检索结果-南通市图书馆

A Novel Scheduling Framework for Multi-Programming Quantum Computing in Cloud Environment

在线全文

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2024年第5期79卷 1957-1974页

作者： Danyang zheng Jinchen Xv Feng Yue Qiming Du ZhihengWang zheng shan Information Engineering University Zhengzhou450001China

As cloud quantum computing gains broader acceptance,a growing quantity of researchers are directing their focus towards this ***,the rapid surge in demand for cloud-based quantum computing resources has led to a scarcity,which in turn hampers users from achieving optimal ***,cloud quantum computing service providers require a unified analysis and scheduling framework for their quantumresources and user jobs to meet the ever-growing usage *** paper introduces a new multi-programming scheduling framework for quantum computing in a cloud *** framework addresses the issue of limited quantum computing resources in cloud environments and ensures a satisfactory user *** introduces three innovative designs:1)Our framework automatically allocates tasks to different quantum backends while ensuring fairness among users by considering both the cloud-based quantum resources and the user-submitted tasks.2)Multi-programming mechanism is employed across different quantum backends to enhance the overall throughput of the quantum *** comparison to conventional task schedulers,our proposed framework achieves a throughput improvement of more than two-fold in the quantum cloud.3)The framework can balance fidelity and user waiting time by adaptively adjusting scheduling parameters.

关键词： Quantum computing scheduling multi-programming qubit mapping

HCRVD: A Vulnerability Detection System Based on CST-PDG Hierarchical Code Representation Learning

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2024年第6期79卷 4573-4601页

作者： Zhihui Song Jinchen Xu Kewei Li zheng shan School of Cyberspace Security Information Engineering UniversityZhengzhou450001China

Prior studies have demonstrated that deep learning-based approaches can enhance the performance of source code vulnerability detection by training neural networks to learn vulnerability patterns in code ***,due to limitations in code representation and neural network design,the validity and practicality of the model still need to be ***,due to differences in programming languages,most methods lack cross-language detection *** address these issues,in this paper,we analyze the shortcomings of previous code representations and neural *** propose a novel hierarchical code representation that combines Concrete Syntax Trees(CST)with Program Dependence Graphs(PDG).Furthermore,we introduce a Tree-Graph-Gated-Attention(TGGA)network based on gated recurrent units and attention mechanisms to build a Hierarchical Code Representation learning-based Vulnerability Detection(HCRVD)*** system enables cross-language vulnerability detection at the *** experiments show that HCRVD surpasses many competitors in vulnerability detection *** benefits from the hierarchical code representation learning method,and outperforms baseline in cross-language vulnerability detection by 9.772%and 11.819%in the C/C++and Java datasets,***,HCRVD has certain ability to detect vulnerabilities in unknown programming languages and is useful in real open-source *** shows good validity,generality and practicality.

关键词： Vulnerability detection deep learning CST-PDG code representation tree-graph-gated-attention network cross-language

Predictive value of total cholesterol to high-density lipoprotein cholesterol ratio for chronic kidney disease among adult male and female in Northwest China

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chronic Diseases and Translational Medicine 2024年第3期10卷 216-226页

作者： Yanli Liu Kang Lyu Shaodong Liu Jinlong You Xue Wang Minzhen Wang Desheng Zhang Yana Bai Chun Yin Min Jiang shan zheng School of Public Health Institute of Epidemiology and StatisticsLanzhou UniversityLanzhouGansuChina Workers'Hospital of Jinchuan Group Co.Ltd. JinchangGansuChina Wuwei People's Hospital WuweiGansuChina

