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肚倍在各生长期的主要成分含量变化分析

生物资源 2017年第5期39卷 366-372页

作者：刘兰香査玉平陈京元郑华张雯雯徐涓张弘中国林业科学研究院资源昆虫研究所云南昆明650224 湖北省林科院湖北武汉430075

肚倍是一种商品化的五倍子,富含鞣质、没食子酸等重要成分,具有重要的药用价值及工业用途。研究不同生长发育时期五倍子主要成分的含量变化,探索变化规律对肚倍更深入的研究具有长远意义。本文以湖北省竹山县溢水镇东川苗圃、文峰乡肖... 详细信息

肚倍是一种商品化的五倍子,富含鞣质、没食子酸等重要成分,具有重要的药用价值及工业用途。研究不同生长发育时期五倍子主要成分的含量变化,探索变化规律对肚倍更深入的研究具有长远意义。本文以湖北省竹山县溢水镇东川苗圃、文峰乡肖家垭、德胜镇王家湾生产的肚倍为样品,每隔10天采摘一次,称重并测定其主要成分的含量,直至虫瘿成熟爆裂。经测定,3个产地的肚倍含有丰富的鞣质(约70.0%)、游离没食子酸(约5.0%)、1,2,3,4,6-五-O-没食子酰-β-葡萄糖(β-PGG,约6.0%)、可溶性总糖(约8.2%)、氨基酸(约7.5%)等,在不同的生长期,这些主要成分的含量无大的差异,而且主要的几种重金属元素铁(Fe)、锌(Zn)、铜(Cu)、钡(Ba)、铅(Pb)和砷(As)在生长过程中也不会累积,不影响采摘时间。综合考虑肚倍的生长情况和经济价值,肚倍适宜在其个头最大,即体积基本不再增长且未爆裂、无霉烂时采摘。

关键词：肚倍成分含量采摘

An improved phase measurement method of integrated pulse profile for pulsar

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Science China(Technological Sciences) 2011年第9期54卷 2263-2270页

作者： ZHANG hua xu LuPing School of Electronic Engineering Xidian University Xi' an 710071 China

Integrated profile is one of the basic characteristic of X-ray pulsar. Gaussian function fit is used to model the components of X-ray pulsar profile, and it is combined with Poisson distribution model of X-ray pulsar to analyze Cramer-Rao low bound （CRLB） of phase, phase rate estimation and relation between CRLB and profile components. Then, a time domain method using minimum entropy is proposed for profile phase and phase rate estimation, and its effectiveness is explained using simulation examples.

关键词： pulsars phase measurement Cramer-Rao minimum entropy

Strong Coupled Magnetic and Electric Ordering in Monolayer of Metal Thio(seleno)phosphates

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Chinese Physics Letters 2021年第7期38卷 145-150页

作者： Chenqiang hua hua Bai Yi zheng Zhu-An xu Shengyuan A.Yang Yunhao Lu Su-huai Wei Zhejiang Province Key Laboratory of Quantum Technology and Device State Key Laboratory of Silicon MaterialsDepartment of PhysicsZhejiang UniversityHangzhou 310027China Research Laboratory for Quantum Materials Singapore University of Technology and DesignSingapore 487372Singapore Beijing Computational Science Research Center Beijing 100193China

The coupling between electric ordering and magnetic ordering in two-dimensional(2D)materials is important for both fundamental research of 2D multiferroics and future development of magnetism-based information storage and ***,we introduce a scheme for realizing a magnetic phase transition through the transition of electric *** take CuMoP_(2)S_(6) monolayer as an example,which is a member of the large 2D transition-metal chalcogen-phosphates *** on first-principles calculations,we find that it is a multiferroic with unprecedented characters,namely,it exhibits two different phases:an antiferroelectric-antiferromagnetic phase and a ferroelectric-ferromagnetic phase,in which the electric and magnetic orderings are strongly ***,the electric polarization is out-of-plane,so the magnetism can be readily switched by using the gate electric *** finding reveals a series of 2D multiferroics with special magnetoelectric coupling,which hold great promise for experimental realization and practical applications.

关键词： ferroelectric coupling transition

Effects of Nb on microstructure and wear resistance of Fe-Cr-C-B surfacing alloy

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Journal of Iron and Steel Research International 2018年第2期25卷 243-251页

作者： Jian Gou zheng-jun Liu hua Jia Department of Material Science and Engineering ShenyangUniversity of Technology Shenyang 110870 LiaoningChina

The influence of Nb on the microstructure and wear resistance of the surfacing layer was investigated by using the Fe-based flux-cored wire in the Fe-Cr-C-B system. The microstructure, microhardness and wear resistance properties of the samples were investigated by X-ray diffraction, scanning electron microscopy, microhardness testing and abrasive wear testing, respectively. The results indicate that microstructures of the alloy are composed of martensite, retained austenite, M23（C,B）6 and NbC. Boride M23（C,B）6 is distributed along the grain boundaries, while NbC in shape-regular quadrilateral is distributed in martensite. The microhardness is distributed from the substrate to the surfacing layer gradiently. NbC significantly improved the wear resistance of surfacing layer.

