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Removal of nitrogen and phosphorus in a combined A^2/O-BAF system with a short aerobic SRT

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Journal of Environmental Sciences 2006年第6期18卷 1082-1087页

作者： DING Yong-wei wang Lin wang Bao-zhen wang zheng School of Municipal and Environmental Engineering Harbin Institute of Technology Harbin 150090 China School of Environmental Science and Engineering Ocean University of China Qingdao 266003 China

A bench-scale anaerobic/anoxic/aerobic process-biological aerated filter （A^2/O-BAF） combined system was carded out to treat wastewater with lower C/N and C/P ratios. The A^2/O process was operated in a short aerobic sludge retention time （SRT） for organic pollutants and phosphorus removal, and denitrification. The subsequent BAF process was mainly used for nitrification. The BAF effluent was partially returned to anoxic zone of the A^2/O process to provide electron acceptors for denitrification and anoxic P uptake. This unique system formed an environment for reproducing the denitdfying phosphate-accumulating organisms （DPAOs）. The ratio of DPAOs to phosphorus accumulating organisms （PAOs） could be maintained at 28% by optimizing the organic loads in the anaerobic zone and the nitrate loads into the anoxic zone in the A^2/O process. The aerobic phosphorus over-uptake and discharge of excess activated sludge was the main mechanism of phosphorus removal in the combined system. The aerobic SRT of the A^2/O process should meet the demands for the development of aerobic PAOs and the restraint on the nitrifiers growth, and the contact time in the aerobic zone of the A^2/O process should be longer than 30 min, which ensured efficient phosphorus removal in the combined system. The adequate BAF effluent return rates should be controlled with 1--4 mg/L nitrate nitrogen in the anoxic zone effluent of A^2/O process to achieve the optimal nitrogen and phosphorus removal efficiencies.

关键词： nitrogen and phosphorus removal denitrifying phosphorus removal denitrifying phosphorus accumulating organisms (DPAOs) anaerobic/anoxic/aerobic process (A^2/O) biological aerated filter (BAF) aerobic sludge retention time (SRT)

Soft-sensing modeling and intelligent optimal control strategy for distillation yield rate of atmospheric distillation oil refining process

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Chinese Journal of Chemical Engineering 2019年第5期27卷 1113-1124页

作者： zheng wang Cheng Shao Li Zhu Institute of Advanced Control Technology Dalian University of Technology

It is a challenge to conserve energy for the large-scale petrochemical enterprises due to complex production process and energy diversification. As critical energy consumption equipment of atmospheric distillation oil refining process, the atmospheric distillation column is paid more attention to save energy. In this paper, the optimal problem of energy utilization efficiency of the atmospheric distillation column is solved by defining a new energy efficiency indicator - the distillation yield rate of unit energy consumption from the perspective of material flow and energy flow, and a soft-sensing model for this new energy efficiency indicator with respect to the multiple working conditions and intelligent optimizing control strategy are suggested for both increasing distillation yield and decreasing energy consumption in oil refining process. It is found that the energy utilization efficiency level of the atmospheric distillation column depends closely on the typical working conditions of the oil refining process, which result by changing the outlet temperature, the overhead temperature, and the bottom liquid level of the atmospheric pressure tower. The fuzzy C-means algorithm is used to classify the typical operation conditions of atmospheric distillation in oil refining process. Furthermore, the LSSVM method optimized with the improved particle swarm optimization is used to model the distillation rate of unit energy consumption. Then online optimization of oil refining process is realized by optimizing the outlet temperature, the overhead temperature with IPSO again. Simulation comparative analyses are made by empirical data to verify the effectiveness of the proposed solution.

关键词： Energy efficiency optimization Crude oil distillation Particle warm optimization Fuzzy C-means algorithm Working condition

Dual Functions of Phospholipase Dα1 in Plant Response to Drought

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Molecular Plant 2008年第2期1卷 262-269页

作者： Yueyun Hong Suqin zheng Xuemin wang Department of Biology University of Missouri St Louis MO 63121 USADonald Danforth Plant Science Center St Louis MO 63132 USA

Phospholipase Dα1 （PLDα1） has been shown to mediate the abscisic acid regulation of stomatal movements. Arabidopsis plants deficient in PLDα1 increased, whereas PLDα1-overexpressing tobacco decreased, transpirational water loss. In the early stage of drought, the decrease in water loss was associated with a rapid stomatal closure caused by a high level of PLD in PLDα1-overexpressing plants. However, in the late stage of drought, the overexpressing plants displayed more susceptibility to drought than control plants. PLDα1 activity in the overexpressing plants was much higher than that of control plants in which drought also induced an increase in PLDα1 activity. The high level of PLDα1 activity was correlated to membrane degradation in late stages of drought, as demonstrated by ionic leakage and lipid peroxidation. These findings indicate that a high level of PLDα1 expression has different effects on plant response to water deficits. It promotes stomatal closure at earlier stages, but disrupts membranes in prolonged drought stress. These findings are discussed in relation to the understanding of PLD functions and potential applications.

