delves into the mechanisms associated with

关键词： axon guidance drug-resistant epilepsy epilepsy nerve regeneration nervous system diseases neural pathways neuroinflammatory diseases neuronal plasticity neurons synaptic remodeling

Sine oculis homeobox homolog family function in gastrointestinal cancer:Progression and comprehensive analysis

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World Journal of Clinical Oncology 2025年第1期16卷 10-24页

作者： Yang-zheng Lan zheng Wu Wen-Jia Chen Xin-ning Yu Hua-Tao Wu Jing liu Department of The Breast Center Cancer Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina Department of General Surgery First Affiliated Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina

The sine oculis homeobox homolog(SIX)family,a group of transcription factors characterized by a conserved DNA-binding homology domain,plays a critical role in orchestrating embryonic development and organogenesis across various organisms,including *** six distinct members,from SIX1 to SIX6,each member contributes uniquely to the development and differentiation of diverse tissues and organs,underscoring the versatility of the SIX *** or mutations in SIX genes have been implicated in a spectrum of developmental disorders,as well as in tumor initiation and progression,highlighting their pivotal role in maintaining normal developmental trajectories and cellular *** to target the transcriptional complex of the SIX gene family have emerged as a promising strategy to inhibit tumor *** the development of inhibitors targeting this gene family is still in its early stages,the significant potential of such interventions holds promise for future therapeutic ***,this review aimed to comprehensively explore the advancements in understanding the SIX family within gastrointestinal cancers,focusing on its critical role in normal organ development and its implications in gastrointestinal cancers,including gastric,pancreatic,colorectal cancer,and hepatocellular *** conclusion,this review deepened the understanding of the functional roles of the SIX family and explored the potential of utilizing this gene family for the diagnosis,prognosis,and treatment of gastrointestinal cancers.

关键词： Sine oculis homeobox homolog Gastrointestinal cancer Transcription factor Development Regulation Diagnosis Therapeutics

Multi boron-doping effects in hard carbon toward enhanced sodium ion storage

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Journal of Energy Chemistry 2025年第1期100卷 730-738页

作者： Peng zheng Wang Zhou Ying Mo Biao zheng Miaomiao Han Qin Zhong Wenwen Yang Peng Gao Lezhi Yang Jilei liu College of Materials Science and Engineering Hunan Joint International Laboratory of Advanced Materials and Technology for Clean Energy Hunan Province Key Laboratory for Advanced Carbon Materials and Applied Technology Hunan University Greater Bay Area Institute for Innovation Hunan University Changsha Research Institute of Mining & Metallurgy Co. LTD.

Hard carbon （HC） has been considered as promising anode material for sodium-ion batteries （SIBs）.The optimization of hard carbon’s microstructure and solid electrolyte interface （SEI） property are demonstrated effective in enhancing the Na+storage capability,however,a one-step regulation strategy to achieve simultaneous multi-scale structures optimization is highly ***,we have systematically investigated the effects of boron doping on hard carbon’s microstructure and interface chemistry.A variety of structure characterizations show that appropriate amount of boron doping can increase the size of closed pores via rearrangement of carbon layers with improved graphitization degree,which provides more Na+storage ***-situ Fourier transform infrared spectroscopy/electrochemical impedance spectroscopy （FTIR/EIS） and X-ray photoelectron spectroscopy （XPS） analysis demonstrate the presence of more BC3and less B–C–O structures that result in enhanced ion diffusion kinetics and the formation of inorganic rich and robust SEI,which leads to facilitated charge transfer and excellent rate *** a result,the hard carbon anode with optimized boron doping content exhibits enhanced rate and cycling *** general,this work unravels the critical role of boron doping in optimizing the pore structure,interface chemistry and diffusion kinetics of hard carbon,which enables rational design of sodium-ion battery anode with enhanced Na+storage performance.

关键词： X ray photoelectron spectroscopy