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Dynamic Regulation of Hydrogen Bonding Networks and Solvation Structures for Synergistic Solar‑Thermal Desalination of Seawater and Catalytic Degradation of Organic Pollutants

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Nano-Micro Letters 2025年第2期17卷 548-565页

作者： Ming‑yuan Yu Jing Wu Guang Yin Fan‑zhen Jiao Zhong‑zhen Yu Jin Qu Beijing Key Laboratory of Advanced Functional Polymer Composites Beijing University of Chemical TechnologyBeijing 100029People’s Republic of China State Key Laboratory of Organic‑Inorganic Composites College of Materials Science and EngineeringBeijing University of Chemical TechnologyBeijing 100029People’s Republic of China

Although solar steam generation strategy is efficient in desalinating seawater,it is still challenging to achieve continuous solar-thermal desalination of seawater and catalytic degradation of organic ***,dynamic regulations of hydrogen bonding networks and solvation structures are realized by designing an asymmetric bilayer membrane consisting of a bacterial cellulose/carbon nanotube/Co_(2)(OH)_(2)CO_(3)nanorod top layer and a bacterial cellulose/Co_(2)(OH)_(2)CO_(3)nanorod(BCH)bottom ***,the hydrogen bonding networks inside the membrane can be tuned by the rich surface–OH groups of the bacterial cellulose and Co_(2)(OH)_(2)CO_(3)as well as the ions and radicals in situ generated during the catalysis ***,both SO_(4)^(2−)and HSO_(5)−can regulate the solvation structure of Na^(+)and be adsorbed more preferentially on the evaporation surface than Cl^(−),thus hindering the de-solvation of the solvated Na^(+)and subsequent nucleation/growth of ***,the heat generated by the solar-thermal energy conversion can accelerate the reaction kinetics and enhance the catalytic degradation *** work provides a flow-bed water purification system with an asymmetric solar-thermal and catalytic membrane for synergistic solar thermal desalination of seawater/brine and catalytic degradation of organic pollutants.

关键词： Solar steam generation Seawater desalination Catalytic degradation Bacterial cellulose Cobalt hydroxycarbonate nanorods

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Boundary-Based Time Series Sorting

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Journal of Electronic Science and Technology of China 2008年第3期6卷 323-328页

作者： Jun-Kui Li yuan-zhen wang Hai-Bo Li College of Computer Science and Technology Huazhong University of Science and Technology Wuhan 430074 China

In many applications, it is desirable to sort the data. Most of previous work on sorting are key based, however, there are no apparent keys for the time-series data and therefore the classic sorting algorithms may fail in sorting time-series data. We propose a novel technique, called TS-Sort, to sort time-series sequences in the massive set. The proposed method first extracts the maximum and minimum boundaries of the set, then calculates the distance values between the sequences to the boundaries, and finally sorts the values to determine the relative orders of sequences in the set. For improvement, we propose a partition based version of the algorithm, which puts the sequences into small groups, and sorts the groups to get the final sorted set. Extensive experiments, both on synthetic and real datasets, show that our approach can be used to make the time series set in order, and there is a factor of up to 26.3% accelerating for the improved version of the method.

关键词： Boundary comparison sorting time series

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Combined ATAC-seq,RNA-seq,and GWAS analysis reveals glycogen metabolism regulatory network in Jinjiang oyster(Crassostrea ariakensis)

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Zoological Research 2024年第1期45卷 201-214页

作者： Biao Wu Xi Chen Jie Hu zhen-yuan wang Yan wang Da-You Xu Hao-Bing Guo Chang-Wei Shao Li-Qing Zhou Xiu-Jun Sun Tao Yu Xiao-Mei wang Yan-Xin zheng Guang-Yi Fan Zhi-Hong Liu State Key Laboratory of Mariculture Biobreeding and Sustainable Goods Yellow Sea Fisheries Research InstituteChinese Academy of Fishery SciencesQingdaoShandong 266071China Laboratory for Marine Fisheries Science and Food Production Processes Laoshan LaboratoryQingdaoShandong 266071China BGI-Qingdao BGI-ShenzhenQingdaoShandong 266426China National Demonstration Center for Experimental Fisheries Science Education Shanghai Ocean UniversityShanghai 201306China Changdao Enhancement and Experiment Station Chinese Academy of Fishery SciencesYantaiShandong 265800China State Key Laboratory of Agricultural Genomics BGI-ShenzhenShenzhenGuangdong 518083China

