检索结果-南通市图书馆

维普期刊数据库

Next-generation probiotic candidates targeting intestinal health in weaned piglets: Both live and heat-killed Akkermansia muciniphila prevent pathological changes induced by enterotoxigenic Escherichia coli in the gut

在线全文

学校读者我要写书评

暂无评论

Animal Nutrition 2024年第02期17卷 110-122页

作者： Cong lan Hua Li yuqing Shen Yang Liu Aimin Wu Jun He Jingyi Cai Gang Tian Xiangbing mao Zhiqing huang Bing yu Ping zheng Jie yu Junqiu Luo Hui Yan yuheng Luo Key Laboratory for Animal Disease-Resistance Nutrition of Ministry of Education of China Key Laboratory for Animal Disease-Resistance Nutrition and Feed of Ministry of Agriculture of ChinaKey Laboratory of Animal Disease-Resistant Nutrition of Sichuan ProvinceEngineering Research Center of Animal Disease-Resistance Nutrition Biotechnology of Ministry of Education of ChinaAnimal Nutrition InstituteSichuan Agricultural University

The use of next-generation probiotics （NGP） in pigs for combating diseases has been subject to limited *** we explored the potential of a well-known NGP candidate Akkermansia muciniphila targeting pig gut *** the first screening experiment,we found that the abundance of *** peaked at 14 d old but decreased at weaning （21 d old;Pline every other day;the HA and LA groups were gavaged every other day with 1×1010CFU/5 m L and 5×10～8CFU/5 mL live ***,respectively;and the HIA and LIA groups were gavaged every other day with 1×1010CFU/5 mL and 5×10～8CFU/5 mL heat-killed ***,*** d 29,pigs in the CON group were randomly and equally divided into two groups,one of which was named the enterotoxigenic Escherichia coli （ETEC） group,and all groups except CON received a 5-d ETEC *** supplementation of *** numerically reduced the diarrhea rate of weaned pigs compared to the pigs that only received the ETEC challenge （P=0.57）,but the LIA group had a higher diarrhea rate than the CON group （P<0.05）.Consistent with this,the supplementation of *** improved the small intestinal morphology and structure,proportion of CD4+T lymphocytes in the blood,as well as the expression of genes related to intestinal barrier and antioxidant indices of pigs with ETEC challenge,especially for the LA group （P<0.05）.Meanwhile,*** supplementation reduced the expression of ETEC virulence factor genes in the ileum and colon of pigs challenged by ETEC （P<0.05）.Therefore,*** may protect the intestinal health of weaned piglets from damage caused by

关键词： Akkermansia muciniphila Weaned piglet Enterotoxigenic Escherichia coli challenge Intestinal health

Optical Sensor with Wide Range and High Sensitivity for Internal Magnetic Field Detection of Transformer

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

CSEE Journal of Power and Energy Systems 2024年第5期10卷 2230-2244页

作者： Meng huang Wei zheng Tong Ji mao Ji Tianjiao Pu Bo Qi State Key Laboratory of Alternate Electrical Power System with Renewable Energy Sources North China Electric Power UniversityBeijing 102206China Beijing Key Laboratory of High Voltage&EMC North China Electric Power UniversityBeijing 102206China China Electric Power Research Institute Beijing 100192China

The deterioration of winding defects is one of the important causes of power transformer fires and even explosion *** change of leakage magnetic field distribution is the most direct response to winding *** there are few sensors suitable for online measurement of the internal magnetic field of *** on the Faraday magneto-optical effect,a magnetic field sensor with wide range and high sensitivity is proposed in this paper,which is suitable for the interior use of *** straight-through optical structure with interior polarizer is adopted,and the sensor has a measurement range of 1.5 T and a sensitivity of 1 *** also possesses a small size,with a length of about 30 mm after *** influence mechanism of vibration and temperature is revealed through theoretical analysis and numerical *** is proposed to filter out the interference of vibration by characteristic frequency analysis and to compensate for temperature by a two-probe *** anti-interference test verifies the effectiveness of this method,and it can reduce the error from 80.56%to 2.63%under the combined interference of vibration and temperature.

