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Numerical Mathematics(Theory,Methods and Applications) 2024年第1期17卷 145-180页

作者： Yizhong Sun Jiangshan wang Haibiao zheng School of Mathematical Sciences East China Normal UniversityShanghaiChina School of Mathematical Sciences Ministry of Education Key Laboratory of Mathematics and Engineering ApplicationsShanghai Key Laboratory of PMMPEast China Normal UniversityShanghaiChina

The simulation of multi-domain,multi-physics mathematical models with uncertain parameters can be quite demanding in terms of algorithm design and com-putation *** main objective in this paper is to examine a physical interface coupling between two random dissipative systems with uncertain *** to the complexity and uncertainty inherent in such interface-coupled problems,un-certain diffusion coefﬁcients or friction parameters often arise,leading to consid-ering random *** employ Monte Carlo methods to produce independent and identically distributed deterministic heat-heat model samples to address ran-dom systems,and adroitly integrate the ensemble idea to facilitate the fast calcu-lation of these *** achieve unconditional stability,we introduce the scalar auxiliary variable(SAV)method to overcome the time constraints of the ensemble implicit-explicit ***,for a more accurate and stable scheme,the ensemble data-passing algorithm is raised,which is unconditionally stable and convergent without any auxiliary *** algorithms employ the same co-efﬁcient matrix for multiple linear systems and enable easy parallelization,which can signiﬁcantly reduce the computational ***,numerical experiments are conducted to support the theoretical results and showcase the unique features of the proposed algorithms.

关键词： Scalar auxiliary variable,ensemble algorithm,random interface-coupled problems,implicit-explicit partitioned method,data-passing partitioned method

Aspartoacylase suppresses prostate cancer progression by blocking LYN activation

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Military Medical Research 2024年第2期11卷 180-205页

作者： Hong Weng kang-Ping Xiong wang wang Kai-Yu Qian Shuai Yuan Gang wang Fang Yu Jun Luo Meng‑Xin Lu Zhong‑Hua Yang Tao Liu Xing Huang Hang zheng Xing-Huan wang Department of Urology Zhongnan Hospital of Wuhan UniversityWuhan 430071China Center for Evidence‑Based and Translational Medicine Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Biological Repositories Zhongnan Hospital of Wuhan UniversityWuhan 430071China Hubei Key Laboratory of Tumor Biological Behaviors Wuhan 430071China Department of Pathology Zhongnan Hospital of Wuhan UniversityWuhan 430071China Center for Pathology and Molecular Diagnostics Wuhan UniversityWuhan 430071China Wuhan Research Center for Infectious Diseases and Cancer Chinese Academy of Medical SciencesWuhan 430071China

Background:Globally,despite prostate cancer(PCa)representing second most prevalent malignancy in male,the precise molecular mechanisms implicated in its pathogenesis remain ***,elucidating the key molecular regulators that govern disease progression could substantially contribute to the establishment of novel therapeutic strategies,ultimately advancing the management of ***:A total of 49 PCa tissues and 43 adjacent normal tissues were collected from January 2017 to December 2021 at Zhongnan Hospital of Wuhan *** advanced transcriptomic methodologies were employed to identify differentially expressed mRNAs in *** expression of aspartoacylase(ASPA)in PCa was thoroughly evaluated using quantitative real-time PCR and Western blotting *** elucidate the inhibitory role of ASPA in PCa cell proliferation and metastasis,a comprehensive set of in vitro and in vivo assays were conducted,including orthotopic and tumor-bearing mouse models(n=8 for each group).A combination of experimental approaches,such as Western blotting,luciferase assays,immunoprecipitation assays,mass spectrometry,glutathione S-transferase pulldown experiments,and rescue studies,were employed to investigate the underlying molecular mechanisms of ASPA's action in *** Student‘s t-test was employed to assess the statistical significance between two distinct groups,while one-way analysis of variance was utilized for comparisons involving more than two groups.A two-sided P<0.05 was deemed to indicate statistical ***:ASPA was identified as a novel inhibitor of PCa *** expression of ASPA was found to be significantly down-regulated in PCa tissue samples,and its decreased expression was independently associated with patients’prognosis(HR=0.60,95%CI 0.40–0.92,P=0.018).Our experiments demonstrated that modulation of ASPA activity,either through gain-or loss-of-function,led to the suppression or enhancement of PCa cell proliferation,mig