Glycogen serves as the principal energy reserve for metabolic processes in aquatic shellfish and substantially contributes to the flavor and quality of *** Jinjiang oyster(Crassostrea ariakensis)is an economically and ecologically important species in *** the present study,RNA sequencing(RNA-seq)and assay for transposase-accessible chromatin using sequencing(ATAC-seq)were performed to investigate gene expression and chromatin accessibility variations in oysters with different glycogen *** identified 9483 differentially expressed genes(DEGs)and 7215 genes with significantly differential chromatin accessibility(DCAGs)were obtained,with an overlap of 2600 genes between ***,a significant proportion of these genes were enriched in pathways related to glycogen metabolism,including“Glycogen metabolic process”and“Starch and sucrose metabolism”.In addition,genome-wide association study(GWAS)identified 526 single nucleotide polymorphism(SNP)loci associated with glycogen *** loci corresponded to 241 genes,63 of which were categorized as both DEGs and *** study enriches basic research data and provides insights into the molecular mechanisms underlying the regulation of glycogen metabolism in ***.

关键词： Crassostrea ariakensis Glycogen Transcriptome ATAC GWAS

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A Grammar Analysis Model for the Unified Multimedia Query Language

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Journal of Electronic Science and Technology of China 2008年第3期6卷 317-322页

作者： Zhong-Sheng Cao Zong-Da Wu yuan-zhen wang School of Computer Science and Technology Huazhong University of Science and Technology Wuhan 430074 China

The unified multimedia query language （UMQL） is a powerful general-purpose multimedia query language, and it is very suitable for multimedia information retrieval. The paper proposes a grammar analysis model to implement an effective grammatical processing for the language. It separates the grammar analysis ofa UMQL query specification into two phases： syntactic analysis and semantic analysis, and then respectively uses Backus-Naur form （EBNF） and logical algebra to specify both restrictive grammar rules. As a result, the model can present error guiding information for a query specification which owns incorrect grammar. The model not only suits well the processing of UMQL queries, but aLso has a guiding significance for other projects concerning query processings of descriptive query languages.

关键词： Grammar analysis query language query processing unified multimedia query language

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A promising approach for quantifying focal stroke modeling and assessing stroke progression:optical resolution photoacoustic microscopy photothrombosis

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Neural Regeneration Research 2025年第7期20卷 2029-2037页

作者： Xiao Liang Xingping Quan Xiaorui Geng Yujing Huang Yonghua Zhao Lei Xi zhen yuan Ping wang Bin Liu Faculty of Health Sciences University of MacaoMacao Special Administrative RegionChina Center for Cognitive and Brain Sciences University of MacaoMacao Special Administrative RegionChina Department of Biomedical Engineering Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoTaipaMacao Special Administrative RegionChina Department of Emergency Zhujiang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina

To investigate the mechanisms underlying the onset and progression of ischemic stroke,some methods have been proposed that can simultaneously monitor and create embolisms in the animal cerebral ***,these methods often require complex systems and the effect of age on cerebral embolism has not been adequately studied,although ischemic stroke is strongly *** this study,we propose an optical-resolution photoacoustic microscopy-based visualized photothrombosis methodology to create and monitor ischemic stroke in mice simultaneously using a 532 nm pulsed *** observed the molding process in mice of different ages and presented age-dependent vascular embolism ***,we integrated optical coherence tomography angiography to investigate age-associated trends in cerebrovascular variability following a *** imaging data and quantitative analyses underscore the differential cerebrovascular responses to stroke in mice of different ages,thereby highlighting the technique's potential for evaluating cerebrovascular health and unraveling age-related mechanisms involved in ischemic strokes.

关键词： age-dependent cerebral cortex ischemic stroke mouse model optical coherence tomography angiography photoacoustic microscopy photothrombosis vascular imaging

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Wafer‑Scale Ag_(2)S‑Based Memristive Crossbar Arrays with Ultra‑Low Switching‑Energies Reaching Biological Synapses

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Nano-Micro Letters 2025年第3期17卷 328-339页

作者： yuan Zhu Tomas Nyberg Leif Nyholm Daniel Primetzhofer Xun Shi zhen Zhang Division of Solid‑State Electronics Department of Electrical EngineeringUppsala University75121 UppsalaSweden Department of Chemistry Uppsala UniversityUppsalaSweden Department of Physics and Astronomy Uppsala UniversityUppsalaSweden State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050People’s Republic of China

Memristive crossbar arrays(MCAs)offer parallel data storage and processing for energy-efficient neuromorphic ***,most wafer-scale MCAs that are compatible with complementary metal-oxide-semiconductor(CMOS)technology still suffer from substantially larger energy consumption than biological synapses,due to the slow kinetics of forming conductive paths inside the memristive *** we report wafer-scale Ag_(2)S-based MCAs realized using CMOS-compatible processes at temperatures below 160℃.Ag_(2)S electrolytes supply highly mobile Ag+ions,and provide the Ag/Ag_(2)S interface with low silver nucleation barrier to form silver filaments at low energy *** further enhancing Ag+migration in Ag_(2)S electrolytes via microstructure modulation,the integrated memristors exhibit a record low threshold of approximately−0.1 V,and demonstrate ultra-low switching-energies reaching femtojoule values as observed in biological *** low-temperature process also enables MCA integration on polyimide substrates for applications in flexible ***,the intrinsic nonidealities of the memristive units for deep learning can be compensated by employing an advanced training *** impressive accuracy of 92.6%in image recognition simulations is demonstrated with the MCAs after the *** demonstrated MCAs provide a promising device option for neuromorphic computing with ultra-high energy-efficiency.