Background: Studies have found that the ratio of total cholesterol to high-density lipoprotein cholesterol (TC/HDL-C) was associated with the development of chronic kidney disease (CKD). However, the relationship in different genders was rarely discussed. The aim of this study was to explore this relationship and assess its predictive power for both males and ***: Based on a prospective cohort platform in northwest China, 32,351 participants without CKD were collected in the baseline and followed up for approximately 5 years. Cox proportional hazard model and restricted cubic spline regression analysis were performed to investigate the association between TC, HDL-C, TC/HDL-C and CKD in adult female and male. The clinical application value of the indicators in predicting CKD was evaluated by the receiver operator characteristic ***: During a mean follow-up of 2.2 years, 484 males and 164 females developed CKD. After adjusted for relevant confounders, for every one standard deviation increase in TC, HDL-C and TC/HDL-C, the hazard ratios (HRs) and 95% confidence intervals (95% CIs) for CKD were 1.17 (1.05-1.31), 0.84 (0.71-0.99), and 1.15 (1.06-1.25) for males, 0.94 (0.78-1.13), 0.58 (0.35-0.95), and 1.19 (1.01-1.40) for females, respectively. The results also showed that TC, HDL-C, and TC/HDL-C were associated with CKD in a linear dose-response relationship. The TC/HDL-C had the largest area under the curve (AUC) compared to TC and HDL-C, and the AUC among the females was larger than that among ***: The TC/HDL-C was significantly associated with CKD in adult males and females and has better clinical value in predicting CKD than TC and HDL-C, especially in females.

关键词： chronic kidney disease gender Jinchang Cohort predictive value TC/HDL-C

Differentiation and immunosuppressive function of CD19^(+)CD24^(hi)CD27^(+) regulatory B cells are regulated through the miR-29a-3p/NFAT5 pathway

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2024年第5期23卷 472-480页

作者： Jin-Yang Li Tian-Shuo Feng Ji Gao Xin-Xiang Yang Xiang-Cheng Li Zhen-Hua Deng Yong-Xiang Xia zheng-shan Wu Hepatobiliary Center the First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029China Key Laboratory of Liver Transplantation Chinese Academy of Medical SciencesNanjing 210029China NHC Key Laboratory of Living Donor Liver Transplantation Nanjing Medical UniversityNanjing 210029China

Background: Regulatory B cells(Bregs) is an indispensable element in inducing immune tolerance after liver transplantation. As one of the microRNAs(miRNAs), mi R-29a-3p also inhibits translation by degrading the target mRNA, and yet the relationship between Bregs and mi R-29a-3p has not yet been fully explored. This study aimed to investigate the impact of miR-29a-3p on the regulation of differentiation and immunosuppressive functions of memory Bregs(m Bregs) and ultimately provide potentially effective therapies in inducing immune tolerance after liver transplantation. Methods: Flow cytometry was employed to determine the levels of Bregs in peripheral blood mononuclear cells. TaqMan low-density array miRNA assays were used to identify the expression of different miRNAs, electroporation transfection was used to induce mi R-29a-3p overexpression and knockdown, and dual luciferase reporter assay was used to verify the target gene of miR-29a-3p. Results: In patients experiencing acute rejection after liver transplantation, the proportions and immunosuppressive function of m Bregs in the circulating blood were significantly impaired. mi R-29a-3p was found to be a regulator of m Bregs differentiation. Inhibition of miR-29a-3p, which targeted nuclear factor of activated T cells 5(NFAT5), resulted in a conspicuous boost in the differentiation and immunosuppressive function of m Bregs. The inhibition of mi R-29a-3p in CD19~+ B cells was capable of raising the expression levels of NFAT5, thereby promoting B cells to differentiate into m Bregs. In addition, the observed enhancement of differentiation and immunosuppressive function of m Bregs upon mi R-29a-3p inhibition was abolished by the knockdown of NFAT5 in B cells. Conclusions: mi R-29a-3p was found to be a crucial regulator for m Bregs differentiation and immunosuppressive function. Silencing mi R-29a-3p could be a potentially effective therapeutic strategy for inducing immune tolerance after liver transplantation.

