检索结果-南通市图书馆

GS-orthogonalization OMP method for space target detection via bistatic space-based radar

Chinese Journal of Aeronautics 2024年第7期37卷 333-351页

作者： shuyu zheng Libing JIANG Qingwei YANG Yingjian ZHAO Zhuang WANG National Key Laboratory of Science and Technology on Automatic Target Recognition College of Electronic Science and TechnologyNational University of Defense TechnologyChangsha 410073China

A space-based bistatic radar system composed of two space-based radars as the transmitter and the receiver respectively has a wider surveillance region and a better early warning capability for high-speed targets,and it can detect focused space targets more flexibly than the monostatic radar system or the ground-based radar ***,the target echo signal is more difficult to process due to the high-speed motion of both space-based radars and space *** be specific,it will encounter the problems of Range Cell Migration(RCM)and Doppler Frequency Migration(DFM),which degrade the long-time coherent integration performance for target detection and localization *** solve this problem,a novel target detection method based on an improved Gram Schmidt(GS)-orthogonalization Orthogonal Matching Pursuit(OMP)algorithm is proposed in this ***,the echo model for bistatic space-based radar is constructed and the conditions for RCM and DFM are ***,the proposed GS-orthogonalization OMP method is applied to estimate the equivalent motion parameters of space ***,the RCM and DFM are corrected by the compensation function correlated with the estimated motion ***,coherent integration can be achieved by performing the Fast Fourier Transform(FFT)operation along the slow time direction on compensated echo *** simulations and real raw data results validate that the proposed GS-orthogonalization OMP algorithm achieves better motion parameter estimation performance and higher detection probability for space targets detection.

关键词： Bistatic space-based radar High-speed maneuvering space targets detection Range Cell Migration(RCM) Doppler Frequency Migration(DFM) Gram Schmidt(GS)-orthogonalization Orthogonal Matching Pursuit(OMP)algorithm

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Platycodin D inhibits angiogenic vascular mimicry in NSCLC by regulating the eIF4E-mediated RNA methylome

引用

Journal of Pharmaceutical Analysis 2024年第1期14卷 152-155页

作者： shuyu zheng Yanlin Xin Jiamin Lin Zejuan Xie Keyu Cheng Shanshan Wang Wenli Lu Hao Yang Tianming Lu Jun Li Ruogu Qi Yuanyuan Guo Department of Biochemistry and Molecular Biology School of Medicine&Holistic Integrative MedicineNanjing University of Chinese MedicineNanjing210023China Department of Neurosurgery The Second Affiliated HospitalZhejiang UniversityHangzhou310009China

The treatment of non-small cell lung cancer(NSCLC)remains a challenge due to tumor evolution during anti-angiogenesis therapies,in which the mechanism of vascular mimicry(VM)is believed to result in ineffective treatment[1].To conquer this challenge,substantial effort has recently been devoted to seeking out natural compounds on account of their multitarget *** a traditional herbal medicine,platycodin D(PD)is the major bioactive monomer derived from Platycodon grandiflorum(***)and is used as an expectorant for pulmonary disease in Asia[2].

关键词： NSCLC eIF4E treatment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

基于改进OMP算法的多目标高速机动检测方法

引用

北京航空航天大学学报 2024年第7期50卷 2265-2271页

作者：王阳张小宽马前阔郑舒予宗彬锋徐嘉华空军工程大学研究生院西安710051 空军工程大学防空反导学院西安710051 国防科技大学ATR国防科技重点实验室长沙410073

针对多目标高速机动检测问题,提出了一种基于改进正交匹配追踪(OMP)算法的多目标检测方法。根据高速机动目标运动特性建立信号模型;利用改进OMP算法对脉冲压缩后的回波信号进行运动参数估计;构建相位补偿函数对距离徙动和多普勒徙动进... 详细信息

针对多目标高速机动检测问题,提出了一种基于改进正交匹配追踪(OMP)算法的多目标检测方法。根据高速机动目标运动特性建立信号模型;利用改进OMP算法对脉冲压缩后的回波信号进行运动参数估计;构建相位补偿函数对距离徙动和多普勒徙动进行校正;通过快速傅里叶变换(FFT)完成相参积累,实现对多目标的检测。改进算法适用于多目标高速机动检测场景,可有效避免盲速旁瓣现象及信号交叉项的影响,且具有参数估计精度高和抗噪声能力强等优点。仿真实验验证了改进算法的有效性与可靠性。

关键词：高速机动目标改进正交匹配追踪算法距离徙动多普勒徙动相参积累

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A modified OMP method for multi-orbit three dimensional ISAR imaging of the space target