关键词： Anti-interference Bessel function Faraday magneto-optical effect leakage magnetic field transformer two-probe structure

All-trans retinoic acid alleviates transmissible gastroenteritis virus-induced intestinal inflammation and barrier dysfunction in weaned piglets

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Animal Science and Biotechnology 2024年第3期15卷 1131-1144页

作者： Junning Pu Daiwen Chen Gang Tian Jun He Ping zheng Zhiqing huang Xiangbing mao Jie yu yuheng Luo Junqiu Luo Hui Yan Aimin Wu Bing yu Institute of Animal Nutrition Sichuan Agricultural UniversityChengdu 611130SichuanPeople’s Republic of China Key Laboratory of Animal Disease-Resistance Nutrition Ministry of EducationMinistry of Agriculture and Rural AffairsKey Laboratory of Sichuan Province611130 ChengduSichuanPeople’s Republic of China

Background Transmissible gastroenteritis virus(TGEV)is one of the main pathogens causing severe diarrhea of *** pathogenesis of TGEV is closely related to intestinal ***-trans retinoic acid(ATRA)is the main active metabolite of vitamin A,which has immunomodulatory and anti-inflammatory ***,it is unclear whether ATRA can alleviate TGEV-induced intestinal inflammation and barrier dysfunction in *** study aimed to investigate the effects of ATRA on growth performance,diarrhea,intestinal inflammation and intesti-nal barrier integrity of TGEV-challenged *** In a 19-d study,32 weaned piglets were randomly divided into 4 treatments:Control group(basal diet),TGEV group(basal diet+TGEV challenge),TGEV+ATRA5 group(basal diet+5 mg/d ATRA+TGEV challenge)and TGEV+ATRA15 group(basal diet+15 mg/d ATRA+TGEV challenge).On d 14,piglets were orally administered TGEV or the sterile *** Feeding piglets with 5 and 15 mg/d ATRA alleviated the growth inhibition and diarrhea induced by TGEV(Plin A(sIgA)(Pling pathway related genes(TLR3,TLR4,RIG-I,MyD88,TRIF and MAVS)and the phosphorylation level of nuclear factor-κB-p65(NF-κB p65),and

关键词： All-trans retinoic acid Inflammation Intestinal barrier Piglets Transmissible gastroenteritis virus

维普期刊数据库

Revealing proton-coupled exchange mechanism in aqueous ion-exchange synthesis of nickel-rich layered cathodes for lithium-ion batteries

在线全文

学校读者我要写书评

暂无评论

eScience 2024年第4期4卷 103-109页

作者： yu-Hong Luo Qing-lin Pan Han-Xin Wei Ying-De huang Pei-Yao Li lin-Bo Tang Zhen-yu Wang Cheng Yan Jing mao Ke-Hua Dai Qing Wu Xia-Hui Zhang Jun-Chao zheng School of Materials Science and Engineering Central South UniversityChangsha 410083China School of Metallurgy and Environment Central South UniversityChangsha 410083China Engineering Research Center of the Ministry of Education for Advanced Battery Materials Central South UniversityChangsha 410083China School of Mechanical Medical and Process EngineeringQueensland University of TechnologyBrisbane 4001Australia School of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450001China College of Chemistry Tianjin Normal UniversityTianjin 300387China School of Information and Network Center Central South University Changsha 410083China

Ion exchange is a promising synthetic method for alleviating severe cation mixing in traditional layered oxide materials for lithium-ion batteries,leading to enhanced structural ***,the underlying mechanisms of ion exchange are still not fully *** a fundamental study of the ion-exchange mechanism is needed for achieving the controllable synthesis of layered oxides with a stable ***,we thoroughly unearth the underlying mechanism that triggers the ion exchange of Ni-rich materials in aqueous solutions by examining time-resolved structural evolution combined with theoretical *** results reveal that the reaction pathway of ion exchange can be divided into two steps:protonation and *** proton is the key to achieving charge balance in the ion exchange process,as revealed by X-ray adsorption spectroscopy and inductive coupled plasma *** addition,the intermediate product shows high lattice distortion during ion exchange,but it ends up with a most stable product with high lattice *** apparent discrepancies in lattice energy between materials before and after ion exchange emphasize the importance of synthetic design in structural *** work provides new insights into the ion-exchange synthesis of Ni-rich oxide materials,which advances the development of cathode materials for high-performance lithium-ion batteries.

