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Nano-Micro Letters 2025年第2期17卷 376-386页

作者： Wei-Min Qin Zhongliang Li Wen‑Xia Su jia‑Min Hu Hanqin Zou Zhixuan Wu Zhiqin Ruan Yue‑Peng cai Kang Li Qifeng zheng School of Chemistry South China Normal UniversityGuangzhou 510006People’s Republic of China Key Laboratory of Functional Metal‑Organic Compounds of Hunan Province College of Chemistry and Material ScienceHengyang Normal UniversityHengyang 421008People’s Republic of China Guangzhou Key Laboratory of Energy Conversion and Energy Storage Materials Guangzhou 510006People’s Republic of China

Porous organic cages(POCs)with permanent porosity and excellent host–guest property hold great potentials in regulating ion transport behavior,yet their feasibility as solid-state electrolytes has never been testified in a practical ***,we design and fabricate a quasi-solid-state electrolyte(QSSE)based on a POC to enable the stable operation of Li-metal batteries(LMBs).Benefiting from the ordered channels and cavity-induced anion-trapping effect of POC,the resulting POC-based QSSE exhibits a high Li+transference number of 0.67 and a high ionic conductivity of 1.25×10^(−4) S cm^(−1) with a low activation energy of 0.17 *** allow for homogeneous Li deposition and highly reversible Li plating/stripping for over 2000 *** a proof of concept,the LMB assembled with POC-based QSSE demonstrates extremely stable cycling performance with 85%capacity retention after 1000 ***,our work demonstrates the practical applicability of POC as SSEs for LMBs and could be extended to other energy-storage systems,such as Na and K batteries.

关键词： Porous organic cage Cavity-induced anion-trapping Quasi-solid-state electrolyte Homogeneous Li+flux Lithium metal battery

Synergistic promotion strategy of “dual-site” and “dual-path” to enhance the C–C coupling between CO2 and HCHO driven by photoelectrocatalysis

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Journal of Energy Chemistry 2025年第1期100卷 39-49页

作者： Hongqiang Yang jianfeng zheng Guoyu Wang Yifei Gao Yatao Yang jia Li Xiaojin Han Yan Cui Zhanggen Huang National Key Laboratory of High Efficiency and Low Carbon Utilization of Coal Institute of Coal Chemistry Chinese Academy of Science University of Chinese Academy of Science Shenyang University of Chemical Technology

Photoelectrocatalytic coupling CO2and volatile organic compounds （VOCs） is a promising green strategy for the synergistic conversion of the two carbon-containing resources to *** catalytic efficiency is always at the mercy of chemical inertness of CO2and the competitive hydrogen evolution of ***,a modified g-C3N4/ZnAl-LDH Z-scheme heterojunction catalyst with dual reaction site was rationally designed and precisely *** Faraday efficiency of ethanol reached 68.67%with a corresponding formation rate of 227.3μmol *** revealed by in-situ characterizations and density functional theory calculations,CO2and HCHO were absorbed at Zn site and N site,***,*CO generated from CO2and HCHO was converted to*CH3O and*CHO on the dual-active-site *** detailed reaction mechanism experiments indicated that C–C coupling only occurred between*CO and*CH3O in electrocatalysis *** from the“*CO+*CH3O”path,another“*CO+*CHO”coupling path was also detected in photoelectrocatalytic *** selectivity of ethanol was significantly enhanced due to the synthesis of dual-site catalyst and the dual-path coupling path between CO2and HCHO simultaneously driven by light and electricity.

关键词： Photoelectrocatalysis Z-scheme C–C coupling Ethanol

Passive activity enhances residual control ability in patients with complete spinal cord injury

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Neural Regeneration Research 2025年第8期20卷 2337-2347页

作者： Yanqing Xiao Mingming Gao Zejia He jia zheng Hongming Bai jia-Sheng Rao Guiyun Song Wei Song Xiaoguang Li Beijing Key Laboratory for Biomaterials and Neural Regeneration Beijing Advanced Innovation Center for Biomedical EngineeringSchool of Biological Science and Medical EngineeringBeihang UniversityBeijingChina Department of Rehabilitation Evaluation China Rehabilitation Research CenterBeijingChina Cardiac Center Beijing Children’s HospitalCapital Medical UniversityBeijingChina The State Key Laboratory of Virtual Reality Technology and Systems Beihang UniversityBeijingChina Department of Rehabilitation Engineering China Rehabilitation Science InstituteBeijingChina

