检索结果-南通市图书馆

Clinical and genetic risk factors for venous thromboembolismin Chinese population

在线全文

学校读者我要写书评

暂无评论

Frontiers of Medicine 2010年第1期4卷 29-35页

作者： Chen WANG zhen-guo zhai Ying H.SHEN Lan ZHAO Beijing Institute of Respiratory Medicine Beijing Chao-Yang HospitalCapital Medical UniversityBeijing 100020China Baylor College of Medicine HoustonTX 77004USA Department of Experimental Medicine and Toxicology Hammersmith HospitalImperial College LondonLondon W120NNUK

Venous thromboembolism(VTE),including deep vein thrombosis and pulmonary embolism,carries signiﬁcant mortality and *** most important and effective way to reduce VTE incidence is to identify the patients at risk and give necessary *** is a multifactorial and complicated *** risk factors for VTE include surgery and trauma,acute medical illness,active cancer and *** factors increase susceptibility to the disease and are useful in predicting the development of ***-gene and gene-environment interactions alter and magnify the clinical picture in this *** brief review summarizes some selected clinical and genetic risk factors for VTE based on the current research in China.

关键词： risk factor stroke prothrombin plasminogen activator inhibitor type-1 polymorphism thrombophilia biomarker

Endovascular Catheter-guided Forceps Biopsy for the Diagnosis of Suspected Pulmonary Artery Sarcoma： A Preliminary Study of Eight Cases

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2016年第18期129卷 2246-2249页

作者： Wan-Mu Xie zhen-guo zhai Le-Feng Wang Jun Wan Yuan-Hua Yang Chen Wang Department of Respiratory and Critical Care Medicine China-Japan Friendship Hospital Beijing 100029 China Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders Beijing 100020 China Department of Cardiology Beijing Chao-Yang Hospital Capital Medical University Beijing 100020 China Department of Respiratory and Critical Care Medicine Beijing Chao-Yang Hospital Capital Medical University Beijing 100020 China

Pulmonary artery sarcoma （PAS） is a rare malignant tumor that originates from the pulmonary artery （PA） with a poor prognosis,Early diagnosis and radical surgical resection offer the only chance for survival As most PA sarcomas involve the PA trunk, making a preoperative histopathological diagnosis is quite difficult. So far, most PAS cases were reported with diagnosis made either at autopsy or intraoperatively with frozen sections.

关键词： Biopsy Histopathological Diagnosis Pulmonary Artery Sarcoma

Incidence of Pleural Effusion in Patients with Pulmonary Embolism

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2015年第8期128卷 1032-1036页

作者： Min Liu Ai Cui zhen-guo zhai Xiao-Juan guo Man Li Lei-Lei Teng Li-Li Xu Xiao-Juan Wang zhen Wang Huan-Zhong Shi Department of Radiology Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital Capital Medical University Beijing 100020 China Department of Respiratory and Critical Care Medicine Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital Capital Medical University Beijing 100020 China

Background： No data on the incidence ofpleural effusion （PE） in Chinese patients with pulmonary embolism are available to date. The aim of the current study was to investigate the frequency of PE in a Chinese population of patients with pulmonary embolism. Methods： This was a retrospective observational single-center study. All data of computed tomography pulmonary angiography （CTPA） performed over 6-year period on adult patients with clinically suspected pulmonary embolism were analyzed. Results： From January 2008 until December 2013, PE was identified in 423 of 3141 patients （13.5%） with clinically suspected pulmonary embolism who underwent CTPA, The incidence of PE in patients with pulmonary embolism （19.9%） was significantly higher than in those without embolism （9.4%）（P 〈 0.001 ）. Majority of PEs in pulmonary embolism patients were small to moderate and were unilateral. The locations of emboli and the numbers of arteries involved, CT pulmonary obstruction index, and parenchymal abnormalities at CT were not associated with the development of PE, Conclusions： PEs are present in about one fifth of a Chinese population of patients with pulmonary embolism, which are usually small, unilateral, and unsuitable for diagnostic thoracentesis.

关键词： Computed Tomography Pulmonary Angiography Pleural Effusion Pulmonary Embolism

Clinical Study of Acute Vasoreactivity Testing in Patients with Chronic Thromboembolic Pulmonary Hypertension

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2017年第4期130卷 382-391页

作者： Qi-Xia Xu Yuan-Hua Yang Jie Geng zhen-guo zhai Juan-Ni Gong Ji-Feng Li Xiao Tang Chen Wang Department of Respiratory and Critical Care Medicine Beijing Institute of Respiratory Medicine Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders Beijing Chao-Yang Hospital Capital Medical University Beijing 100020 China Department of Respiratory Medicine Capital Medical University Beijing 100069 China Department of Respiratory and Critical Care Medicine The First Affiliated Hospital of Bengbu Medical College Bengbu Anhui 233004 China Department of Respiratory and Critical Care Medicine China-Japan Friendship Hospital Beijing 100029 China National Clinical Research Center for Respiratory Diseases Beijing 100730 China

