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Irpexoates A-D,Four Triterpenoids with Malonyl Modifications from the Fruiting Bodies of the Medicinal Fungus Irpex lacteus

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Natural Products and Bioprospecting 2018年第3期8卷 171-176页

作者： Yang Tang Zhen-Zhu Zhao zheng-hui li Tao Feng He-Ping Chen Ji-Kai liu State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of BotanyChinese Academy of SciencesKunming 650201People’s Republic of China School of Pharmaceutical Sciences South-Central University for NationalitiesWuhan 430074People’s Republic of China University of Chinese Academy of Sciences Beijing 100049People’s Republic of China

Four eburicane-type triterpenoids with malonyl modifications,namely irpexoates A-D(1-4),were isolated from the fruiting bodies of the medicinal fungus Irpex *** structures of the new compounds were established by extensive spectroscopic methods,including 1D and 2D NMR,HRESIMS spectroscopic *** B(2)displayed weak cytotoxicity against four human cancer cell lines(A-549,SMMC-7721,MCF-7,SW480)with IC50 values varying from 22.9 to 34.0 pM,and irpexoate D(4)showed weak cytotoxicity against the human cancer cell line SW480 with an IC50 value of 35.2μM.

关键词： Irpex lacteus Meruliaceae Eburicane Malonyl Cytotoxicity

Three New Triterpenoids from European Mushroom Tricholoma terreum

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Natural Products and Bioprospecting 2015年第4期5卷 205-208页

作者： Tao Feng Juan He Hong-lian Ai Rong Huang zheng-hui li Ji-Kai liu College of Pharmacy South-Central University for NationalitiesWuhan 430074China College of life Sciences South-Central University for NationalitiesWuhan 430074China

Three rare triterpenoids,saponaceolides Q–S(1–3),have been isolated from fruiting bodies of the mushroom Tricholoma *** structures were characterized based on extensive spectroscopic *** 1 showed certain cytotoxicit... 详细信息

关键词： Tricholoma terreum Triterpenoids Cytotoxicity

The Design and Implementation of the Syntax-Directed Editor Generator(SEG)

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Journal of Computer Science and Technology 1986年第4期1卷 39-48页

作者：郑国梁李辉 Nanjing University

SEG is a syntax-directed editor generator consisting of three parts:Meta,a meta languagewhich describes BNF-like syntax;a parser,which parses the syntax descriptions written in Metaand generates their driver tables;a syntax-directed editor,which performs editing operationsusing a *** to its ancestors(***,Gandalf),SEG is characterized by the followingfeatures:i)it is for a variety of languages so that the editor of a specific language can be easilyproduced;ii)multifile can be edited in multiwindow;iii)private environments can be set up byusers;iv)the PC-mouse with the dedicated menus enables users to enter commands correctlyand quickly;v)pretty-printing of program documents is done automatically or *** syntax-directed editors,any program edited by SEG is syntactically *** paperoutlines the SEG system and discusses the design principles and implementation techniques ofthe system.

关键词： SEG Meta Design

Correlation between grain size,mechanical properties and deformed microstructure of Fe-20Mn-6Al-0.6C-0.15Si low-density steel

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Journal of Iron and Steel Research International 2025年第1期32卷 282-292页

作者： Qi Zhang Guang-hui Chen zheng-liang Xue zheng-kun Chen Guang Xu State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan430081HubeiChina Key Laboratory for Ferrous Metallurgy and Resources Utilization of Ministry of Education Wuhan University of Science and TechnologyWuhan430081HubeiChina Red Eagle Novel Refractory Materials Research Institute Zhejiang Red Eagle Group Co.Ltd.Huzhou313000ZhejiangChina

The effects of austenite grain size on the deformed microstructure and mechanical properties of an Fe-20Mn-6Al-0.6C-0.15Si(wt.%)low-density steel were *** microstructure of the experimental steel after solution treatment was single austenitic *** austenite grain size increased with solution temperature and time.A model was established to show the relationship between temperature,time and austenite grain size for the experimental *** addition,as the solution temperature increased,the strength decreased,while the elongation first increased and then *** decrease in elongation after solution treatment at 1100℃ for 90 min is contributed to the over-coarse austenite ***,after solution treatment at 900℃ for 90 min,the strength-elongation product reached the highest value of 44.4 GPa%.As the austenite grain size increased,the intensity of//tensile direction fiber *** was accompanied by a decrease in dislocation density,resulting in a lower fraction of low-angle grain boundaries and a lower work hardening ***,the austenite grain size has a critical influence on the mechanical properties of the low-density *** grains lead to a lower yield strength due to the Hall-Petch effect and a lower tensile strength because of lower dislocation strengthening.