Patients with complete spinal cord injury retain the potential for volitional muscle activity in muscles located below the spinal injury ***,because of prolonged inactivity,initial attempts to activate these muscles may not effectively engage any of the remaining neurons in the descending pathway.A previous study unexpectedly found that a brief clinical round of passive activity significantly increased volitional muscle activation,as measured by surface *** this study,we further explored the effect of passive activity on surface electromyographic signals during volitional control tasks among individuals with complete spinal cord *** patients with chronic complete thoracic spinal cord injury were *** electromyography data from eight major leg muscles were acquired and compared before and after the passive activity *** results indicated that the passive activity led to an increased number of activated volitional muscles and an increased frequency of *** the cumulative root mean square of surface electromyography amplitude for volitional control of movement showed a slight increase after passive activity,the difference was not statistically *** findings suggest that brief passive activity may enhance the ability to initiate volitional muscle activity during surface electromyography tasks and underscore the potential of passive activity for improving residual motor control among patients with motor complete spinal cord injury.

关键词： complete spinal cord injury cycle training epidural electrical stimulation motor training passive activity physiological state spinal cord circuit surface electromyography volitional control task

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泄流的压力脉动及其概化设计

水动力学研究与进展（A辑） 1997年第1期12卷 102-112页

作者：孙小鹏薛盘珍吕家才河海大学水科所南京210098

泄流脉动压力的谱密度可以分为四种基本类型,每种类型都与水流的内部流动结构和流态有关,并存在着大致的对应关系。同类泄水建筑物在类似泄水条件下的压力脉动特性存在统计规律性。本文根据大量原型观测资料归纳分析了十种常见泄流条件... 详细信息

泄流脉动压力的谱密度可以分为四种基本类型,每种类型都与水流的内部流动结构和流态有关,并存在着大致的对应关系。同类泄水建筑物在类似泄水条件下的压力脉动特性存在统计规律性。本文根据大量原型观测资料归纳分析了十种常见泄流条件下的水流脉动压力特性,并为有效地分析研究压力脉动的各种效应,提出了压力脉动概化设计的新思想和具体方法。

关键词：泄流脉动压力概化设计水工建筑压力脉动

RDX级配对醇醛高聚物粘结炸药触变性的影响

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含能材料 2016年第12期24卷 1198-1204页

作者：刘慧慧郑申声蔡贾林蒋全萍罗观李尚斌中国工程物理研究院化工材料研究所四川绵阳621999

为了研究浇注型醇醛高聚物粘结炸药的触变性能,采用触变环法探索了黑索今(RDX)级配及颗粒含量对料浆触变性的影响。触变环面积用于表征料浆的触变程度。结果表明,该料浆体系是假塑性流体,不同RDX级配的料浆具有不同程度的触变性。RDX级... 详细信息

为了研究浇注型醇醛高聚物粘结炸药的触变性能,采用触变环法探索了黑索今(RDX)级配及颗粒含量对料浆触变性的影响。触变环面积用于表征料浆的触变程度。结果表明,该料浆体系是假塑性流体,不同RDX级配的料浆具有不同程度的触变性。RDX级配数越高、颗粒越大的料浆触变性越小。小颗粒含量越高,大颗粒和中颗粒的级配对降低料浆触变性的影响越大。料浆的触变程度与小颗粒RDX含量呈正相关关系,与大颗粒RDX含量呈负相关关系。

关键词：高聚物粘结炸药(PBX) 颗粒大小粒度级配触变性滞回环

G Protein-Coupled Estrogen Receptor 1 Negatively Regulates the Proliferation of Mouse-Derived Neural Stem/Progenitor Cells via Extracellular Signal-regulated Kinase Pathway

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G Protein-Coupled Estrogen Receptor 1 Negatively Regulates t...

