检索结果-南通市图书馆

Distinct distribution revealing multiple bacterial sources for 1-Omonoalkyl glycerol ethers in terrestrial and lake environments

在线全文

学校读者我要写书评

暂无评论

Science China Earth Sciences 2015年第6期58卷 1005-1017页

作者： YANG huan zheng FengFeng XIAO WenJie XIE ShuCheng State Key Laboratory of Biogeology and Environmental Geology China University of Geosciences State Key Laboratory of Marine Geology Tongji University

The 1-O-monoalkyl glycerol ethers （MAGEs） were initially viewed as the biomarkers for sulfate-reducing bacteria （SRB） me- diating anaerobic oxidation of methane in the marine environments. However, limited information is known about their distri- bution in terrestrial and other aquatic settings including soils, fresh water lakes, and cave sediments, which may obscure our understanding of their biological sources. Here we found that MAGEs were ubiquitous but differed obviously in distributional pattern among those environments. The surface soils are dominated generally by iC15：0-MAGE, followed by nCI6：o-MAGE whereas the lake sediments show the opposite, resulting in significantly higher iC15：0/nC16：0 ratios in soils than in lake sedi- ments. The cave deposits are characterized by considerably higher proportions of branched MAGEs than the former two envi- ronments. The logarithm of iC15：0/aC15：0 ratio shows a significant negative correlation with soil pH, likely reflecting an adapta- tion of microbial cell membrane to change in the ambient proton concentration. The MAGE profiles in cultured bacteria cannot fully explain the MAGE distribution in all the samples analyzed. Therefore, MAGEs in soil, lake sediments, and cave deposits likely have additional biological source（s） other than SRB and cultured MAGE-producing bacteria. The difference in MAGE pattern among environments is likely to be attributed to change in microbial communities.

关键词： 1-O-monoalkyl glycerol ethers soil lake sediments cave deposits biological sources

Studying the Fermi GeV light curve of Vela with the two-pole caustic model

在线全文

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2009年第12期9卷 1324-1330页

作者： huan Yu Jun fang Ze-Jun Jiang Department of Physics Yunnan University Kunming 650091 China

An observation of the Vela pulsar with the Fermi Large Area Telescope has been recently reported and the GeV light curve shows two main peaks with a phase separation of ～0.43. We study the GeV light curve using the two-pole caustic model in which the peaks of the light curves of the pulsar result from caustic effects. The results show that the two-pole caustic model can reproduce the observed emission pattern of the two peaks and the bridge emission between them well, but overestimates the flux outside the two peaks. After taking account of the pair production effect on the azimuthal angle, we find that the resulting light curve is more consistent with the observation. We excluded the emissions from the field lines for which the distance from the null charge surface, where the pairs can be significantly produced, is larger than the radius of the light cylinder.

关键词： gamma rays: theory -- pulsars: individual (PSR B0833-45)

左西孟旦联合膈肌电刺激对困难脱机风险患者的临床疗效

在线全文

学校读者我要写书评

暂无评论

中国医学创新 2025年第1期22卷 35-38页

作者：关欢曹猛方景云赣州市人民医院急诊科江西赣州341000

目的:观察左西孟旦联合膈肌电刺激对困难脱机风险患者的临床疗效。方法:选择2021年12月—2023年12月于赣州市人民医院就诊的困难脱机风险患者92例,采用随机数字表法将其分成常规组(n=46)与观察组(n=46)。常规组接受膈肌电刺激治疗,观察... 详细信息

目的:观察左西孟旦联合膈肌电刺激对困难脱机风险患者的临床疗效。方法:选择2021年12月—2023年12月于赣州市人民医院就诊的困难脱机风险患者92例,采用随机数字表法将其分成常规组(n=46)与观察组(n=46)。常规组接受膈肌电刺激治疗,观察组在常规组的基础上接受左西孟旦治疗。比较两组ICU住院时间、呼吸机使用时长、脱机相关指标、炎症因子及脱机成功率。结果:观察组ICU住院时间、呼吸机使用时长均短于常规组(P0.05);治疗48 h后,两组N末端B型利钠肽原(NT-proBNP)水平均降低,且观察组较常规组低,氧合指数均升高,且观察组较常规组高,差异均有统计学意义(P0.05);两组治疗48 h后的IL-6、TNF-α均降低,观察组均较常规组低(P<0.05)。观察组脱机成功率高于常规组,差异有统计学意义(P<0.05)。结论:左西孟旦联合膈肌电刺激应用于困难脱机风险患者,可缩短ICU住院时间、呼吸机使用时长,减轻炎症反应,调节氧合指数、NT-proBNP水平,提高脱机成功率。

