检索结果-南通市图书馆

Prospective Cohort Investigation on Physical Activity of Osteoporosis Outcomes(PAOPO)in Jidong:Objectives,Study Design,and Baseline Characteristics

在线全文

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2024年第9期37卷 1067-1079页

作者： Jingzhi Yang Hao shen Sicheng Wang Long Bai zhen Geng Yingying Jing Ke Xu Yuhe Liu Wenqian Wu Hao Zhang Yuanwei Zhang Zuhao Li Chuandong Wang Guangchao Wang Xiao Chen Jiacan su Institute of Translational Medicine Shanghai UniversityShanghai 200444China Orthopedic Department of Xinhua Hospital affiliated to Shanghai Jiaotong University School of Medicine Shanghai 200092China Department of Orthopedics Trauma Shanghai Zhongye HospitalShanghai 200941China Clinical Research Institute Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China

Objective The aim of this study was to investigate the prospective association between physical activity(PA),independently or in conjunction with other contributing factors,and osteoporosis(OP)*** The Physical Activity in Osteoporosis Outcomes(PAOPO)study was a community-based cohort investigation.A structured questionnaire was used to gather the participants’sociodemographic *** mineral density(BMD)measurements were performed to assess OP outcomes,and the relationship between BMD and OP was evaluated within this *** From 2013 to 2014,8,471 participants aged 18 years and older were recruited from Tangshan,China’s Jidong *** on their PA level,participants were categorized as inactive,moderately active,or very *** showed higher physical exercise levels than women across the activity *** was significantly higher in the very active group than in the moderately active and inactive *** aged>50 years are at a higher risk of developing OP and *** The PAOPO study offers promising insights into the relationship between PA and OP outcomes,encouraging the implementation of PA in preventing and managing OP.

关键词： Osteoporosis Physical activity Risk factors Cohort study

在线全文

学校读者我要写书评

暂无评论

基于聚焦激波的微结构非接触式激励方法研究

传感器与微系统 2024年第4期43卷 41-44页

作者：佘东生于震田江平渤海大学控制科学与工程学院辽宁锦州121013 大连理工大学能源与动力学院辽宁大连116024

为了解决MEMS微结构非接触式激励的问题,提出了一种基于聚焦激波的非接触式激励方法。该方法的基本原理是利用高压电容空气放电来产生激波,再通过半椭球腔体对激波进行聚焦,从而实现对微结构的非接触式激励。基于该方法搭建了微结构动... 详细信息

为了解决MEMS微结构非接触式激励的问题,提出了一种基于聚焦激波的非接触式激励方法。该方法的基本原理是利用高压电容空气放电来产生激波,再通过半椭球腔体对激波进行聚焦,从而实现对微结构的非接触式激励。基于该方法搭建了微结构动态特性测试系统,并对矩形等截面和T型单晶硅微悬臂梁的动态特性进行了测试实验,获得了两种微悬臂梁的一阶有阻尼固有频率和阻尼比。实验结果表明:矩形等截面和T型单晶硅微悬臂梁一阶无阻尼固有频率分别为5 912 Hz和2 150 Hz。通过动态测试实验验证了基于聚焦激波非接触式激励方法在MEMS微结构激励上的有效性。

关键词：聚焦激波 MEMS微结构非接触式激励动态特性测试

维普期刊数据库博看期刊

Advancements of Macrophages Involvement in Pathological Progression of Colitis-Associated Colorectal Cancer and Associated Pharmacological Interventions

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Integrative Medicine 2024年第6期30卷 565-576页

作者： KE Jun-yu SONG Jin-bin LI Long HE zhen-fan HUANG Zhuo-jian LIU zheng-lin CHEN Gui-rong WANG Hai-yan WEN su-ru ZHOU Heng-li MA Hui-lin DU Qun WU Yong-qiang LI Yan-wu CHEN Xin-lin School of Basic Medical Sciences Guangzhou University of Chinese MedicineGuangzhou510006China Department of surgery II Gaozhou Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese MedicineGaozhou525200China Science and Technology Innovation Center Guangzhou University of Chinese MedicineGuangzhou510405China The First Clinical Medical College of Guangzhou University of Traditional Chinese Medicine Guangzhou510405China