Sine oculis homeobox homolog family function in gastrointestinal cancer:Progression and comprehensive analysis

第十四届中国医师协会神经外科医师年会

作者： Jun Zhong Hong-fei Ge Chao Zhang Jing-yu Chen Huan-huan Li Xuan-yu Fang Liang Tan Xin Liu zheng-cai jia Hua Feng Rong Hu Department of Neurosurgery and Key Laboratory of Neurotrauma Southwest HospitalThird Military Medical University （Army Medical university）

G protein-coupled estrogen receptor 1（GPER1, also known as GPR30） has been reported to play a wide range of function in the central nervous system（CNS）. However, whether GPER1 is expressed by neural stem/progenitor cells（NSPCs） and its role has not been established. Here, we found the expression of GPER1 in mouse-derived NSPCs via western blot and immunofluorescent staining. Moreover, we revealed that specific activation of GPER1 by the agonist G1 decreased the proliferation of NSPCs in a dose-dependent manner. The neurosphere formation assay and Ki67 staining further demonstrated that activation of GPER1 inhibited the proliferation of NSPCs. Additionally, the inhibitory effect of G1 on the proliferation of NSPCs could be blocked by the specific GPER1 antagonist G15. Intriguingly, ERK pathway was involved in the negative effect of GPER1 on the proliferation of NSPCs, because the phosphorylation level of ERK in NSPCs was remarkably decreased during G1 treatment. However, the antagonist G15 reversed the down-regulated level of p-ERK. Knock-down GPER1 also reversed the inhibitory effect of G1 on NSPCs proliferation. Together, our results provide the first evidence that GPER1 is expressed by NSPCs and its activation negatively modulates the proliferation of NSPCs, highlighting the importance of GPER1 in regulating NSPC behaviors.

关键词： Neural stem/progenitor cells G protein-coupled estrogen receptor 1 Proliferation Extracellular signal-regulated kinase

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World Journal of Clinical Oncology 2025年第1期16卷 10-24页

作者： Yang-zheng Lan zheng Wu Wen-jia Chen Xin-Ning Yu Hua-Tao Wu Jing Liu Department of The Breast Center Cancer Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina Department of General Surgery First Affiliated Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina

The sine oculis homeobox homolog(SIX)family,a group of transcription factors characterized by a conserved DNA-binding homology domain,plays a critical role in orchestrating embryonic development and organogenesis across various organisms,including *** six distinct members,from SIX1 to SIX6,each member contributes uniquely to the development and differentiation of diverse tissues and organs,underscoring the versatility of the SIX *** or mutations in SIX genes have been implicated in a spectrum of developmental disorders,as well as in tumor initiation and progression,highlighting their pivotal role in maintaining normal developmental trajectories and cellular *** to target the transcriptional complex of the SIX gene family have emerged as a promising strategy to inhibit tumor *** the development of inhibitors targeting this gene family is still in its early stages,the significant potential of such interventions holds promise for future therapeutic ***,this review aimed to comprehensively explore the advancements in understanding the SIX family within gastrointestinal cancers,focusing on its critical role in normal organ development and its implications in gastrointestinal cancers,including gastric,pancreatic,colorectal cancer,and hepatocellular *** conclusion,this review deepened the understanding of the functional roles of the SIX family and explored the potential of utilizing this gene family for the diagnosis,prognosis,and treatment of gastrointestinal cancers.

关键词： Sine oculis homeobox homolog Gastrointestinal cancer Transcription factor Development Regulation Diagnosis Therapeutics

Primary parenchymal squamous cell carcinoma of the kidney:A case report

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World Journal of Clinical Cases 2025年第4期13卷 34-40页

作者： Zhi-Hui zheng Bo Shao Chao-Min Xu Ke Wang jia-Zhu Wen Li-Kang Luo jia-Cheng Guan Department of Ultrasound The Second People’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina Department of Radiology Shulan(Quzhou)HospitalQuzhou 324000Zhejiang ProvinceChina Department of Radiology The Second People’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina Department of Pathology The Second people’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina

