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Novel Ag-bridged dual Z-scheme g-C_(3)N_(4)/BiOI/AgI plasmonic heterojunction: Exceptional photocatalytic activity towards tetracycline and the mechanism insight

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Journal of Environmental Sciences 2023年第9期131卷 123-140页

作者： Wenxia Wang Zhen Li Kailin Wu Guodong Dai Qingping Chen Lihua Zhou junxia zheng Liang Ma Guiying Li Wanjun Wang Taicheng An School of Biomedical and Pharmaceutical Sciences Guangdong University of TechnologyGuangzhou 510006China Guangdong Key Laboratory of Environmental Catalysis and Health Risk Control Guangdong-Hong Kong-Macao Joint Laboratory for Contaminants Exposure and HealthInstitute of Environmental Health and Pollution ControlGuangdong University of TechnologyGuangzhou 510006China Guangzhou Key lab of Clean Transport Energy and Chemistry Guangdong University of TechnologyGuangzhou 510006China Guangzhou Key Laboratory of Environmental Catalysis and Pollution Control Guangdong Technology Research Center for Photocatalytic Technology Integration and Equipment EngineeringSchool of Environmental Science and EngineeringGuangdong University of TechnologyGuangzhou 510006China

Rational design and synthesis of highly efficient and robust photocatalysts with positive exciton splitting and interfacial charge transfer for environmental applications is ***,aiming at overcoming the common shortcomings of traditional photocatalysts such as weak photoresponsivity,rapid combination of photo-generated carriers and unstable structure,a novel Ag-bridged dual Z-scheme g-C_(3)N_(4)/BiOI/AgI plasmonic heterojunction was successfully synthesized using a facile *** showed that Ag-AgI nanoparticles and three-dimensional(3D)BiOI microspheres were decorated highly uniformly on the 3D porous g-C_(3)N_(4) nanosheet,resulting in a higher specific surface area and abundant active *** optimized 3D porous dual Z-scheme g-C_(3)N_(4)/BiOI/Ag-AgI manifested exceptional photocatalytic degradation efficiency of tetracycline(TC)in water with approximately 91.8%degradation efficiency within 165 min,outperforming majority of the reported g-C_(3)N_(4)-based ***,g-C_(3)N_(4)/BiOI/Ag-AgI exhibited good stability in terms of activity and ***-depth radical scavenging and electron paramagnetic resonance(EPR)analyses confirmed the relative contributions of various *** analysis indicated that the improved photocatalytic performance and stability were ascribed to the highly ordered 3D porous framework,fast electron transfer of dual Z-scheme heterojunction,desirable photocatalytic performance of BiOI/AgI and synergistic effect of Ag ***,the 3D porous Z-scheme g-C_(3)N_(4)/BiOI/Ag-AgI heterojunction had a good prospect for applications in water *** current work provides new insight and useful guidance for designing novel structural photocatalysts for environment-related applications.

关键词： Three-dimensional Porous heterostructure Graphitic carbon nitride(g-C_(3)N_(4)) Dual Z-scheme heterojunction Tetracycline(TC)degradation Mechanism insight

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Novel benzothiazole derivatives target the Gac/Rsm two-component system as antibacterial synergists against Pseudomonas aeruginosa infections

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Acta Pharmaceutica Sinica B 2024年第11期14卷 4934-4961页

作者： Jun Liu Wenfu Wu Jiayi Hu Siyu Zhao Yiqun Chang Qiuxian Chen Yujie Li Jie Tang Zhenmeng Zhang Xiao Wu Shumeng Jiao Haichuan Xiao Qiang Zhang Jiarui Du Jianfu Zhao Kaihe Ye Meiyan Huang Jun Xu Haibo Zhou junxia zheng Pinghua Sun State Key Laboratory of Bioactive Molecules and Druggability Assessment College of PharmacyJinan UniversityGuangzhou 510632China Key Laboratory of Xinjiang Phytomedicine Resource and Utilization Ministry of EducationSchool of PharmacyShihezi UniversityShihezi 832003China School of Biomedical and Pharmaceutical Sciences Guangdong University of TechnologyGuangzhou 510006China Department of Oncology the First Affiliated Hospital of Jinan University GuangzhouGuangzhou 510632China Faculty of Medicine and Health the University of SydneySydney NSW 2006Australia

The management of antibiotic-resistant, bacterial biofilm infections in skin wounds poses an increasingly challenging clinical scenario. Pseudomonas aeruginosa infection is difficult to eradicate because of biofilm formation and antibiotic resistance. In this study, we identified a new benzothiazole derivative compound, SN12 (IC_(50)= 43.3 nmol/L), demonstrating remarkable biofilm inhibition at nanomolar concentrations in vitro. In further activity assays and mechanistic studies, we formulated an unconventional strategy for combating P. aeruginosa-derived infections by targeting the two-component (Gac/Rsm) system. Furthermore, SN12 slowed the development of ciprofloxacin and tobramycin resistance. By using murine skin wound infection models, we observed that SN12 significantly augmented the antibacterial effects of three widely used antibiotics—tobramycin (100-fold), vancomycin (200-fold), and ciprofloxacin (1000-fold)—compared with single-dose antibiotic treatments for P. aeruginosa infection in vivo. The findings of this study suggest the potential of SN12 as a promising antibacterial synergist, highlighting the effectiveness of targeting the two-component system in treating challenging bacterial biofilm infections in humans.