Intestinal macrophages play crucial roles in both intestinal inflammation and immune homeostasis. They can adopt two distinct phenotypes, primarily determined by environmental cues. These phenotypes encompass the classically activated pro-inflammatory M1 phenotype, as well as the alternatively activated anti-inflammatory M2 phenotype. In regular conditions, intestinal macrophages serve to shield the gut from inflammatory harm. However, when a combination of genetic and environmental elements influences the polarization of these macrophages, it can result in an M1/M2 macrophage activation imbalance, subsequently leading to a loss of control over intestinal inflammation. This shift transforms normal inflammatory responses into pathological damage within the intestines. In patients with ulcerative colitis-associated colorectal cancer (UC-CRC), disorders related to intestinal inflammation are closely correlated with an imbalance in the polarization of intestinal M1/M2 macrophages. Therefore, reinstating the equilibrium in M1/M2 macrophage polarization could potentially serve as an effective approach to the prevention and treatment of UC-CRC. This paper aims to scrutinize the clinical evidence regarding Chinese medicine (CM) in the treatment of UC-CRC, the pivotal role of macrophage polarization in UC-CRC pathogenesis, and the potential mechanisms through which CM regulates macrophage polarization to address UC-CRC. Our objective is to offer fresh perspectives for clinical application, fundamental research, and pharmaceutical advancement in UC-CRC.

关键词： macrophage ulcerative colitis colon cancer Chinese medicine

Effect of Chinese Medicine in Patients with COVID-19: A Multi-center Retrospective Cohort Study

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Integrative Medicine 2024年第11期30卷 974-983页

作者： ZHAO Guo-zhen YAN Shi-yan LI Bo GUO Yu-hong SONG Shuang HU Ya-hui GUO Shi-qi HU Jing DU Yuan LU Hai-tian YE Hao-ran REN Zhi-ying ZHU Ling-fei XU Xiao-long su Rui LIU Qing-quan Beijing Hospital of Traditional Chinese Medicine Capital Medical University Beijing Institute of Traditional Chinese Medicine School of Clinical Medicine Beijing University of Chinese Medicine School of Acupuncture-Moxibustion and Tuina Beijing University of Chinese Medicine College of Integrated Chinese Medicine Tianjin University of Traditional Chinese Medicine

Objective: To evaluate the effectiveness and safety of Chinese medicine(CM) in the treatment of coronavirus disease 2019(COVID-19) in China. Methods: A multi-center retrospective cohort study was carried out, with cumulative CM treatment period of 3 days during hospitalization as exposure. Data came from consecutive inpatients from December 19, 2019 to May 16, 2020 in 4 medical centers in Wuhan, China. After data extraction, verification and cleaning, confounding factors were adjusted by inverse probability of treatment weighting(IPTW), and the Cox proportional hazards regression model was used for statistical analysis. Results:A total of 2,272 COVID-19 patients were included. There were 1,684 patients in the CM group and 588 patients in the control group. Compared with the control group, the hazard ratio(HR) for the deterioration rate in the CM group was 0.52 [95% confidence interval(CI): 0.41 to 0.64, Psults were consistent across patients of varying severity at admission, and the robustness of the results were confirmed by 3 sensitivity analyses. In addition, the HR for all-cause mortality in the CM group was 0.29(95% CI: 0.19 to 0.44, Psult can provide the new evidence to support the current treatment of COVID-19. Additional prospective clinical trial is needed to evaluate the efficacy and safety of specific CM interventions.(Registration No. ChiCTR2200062917)

关键词： Chinese medicine all-cause mortality cohort study coronavirus disease 2019 deterioration rate

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

铝合金在接触固溶处理工艺中的界面传热系数

Transactions of Nonferrous Metals Society of China 2024年第2期34卷 453-464页

作者：苏雪荣宋振坤张志强吉林大学材料科学与工程学院长春130022

采用有限元模拟和反演优化(IO)方法测定7075铝合金在不同压力、表面粗糙度和温度下接触固溶处理过程中的界面传热系数(IHTC)值,并分析这些因素对IHTC的影响。结果表明:随着压力的增加,IHTC值先增加,然后保持稳定;IHTC值随表面粗糙度的... 详细信息

采用有限元模拟和反演优化(IO)方法测定7075铝合金在不同压力、表面粗糙度和温度下接触固溶处理过程中的界面传热系数(IHTC)值,并分析这些因素对IHTC的影响。结果表明:随着压力的增加,IHTC值先增加,然后保持稳定;IHTC值随表面粗糙度的增大而减小;随着板温的升高,瞬时IHTC值先增大后减小。基于压力、表面粗糙度和温度的综合影响规律,建立多因素影响的IHTC理论模型。使用此模型能较好地预测不同条件下合金的瞬时IHTC值。