关键词： Ion exchange Reaction mechanisms Proton-coupledNi-rich oxides Protonation Lithiation Lithium-ion batteries

Effect of magnetic resonance imaging in liver metastases

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第1期30卷 112-114页

作者： Xing-Liang huang Xiao-Dong Wang Zhao-Miao Gong Yan-Feng zheng Jing-Xin mao Department of Science and Education Dianjiang People's Hospital of ChongqingChongqing 408399China Department of Science and Industry Chongqing Medical and Pharmaceutical CollegeChongqing 400030China

This letter to the editor is a commentary on a study titled"Liver metastases:The role of magnetic resonance imaging."Exploring a noninvasive imaging evaluation system for the biological behavior of hepatocellular carcinoma(HCC)is the key to achieving precise diagnosis and treatment and improving *** review summarizes the role of magnetic resonance imaging in the detection and evaluation of liver metastases,describes its main imaging features,and focuses on the added value of the latest imaging tools(such as T1 weighted in phase imaging,T1 weighted out of phase imaging;diffusion-weighted imaging,T2 weighted imaging).In this study,I investigated the necessity and benefits of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid for HCC diagnostic testing and prognostic evaluation.

关键词： Liver metastases Magnetic resonance imaging Liver-specific contrast agents Gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid Hepatocellular carcinoma Hepatobiliary contrast agents

Hollow Multishelled Structure: Synthesis Chemistry and Application

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2024年第3期40卷 346-393页

作者： mao Dan WANG Chao LI Wei ZHOU Liang LIU Jian zheng Zjian ZHAO Yong CAO An-min WANG Shutao huang Jiaxing HUO Fengwei CHEN Hongyu MAI Liqiang yu Ranbo WANG Lianzhou LU yunfeng yu Chengzhong YANG Qihua YANG Zhenzhong ZENG Hua Chun ZHAO Hujun TANG Zhiyong ZHAO Dongyuan WANG Dan State Key Laboratory of Biochemical Engineering Institute of Process EngineeringChineseAcademy of SciencesBeijing 100190P.R.China Key Laboratory of Biopharmaceutical Preparation and Delivery Chinese Academy of SciencesBejing 100190P.R.China School of Fashion and Textiles The Hong Kong Polytechnic UniversityHong Kong SARP.R.China Department of Chemistry Fudan UniversityShanghai 200433P.R.China State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070P.R.China State Key Laboratory of Catalysis Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023P.R.China School of Chemistry Beihang UniversityBejing 100191P.R.China CAS Key Laboratory of Molecular Nanostructure and Nanotechnology and Beijing National Laboratory for Molecular Sciences Institute of ChemistryChinese Academy of SciencesBeijing 100190P.R.China CAS Key Laboratory of Bio-inspired Materials and Interfacial Science Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190P.R.China School of Engineering Westlake UniversityHangzhou 310024P.R.China School of Flexible Electronics(Future Technologies) Nanjing Tech UniversityNanjing 211816P.R.China School of Science Westlake UniversityHangzhou 310024P.R.China School of Materials Science and Engineering Wuhan University of TechnologyWuhan 430070P.R.China School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083P.R.China School of Chemical Engineering and Australian Institute for Bioengineering and Nanotechnology The University of QueenslandBrisbaneQueensland 4072Australia College of Life Science and Technology Bejing University of Chemical TechnologyBejing 100029P.R.China School of Chemistry and Molecular Engineering East China Normal UniversityShanghai 200241P.R.China College of Life Sciences Zhejiang Normal UniversityJinhua 321004P.R.China Department of Chemical Engineering Tsinghua UniversityBeijing 100

Hollow multishelled structure(HoMS),a promising and complex multifunctional structural system,features at least two shells that are separated by internal *** unique structure endows it with numerous advantages including low density,high loading capacity,large specific surface area,facilitated mass transport,and multiple spatial confinement *** the past twenty years,benefiting from the booming development of synthesis methods,various HoMS materials have been prepared and show promising applications in diverse areas.