关键词： Regulatory B cells miR-29a-3p NFAT5 Liver transplantation

自然风险对农地资源配置效率的影响——基于风险应对能力差异视角

在线全文

学校读者我要写书评

暂无评论

资源科学 2024年第4期46卷 829-840页

作者：郑姗刘家成安宁南京农业大学经济管理学院南京210095 南京财经大学财政与税务学院南京210023

【目的】基于风险应对能力差异视角剖析自然风险对农地资源配置效率的影响及其机制,为改善农地资源配置效率提供理论依据与参考。【方法】基于2019年江苏、吉林和四川3省调查数据,利用多元回归模型分析自然风险对农地资源配置效率的影响... 详细信息

【目的】基于风险应对能力差异视角剖析自然风险对农地资源配置效率的影响及其机制,为改善农地资源配置效率提供理论依据与参考。【方法】基于2019年江苏、吉林和四川3省调查数据,利用多元回归模型分析自然风险对农地资源配置效率的影响,并在不同农户风险应对能力差异的视角下揭示自然风险对农地资源配置效率的影响机制。【结果】①现阶段中国仍存在农地资源配置效率低下的情况,自然风险可能降低农地资源配置效率,但存在一定的风险水平门槛,只有在自然风险上升到一定水平的情况下,自然风险才会降低农地资源配置效率。②高自然风险将抑制农地向经营效率较高的规模户流动,从而不利于农地资源配置效率的提升。规模户的风险应对能力在自然风险影响农地资源配置效率中发挥正向调节作用,即规模户的风险应对能力会弱化自然风险对农地资源配置效率的负向影响。【结论】提升农业经营主体的风险应对能力是提高农地资源配置效率的重要途径。政府应注重完善自然风险管理体系、解决禀赋约束问题以及规范农地流转市场,提高农业经营主体的自然风险应对能力,以有效提升农地资源配置效率。

关键词：自然风险农地资源配置效率风险应对 OP协方差 OLS模型

在线全文

学校读者我要写书评

暂无评论

药物非劣效临床试验剖析

中国新药杂志 2024年第11期33卷 1073-1081页

作者：郑青山上海中医药大学上海手201203

非劣效试验虽然历经数十年的实践,但至今仍有争议,尤其是国际相关指南在我国被误解和误用,需要重新认识。一般来说,非劣效检验只能回答受试药是否优于安慰剂,确认是否有效,难以获得与阳性对照药的比较性结论,即非劣效试验不产生真正的... 详细信息

非劣效试验虽然历经数十年的实践,但至今仍有争议,尤其是国际相关指南在我国被误解和误用,需要重新认识。一般来说,非劣效检验只能回答受试药是否优于安慰剂,确认是否有效,难以获得与阳性对照药的比较性结论,即非劣效试验不产生真正的非劣效结论,除非另设疗效差异没有临床意义的界值。其次,非劣效界值是疗效差异的可信区间限定值,属于统计学界值,但其大小的选择又归结为临床可接受的样本量多少。因此非劣效界值不能等同于与阳性对照药的疗效差异,更不是受试药与阳性对照药相比在临床上可接受的最大疗效损失。另外,非劣效试验在我国用于仿制药评价具有历史原因,由于不能产生比较性和可互换性结论,理应摒弃,应回归到临床终点的生物等效试验。本文从基本的分析原理出发,以国际指南为依据,采用实例阐明以上关键问题,试图提出一些解决方案,为我国非劣效试验的正确开展提供参考。

关键词：非劣效试验等效试验优效试验非劣效界值等效界值

胆道闭锁自体肝生存相关危险因素及预测模型研究进展

在线全文

学校读者我要写书评

暂无评论

中华小儿外科杂志 2024年第6期45卷 559-563页

作者：陈惠芬郑珊复旦大学附属儿科医院肝胆外科上海210008

胆道闭锁(biliary atresia,BA)是一种严重的婴幼儿肝胆系统疾病,是儿童肝移植最常见的指征。对患儿进行预后评估及选择个性化治疗对于BA的治疗至关重要,目前尚没有规范化的BA预后预测模型对BA患儿进行有效的预后评估。本文就胆道闭锁葛... 详细信息

