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Sine oculis homeobox homolog family function in gastrointestinal cancer:Progression and comprehensive analysis

World Journal of Clinical Oncology 2025年第1期16卷 10-24页

作者： yang-zheng Lan zheng Wu Wen-Jia Chen Xin-Ning Yu Hua-Tao Wu Jing Liu Department of The Breast Center Cancer Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina Department of General Surgery First Affiliated Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina

The sine oculis homeobox homolog(SIX)family,a group of transcription factors characterized by a conserved DNA-binding homology domain,plays a critical role in orchestrating embryonic development and organogenesis across various organisms,including *** six distinct members,from SIX1 to SIX6,each member contributes uniquely to the development and differentiation of diverse tissues and organs,underscoring the versatility of the SIX *** or mutations in SIX genes have been implicated in a spectrum of developmental disorders,as well as in tumor initiation and progression,highlighting their pivotal role in maintaining normal developmental trajectories and cellular *** to target the transcriptional complex of the SIX gene family have emerged as a promising strategy to inhibit tumor *** the development of inhibitors targeting this gene family is still in its early stages,the significant potential of such interventions holds promise for future therapeutic ***,this review aimed to comprehensively explore the advancements in understanding the SIX family within gastrointestinal cancers,focusing on its critical role in normal organ development and its implications in gastrointestinal cancers,including gastric,pancreatic,colorectal cancer,and hepatocellular *** conclusion,this review deepened the understanding of the functional roles of the SIX family and explored the potential of utilizing this gene family for the diagnosis,prognosis,and treatment of gastrointestinal cancers.

关键词： Sine oculis homeobox homolog Gastrointestinal cancer Transcription factor Development Regulation Diagnosis Therapeutics

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Super-resolution processing of passive millimeter-wave images based on adaptive projected Landweber algorithm

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Journal of Systems Engineering and Electronics 2008年第4期19卷 709-716页

作者： zheng Xin yang Jianyu School of Electronic and Engineering Univ. of Electronic Science and Technology of China Chengdu 610054 P. R. China

Passive millimeter wave （PMMW） images inherently have the problem of poor resolution owing to limited aperture dimension. Thus, efficient post-processing is necessary to achieve resolution improvement. An adaptive projected Landweber （APL） super-resolution algorithm using a spectral correction procedure, which attempts to combine the strong points of all of the projected Landweber （PL） iteration and the adaptive relaxation parameter adjustment and the spectral correction method, is proposed. In the algorithm, the PL iterations are implemented as the main image restoration scheme and a spectral correction method is included in which the calculated spectrum within the passband is replaced by the known low frequency component. Then, the algorithm updates the relaxation parameter adaptively at each iteration. A qualitative evaluation of this algorithm is performed with simulated data as well as actual radiometer image captured by 91.5 GHz mechanically scanned radiometer. From experiments, it is found that the super-resolution algorithm obtains better results and enhances the resolution and has lower mean square error （MSE）. These constraints and adaptive character and spectral correction procedures speed up the convergence of the Landweber algorithm and reduce the ringing effects that are caused by regularizing the image restoration problem.

关键词： passive millimeter wave imaging super-resolution Landweber algorithm inverse problems spectral extrapolation.

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Reynolds-Averaged Navier-Stokes Equations Describing Turbulent Flow and Heat Transfer Behavior for Supercritical Fluid

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Journal of Thermal Science 2021年第1期30卷 191-200页

作者： yang zheng CHENG Xu zheng Xinghua CHEN Haisheng Institute of Engineering Thermophysics Chinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China Dalian National Laboratory for Clean Energy Chinese Academy of SciencesDalian 116023China Institute for Applied Thermofluidics Karlsruhe Institute of TechnologyKarlsruhe 76131Germany

Supercritical fluid has been widely applied in many industrial *** traditional Reynolds-averaged Navier-Stokes(RANS)equations are directly applied for turbulent flow and heat transfer of the supercritical fluid,ignoring turbulent effect of the thermal physical properties due to the intense *** paper deduces a set of Reynolds-averaged Navier-Stokes equations for supercritical fluid(SCF-RANS equations)to depict turbulent flow and heat transfer of the supercritical fluid taking all the physical parameters as *** SCF-RANS equations include many new correlation terms due to fluctuation of the thermal physical *** methods for the new correlation term have been discussed for closing the SCF-RANS *** of them have relatively mature models,while others are completely new and need profound physical theoretical analysis for proposing reasonable *** paper provides referable information for these new correlations as far as authors *** SCF-RANS equations not only provide the formulation special for flow and heat transfer of the supercritical fluid,but also represent the most sophisticate form of the RANS equations,for every involved physical property has been considered as variable without any simplification.