关键词： Pseudomonas aeruginosa Biofilm Antibioticresistant Two-component system Antibacterial synergist

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Treating incurable non-communicable diseases by targeting iron metabolism and ferroptosis

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Science China Life Sciences 2025年

作者： Ruoxuan Ni Jianwei Jiang Fudi Wang junxia Min The First Affiliated Hospital Institute of Translational Medicine Zhejiang University School of Medicine The Second Affiliated Hospital School of Public Health State Key Laboratory of Experimental Hematology Zhejiang University School of Medicine

Both iron metabolism and ferroptosis (an iron-dependent form of programmed cell death) have been connected to the development and progression of many currently incurable non-communicable diseases, including Alzheimer’s disease, Parkinson’s disease, multiple sclerosis,Huntington’s disease, metabolic dysfunction-associated steatohepatitis, heart failure, and both treatment-relapsed and refractory cancers,such as pancreatic ductal adenocarcinoma and triple-negative breast cancer. Thus, understanding the relationship between iron and these diseases can pave the way for the development of novel therapeutic strategies. Here, we summarize the latest evidence supporting the pathological roles of dysregulated iron metabolism and ferroptosis in a wide range of preclinical animal models of these currently incurable non-communicable diseases. We also summarize the feasibility of targeting iron metabolism and ferroptosis for the prevention and treatment of iron-and ferroptosis-related diseases that currently have limited treatment options. In addition, we provide our perspectives on the challenges and promises regarding the translational potential of targeting dysregulated iron metabolism and ferroptosis to treat diseases,highlighting the future roadmap for developing iron-and ferroptosis-targeted therapeutics.

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双语教学中运用翻转课堂教学模式的可行性分析

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山西科技 2015年第4期30卷 99-101页

作者：郑军霞青岛滨海学院山东青岛266555

双语教学是现在高校教学改革的一部分,目的是培养国际化的人才。但受到教学手段、师资和学生英语水平的影响,效果不尽如人意。翻转课堂是高度电子化时代的新的教学模式。介绍了双语教学中翻转课堂教学模式的运用,探讨了其可行性。

关键词：双语教学翻转课堂可行性分析

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阿奇霉素联合保妇康栓治疗非淋菌性宫颈炎的临床效果

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中国社区医师 2017年第18期33卷 90-90,92页

作者：郑军霞甘肃省平凉市中医医院 744000

目的:分析阿奇霉素联合保妇康栓治疗非淋菌性宫颈炎的效果。方法:收治非淋菌性宫颈炎患者100例,平分两组。单一组给予阿奇霉素,联合组给予阿奇霉素联合保妇康栓,比较并分析两组患者经治疗后的病原菌转阴比例与总有效率。结果:经治疗,联... 详细信息

目的:分析阿奇霉素联合保妇康栓治疗非淋菌性宫颈炎的效果。方法:收治非淋菌性宫颈炎患者100例,平分两组。单一组给予阿奇霉素,联合组给予阿奇霉素联合保妇康栓,比较并分析两组患者经治疗后的病原菌转阴比例与总有效率。结果:经治疗,联合组的病原菌转阴比例与总有效率都比单一组明显增加(P<0.05)。结论:应用阿奇霉素联合保妇康栓治疗非淋菌性宫颈炎的效果优异,能有效地杀病原菌,提高患者的生活质量。

关键词：阿奇霉素病原菌转阴保妇康栓非淋菌性宫颈炎

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提高无梭织机产质量的生产实践

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纺织导报 2005年第11期 43-46页

作者：李月英郑俊霞石家庄常山纺织股份有限公司

提高无梭织机的产质量是一项全面的系统工程,文章从生产实践角度论述了纺纱质量、织前准备、工艺优选、关键工艺部件、织机优选等5方面对无梭织机产质量的影响。并指出五大影响因素是宏观影响因素,在不同企业、不同时期影响程度不一。

关键词：无梭织机产量质量成纱质量影响因素

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Correlation between grain size,mechanical properties and deformed microstructure of Fe-20Mn-6Al-0.6C-0.15Si low-density steel

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Journal of Iron and Steel Research International 2025年第1期32卷 282-292页