胆道闭锁(biliary atresia,BA)是一种严重的婴幼儿肝胆系统疾病,是儿童肝移植最常见的指征。对患儿进行预后评估及选择个性化治疗对于BA的治疗至关重要,目前尚没有规范化的BA预后预测模型对BA患儿进行有效的预后评估。本文就胆道闭锁葛西术后自体肝生存的预后危险因素及相关预测模型的研究新进展进行综述。

关键词：胆道闭锁预后预测模型

在线全文

学校读者我要写书评

暂无评论

黄河下游平滩流量的模拟方法

水利学报 2024年第7期55卷 791-801页

作者：吴保生沈逸马子普郑珊清华大学水圈科学与水利工程全国重点实验室北京100084 清华大学水利部水圈科学重点实验室北京100084 清华大学水利水电工程系北京100084 天津大学建筑工程学院天津300072

在黄河流域水沙变异背景下,准确计算黄河下游平滩流量对于河道冲淤趋势预测与悬河治理十分重要。本文在比较分析已有多个黄河下游平滩流量计算方法基础上,首先建立了考虑非汛期水沙条件影响的平滩流量滞后响应模型,再提出了基于滞后响... 详细信息

在黄河流域水沙变异背景下,准确计算黄河下游平滩流量对于河道冲淤趋势预测与悬河治理十分重要。本文在比较分析已有多个黄河下游平滩流量计算方法基础上,首先建立了考虑非汛期水沙条件影响的平滩流量滞后响应模型,再提出了基于滞后响应模型和能量法的平滩流量模拟方法,结果表明:(1)小浪底运行后非汛期水沙条件发生了重要改变,已有研究提出的三种黄河下游平滩流量计算方法中,滑动平均法、滞后响应模型、能量法均无法有效模拟2000年后的黄河下游河道平滩流量。(2)建立了考虑非汛期水沙条件影响的滞后响应模型,以反映小浪底水库运行以来非汛期来水来沙条件的影响,虽然提高了平滩流量的模拟精度,但平滩流量平衡值的计算公式中部分参数差异较大,结构形式不稳定。(3)借鉴能量法的优点,改进了平滩流量平衡值计算公式,改进后的平滩流量计算方法不仅可反映全年来水来沙的影响,而且可同时反映以床沙中值粒径为代表的床面阻力的影响,新方法不仅具有一定的理论基础,而且提高了平滩流量的模拟精度。

关键词：黄河下游平滩流量来水来沙床沙中值粒径滞后响应能量法

市场结构与农业生产外包服务差别定价基于对规模户与普通户服务收费的考察

同方期刊数据库

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

农业技术经济 2024年第7期 4-25页

作者：郑旭媛郑姗林庆林福建农林大学经济与管理学院福州350028 南京农业大学经济管理学院南京210095

“一价法则”强调同质商品亦同价,但在农业生产外包服务市场中,存在外包服务供给主体对同一地区内不同规模农户制定了相同服务价格的现象,这背离了“一价法则”。本文从市场结构角度对此进行解释,并对这种市场结构的形成机制展开分析。... 详细信息

“一价法则”强调同质商品亦同价,但在农业生产外包服务市场中,存在外包服务供给主体对同一地区内不同规模农户制定了相同服务价格的现象,这背离了“一价法则”。本文从市场结构角度对此进行解释,并对这种市场结构的形成机制展开分析。研究表明:(1)当市场需求结构中普通户占比越高、市场供给不足或外地服务供给主体过少时,容易出现供给主体定价背离“一价”均衡的现象;(2)这种现象更可能出现在人均耕地较少、劳动力转移程度较高或资本禀赋贫乏的地区。研究拓展了“一价法则”的应用领域,强调了“一价法则”在解释农业生产外包服务市场价格形成的适用条件,对促进外包服务市场发育与土地规模化发展也具有重要政策涵义。

关键词：生产外包服务差别定价市场结构要素禀赋一价法则