引用

Journal of Systems Engineering and Electronics 2023年第4期34卷 879-893页

作者： JIANG Libing zheng shuyu YANG Qingwei YANG Peng WANG Zhuang Science and Technology on Automatic Target Recognition National University of Defense TechnologyChangsha410073China Xi’an Satellite Measurement and Control Center Xi’an 710600China

The conventional two dimensional(2D)inverse synthetic aperture radar(ISAR)imaging fails to provide the targets'three dimensional(3D)*** this paper,a 3D ISAR imaging method for the space target is proposed based on mutliorbit observation data and an improved orthogonal matching pursuit(OMP)***,the 3D scattered field data is converted into a set of 2D matrix by stacking slices of the 3D data along the elevation direction ***,an improved OMP algorithm is applied to recover the space target's amplitude information via the 2D matrix ***,scattering centers can be reconstructed with specific three dimensional *** simulations are provided to demonstrate the effectiveness and superiority of the proposed 3D imaging method.

关键词： three dimensional inverse synthetic aperture radar(3D ISAR)imaging space target improved orthogonal matching pursuit(OMP)algorithm scattering centers

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Parameter estimation of GTD model and RCS extrapolation based on a modified 3D-ESPRIT algorithm

引用

Journal of Systems Engineering and Electronics 2020年第6期31卷 1206-1215页

作者： zheng shuyu ZHANG Xiaokuan ZHAO Weichen ZHOU Jianxiong ZONG Binfeng XU Jiahua Air and Missile Defense College Air Force Engineering UniversityXi’an 710051China College of Economics Jilin University of Finance and EconomicsChangchun 130022China School of Electronics Science and Engineering National University of Defense TechnologyChangsha 410073China

The noise robustness and parameter estimation performance of the classical three-dimensional estimating signal parameter via rotational invariance techniques(3D-ESPRIT)algorithm are poor when the parameters of the geometric theory of the diffraction(GTD)model are estimated at low signal-to-noise ratio(SNR).To solve this problem,a modified 3D-ESPRIT algorithm is *** modified algorithm improves the parameter estimation accuracy by proposing a novel spatial smoothing ***,we make cross-correlation of the auto-correlation matrices;then by averaging the cross-correlation matrices of the forward and backward spatial smoothing,we can obtain a novel equivalent spatial smoothing *** formula of the modified algorithm is derived and the performance of this improved method is also *** we compare root-meansquare-errors(RMSEs)of different parameters and the locating accuracy obtained by different ***,radar cross section(RCS)of radar targets is *** results verify the effectiveness and superiority of the modified 3DESPRIT algorithm.

关键词： parameter estimation novel spatial smoothing scattering center geometric theory of diffraction(GTD)model radar cross section(RCS)extrapolation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

SynergyFinder Plus:Toward Better Interpretation and Annotation of Drug Combination Screening Datasets

引用

Genomics, Proteomics & Bioinformatics 2022年第3期20卷 587-596页

作者： shuyu zheng Wenyu Wang Jehad Aldahdooh Alina Malyutina Tolou Shadbahr Ziaurrehman Tanoli Alberto Pessia Jing Tang Research Program in Systems Oncology Faculty of MedicineUniversity of HelsinkiHelsinki 00290Finland

Combinatorial therapies have been recently proposed to improve the efficacy of anticancer treatment. The Synergy Finder R package is a software used to analyze pre-clinical drug combination datasets. Here, we report the major updates to the Synergy Finder R package for improved interpretation and annotation of drug combination screening results. Unlike the existing implementations, the updated Synergy Finder R package includes five main innovations. 1) We extend the mathematical models to higher-order drug combination data analysis and implement dimension reduction techniques for visualizing the synergy landscape. 2) We provide a statistical analysis of drug combination synergy and sensitivity with confidence intervals and P values. 3)We incorporate a synergy barometer to harmonize multiple synergy scoring methods to provide a consensus metric for synergy. 4) We evaluate drug combination synergy and sensitivity to provide an unbiased interpretation of the clinical potential. 5) We enable fast annotation of drugs and cell lines, including their chemical and target information. These annotations will improve the interpretation of the mechanisms of action of drug combinations. To facilitate the use of the R package within the drug discovery community, we also provide a web server at www.s *** as a user-friendly interface to enable a more fexible and versatile analysis of drug combination data.