关键词：铝合金接触固溶处理界面传热系数有限元分析反演优化

土壤盐分变化对N_(2)O排放影响:基于Meta分析

在线全文

学校读者我要写书评

暂无评论

环境科学 2024年第4期45卷 2313-2320页

作者：黄艺华佘冬立史祯琦胡磊潘永春河海大学农业科学与工程学院南京210098 江苏省农业水土资源高效利用与固碳减排工程研究中心南京210098

N_(2)O是导致臭氧层空洞和全球变暖的主要大气污染物,农业生产活动是其主要来源,而土壤盐分则是影响N_(2)O排放的关键因素.基于21篇同行评议文献中528对实验组及对照组形成的数据集,运用R语言Metafor软件包进行Meta分析,进而评估土壤盐... 详细信息

N_(2)O是导致臭氧层空洞和全球变暖的主要大气污染物,农业生产活动是其主要来源,而土壤盐分则是影响N_(2)O排放的关键因素.基于21篇同行评议文献中528对实验组及对照组形成的数据集,运用R语言Metafor软件包进行Meta分析,进而评估土壤盐分对土壤N_(2)O排放的影响.结果表明,土壤盐分累积对N_(2)O排放量有显著正效应,中度和高度盐渍土N_(2)O排放量比非盐渍土高75.57%和28.85%.室内培养实验测定结果表明,林地和农田的土壤盐渍化导致N_(2)O排放量增加124.79%和131.64%,而野外定位监测试验结果表明,草地、裸地和农田中,土壤盐分对N_(2)O排放的影响均不显著.盐分对N_(2)O排放的影响趋势则因土壤(NH_(4)^(+)∶NO_(3)^(-))、p H、土壤砂粒含量和粉粒含量的差异而发生改变,影响程度依次是:(NH_(4)^(+)∶NO_(3)^(-))>p H>砂粒含量>粉粒含量.通过揭示土壤盐分升高对不同土地利用类型下N_(2)O排放的刺激作用,明确了环境因子和盐分交互作用对N_(2)O排放的影响,对土壤盐渍化地区N_(2)O排放预防阻控和环境改善具有重要科学意义.

关键词： N_(2)O累积排放量盐渍化反硝化作用土地利用方式 Metafor软件包

在线全文

学校读者我要写书评

暂无评论

智能网联车辆加速车道类人化汇入控制研究

中国公路学报 2024年第3期37卷 134-146页

作者：谷梦路葛振振王畅苏彦奇郭应时长安大学汽车学院陕西西安710064 长安大学汽车运输安全保障技术交通行业重点实验室陕西西安710064

为研究智能网联车辆(Intelligent Connected Vehicle, ICV)与高速公路主线传统人工驾驶车辆(Human-driven Vehicle, HDV)交互时通过高速公路加速车道的汇入控制算法,提出了一种融合随机森林(Random Forest, RF)算法和深度Q网络(Deep Q-n... 详细信息

为研究智能网联车辆(Intelligent Connected Vehicle, ICV)与高速公路主线传统人工驾驶车辆(Human-driven Vehicle, HDV)交互时通过高速公路加速车道的汇入控制算法,提出了一种融合随机森林(Random Forest, RF)算法和深度Q网络(Deep Q-network, DQN)算法的ICV汇入控制模型(DQN-RF)。首先,建立路侧数据采集平台,采集了中国G70高速公路加速车道汇入区域HDV的真实汇入过程数据。其次,考虑汇入环境车辆历史数据流和汇入车在加速车道的汇入紧迫度,建立了基于RF算法的类人化汇入决策模型。采用城市交通仿真(Simulation of Urban Mobility, suMO)平台搭建了高速公路加速车道ICV汇入场景,并基于Python语言建立了ICV汇入控制深度强化学习测试脚本环境,建立了基于DQN的纵向加速度控制算法。最后,将RF汇入决策模型嵌入DQN纵向加速度控制算法中,实现了ICV汇入决策和纵向加速度控制的融合。将suMO内置的LC2013换道模型与DQN模型融合为DQN-LC2013模型,作为基线模型与DQN-RF模型进行对比。研究结果表明:相较于未考虑类人化汇入决策的DQN-LC2013模型,考虑类人化汇入决策的DQN-RF模型获得了更高的奖励值;当加速度动作取值空间为[-1,2] m·s^(-2)时,DQN-RF和DQN-L2013控制下的ICV通过汇入控制区域的平均加速度分别为0.55、0.09 m·s^(-2),通过汇入控制区域的速度分别为21.4、19.7 m·s^(-1);DQN-RF模型控制下ICV无停车等待现象,DQN-LC2013控制下ICV在100次汇入过程中出现了7次停车等待。提出的DQN-RF汇入控制模型可以实现类人化的驾驶决策,提高ICV通过汇入控制区域的效率和汇入成功率,可用于ICV通过高速公路加速车道汇入区域的汇入决策和纵向加速度控制。