关键词： SCF-RANS equations supercritical fluid turbulence Reynolds-averaged Navier-Stokes equations

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Notes on Global Existence for the Nonlinear Schrdinger Equation Involves Derivative

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Acta Mathematica Sinica,English Series 2014年第10期30卷 1735-1747页

作者： Shi yang zheng School of Mathematics and Systems Science Beihang University

In this paper, we consider the scattering for the nonlinear SchrSdinger equation with small, smooth, and localized data. In particular, we prove that the solution of the quadratic nonlinear SchrSdinger equation with nonlinear term ｜u｜2 involving some derivatives in two dimension exists globally and scatters. It is worth to note that there exist blow-up solutions of these equations without derivatives. Moreover, for radial data, we prove that for the equation with p-order nonlinearity with derivatives, the similar results hold for P≥ =2d＋3/2d-1 and d ≥ 2, which is lower than the Strauss exponents.

关键词： SchrSdinger equation global well-posedness scatter small data quadratic

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On Compact Hermitian Manifolds with Flat Gauduchon Connections

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Acta Mathematica Sinica,English Series 2018年第8期34卷 1259-1268页

作者： Bo yang Fang yang zheng School of Mathematical Sciences Xiamen University Xiamen 361005 P. R. China Department of Mathematics Zhejiang Normal University Jinhua 321004 P. R. China Department of Mathematics The Ohio State University 231 West 18th Avenue Columbus OH 43210 USA

Given a Hermitian manifold （M-n,g）, the Gauduchon connections are the one parameter family of Hermitian connections joining the Chern connection and the Bismut connection. We will call△=（1-s/2）△c＋s/2△b the s-Gauduchon connection of M, where △c and △b are respectively the Chern and Bismut connections. It is natural to ask when a compact Hermitian manifold could admit a flat s-Gauduchon connection. This is related to a question asked by Yau. The cases with s = 0 （a flat Chern connection） or s = 2 （a flat Bismut connection） are classified respectively by Boothby in the 1950s or by the authors in a recent joint work with Q. Wang. In this article, we observe that if either s 〉 4＋2√3 ≈ 7.46 or s 〈 4- 2√3≈ 0.54 and s ≠ 0, then g is Kahler. We also show that, when n = 2, g is always Kahler unless s=2. Therefore non-Kahler compact Gauduchon fiat surfaces are exactly isosceles Hopf surfaces.

关键词： Hermitian manifolds Hermitian connections Kahler manifolds

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Nonnegative matrix factorization with Log Gabor wavelets for image representation and classification

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Journal of Systems Engineering and Electronics 2005年第4期16卷 738-745页

作者： zheng Zhonglong yang Jie Inst. of Image Processing and Pattern Recognition of Shanghai Jiaotong Univ. Shanghai 200030 P. R. China

Many problems in image representation and classification involve some form of dimensionality reduction. Nonnegative matrix factorization （NMF） is a recently proposed unsupervised procedure for learning spatially localized, partsbased subspace representation of objects. An improvement of the classical NMF by combining with Log-Gabor wavelets to enhance its part-based learning ability is presented. The new method with principal component analysis （PCA） and locally linear embedding （LIE） proposed recently in Science are compared. Finally, the new method to several real world datasets and achieve good performance in representation and classification is applied.