BACKGROUND Primary squamous cell carcinoma(SCC)of the renal parenchyma is extremely rare,with only nine cases *** SUMMARY This study reports a 51-year-old man with primary SCC of the renal *** patient was admitted with recurrent dull pain and discomfort in the right lumbar region,which had worsened over 2 weeks,accompanied by painful gross *** antigen(SCCA)levels were elevated,and imaging revealed a renal mass with associated *** patient underwent laparoscopic unilateral nephrectomy and lymph node *** pathology confirmed highly differentiated SCC with necrosis in the right renal parenchyma,with negative renal pelvis and *** pathological stage was *** months after surgery,the tumor recurred with involvement of the liver,right psoas major muscle,and inferior vena *** patient refused chemotherapy and succumbed to the disease 6 months postoperatively due to disease *** We report a case of primary SCC of the renal parenchyma,a rare renal *** clinical symptoms,laboratory tests,and imaging findings are nonspecific,making accurate and timely diagnosis *** to the literature,for patients with renal calculi accompanied by a renal mass,elevated serum SCCA levels,and magnetic resonance imaging showing cystic or cystic-solid masses within the kidney with pseudocapsules and heterogeneous mild enhancement,the possibility of this disease should be considered.

关键词： Renal tumor Renal parenchyma Squamous cell carcinoma Renal calculi Computed tomography Case report

Visualization of the protective role of estrogen against female liver fibrosis via an ER viscosity NIR fluorescent probe

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Science China Chemistry 2025年第1期 360-368页

作者： zheng Liu Changyu Zhang Zipeng Li Wanying Ma jia Liu Xiang Xia Ning Xu Wen Sun jianjun Du jiangli Fan Xiaojun Peng State Key Laboratory of Fine Chemicals Dalian University of Technology Ningbo Institute of Dalian University of Technology

Endoplasmic reticulum(ER) viscosity has emerged as a new potential biomarker for hepatic fibrosis(HF). Herein, we report the first ER-targeting viscosity-responsive near-infrared(NIR) fluorescent probe HBT-PP for investigations of HF *** twisted intramolecular charge transfer(TICT) and the excited state intramolecular proton transfer(ESIPT) are combined to endow HBT-PP with the selective response towards viscosity(～62-fold) and a super large stokes shift(～320 nm). HBT-PP mainly targets organelle ER and is able to image the drug-or alcohol-induced viscosity elevation in living cells. Significantly,HBT-PP was successfully applied to visualize the gender difference in HF and the protective role of estrogen in restraining HF progression. Of note, after 10 min of stain with HBT-PP, HF lesions showed a stage-based response, indicating the potential of this probe in fast and early diagnosis of HF. These results clearly demonstrated the promising application of HBT-PP as a new tool for exploring ER viscosity-involved physiological and pathological processes.

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不同水平击剑运动员弓步动作中膝关节的生物力学分析

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中国体育科技 2015年第4期51卷 58-62页

作者：管延飞郭黎吴娜娜郑加财刘海瑞上海体育学院上海200438

目的:分析不同水平击剑运动员在弓步动作过程中双侧膝关节生物力学表现的差异,探讨影响弓步速度的生物力学因素。方法:7名优秀击剑运动员和9名一般水平击剑运动员以最快速度完成原地向前的大幅度弓步动作,同步采集、分析运动员弓步速度... 详细信息

目的:分析不同水平击剑运动员在弓步动作过程中双侧膝关节生物力学表现的差异,探讨影响弓步速度的生物力学因素。方法:7名优秀击剑运动员和9名一般水平击剑运动员以最快速度完成原地向前的大幅度弓步动作,同步采集、分析运动员弓步速度、后腿蹬地地面反作用力及弓步过程中双侧膝关节的生物力学表现。结果:优秀运动员弓步动作中水平方向重心速度峰值、后腿蹬地地面水平方向反作用力峰值以及后腿伸膝力矩峰值均显著高于一般运动员(P<0.05),后腿伸膝功率峰值到达时间显著小于一般运动员(P<0.05);弓步启动后所有运动员前腿膝关节先屈后伸,优秀运动员前腿屈膝程度、伸膝角速度峰值均显著低于一般运动员(P<0.05),前腿伸膝时间显著大于一般运动员(P<0.05)。结论:后腿膝关节在弓步过程中的动力学表现是决定击剑运动员弓步速度的主要因素;不同水平击剑运动员弓步动作中后腿蹬地能力的差异导致了前腿膝关节运动学表现的差异;弓步启动时,前腿伸膝之前屈膝程度过大可能会限制弓步距离,同时对弓步落地和出剑选择产生不利影响。

关键词：击剑弓步膝关节爆发力重心速度