关键词： Flux-cored wire Surfacing layer Microhardness Microstructure Wear resistance

Aldehyde oxidase mediated enantioselective metabolic health risk of dinotefuran

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Science China Chemistry 2024年第6期67卷 2079-2091页

作者： Liwei xu Xinxin xu hua Kuang Chuanlai xu Xiaoling Wu State Key Laboratory of Food Science and Resources Jiangnan UniversityWuxi214122China International Joint Research Laboratory for Biointerface and Biodetection and School of Food Science and Technology Jiangnan UniversityWuxi214122China Collaborative Innovation center of Food Safety and Quality Control in Jiangsu Province Jiangnan UniversityWuxi214122China

Chiral pollutants often pose significant differential environmental health *** this study,the biotransformation of chiral dinotefuran(DIN)and its enantioselective metabolic toxicity mechanisms have been systemically ***,reversedphase chromatography-high resolution mass spectrometry was developed to quantify the content of DIN R/S chiral enantiomer with pg level sensitivity,revealing a lower elimination rate constant(K_(e))of S-DIN(0.730 h^(-1))than R-DIN(0.746 h^(-1)).Secondly,the interaction mechanism between DIN metabolism and important endogenous bioactive molecules,such as aldehyde oxidase(AOX)and neurotransmitters,was *** DIN nitro-group was converted into a guanidine group by the reducing site of nearby flavin adenine dinucleotide(FAD)in AOX with the preferred higher affinity of ***,the endogenous tryptophan(Trp)aldehyde metabolic intermediate,5-hydroxyindoleacetaldehyde(5-HIAL),provides a persistent electron donor for DIN reduction via the oxidation-catalyzed site in AOX,resulting in remarkable up-regulation of monoamine neurotransmitters such as serotonin and ***,the higher level of neurotransmitters further mediated dysregulation of oxylipin homeostasis via the serotonergic pathway,where S-DIN exhibited more pronounced liver lipid damage and environmental health risk with the accumulated lipid biomarkers,oxidized triglyceride(OxTG)and oxidized sphingomyelin(OxSM).This study elucidates the AOX-mediated enantioselectivity metabolic pathway of DIN,providing a new analytical method for chiral pollutants and paves the way for their health risk assessments.

关键词： neonicotinoid dinotefuran enantiomer aldehyde oxidase metabolomics health risk

Application of MMC with Embedded Energy Storage for Overvoltage Suppression and Fault Ride-through Improvement in Series LCCMMC Hybrid HVDC System

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Journal of Modern Power Systems and Clean Energy 2023年第3期11卷 1001-1013页

作者： Xiaodong Li zheng xu Zheren Zhang Department of Electrical Engineering Zhejiang UniversityHangzhou 310027China IEEE

The series line-commutated converter(LCC)and modular multilevel converter(MMC)hybrid high-voltage direct current(HVDC)system provides a more economical and flexible alternative for ultra-HVDC(UHVDC)transmission,which is the so-called Baihetan-Jiangsu HVDC(BJ-HVDC)project of *** one LCC and two MMCs(1+2)operation mode,the sub-module(SM)capacitors suffer the most rigorous overvoltage induced by three-phase-to-ground fault at grid-side MMC and valve-side single-phase-to-ground fault in internal *** order to suppress such huge overvoltage,this paper demonstrates a novel alternative by employing the MMC-based embedded battery energy storage system(MMC-BESS).Firstly,the inducements of SM overvoltage are ***,coordinated with MMC-BESS,new fault ride-through(FRT)strategies are proposed to suppress the overvoltage and improve the FRT ***,several simulation scenarios are carried out on PSCAD/*** overvoltage suppression is verified against auxiliary device used in the BJ-HVDC project in a monopolar BJ-HVDC ***,the proposed FRT strategies are validated in the southern Jiangsu power grid of China based on the planning data in the summer of *** results show that the MMC-BESS and proposed FRT strategies could effectively suppress the overvoltage and improve the FRT capability.