关键词： Hollow multishelled structure Synthesis chemistry Energy storage Catalysis Electromagnetic wave absorption Drug delivery Sensor

Risk factors for renal outcomes in children with antineutrophil cytoplasmic antibody-associated vasculitis:a nationwide retrospective study in China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Pediatrics 2024年第5期20卷 506-516页

作者： Li-Wen Tan Jun-Li Wan Chun-Hua Zhu Hong Xu zheng-Kun Xia Li-Zhi Chen Xiao-Chuan Wu Fang Wang Xiao-Rong Liu Cheng-Guang Zhao Xiao-Zhong Li Jian-Hua mao Xiao-Wen Wang Wen-Yan huang yu-Hong Li Jian-Jiang Zhang Shi-Pin Feng Jun Yang Jiao-Jiao Liu Chun-lin Gao Li-Ping Rong lan-Jun Shuai Ke Xu He-Jia Zhang Qiu Li Ai-Hua Zhang Mo Wang Department of Nephrology Children’s Hospital of Chongqing Medical UniversityZhongshan 2nd Rd.136Chongqing400014China Ministry of Education Key Laboratory of Child Development and Disorders National Clinical Research Center for Child Health and DisordersChina International Science and Technology Cooperation Base of Child Development and Critical DisordersChildren’s Hospital of Chongqing Medical UniversityChongqingChina Chongqing Key Laboratory of Pediatrics Children’s Hospital of Chongqing Medical UniversityChongqingChina Department of Nephrology Children’s Hospital of Nanjing Medical University72 Guangzhou RoadNanjing210008China Department of Nephrology Children’s Hospital of Fudan UniversityNational Paediatric Medical Center of ChinaShanghaiChina Department of Pediatrics Jinling HospitalNanjing Medical UniversityNanjingChina Department of Pediatrics Jinling HospitalThe First School of Clinical MedicineSouthern Medical UniversityNanjingChina Department of Pediatrics Jinling HospitalMedical School of Nanjing UniversityNanjingChina Department of Pediatric Nephrology and Rheumatology The First Affiliated Hospital of Sun Yat-Sen UniversityGuangzhouChina Department of Pediatrics The Second Xiangya Hospital of Central South UniversityChangshaChina Department of Pediatrics Peking University First HospitalBeijingChina Department of Nephrology Beijing Children’s HospitalCapital Medical UniversityBeijing100045China National Center for Children’s Health BeijingChina Department of Pediatrics Shengjing Hospital of China Medical UniversityShenyangChina Department of Nephrology and Immunology Children’s Hospital of Soochow UniversitySuzhouChina Department of Nephrology Children HospitalZhejiang University School of MedicineHangzhouChina Department of Nephrology Wuhan Children’s Hospital(Wuhan Maternal and Child Healthcare Hospital)Tongji Medical CollegeHuazhong University of Science&TechnologyWuhanChina Department of Nephrology and Rheumatology Shanghai Children’s HospitalSchool

Background Pediatric antineutrophil cytoplasmic antibody-associated vasculitis(AAV)is a life-threatening systemic vasculitis featured by liability to renal ***,there are few studies on the risk factors and predictive models for renal outcomes of AAV in *** Data from 179 AAV children in multiple centers between January 2012 and March 2020 were collected *** risk factors and predictive model of end-stage renal disease(ESRD)in AAV were *** Renal involvement was the most typical manifestation(95.5%),and the crescent was the predominant pathological lesion(84.9%).The estimated glomerular filtration rate(eGFR)was evaluated in 114 patients,of whom 59.6%developed ESRD,and the median time to ESRD was 3.20 *** eGFR[P=0.006,odds ratio(OR)=0.955,95%confidence interval(CI)=0.924–0.987]and the percentages of global glomerulosclerosis(pGGS;P=0.018,OR=1.060,95%CI=1.010–1.112)were independent risk factors for ESRD of renal *** on the pGGS and eGFR at renal biopsy,we developed three risk grades of ESRD and one predictive *** Kaplan‒Meier curve indicated that renal outcomes were significantly different in different risk grades(Pline,the predictive model had higher accuracy(0.86 versus 0.58,P<0.001)and a lower coefficient of variation(0.07 versus 0.92)in external *** Renal involvement is the most common manifestation of pediatric AAV in China,of which more than half deteriorates into *** predictive model based on eGFR at renal biopsy and the pGGS may be stable and accurate in speculating the risk of ESRD in AAV children.