关键词： drought phospholipase phosphatidic acid lipid oxidation lipid signaling.

Carbon-based materials for photodynamic therapy: A mini-review

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Frontiers of Chemical Science and Engineering 2019年第2期13卷 310-323页

作者： Di Lu Ran Tao zheng wang School of Pharmaceutical Science & Technology Tianjin Key Laboratory for Modem Drug Delivery & High EfficiencyCollaborative Innovation Center of Chemical Science and Engineering (Tianjin)Tianjin UniversityTianjin 300072China

Carbon-based materials have been extensively applied in photodynamic therapy owing to the unique optical characteristics,good biocompatibility and tunable systematic *** mini-review mainly focuses on the recent application of carbon-based materials including graphene,carbon nanotube,fullerene,corannulene,carbon dot and mesoporous carbon *** carbon-based materials can perform not only as photosensitizers,but also effective carriers for photosensitizers in photodynamic therapy,and its combined treatment.

关键词： photodynamic therapy carbon-based materials graphene carbon nanotube fullerene corannulene carbon dot mesoporous carbon nanoparticle

The second Hopf bifurcation in lid-driven square cavity

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Chinese Physics B 2020年第3期29卷 119-125页

作者： Tao wang Tiegang Liu zheng wang LIMB and School of Mathematical Science Beihang UniversityBeijing 100191China School of Mathematics and Information Science North Minzu UniversityYinchuan 750021China Wuhan Maritime Communication Research Institute Wuhan 430079China

To date, there are very few studies on the second Hopf bifurcation in a driven square cavity, although there are intensive investigations focused on the first Hopf bifurcation in literature, due to the difficulties of theoretical analyses and numerical simulations. In this paper, we study the characteristics of the second Hopf bifurcation in a driven square cavity by applying a consistent fourth-order compact finite difference scheme recently developed by us. We numerically identify the critical Reynolds number of the second Hopf bifurcation located in the interval of(11093.75, 11094.3604) by bisection. In addition, we find that there are two dominant frequencies in its spectral diagram when the flow is in the status of the second Hopf bifurcation, while only one dominant frequency is identified if the flow is in the first Hopf bifurcation via the Fourier analysis. More interestingly, the flow phase portrait of velocity components is found to make transition from a regular elliptical closed form for the first Hopf bifurcation to a non-elliptical closed form with self-intersection for the second Hopf bifurcation. Such characteristics disclose flow in a quasi-periodic state when the second Hopf bifurcation occurs.

关键词： unsteady lid-driven cavity flows second Hopf bifurcation critical Reynolds number numerical simulation

Genomics progress will facilitate molecular breeding in soybean

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Science China(Life Sciences) 2015年第8期58卷 813-815页

作者： wang zheng TIAN ZhiXi State Key Laboratory of Plant Cell and Chromosome Engineering Institute of Genetics and Developmental Biology Chinese Academy of Sciences

It has been suggested that the soybean （Glycine max [L.] Merr.） currently cultivated in commercial agriculture was domesticated from the wild soybean （G. soja Sieb. ＆ Zucc.） in China approximately 5,000 years ago. Because of its high protein and oil content, cultivated soybean has become a major economic crop by providing 69% and 30% of the world＇s plant protein and oil. Soybean breeders have made considerable efforts to develop elite varieties that can meet this ever-increasing demand. However, over the last century, advances in soybean breeding have progressed slowly. One of the major reasons is the genetic bottlenecks caused by the domestication practice of using seeds from only a small number of plants with desirable traits to propagate each new generation during introduction and im- provement [1]. Well-established genome sequences and a better understanding of the underlying genetic bases of agronomically important traits will expedite the progress of marker-assisted breeding programs for soybean.

关键词：野生大豆基因组学分子育种植物蛋白遗传基础农艺性状基因组序列栽培驯化

Propagation History Ranking in Social Networks:A Causality-Based Approach

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Tsinghua Science and Technology 2020年第2期25卷 161-179页

作者： zheng wang Chaokun wang Xiaojun Ye Jisheng Pei Bin Li Department of Computer Science and Technology University of Science and Technology BeijingChina School of Software Tsinghua UniversityBeijing 100084China China Information Technology Security Evaluation Center Beijing 100085China

Information diffusion is one of the most important issues in social network *** most existing works,which either rely on network topology or node profiles,this study focuses on the diffusion itself,i.e.,the recorded propagation *** histories are the evidence of diffusion and can be used to explain to users what happened in their ***,these histories can quickly grow in size and complexity,limiting their capacity to be intuitively *** reduce this information overload,in this paper we present the problem of propagation history *** goal is to rank participant edges/nodes by their contribution to the *** first discuss and adapt a causal measure,Difference of Causal Effects(DCE),as the ranking ***,to avoid the complex calculation of DCE,we propose two integrated ranking strategies by adopting two *** is responsibility,which captures the necessity aspect of causal *** further give an approximate algorithm,which could guarantee a feasible solution,for this *** other is capability,which captures the sufficiency aspect of causal ***,promising experimental results are presented to verify the feasibility of the proposed ranking strategies.