关键词： non-negative matrix factorization (NMF) Log Gabor wavelets principal component analysis locally linearembedding (LLE)

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CHAOTIC MOTIONS AND LIMIT CYCLE FLUTTER OF TWO-DIMENSIONAL WING IN SUPERSONIC FLOW

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Acta Mechanica Solida Sinica 2008年第5期21卷 441-448页

作者： Guoyong zheng Yiren yang Department of Applied Mechanics and Engineering Southwest Jiaotong University Chengdu 610031 China

Based on the piston theory of supersonic flow and the energy method, the flutter motion equations of a two-dimensional wing with cubic stiffness in the pitching direction are established. The aeroelastic system contains both structural and aerodynamic nonlinearities. Hopf bifurcation theory is used to analyze the flutter speed of the system. The effects of system parameters on the flutter speed are studied. The 4th order Runge-Kutta method is used to calculate the stable limit cycle responses and chaotic motions of the aeroelastic system. Results show that the number and the stability of equilibrium points of the system vary with the increase of flow speed. Besides the simple limit cycle response of period 1, there are also period-doubling responses and chaotic motions in the flutter system. The route leading to chaos in the aeroelastic model used here is the period-doubling bifurcation. The chaotic motions in the system occur only when the flow speed is higher than the linear divergent speed and the initial condition is very small. Moreover, the flow speed regions in which the system behaves chaos axe very narrow.

关键词： supersonic flow nonlinearity chaos limit cycle flutter two-dimensional wing

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New constructions for (multiparty) one-round key exchange with strong security

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Science China(Information Sciences) 2018年第5期61卷 332-337页

作者： zheng yang Junyu LAI School of Computer Science and Engineering Chongqing University of Technology Department of Computer Science University of Helsinki School of Aeronautics and Astronautics University of Electronic Science and Technology of China

Dear editor,One-round key exchange(ORKE)represents a special class of two-message key *** enables two parties to establish a shared session key within only one communication *** first merit of ORKE is its communication efficiency,particularly because two parties are able to simultaneously run the protocol ***,the messages of two session participants(in an ORKE protocol)are completely independent.

关键词： New constructions for multiparty Eph DDH PFS

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Symmetry Groups and Exact Solutions of New(4+1)-Dimensional Fokas Equation

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Communications in Theoretical Physics 2009年第5期51卷 876-880页

作者： yang zheng-zheng YAN Zhen-Ya Key Laboratory of Mathematics Mechanization Institute of Systems Science AMSS Chinese Academy of Sciences Beijing 100080 China Graduate School of the Chinese Academy of Sciences Beijing 100049 China

In this paper, we investigate symmetries of the new （4＋1）-dimensional Fokas equation, including point symmetries and the potential symmetries. We firstly employ the algorithmic procedure of computing the point symmetries. And then we transform the Fokas equation into a potential system and gain the potential symmetries of Fokas equation. Finally, we use the obtained point symmetries wave solutions and other solutions of the Fokas equation. and some constructive methods to get some doubly periodic In particular, some solitary wave solutions are also given.

关键词： Fokas equation point symmetry potential symmetry solitary wave solution reduced form

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Optimal opportunistic maintenance model of multi-unit systems

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Journal of Systems Engineering and Electronics 2013年第5期24卷 811-817页

作者： Zhijun Cheng zheng yang Bo Guo School of Information Systems and Management National University of Defense Technology

An opportunistic maintenance model is presented for a continuously deteriorating series system with economical de-pendence. The system consists of two kinds of units, which are respectively subjected to the deterioration failure described by Gamma process and the random failure described by Poisson process. A two-level opportunistic policy defined by three decision parameters is proposed to coordinate the different maintenance actions and minimize the long-run maintenance cost rate of the system. A computable expression of the average cost rate is established by using the renewal property of the stochastic process of the maintained system state. The optimal values of three deci- sion parameters are derived by an iteration approach based on the characteristic of Gamma process. The behavior of the proposed policy is illustrated through a numerical experiment. Comparative study with the widely used corrective maintenance policy demonstrates the advantage of the proposed opportunistic maintenance method in significantly reducing the maintenance cost. Simultane- ously, the applicable area of this opportunistic model is discussed by the sensitivity analysis of the set-up cost and random failure rate.

关键词： opportunistic maintenance policy multi-unit system economical dependence Gamma process continuously deterio- ration.

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