关键词：膈肌电刺激左西孟旦困难脱机脱机成功率

Pleural effusion in an immunocompetent host with cryptococcal pneumonia:A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2020年第7期8卷 1295-1300页

作者： huan-huan Wu Yan-Xiao Chen Shuang-Yan fang Department of Respiratory Medicine Dongyang Hospital Affiliated to Wenzhou Medical UniversityDongyang 322100Zhejiang ProvinceChina Department of Evidence-base Medicine Dongyang Hospital Affiliated to Wenzhou Medical UniversityDongyang 322100Zhejiang ProvinceChina

BACKGROUND Pulmonary cryptococcosis is an opportunistic infection that mainly occurs among immunocompromised patients although it can sometimes occur in immunocompetent ***,the imaging findings of pulmonary cryptococcosis in immunocompetent hosts differ from those in immunosuppressed *** addition,the most common imaging findings of isolated pulmonary cryptococcosis are single or multiple *** and the halo sign are,however,prevalent in immunosuppressed *** immunocompetent patients,lung consolidation,pleural effusion or cavities are *** SUMMARY A 29-year-old Asian male was admitted to our hospital with complaints of cough and fever that had persisted for a *** a chest computed tomography scan showed consolidation in his left lower lobe,he was initially diagnosed with pneumonia and received antibiotic treatment.A second review of the chest computed tomography image revealed multiple cavities and pleural *** fiberoptic bronchoscopy was subsequently performed,bronchoalveolar lavage fluid and serum cryptococcal antigen tests were *** capsules were observed in bronchoalveolar lavage fluid ink *** examination of a percutaneous lung biopsy from the left lower lobe further revealed granulomatous inflammation,and periodic acid-Schiff staining showed red-colored yeast walls,signifying pulmonary *** patient was then treated with a daily dose of fluconazole(0.4 g),but the cough and fever still *** therefore changed treatment to voriconazole(0.2 g,twice a day),and the patient’s clinical outcome was *** Although rare,clinicians should not disregard the possibility of cavities and pleural effusion occurring in immunocompetent hosts without underlying diseases.

关键词： Pulmonary cryptococcosis Immunocompetent Computed tomography Pleural effusion Imaging findings Case report

A Note on Equilibrium of Eventually Strongly Monotone Skew-product Semiflows

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Mathematicae Applicatae Sinica 2010年第2期26卷 307-310页

作者： Xi-liang Li Zuo-huan zheng Shandong Institute of Business and Technology Yantai 264005 China Institute of Applied Mathematics Academy of Mathematics and Systems Science Chinese Academy of SciencesBeijing 100190 China

In this paper, we show that for an eventually strongly monotone skew-product semiflow τ, the strict ordering on Ec （the set consisting of continuous equilibria of τ） implies the strong one.

关键词： continuous equilibrium eventually strongly monotone skew-product semiflow

A high level of extra-pair paternity in the Chestnut Thrush(Turdus rubrocanus)

在线全文

学校读者我要写书评

暂无评论

Avian Research 2023年第4期14卷 679-684页

作者： huan Liu Yun fang Yingqiang Lou Yuehua Sun Key Laboratory of Animal Ecology and Conservation Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China

Extra-pair copulation(EPC)can potentially maximize individual reproductive fitness,and this process may involve sexual selection of male and female traits that reflect individual *** studies have implied that adult characteristics are associated with the probability of extra-pair paternity(EPP),but it differs between ***,there are relatively few examples of the adaptive rationale for females’engagement in EPCs based on an examination of these more traditionally recorded traits,in combination with female flight-mediated traits such as wing *** investigated whether EPP existed in the wild Chestnut Thrush(Turdus rubrocanus)population during three breeding seasons(2019–2021),and whether paternity was related to morphological traits of males and *** highly variable microsatellite loci were used to identify paternity,and generalized linear mixed models were used to analyze the relationship between paternity and morphological *** found that EPP existed in the Chestnut Thrush.53.3%(N=41/77)of the broods contained at least one extra-pair offspring(EPO),and 34.6%(N=72/208)of the nestlings were *** also found that male wing length was negatively associated with the probability of EPP and the proportion of *** body length was positively related to the probability of *** female body condition and mass were negatively associated with the proportion of *** other traits of male and female did not relate to the probability of EPP or the proportion of ***-pair males had better body condition compared to the males they *** did not differ from their half-siblings in terms of body size or body *** results suggest that body size and body condition were associated with EPP in the Chestnut *** study provides fundamental information for further studies on the evolution and maintenance of EPP in the Chestnut Thrush,and it is also useful for the comparison of EPP among Turdus species.