关键词： SynergyFinder Drug combination Synergy modeling Drug discovery Drug combination sensitivity analysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

打印路径对3D打印混凝土构件力学性能的影响

引用

混凝土与水泥制品 2024年第7期 14-19,28页

作者：张学辉郑书玉陈雄姿安军海赵双双河北科技大学建筑工程学院河北石家庄050000

在3D打印混凝土配合比研究基础上,对打印路径进行了优化设计。采用三种路径打印成型构件,评估了打印路径对3D打印混凝土构件力学性能的影响,并分析了打印构件的力学各向异性,提出了力学各向异性系数,确定了最佳受力方向。此外,通过SEM... 详细信息

在3D打印混凝土配合比研究基础上,对打印路径进行了优化设计。采用三种路径打印成型构件,评估了打印路径对3D打印混凝土构件力学性能的影响,并分析了打印构件的力学各向异性,提出了力学各向异性系数,确定了最佳受力方向。此外,通过SEM分析了打印构件的层间界面对力学性能的影响。结果表明:3D打印混凝土构件在Z方向受力最大,打印路径优化后,可有效改善层间薄弱面;打印构件在层间界面处的水化产物未能充分填充,存在空隙、气泡、裂缝等缺陷,使打印构件的力学性能降低。

关键词： 3D打印混凝土路径优化力学性能层间薄弱面

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Role of CD36 in central nervous system diseases

引用

Neural Regeneration Research 2024年第3期19卷 512-518页

作者： Min Feng Qiang Zhou Huimin Xie Chang Liu Mengru zheng shuyu Zhang Songlin Zhou Jian Zhao School of Health Science and Engineering University of Shanghai for Science and TechnologyShanghaiChina Department of Orthopedic Oncology Second Affiliated Hospital of Naval Medical UniversityShanghaiChina Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology ProductsJiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury RepairCo-Innovation Center of NeuroregenerationNantong UniversityNantongJiangsu ProvinceChina Department of Stomatology Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina Medical College of Nantong University NantongJiangsu ProvinceChina

CD36 is a highly glycosylated integral membrane protein that belongs to the scavenger receptor class B family and regulates the pathological progress of metabolic ***36 was recently found to be widely expressed in various cell types in the nervous system,including endothelial cells,pericytes,astrocytes,and ***36 mediates a number of regulatory processes,such as endothelial dysfunction,oxidative stress,mitochondrial dysfunction,and inflammatory responses,which are involved in many central nervous system diseases,such as stroke,Alzheimer’s disease,Parkinson’s disease,and spinal cord ***36 antagonists can suppress CD36 expression or prevent CD36 binding to its ligand,thereby achieving inhibition of CD36-mediated pathways or ***,we reviewed the mechanisms of action of CD36 antagonists,such as Salvianolic acid B,tanshinone IIA,curcumin,sulfosuccinimidyl oleate,antioxidants,and small-molecule ***,we predicted the structures of binding sites between CD36 and *** sites can provide targets for more efficient and safer CD36 antagonists for the treatment of central nervous system diseases.

关键词： animal experiments antagonists CD36 antagonist central nervous system diseases clinical trial curcumin microRNA salvianolic acid B small-molecule drugs sulfosuccinimidyl oleate

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Strain-dependent alpha-synuclein spreading in Parkinson's disease and multiple system atrophy

引用

Neural Regeneration Research 2024年第12期19卷 2581-2582页

作者： shuyu Zhang Paul Lingor Department of Neurology School of MedicineUniversity Hospital rechts der IsarTechnical University of MunichMunichGermany Department of Neurology University Medical Center GöttingenGöttingenGermany Center for Biostructural Imaging of Neurodegeneration University Medical Center GöttingenGöttingenGermany

Parkinson's disease(PD) and atypical Parkinsonian syndromes,such as multiple system atrophy(MSA) and Dementia with Lewy bodies,are neurodegenerative movement disorders characterized by the accumulation of alphasynuclein(a-syn) *** a-syn aggregates propagate throughout the brain in a prion-like manner,where pathological a-syn recruits endogenous a-syn to form insoluble *** forms representing intermediates on the way to insoluble aggregates result in the most pronounced neurotoxic effects.

关键词： atrophy endogenous atypical

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An efficient physics-guided Bayesian framework for predicting ground settlement profile during excavations in clay

引用

Journal of Rock Mechanics and Geotechnical Engineering 2024年第4期16卷 1411-1424页

作者： Cong Tang shuyu He Wanhuan Zhou State Key Laboratory of Internet of Things for Smart City and Department of Civil and Environmental Engineering University of MacaoChina

Recently,the application of Bayesian updating to predict excavation-induced deformation has proven successful and improved prediction accuracy ***,updating the ground settlement profile,which is crucial for determining potential damage to nearby infrastructures,has received limited *** address this,this paper proposes a physics-guided simplified model combined with a Bayesian updating framework to accurately predict the ground settlement *** advantage of this model is that it eliminates the need for complex finite element modeling and makes the updating framework ***,the model is physically interpretable,which can provide valuable references for construction *** effectiveness of the proposed method is demonstrated through two field case studies,showing that it can yield satisfactory predictions for the settlement profile.

关键词： Bayesian updating Excavations Ground settlement profile Simplified model Uncertainty

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：