关键词： Line-commutated converter(LCC) modular multilevel converter(MMC) MMC-based embedded battery energy storage system(MMC-BESS) fault ride-through(FRT)capability overvoltage suppression

Aquaporin-1 down regulation associated with inhibiting cell viability and inducing apoptosis of human lens epithelial cells

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International Journal of Ophthalmology(English edition) 2016年第1期9卷 15-20页

作者： Hong-hua zheng Guo-Xing xu Jian Guo Li-Cheng Fu Yao Yao Fujian Institute of Ophthalmology the First Affiliated Hospital of Fujian Medical University

AIM：To investigate the role of Aquaporin-1（AQP-1）in lens epithelial cells（LECs）and its potential target ***-1 is specifically expressed in LECs of eyes and is significant for lens homeostasis and transparency ***,AQP-1 expression in LECs was investigated to evaluate its influence on cell survival in association with its potential role in cataract formation.·M ETHODS：LECs were transfected with lentivirus carrying AQP-1 small interfering RNA（si RNA）.Real-time polymerase chain reaction（PCR）and Western blotting were conducted to detect AQP-1 expression in LECs from different ***,cell counting kit-8（CCK-8）assay and flow cytometry were performed to measure LEC proliferation and apoptosis,respectively.·RESULTS：AQP-1 expression was significantly reduced in LECs,both at m RNA and protein levels（〈0.05）,after si RNA *** cell viability was detected by CCK-8 assay in LECs with si RNA interference,compared to control cells（〈0.05）.The apoptosis rate significantly increased in cells after si RNA interference（〈0.05）.·CONCLUSION：The decreased cell viability following AQP-1 down regulation is largely due to its induction of apoptosis of ***-1 reduction might lead to changes of physiological functions in LECs,which might be associated with the occurrence and development of cataracts.

关键词： Aquaporin-1 small interfering RNA lensepithelial cells proliferation apoptosis cell counting kit-8 flow cytometry

Quasi-sure Flows Associated with Vector Fields of Low Regularity

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Chinese Annals of Mathematics,Series B 2014年第1期35卷 51-68页

作者： Siyan xu hua ZHANG Faculty of Sciences Ningbo University School of Statistics Jiangxi University of Finance and Economics

The authors construct a solution U_t(x) associated with a vector field on the Wiener space for all initial values except in a 1-slim set and obtain the 1-quasi-sure flow property where the vector field is a sum of a skew-adjoint operator not necessarily bounded and a nonlinear part with low regularity,namely one-fold ***,the equivalence of capacities under the transformations of the Wiener space induced by the solutions is obtained.

关键词： Quasi-sure flows Abstract Wiener space Low regularity

Circ_0004592:An auxiliary diagnostic biomarker for gastric cancer

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World Journal of Gastrointestinal Oncology 2024年第6期16卷 2757-2768页

作者： Shan Kong Yan-hua xu Ming zheng Shao-Qing Ju Heng-Chuan Shi Department of Laboratory Medicine Jiangsu Province Official HospitalNanjing 210000Jiangsu ProvinceChina Department of Laboratory Medicine Northern Jiangsu People’s HospitalYangzhou 225000Jiangsu ProvinceChina Department of Laboratory Medicine The Affiliated Hospital of Nantong UniversityNantong 226001Jiangsu ProvinceChina

BACKGROUND Gastric cancer(GC)has a high mortality rate,and robust diagnostic biomarkers are currently ***,the clinical relevance of circular RNAs(circRNAs)as GC biomarkers remains largely *** To evaluate the potential of novel circRNA circ_0004592 in the early screening and prognosis of *** High-throughput sequencing of circRNAs was performed to screen for potential target ***_0004592 expression was examined in GC tissues,cells,and *** samples were collected from healthy subjects’patients,as well as from patients with benign lesions,precancerous lesions,and GC,whereafter the diagnostic accuracy of circ_0004592 was *** correlation between circ_0004592 levels in plasma and clinicopathological data of patients with GC was further *** Circ_0004592 was upregulated in both the tissue and plasma of patients with ***,circ_0004592 expression was higher in patients with precancerous lesions than in healthy controls while being highest in patients with *** the same patient,the postoperative plasma level of circ_0004592 was lower than that in the preoperative ***,circ_0004592 level was significantly correlated with tumor differentiation,tumor depth,and lymph node *** area under the curve(AUC)of plasma circ_0004592 exhibited high sensitivity and specificity for differentiating patients with GC from healthy *** based on circ_0004592,carcinoembryonic antigen,and cancer antigen 199 achieved a superior AUC and was highly *** Plasma circ_0004592 may represent a potential non-invasive auxiliary diagnostic biomarker for patients with GC.

关键词： Biomarker Circular RNA Diagnosis Gastric cancer Plasma