作者： Qi Zhang Guang-hui Chen zheng-liang Xue zheng-kun Chen Guang Xu State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan430081HubeiChina Key Laboratory for Ferrous Metallurgy and Resources Utilization of Ministry of Education Wuhan University of Science and TechnologyWuhan430081HubeiChina Red Eagle Novel Refractory Materials Research Institute Zhejiang Red Eagle Group Co.Ltd.Huzhou313000ZhejiangChina

The effects of austenite grain size on the deformed microstructure and mechanical properties of an Fe-20Mn-6Al-0.6C-0.15Si(wt.%)low-density steel were *** microstructure of the experimental steel after solution treatment was single austenitic *** austenite grain size increased with solution temperature and time.A model was established to show the relationship between temperature,time and austenite grain size for the experimental *** addition,as the solution temperature increased,the strength decreased,while the elongation first increased and then *** decrease in elongation after solution treatment at 1100℃ for 90 min is contributed to the over-coarse austenite ***,after solution treatment at 900℃ for 90 min,the strength-elongation product reached the highest value of 44.4 GPa%.As the austenite grain size increased,the intensity of//tensile direction fiber *** was accompanied by a decrease in dislocation density,resulting in a lower fraction of low-angle grain boundaries and a lower work hardening ***,the austenite grain size has a critical influence on the mechanical properties of the low-density *** grains lead to a lower yield strength due to the Hall-Petch effect and a lower tensile strength because of lower dislocation strengthening.

关键词： Austenitic low-density steel Solution treatment Grain size Mechanical property Deformed microstructure

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An efficient conversion model between acceleration and pseudo-acceleration response spectra considering effects of magnitude,distance,and site class

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Earthquake Engineering and Engineering Vibration 2025年第1期24卷 15-30页

作者： Liu zheng Zhao Yan-Gang Zhang Haizhong Key Laboratory of Urban Security and Disaster Engineering of Ministry of Education Beijing University of TechnologyBeijing 100124China Faculty of Agriculture Yamagata University1-23Wakaba-machiTsuruoka-shiYamagata 997-8555Japan

Both acceleration and pseudo-acceleration response spectra play important roles in structural seismic ***,only one of them is generally provided in most seismic ***,many studies have attempted to develop conversion models between the acceleration response spectrum(SA)and the pseudo-acceleration response spectrum(PSA).Our previous studies found that the relationship between SA and PSA is affected by magnitude,distance,and site ***,we developed an SA/PSA model incorporating these ***,this model is suitable for cases with small and moderate magnitudes and its accuracy is not good enough for cases with large *** paper aims to develop an efficient SA/PSA model by considering influences of magnitude,distance,and site class,which can be applied to cases not only with small or moderate magnitudes but also with large *** this purpose,regression analyses were conducted using 16,660 horizontal seismic records with a wider range of *** magnitude of these seismic records varies from 4 to 9 and the distances vary from 10 to 200 *** ground motions were recorded at 338 stations covering four site *** comparing them with existing models,it was found that the proposed model shows better accuracy for cases with any magnitudes,distances,and site classes considered in this study.

关键词： acceleration response spectrum pseudo-acceleration response spectrum magnitude distance site class

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Luminescence: a new perspective for investigating perovskite precursors

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Science China Materials 2025年第1期68卷 312-313页

作者： Haofeng zheng Shaocong Hou School of Electrical Engineering and Automation Wuhan UniversityWuhan 430072China Wuhan University Shenzhen Research Institute Shenzhen 518057China

In the past two decades, perovskite materials have made significant progress in optoelectronic semiconductors, emerging as formidable candidates for the next generation of commercial solar cells, light-emitting diodes (LEDs), and *** the fundamental solution chemistry and photophysics in solution-processed perovskite devices is crucial for comprehending to achieve highly efficient optoelectronic devices.

关键词： optoelectronic diodes perovskite

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A Comprehensive Survey of Few-shot Information Networks

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Machine Intelligence Research 2025年第1期22卷 60-78页

作者： Xinxin zheng Feihu Che Jianhua Tao School of Artificial Intelligence University of Chinese Academy of SciencesBeijing100049China Institute of Automation Chinese Academy of SciencesBeijing100190China Department of Automation Tsinghua UniversityBeijing100084China

Information networks store rich information in the nodes and edges,which benefit many downstream tasks,such as recommender systems and knowledge graph *** networks contain homogeneous information,heterogeneous information and knowledge graphs.A significant number of surveys focus on one of the three parts and summarize the research works,but few surveys conclude and compare the three kinds of information *** addition,in real scenarios,lots of information networks lack sufficient labeled data,so the combination of meta-learning and information networks can bring in extended *** paper concentrates on few-shot information networks and systematically presents recent works to help analyze and follow related works.

关键词： Few-shot learning meta-learning homogeneous information networks heterogeneous information networks knowledge graphs

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