关键词： Chestnut Thrush Extra-pair paternity Microsatellite Morphological traits

mRNA therapeutics:New vaccination and beyond

在线全文

学校读者我要写书评

暂无评论

Fundamental Research 2023年第5期3卷 749-759页

作者： huan-huan Wei Liangliang zheng Zefeng Wang Bio-med Big Data Center CAS Key Laboratory of Computational BiologyCAS Shanghai Institute of Nutrition and HealthShanghai 200032China University of Chinese Academy of Sciences Chinese Academy of Sciences(CAS)Beijing 100049China CirCode BioMedicine PudongShanghai 200131China

The idea of mRNA therapy had been conceived for decades before it came into reality during the Covid-19 *** mRNA vaccine emerges as a powerful and general tool against new viral infections,largely due to its versatility and rapid *** addition to prophylactic vaccines,mRNA technology also offers great promise for new applications as a versatile drug ***,realizing the conceptual potential faces considerable challenges,such as minimal immune stimulation,high and long-term expression,and efficient delivery to target cells and *** we review the applications of mRNA-based therapeutics,with emphasis on the innovative design and future challenges/*** addition,we also discuss the next generation of mRNA therapy,including circular mRNA and self-amplifying *** aim to provide a conceptual overview and outlook on mRNA therapeutics beyond prophylactic vaccines.

关键词： mRNA therapeutics mRNA medicine mRNA vaccine Protein-replacement therapy Circular RNA RNA delivery

Simulating Eastern-and Central-Pacific Type ENSO Using a Simple Coupled Model

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Atmospheric Sciences 2018年第6期35卷 671-681页

作者： Xianghui fang Fei zheng Institute of Atmospheric Sciences Fudan University International Center for Climate and Environment Science (ICCES) Institute of Atmospheric PhysicsChinese Academy of Sciences Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science and Technology

Severe biases exist in state-of-the-art general circulation models（GCMs） in capturing realistic central-Pacific（CP） El Nino structures. At the same time, many observational analyses have emphasized that thermocline（TH） feedback and zonal advective（ZA） feedback play dominant roles in the development of eastern-Pacific（EP） and CP El Nino-Southern Oscillation（ENSO）, respectively. In this work, a simple linear air-sea coupled model, which can accurately depict the strength distribution of the TH and ZA feedbacks in the equatorial Pacific, is used to investigate these two types of El Nino. The results indicate that the model can reproduce the main characteristics of CP ENSO if the TH feedback is switched off and the ZA feedback is retained as the only positive feedback, confirming the dominant role played by ZA feedback in the development of CP ENSO. Further experiments indicate that, through a simple nonlinear control approach, many ENSO characteristics,including the existence of both CP and EP El Nino and the asymmetries between El Nino and La Nina, can be successfully captured using the simple linear air-sea coupled model. These analyses indicate that an accurate depiction of the climatological sea surface temperature distribution and the related ZA feedback, which are the subject of severe biases in GCMs, is very important in simulating a realistic CP El Nino.

关键词： central-Pacific El Nino eastern-Pacific El Nino simple coupled model simulation asymmetry

STOCHASTIC PROCESS OF SEDIMENT IN SEDIMENTATION BASIN

在线全文

学校读者我要写书评

暂无评论

Journal of Hydrodynamics 1992年第4期4卷 66-71页

作者： zheng, Bongmin fang, Hongwei Wuhan Univ of Hydraulic and Electric Engineering Wuhan China

Suspended movement is supported by eddy of river. In this paper the turbulent stochastic regularity of flow and sediment was adopted and the settling model of the suspended movement was established. Then, stochastic regularity of the sediment in sedimentation basin was investigated. The calculating results were compared with measured data. The results are in good agreement and the calculating method is very simple. The divided diameter of washload and bed material load was discussed from the relation of turbulent intensity and sediment settling velocity.

关键词： Flow of water Sediment transport Sedimentation Turbulence