关键词：交通工程汇入控制模型 DQN-RF 智能网联汇入车辆加速车道 suMO仿真

基于VMD-ICA的水下激光雷达抗散射信号处理方法

在线全文

学校读者我要写书评

暂无评论

物理学报 2024年第9期73卷 110-115页

作者：李朝锋王振刘欣宇杨苏辉徐震樊超阳北京理工大学光电学院北京100081 中国电子科技集团公司第三十四研究所桂林541000

提出一种基于变分模态分解(VMD)与独立元分析(ICA)相结合的水下信号处理方法.该方法运用VMD将一组回波信号分解为多组按照频率高低顺序排列的本征模态信号.然后,将这些模态信号作为ICA的观测矩阵,以确保分离所得目标回波信号的完整性.... 详细信息

提出一种基于变分模态分解(VMD)与独立元分析(ICA)相结合的水下信号处理方法.该方法运用VMD将一组回波信号分解为多组按照频率高低顺序排列的本征模态信号.然后,将这些模态信号作为ICA的观测矩阵,以确保分离所得目标回波信号的完整性.该方法提出将分解所得的各层模态信号与原信号进行相关性和信杂比比较,以确定其分解层数.应用ICA方法对散射与目标回波进行分离,从而恢复强散射水体中的微弱目标回波,大大提高其测距精度.进行不同衰减长度水体的532 nm调频连续光水下测距实验.经实验验证,该信号处理方法在激光输出功率2.3 W时,成功实现对9个衰减长度内目标的测量,使用算法将测距精度由16 cm提升至5 cm以内.

关键词：变分模态分解独立元分析频谱反馈

维普期刊数据库博看期刊

Energy storage optimization of ferroelectric ceramics during phase-transition process of amorphous/nanocrystalline and polycrystalline by using a phaseffeld model for dielectric breakdown

在线全文

学校读者我要写书评

暂无评论

Journal of Advanced Dielectrics 2024年第1期14卷 33-41页

作者： suilong Huang Jianwen Chen zhen su Xiucai Wang Wenbo Zhu Wenjun Chen Xinmei Yu Peng Xiao School of Electronic and Information Engineering Foshan University Foshan 528000P.R.China School of Mechatronic Engineering and Automation Foshan University Foshan 528000P.R.China China-Australia Institute for Advanced Materials and Manufacturing Jiaxing University Jiaxing 314001P.R.China School of Materials Science and Hydrogen Energy Foshan University Foshan 528000P.R.China School of Physics and Optoelectronic Engineering Foshan University Foshan 528000P.R.China

Ferroelectric ceramics have the potential to be widely applied in the modern industry and military power systems due to their ultrafast charging/discharging speed and high energy *** the structural design and electrical properties of ferroelectric capacitor,it is still a challenge to ffnd out the optimal energy storage of ferroelectric ceramics during the phase-transition process of amorphous/nanocrystalline and *** this work,a ffnite element model suitable for the multiphase ceramic system is constructed based on the phase ffeld breakdown *** nonlinear coupling relationship of multiple physical ffelds between multiphase ceramics was taken into account in this *** basic structures of multiphase ceramics are generated by using the Voronoi diagram construction *** speciffed structure of multiphase ceramics in the phase-transition process of amorphous/nanocrystalline and polycrystalline was further obtained through the grain boundary diffusion *** simulation results show that the multiphase ceramics have an optimal energy storage in the process of amorphous polycrystalline transformation,and the energy storage density reaches the maximum when the crystallinity is 13.96%and the volume fraction of grain is 2.08%.It provides a research plan and idea for revealing the correlation between microstructure and breakdown characteristics of multiphase *** simulation model realizes the nonlinear coupling of the multiphase ceramic mesoscopic structure and the phase ffeld *** provides a reference scheme for the structural design and performance optimization of ferroelectric ceramics.

关键词： Ferroelectric ceramics phase transition phase-field model dielectric breakdown energy storage