关键词： propagation history ranking causality social networks information diffusion

Achieving tunable long persistent luminescence in metal organic halides based on pyridine solvent

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Chinese Chemical Letters 2024年第9期35卷 227-231页

作者： Jun-Ting Mo zheng wang College of Chemistry and Chemical Engineering Key Laboratory of Chemical Additives for China National Light IndustryShaanxi University of Science and TechnologyXi’an 710021China MOE Laboratory of Bioinorganic and Synthetic Chemistry Lehn Institute of Functional MaterialsSchool of ChemistrySun Yat-sen UniversityGuangzhou 510275China

The research of long persistent luminescence(LPL)materials has yield brilliant results in many ***,the efforts are still needed for the regulation of the LPL *** this work,a series of LPL metal organic halides with rich halogen-bond interactions,Py-CdX_(2)(X=Cl,Br,I)were synthesized through self-assembly by Cd X_(2)and pyridine *** steady-state emission redshifted and phosphorescence lifetime declined as the halogen atoms are *** halides exhibit adjustable emission from blue to green and multiple phosphorescence from green to yellow at room temperature by changing the excitation ***,Py-CdX_(2)can emit the visible color-tunable LPL from green to yellow after removing different excitation sources at ambient *** the results of theoretical calculation and experimental analysis,it is found that heavy atom effect and the rich intermolecular halogen bond help realize LPL and multiple triplet states originated from the pyridine ring and the halogens.

关键词： Metal organic halide Heavy atom effect Halogen bond Tunable long persistent luminescence Anti-counterfeiting

基于PERK-eIF2α-NF-κB信号通路研究苁蓉散治疗阿尔茨海默病的作用机制

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中国药理学通报 2025年第1期41卷 80-87页

作者：王曦龙清华蔡元钦王政喻陈显兵曾楚华湖北民族大学医学部湖北恩施445000 湖北民族大学风湿性疾病发生与干预湖北省重点实验室湖北恩施445000 云南中医药大学基础医学院云南昆明650000

目的基于PERK-eIF2α-NF-κB信号通路研究苁蓉散治疗阿尔茨海默病(Alzheimer’s disease,AD)的作用机制。方法将60只SD大鼠分为正常组,模型组、苁蓉散组(4.62、9.24、18.48 g·kg-1)和安理申组,每组10只。除正常组外其余大鼠组予双侧海... 详细信息

目的基于PERK-eIF2α-NF-κB信号通路研究苁蓉散治疗阿尔茨海默病(Alzheimer’s disease,AD)的作用机制。方法将60只SD大鼠分为正常组,模型组、苁蓉散组(4.62、9.24、18.48 g·kg-1)和安理申组,每组10只。除正常组外其余大鼠组予双侧海马注射Aβ1-42建立AD模型。灌胃结束后进行水迷宫行为学检测学习记忆能力;尼氏染色观察神经元及尼氏小体变化;免疫荧光检测NF-κB核转移情况;透射电镜观察大鼠海马区内质网形态;酶免疫测定Aβ1-42及炎症因子含量;Western blot检测PERK、eIF2α、NF-κB的蛋白表达水平。结果水迷宫结果显示,苁蓉散能提高AD大鼠的逃避潜伏期时间、增加穿越求生平台次数、延长目标象限停留时间(P<0.05或P<0.01);尼氏染色结果显示,苁蓉散各剂量组神经元细胞排列较整齐,胞核存在,尼氏小体较为丰富;免疫荧光表明,苁蓉散可降低AD大鼠脑内NF-κB入核表达(P<0.05或P<0.01);透射电镜结果显示,苁蓉散各剂量组内质网形态整齐、未见明显扩张,结构正常;ELISA结果表明,苁蓉散可降低AD海马中的Aβ1-42,IL-1,TNF-α的含量;Western blot结果显示,苁蓉散各剂量组p-PERK/PERK,p-eIF2α/eIF2α,p-NF-κB p65/NF-κB p65的蛋白比值明显下降(P<0.05或P<0.01)。结论苁蓉散可通过抑制PERK-eIF2α-NF-κB信号通路的活化,缓解神经元细胞ERS状态下免疫炎症反应,以改善AD大鼠的认知功能。

关键词：阿尔兹海默病苁蓉散内质网应激 PERK-eIF2α-NF-κB信号通路炎症 Aβ1-42