关键词： Prostate cancer Aspartoacylase LYN JNK AP-1 C-Jun Phosphorylation

Stall Evolution Mechanism of a Centrifugal Compressor with a Wide-Long Vaneless Diffuser

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Journal of Thermal Science 2024年第3期33卷 899-913页

作者： ZHANG Lei kang Jiacheng LANG Jinhua AN Guangyao ZHANG Qian wang Longyao wang Qifang Department of Power Engineering North China Electric Power UniversityBaoding071003China Hebei Key Laboratory of Low Carbon and High Efficiency Power Generation Technology North China Electric Power UniversityBaoding071003China

The rotating stall mechanism is of high importance for the stability of centrifugal compressors and thermal power *** majority of research concerning this topic has concentrated on the initial stall ***,the evolution of stall cells in wide-long diffusers has not been comprehensively *** this paper,the causes of rotating stall in the wide-long diffuser and the three-dimensional evolution mechanism of stall cells during the stall process were thoroughly *** the stall induction phase,an annulus vortex structure was found in the reverse-flow zone near the hub side of the diffuser outlet,which was the initial form of stall *** whole evolution process of stall cells was divided into three phases as the flow rate *** the initial stall phase,the dynamic equilibrium was built under effects of the impeller wake and the adverse pressure *** a result,the number of stall cells was kept at seven and the size of stall cells remained *** the transition phase,the flow in the diffuser became *** cells extended to the impeller outlet,and the effect of the wake flow was strengthened *** cells started integrating and separating *** a result,the number and propagation speed of stall cells varied periodically at a constant mass flow *** the deep stall phase,the size of stall cells remained unchanged,and the number of stall cells kept at *** study has important practical guidance and engineering value for the high-efficiency design and safe operation of centrifugal compressors.

关键词： centrifugal compressor wide-long vaneless diffuser stall evolution mechanism wake flow

Resilience-oriented Transmission Expansion Planning with Optimal Transmission Switching Under Typhoon Weather

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CSEE Journal of Power and Energy Systems 2024年第1期10卷 129-138页

作者： Yang Yuan Heng Zhang Haozhong Cheng zheng wang Key Laboratory of Control of Power Transmission and Conversion Ministry of EducationElectrical Engineering DepartmentShanghai Jiao Tong UniversityShanghaiChina State Grid East China Branch ShanghaiChina

This paper presents resilience-oriented transmission expansion planning(RTEP)with optimal transmission switching(OTS)model under typhoon *** proposed model carefully considers the uncertainty of component vulnerability by constructing a typhoon-related box uncertainty set where component failure rate varies within a range closely related with typhoon ***,a min-max-min model is developed to enhance transmission network resilience,where the upper level minimizes transmission lines investment,the middle level searches for the probability distribution of failure status leading to max worst-case expected load-shedding(WCEL)under typhoon,and the lower level optimizes WCEL by economic dispatch(ED)and OTS.A nested decomposition algorithm based on benders decomposition is developed to solve the *** studies of modified IEEE 30-bus and 261-bus system of a Chinese region illustrate that:a)the proposed RTEP method can enhance resilience of transmission network with less investment than widely used RTEP method based on attacker and defender(DAD)model,b)the influence of OTS on RTEP is closely related with contingency severity and system scale and c)the RTEP model can be efficiently solved even in a large-scale system.