关键词： Wafer-scale Ag_(2)S films Reactive sputter Silver nucleation Ag^(+)migration Energy-efficient neuromorphic computing

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Distributions of HLA-A and-B alleles and haplotypes in the Yi ethnic minority of Yunnan, China: relationship to other populations

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2010年第2期11卷 127-135页

作者： Bo-feng ZHU Guang YANG Chun-mei SHEN Hai-xia QIN Shun-zhi LIU Ya-jun DENG Shuan-liang FAN Li-bin DENG Feng CHEN Ping ZHANG Jie FANG Li-ping CHEN Hong-dan wang zhen-yuan wang Rudolf LUCAS Department of Forensic Medicine School of Medicine Xi 'an Jiaotong University Xi 'an 710061 China Key Laboratory of Environment and Genes Related to Diseases of Ministry of Education Xi'an Jiaotong University Xi 'an 710061 China Vascular Biology Center Medical College of Georgia Augusta Georgia 30912 USA Shaan'xi Blood Center Xi 'an 710061 China Institute of Molecular Medicine and Genetics Medical College of Georgia Augusta Georgia 30912 USA Department of Public Health School of Medicine Xi'an Jiaotong University Xi'an 710061 China Center of Forensic Sciences Beijing Genomics Institute Beijing 101300 China Faculty of Basic Medical Science Nanchang University Nanchang 330006 China

Objective: To investigate the distributions of human leukocyte antigen (HLA)-A and-B alleles and HLA-A-B haplotypes in the Yi ethnic minority of the Yunnan Province, situated in southwestern China. Methods: DNA typing for HLA-A and-B loci was performed using the polymerase chain reaction-sequence-based typing (PCR-SBT) method on 114 randomly selected healthy individuals of the Yi population. The allelic frequencies of HLA-A and-B loci were calculated by direct counting and HLA-A-B haplotypes were estimated using the expectation maximization algorithm. Results: A total of 17 HLA-A and 38 HLA-B alleles were found in the Yi population. The most frequent alleles were A2402 (32.46%), A1101 (26.32%), and A0203 (10.09%) at the HLA-A locus and B4601 (12.28%), B1525 (10.09%), B4001 (8.77%), and B3802 (7.89%) at the HLA-B locus. The predominant HLA-A-B haplotypes were A2402-B1525 (7.86%) and A0203-B3802 (5.64%), followed by A1101-B4001 (4.69%). Phylogenetic analysis indicates that the Yi population in the Honghe, Yunnan Province of China basically belongs to groups of southeastern Asian origin, but shares some characteristics with northeastern Asian groups. Conclusion: The present study may add to the understanding of HLA polymorphism in the Yi ethnic group that was poorly defined previously, and provide useful information for bone marrow transplantation, anthropological research, and forensic sciences as well as for disease-association studies.

关键词： Yi ethnic minority Human leukocyte antigen (HLA)-A HLA-B Allele Haplotype Polymerase chain reaction-sequence-based typing (PCR-SBT)

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Prognostic factors and staging systems of multiple myeloma:a single centre study in China

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Chinese Medical Journal 2007年第19期120卷 1655-1658页

作者： TAO Zhong-fei FU Wei-jun yuan zhen-gang wang Dong-xing CHEN Yu-bao HOU Jian Department of Haematology Shanghai Changzheng Hospital Second Military Medical University Shanghai 200003 China

Background Previous studies found a range of prognostic factors but no consensus about the proper staging system for multiple myeloma has been achieved. This study explored the prognostic factors to find a staging system for multiple myeloma most suitable for Chinese patients. Methods Between February 1990 to August 2004, 206 patients （138 men and 68 women, mean aged （59±11） years） who were initially diagnosed as multiple myeloma in Changzheng Hospital （Shanghai, China） and had followup records were enrolled in this study. Potential prognostic factors were evaluated by univariate and multivariate analyses. Four staging systems were applied to compare their suitability for the patients. Results The median survival time of the patients was 33 months. The 1-, 3- and 5-year survival rates were 80.18%, 48.08% and 33.7% respectively. Factors identified as adversely affecting survival were older age, severe bone lesions, low haemoglobin, low platelet, low serum calcium, low serum albumin, high proportion of plasma cells in marrow, high serum creatinine, high serum β2 microglobulin and high C-reactive protein. Among these, only C-reactive protein, β2 microglobulin, albumin and age were the independent prognostic factors. There were statistically significant survival differences among the three groups in Durie Salmon staging system and Bataille staging system, but not in British Medical Research Council staging system or International Staging System. Conclusions High β2 microglobulin, high C-reactive protein, low albumin and old age are independent prognostic factors of multiple myeloma. Bataille staging system appears to be optimal for Chinese multiple myeloma patients.