关键词： Antineutrophil cytoplasmic antibody End-stage renal disease Glomerulonephritis Pediatric nephrology Vasculitis

Acute primary angle closure during the Omicron outbreak

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2024年第7期17卷 1337-1343页

作者： Dong Fang Wang-Ting Li Jia Liang Lu Chen Ning-Xin Dou Hui-Yan zheng Can-Feng huang Ting Xie Yi-Jing Zhuang Peng-Feng Li Xing-Xing mao Shao-Chong Zhang Shenzhen Eye Hospital Jinan UniversityShenzhen Key Laboratory of OphthalmologyShenzhen 518040Guangdong ProvinceChina

AIM:To investigate Omicron’s impact on clinical presentation of acute primary angle closure(APAC)in ***:A consecutive case series with historical controls was conducted at Shenzhen Eye Hospital,the largest specialized hospital in Shenzhen,*** records from a two-month period during the Omicron pandemic(December 1,2022,to January 31,2023)were compared with records from two control groups(12/2018–1/2019 and 12/2021–1/2022)before *** with APAC were included,and the prevalence of APAC and demographic characteristics in Omicron-infected and noninfected patients were ***:Seventy-one(23.43%)out of 303 patients were diagnosed with APAC in the pandemic cohort,which was 2.98 and 2.61 times higher than that in control cohorts(7.87%in 2019,8.96%in 2022,P<0.001).The pandemic cohort has significantly higher Omicron-infected rate(78.87%vs 0 vs 0;P<0.001),lower proportion of glaucoma history(16.90%vs 42.86%vs 41.67%,P=0.005),higher surgical rate(95.77%vs 83.33%vs 78.57%,P=0.024),higher total medical costs and larger pupil diameter(5.63±0.15 vs 4.68±0.15 vs 4.69±0.22 mm,P<0.01).In 83%Omicron-infected patients,ocular symptoms appeared within 3d after systemic symptoms *** multivariate analysis,Omicron infection(P<0.001)was the only independent predictor of pupil ***:In the Omicron epidemic in China,there is an increase of prevalence and severity of APAC,particularly focusing on the first 3d following infection.

关键词： Omicron acute primary angle closure ocular symptoms

自主研发、协同创新对创新质量的影响——基于短期与长期创新质量视角

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

山西财经大学学报 2024年第8期46卷 16-31页

作者：俞立平黄梦亭毛征兵浙江工商大学统计与数学学院浙江杭州310018 浙江工商大学统计数据工程技术与应用协同创新中心浙江杭州310018 广州商学院管理学院广东广州510700

以高技术产业为例,分别采用面板数据模型、面板门槛模型和贝叶斯向量自回归模型研究自主研发、协同创新对短期与长期创新质量的影响规律及作用特征。结果表明:自主研发和协同创新对长期与短期创新质量均具有促进作用,且对长期创新质量... 详细信息

以高技术产业为例,分别采用面板数据模型、面板门槛模型和贝叶斯向量自回归模型研究自主研发、协同创新对短期与长期创新质量的影响规律及作用特征。结果表明:自主研发和协同创新对长期与短期创新质量均具有促进作用,且对长期创新质量的正向作用更大,另外自主研发对创新质量的影响要大于协同创新;自主研发和协同创新在影响创新质量方面的协调水平亟待提升;自主研发和协同创新的绩效均有待提高;当协同创新投入水平较高时,自主研发对创新质量的正向作用最大;自主研发在协同创新影响创新质量中的调节作用存在“最优区间”。

关键词：自主研发协同创新高技术产业短期创新质量长期创新质量

维普期刊数据库