关键词： Austenitic low-density steel Solution treatment Grain size Mechanical property Deformed microstructure

New benzene derivatives from cultures of ascomycete Daldinia concentrica

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Natural Products and Bioprospecting 2013年第4期3卷 150-153页

作者： Tao FENG zheng-hui li Xia YIN Ze-Jun DONG Gang-Qiang WANG Xing-Yao li Yan li Ji-Kai liU State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China University of Chinese Academy of Sciences Beijing 100049China School of Chemistry and Chemical Engineering of Hunan University Changsha 410082China

Three new benzene derivatives,named daldins A-C(1-3),together with a known analogue,2-hydroxymethyl-3-(1-hydroxypropyl)phenol(4)have been isolated from cultures of ascomycete Daldinia *** structures of 1-4 with absolute configuration were established by means of spectroscopic methods and X-ray *** compounds showed no significant inhibition on five human cancer cell lines with IC50 values>40μmol.

关键词： Daldinia concentrica benzene derivatives absolute configuration

Unusual illudin-type sesquiterpenoids from cultures of Agrocybe salicacola

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Natural Products and Bioprospecting 2011年第2期1卷 87-92页

作者： liang-Yan liU ling ZHANG Tao FENG zheng-hui li Ze-Jun DONG Xing-Yao li Jia SU Yan li Ji-Kai liU State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China Graduate University of Chinese Academy of Sciences Beijing 100039China

Seven new illudin-type sesquiterpenoids,agrocybins A-G(1-7),along with three known analogues(8-10),have been isolated from the culture broth of the fungus Agrocybe *** structures were elucidated on the basis of extensive spectroscopic data analysis and comparison with data reported in the *** relative stereoconfigurations of 1 and 6 were elucidated by the X-ray crystallographic diffraction *** 1 was highly cyclized containing seven chiral carbons which arranged compactly in six rings.

关键词： Agrocybe salicacola sesquiterpenoid agrocybin stereoconfiguration X-ray

Two new drimane sesquiterpenoids from cultures of the basidiomycete Trichaptum biforme

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Natural Products and Bioprospecting 2013年第4期3卷 154-157页

作者： Xiao-Yan YANG Tao FENG Jian-Hai DING zheng-hui li Yan li Qiong-Ying FAN Ji-Kai liU State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China University of Chinese Academy of Sciences Beijing 100049China Hebei Normal University Hebei 050024China

Two new drimane sesquiterpenoids(1 and 2),as well as five known compounds(3-7),were isolated from the basidiomycete Trichaptum *** structures of new compounds were elucidated by extensive spectroscopic methods,and the known compounds were identified by comparing their spectroscopic data with those reported in the *** cytotoxicities results against five human cancer cell lines of compounds 1 and 2 were negligible.

关键词： Trichaptum biforme drimane sesquiterpenoids cytotoxicity

Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens

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Natural Products and Bioprospecting 2015年第1期5卷 23-28页

作者： Zhen-Zhu Zhao He-Ping Chen Tao Feng zheng-hui li Ze-Jun Dong Ji-Kai liu State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of BotanyChinese Academy of SciencesKunming 650201People’s Republic of China University of Chinese Academy of Sciences Beijing 100049People’s Republic of China

Four new sesquiterpenoids,namely 12-hydroxy-3-oxodrimenol(1),11-hydroxyacetoxydrim-7-en-3b-ol(2),2,6-dimethyl-7,10-epoxy-10-hydroxymethyldodeca-2,11-dien-6-ol(3),and 7,10-epoxy-2,6,10-trimethyldodeca-2,11-diene-4,6-diol(4),along with fourteen known compounds,were isolated from the cultures of Phellinidium *** structures of compounds 1–4 were established on the basis of extensive spectroscopic *** of them were evaluated for their cytotoxic activities.

关键词： Phellinidium sulphurascens Drimane 7,10-Epoxy-2,6,10-trimethyldodeca-2,11-diene

Vibralactone Biogenesis-Associated Analogues from Submerged Cultures of the Fungus Boreostereum vibrans

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Natural Products and Bioprospecting 2018年第1期8卷 37-45页

作者： He-Ping Chen Meng-Yuan Jiang Zhen-Zhu Zhao Tao Feng zheng-hui li Ji-Kai liu School of Pharmaceutical Sciences South-Central University for NationalitiesWuhan 430074People’s Republic of China Key Laboratory of Chemistry in Ethnic Medicinal Resources State Ethnic Affairs Commission&Ministry of EducationSchool of Ethnic MedicineYunnan Minzu UniversityKunming 650504People’s Republic of China

A scale-up fermentation of the fungus Boreostereum vibrans facilitated the isolation of six new vibralactone biogenesis-associated analogues,namely vibralactamide A(1),vibralactone T(2),13-O-lactyl vibralactone(3),10-O-acetyl vibralactone G(4),(11R,12R)-and(11S,12R)-vibradiol(5,6).Their structures were established via extensive spectroscopic analyses,specific optical rotation comparison,and Snatzke’s *** biosynthetic pathway for vibralactamide A was *** absolute configuration of vibralactone B was revised by single crystal X-ray diffraction *** work puts the divergent vibralactone biosynthesis pathway one step further and expands the structural diversity of vibralactone-associated compounds.

关键词： Basidiomycete Boreostereum vibrans Vibralactone Structure revision Snatzke’s method