关键词： multiple myeloma prognosis survival analysis clinical staging system

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Report of 16 kindreds and one kindred with hMLH1 germline mutation

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World Journal of Gastroenterology 2002年第2期8卷 263-264页

作者： Bo Zhao zhen-Jun wang yuan-Lian Wan Peng Li Yan-Ting Huang,Department of Surgery,Peking University First Hospital,Beijing 1000.34,China Yu-Feng Xu,Experimental Center,Peking University First Hospital,Beijing 100034,China Department of Surgery Peking University First Hospital No. 8 Xishiku Street Western Distract Beijing 100034 China.

AIM: To analyze the diagnosis and treatment of 16 hereditarynonpolyposis colorectal cancer (HNPCC) kindreds, and toreport the first kindred with hMLH1 germline mutation inChina's ***: The diagnosis, treatment and follow-up study of16 HNPCC kindreds were retrospectively reviewed. Dataconceming site of the malignant tumor, age st the diagnosis,history of synchronous and/ or metachronous cancer, andhistopathology of tumors were recorded. All treatments hadwon formal consent. PCR and SSCP were used to screen thecoding region of hMLH1 and hMSH2 genes. Variant bandswere sequenced by a 377 DNA ***: Among sixteen kindreds, sixty-eight patients hada mean age of 50.8 years, including twenty-one multiplecancer patients and forty-six colorectal cancer patients(metachronous colorectal cancers in sixteen). A total of onehundred and one malignant neoplasms were found in thesesixty-eight patients, including 50 colonic, 17 rectal, 11gastric, 7 endometrial, and 4 esophageal cancers. 39.5%colorectal patients had metachronous cancers within tenyears who needed reopeertions. A germline G265T nonsensemutation was found in the third exon of hMLH1, resulting in astop codon and truncated protein. Three phenotypically normalfamily members were also found to carry the mutated ***: HNPCC is a typical auto-dominant hereditaryisease, the main characteristics include early onset andfrequency of cancers; predominance of colorectal,especially right-sided colon cancers; frequency of multipleprimary cancers (especially colorectal cancers). Segmentalresection for colorectal cancers is not eligible for colorectalcancer patient in HNPCC kindreds. Intensive follow-up isessential for all patients and possible gene carriers. The firstHNPCC kindred with hMUH1 gene germline mutation wasidentified in China's Mainland, and three phenotypicallynormal family members were found to be carriers of themutated gene. The G265T germline (nonsense) mutation inthe third exon of hMLH1

关键词：亲缘族 hMLH1 种类突变结直肠癌

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苹果树腐烂病菌活性物质的提取分离及结构鉴定

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西北农业学报 2017年第6期26卷 946-949页

作者：甄伟袁艮霞王惠黄丽丽西北农林科技大学理学院陕西杨凌712100 西北农林科技大学旱区作物逆境生物学国家重点实验室陕西杨凌712100 西北农林科技大学植物保护学院陕西杨凌712100

为探索苹果树腐烂病菌(Valsa mali)野生型菌株03-8产生的活性物质及其与致病性的关系,在以蔗糖为碳源的MS液体培养基中25℃静置培养20d,利用大孔树脂吸附、二氯甲烷萃取、薄层层析和高效液相色谱等手段分离纯化,~1H-NMR、^(13)C-NMR、DE... 详细信息

为探索苹果树腐烂病菌(Valsa mali)野生型菌株03-8产生的活性物质及其与致病性的关系,在以蔗糖为碳源的MS液体培养基中25℃静置培养20d,利用大孔树脂吸附、二氯甲烷萃取、薄层层析和高效液相色谱等手段分离纯化,~1H-NMR、^(13)C-NMR、DEPT135、HMQC谱对纯化合物进行结构鉴定,并测定其生物活性。最终分离得到一个化合物D-2;结构鉴定为1-(3′-乙烯基-苯基)-1,2-乙二醇;该化合物1mg/mL的丙酮水[V(丙酮)∶V(水)=1∶4]溶液不能在烟草和苹果叶片上引起坏死斑,但对枯草芽孢杆菌有抑制作用。

关键词：苹果树腐烂病菌提取分离鉴定抑菌活性

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