关键词： Decomposition algorithm optimal transmission switching resilience transmission expansion planning uncertainty vulnerability

Surfactant-metal-organic framework complexes and their derivatives:advances in electrocatalysis

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Science China Chemistry 2024年第10期67卷 3209-3222页

作者： Yining Liu Mengying wang Zuozhong Liang Haoquan zheng Key Laboratory of Applied Surface and Colloid Chemistry Ministry of EducationSchool of Chemistry and Chemical EngineeringShaanxi Normal UniversityXi’an 710119China

Metal-organic frameworks(MOFs)and their derivatives received more and more attention due to the diverse morphologies,rich porous structures,and tunable metal active sites,which have been widely used in energy-related electrocatalytic ***,a class of compounds with hydrophilic and hydrophobic portions in the molecular structure,are able to modulate the properties of liquid and solid *** play a crucial role in controlling the shape and size of MOFs,which helps optimize electrocatalytic performance,especially in improving the exposure and accessibility of catalytic active *** this review,we first outline the types and applications of ***,we describe the interface modulation and reaction mechanism of different surfactants during the forming of MOFs and their ***,we discuss the current applications of surfactant-modified MOFs and their derivatives in *** review provides a better understanding of surfactantassistant structure regulation and electrocatalytic activity study of MOFs and their derivatives.

关键词： metal-organic frameworks surfactants interface modulation electrocatalysis

Foundation models meet visualizations: Challenges and opportunities

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Computational Visual Media 2024年第3期10卷 399-424页

作者： Weikai Yang Mengchen Liu zheng wang Shixia Liu School of Software Tsinghua UniversityBeijing 100084China Microsoft Redmond 98052USA

Recent studies have indicated that foundation models, such as BERT and GPT, excel atadapting to various downstream tasks. This adaptability has made them a dominant force in buildingartificial intelligence (AI) systems. Moreover, a newresearch paradigm has emerged as visualizationtechniques are incorporated into these models. Thisstudy divides these intersections into two researchareas: visualization for foundation model (VIS4FM)and foundation model for visualization (FM4VIS).In terms of VIS4FM, we explore the primary roleof visualizations in understanding, refining, and evaluating these intricate foundation models. VIS4FMaddresses the pressing need for transparency, explainability, fairness, and robustness. Conversely, in termsof FM4VIS, we highlight how foundation models canbe used to advance the visualization field itself. Theintersection of foundation models with visualizations ispromising but also introduces a set of challenges. Byhighlighting these challenges and promising opportunities, this study aims to provide a starting point forthe continued exploration of this research avenue.

关键词： visualization artificial intelligence(AI) machine learning foundation models visualization for foundation model(VIS4FM) foundation model for visualization(FM4VIS)

The influence of inter-band rock on rib spalling in longwall panel with large mining height

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International Journal of Mining Science and Technology 2024年第4期34卷 427-442页

作者： Jiachen wang Meng Li Zhaohui wang zheng Li Han Zhang Shixiong Song School of Energy and Mining Engineering China University of Mining and Technology-BeijingBeijing 100083China Coal Industry Engineering Research Center of Top-coal Caving Mining Beijing 100083China Faculty of Engineering Hokkaido UniversitySapporo 060-8628Japan

In order to improve rib stability,failure criteria and instability mode of a thick coal seam with inter-band rock layer are analysed in this study.A three-dimensional mechanical model is established for the rib by considering the rock layer.A safety factor is defined foy the rib,and it is observed that the safety factor exhibits a positive correlation with the thickness and strength of the inter-band rock.A calculation method for determining critical parameters of the rock layer is presented to ensure the rib *** is revealed that incomplete propagation of the fracture at the hard rock constitutes a fundamental prerequisite for ensuring the rib *** influence of the position of the inter-band rock in the coal seam on failure mechanism of the rib was thoroughly investigated by developing a series of physical models for the rib at the face *** best position for the inter-band rock in the coal seam is at a height of 1.5 m away from the roof line,which tends to provide a good stability state for the *** different inter-band rock positions,two ways of controlling rib by increasing supports stiffness and flexible grouting reinforcement are proposed.

关键词： Rib spalling Inter-band rock Large mining height Limit analysis Physical model experiment Numerical simulation

Modeling of Rectangular Microchannel Heat Sink with Non-Uniform Channels and Multi-Objective Optimization

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Journal of Thermal Science 2024年第5期33卷 1701-1711页

作者： SHANG Xueshuo wang Yixin LI Qingwen wang Rui CUI zheng SHAO Wei Institute of Advanced Technology Shandong UniversityJi'nan 250014China Institute of Thermal Science and Technology Shandong UniversityJi'nan 250014China Shandong Institute of Advanced Technology Ji'nan 250100China

Rectangular microchannel heat sinks(MCHS)are widely used to cool high-heat-flux electronic ***,previous studies focused mainly on MCHS with uniform channels(UCs).This study considers a microchannel heat sink with non-uniform channels(NUCs).A mathematical model is developed based on energy equations and the Darcy flow *** expressions for total thermal resistance and coolant pressure drop are derived using the thermoelectric *** and numerical simulations are performed to verify the mathematical *** non-uniformity increases,total coolant pressure drop decreases but at the cost of higher thermal *** overall performance of NUCs is better than that of UCs because of their lower ratio of pumping power to cooling *** transfer performance of NUCs changes little for more than 120 channels and depends mainly on channel arrangement.A multi-objective optimization is conducted to minimize the thermal resistance and pumping power of an *** optimal NUC saves 64%pumping power compared with a conventional UC for the total thermal resistance of 0.1℃/W,indicating that the use of non-uniform channels could be very helpful to reduce the flow resistance of MCHS.

关键词： microchannel heat sink non-uniform channel mathematical model multi-objective optimization

Semiconductor fibers for textile integrated electronic systems

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National Science Review 2024年第6期11卷 100-101页

作者： Yuanyuan zheng Zhen wang Peining Chen Huisheng Peng State Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular ScienceInstitute of Fiber Materials and Devices and Laboratory of Advanced Materials Fudan University

Over 5000 years of development, the functions of clothing have been mainly limited in warmth and modesty. With the development of smart fibers, fabrics are anticipated to revolutionize multidisciplinary applications, ... 详细信息

关键词： Fibers

Steady-state Voltage Security-constrained Optimal Frequency Control for Weak HVDC Sending-end AC Power Systems

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Journal of Modern Power Systems and Clean Energy 2024年第2期12卷 658-669页

作者： Qiangqiang wang Liangzhong Yao Jian Xu Yuping zheng Wei Li Wei wang School of Electrical Engineering and Automation Wuhan UniversityWuhan 430072China Hubei Engineering and Technology Research Center for AC/DC Intelligent Distribution Network(Wuhan University) Wuhan 430072China State Key Laboratory of Smart Grid Protection and Control NARI Group Corporation(State Grid Electric Power Research Institute)Nanjing 211106China

Due to the fact that a high share of renewable energy sources(RESs)are connected to high-voltage direct current(HVDC)sending-end AC power systems,the voltage and frequency regulation capabilities of HVDC sending-end AC power systems have *** has resulted in potential system operating problems such as overvoltage and overfrequency,which occur simultaneously when block faults exist in the HVDC *** this study,a steady-state voltage security-constrained optimal frequency control method for weak HVDC sending-end AC power systems is *** integrated virtual inertia control of RESs is employed for system frequency *** dynamic reactive power compensation devices are utilized to control the voltage of all nodes meet voltage security ***,an optimization model that simultaneously considers the frequency and steady-state voltage security constraints for weak HVDC sending-end AC power systems is *** optimal control scheme with the minimum total cost of generation tripping and additional dynamic reactive power compensation required is obtained through the optimization *** are conducted on a modified IEEE 9-bus test system and practical Qing-Yu line commutated converter based HVDC(LCC-HVDC)sending-end AC power system to verify the effectiveness of the proposed method.

关键词： Renewable energy source(RES) high-voltage direct current(HVDC) AC power system optimal frequency control steady-state voltage security dynamic reactive power compensation