Background： The clinical significance of acute vasoreactivity testing （AVT） in patients with chronic thromboembolic pulmonary hypertension （CTEPH） remains unclear. We analyzed changes in hemodynamics and oxygenation dynamics indices after AVT in patients with CTEPH using patients with pulmonary arterial hypertension （PAH） as controls. Methods： We analyzed retrospectively the results of AVT in 80 patients with PAH and 175 patients with CTEPH registered in the research database of Beijing Chao-Yang Hospital between October 2005 and August 2014. Demographic variables, cardiopulmonary indicators, and laboratory findings were compared in these two subgroups. A long-term follow-up was conducted in patients with CTEPH. Between-group comparisons were performed using the independent-sample t-test or the rank sum test, within-group comparisons were conducted using the paired t-test or the Wilcoxon signed-rank test, and count data were analyzed using the Chi-squared test. Survival was estimated using the Kaplan-Meier method and log-rank test. Results： The rates of positive response to AVT were similar in the CTEPH （25/175, 14.3%） and PAH （9/80, 11.3%） groups （P 〉 0.05）. Factors significantly associated a positive response to AVT in the CTEPH group were level of N-terminal pro-brain natriuretic peptide （〈1131.000 ng/L）, mean pulmonary arterial pressure （mPAE ≤44.500 mmHg）, pulmonary vascular resistance （PVR, 〈846.500 dyn＇s-1·m-5）, cardiac output （CO,≥3.475 L/rain）, and mixed venous oxygen partial pressure （PvO2, ≥35.150 mmHg）. Inhalation of iloprost resulted in similar changes in mean blood pressure, mPAE PVR, systemic vascular resistance, CO, arterial oxygen saturation （SaO2）, mixed venous oxygen saturation, partial pressure of oxygen in arterial blood （PaO2）, PvO2, and intrapulmonary shunt （Qs/Qt） in the PAH and CTEPH groups （all P 〉 0.05）. The survival time in patients with CTEPH with a negative response to AVT was somewhat shorter than that in AVT-responders although the di

关键词： Acute Vasoreactivity Testing Calcium ChannelBlocker Treatment Chronic Thromboembolic PulmonaryHypertension Iloprost

Pulmonary Hypertension in Glycogen Storage Disease Type II

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2018年第11期131卷 1375-1376页

作者： Hui-Ping Li Wan-Mu Xie XU Huang Xin Lu zhen-guo zhai Qing-Yuan Zhan Chen Wang National Clinical Research Center for Respiratory Disease Beijing 100029 China Center for Respiratory Disease China-Japan Friendship Hospital Beijing 100029 China Department of Pulmonary and Critical Care Medicine China-Japan Friendship Hospital Beijing 100029 China Department of Rheumatology China-Japan Friendship Hospital Beijing 100029 China

To the Editor： Glycogen storage disease （GSD） is a group of inherited disorders with abnormal glycogen deposition, Pulmonary hypertension （PH） is a rare complication of GSD with unclear etiology. Since the pioneer description in 1980, only a few cases of GSD-associated PH have been reported. Here, we reported a Chinese case with informed consent by the patient and the guardian.

关键词： POMPE DISEASE

Bivariate attribution of the compound hot and dry summer of 2022 on the Tibetan Plateau

在线全文

学校读者我要写书评

暂无评论

Science China Earth Sciences 2024年第7期67卷 2122-2136页

作者： Baiquan ZHOU Panmao zhai zhen LIAO State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesChina Meteorological AdministrationBeijing 100081China

The extraordinarily high temperatures experienced during the summer of 2022 on the Tibetan Plateau(TP)demand attention when compared with its typical climatic *** absence of precipitation alongside the elevated temperatures resulted in 2022 being the hottest and driest summer on record on the TP since at least *** the susceptibility of the TP to climate change,this study employed large-ensemble simulations from the HadGEM3-A-N216 attribution system,together with a copula-based joint probability distribution,to investigate the influence of anthropogenic forcing,primarily global greenhouse gas emissions,on this unprecedented compound hot and dry event(CHDE).Findings revealed that the return period for the 2022 CHDE on the TP exceeds 4000 years,as determined from the fitted joint distributions derived using observational data spanning *** CHDE was directly linked to large-scale circulation anomalies,including the control of equivalent-barotropic high-pressure anomalies and the northward displacement of the subtropical westerly jet ***,anthropogenic forcing has,to some extent,promoted the surface warming and increased variability in precipitation on the TP in summer,establishing conditions conducive for the 2022 CHDE from a long-term climate change *** return period for a 2022-like CHDE on the TP was estimated to be approximately 283 years(142-613 years)by the large ensemble forced by both anthropogenic activities and natural ***,ensemble simulations driven solely by natural forcing indicated that the likelihood of occurrence of a 2022-like CHDE was almost *** outcomes underscore that the contribution of anthropogenic forcing to the probability of a 2022-like CHDE was 100%,implying that without anthropogenically induced global warming,a comparable CHDE akin to that observed in 2022 on the TP would not be possible.

关键词： Compound hot and dry event Tibetan Plateau Bivariate event attribution Anthropogenic forcing

Incidence and Clinical Characteristics of Pulmonary Hypertension in Patients with Idiopathic Pulmonary Fibrosis

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2015年第7期128卷 896-901页

作者： Wei Yan Li-Ying Peng Cheng-Jun Ban Xue-Feng Xu Min Zhu Yan Liu Shu Zhang zhen-guo zhai Chen Wang Hua-Ping Dai Department of Respiratory and Critical Care Medicine Beijing Chao-Yang Hospital Capital Medical University Beijing 100020 China Beijing Key Laboratory of Respiratory and Pulmonary Circulation Beijing Institute of Respiratory Medicine Beijing 100020 China

Background： Pulmonary hypertension （PH） frequently complicates the course of idiopathic pulmonary fibrosis （IPF） patients and is associated with significantly worse outcomes. The aim of the present study was to investigate the incidence of PH in IPF patients and evaluate the correlation between clinical parameters and systolic pulmonary artery pressure （sPAP）. Methods： Hospitalized patients with IPF, who were evaluated for sPAP by Doppler echocardiography from January 2004 to December 2011, were enrolled in our study. Patients were defined as PH by an estimated sPAP 〉 50 mmHg and graded as PH likely, PH possible and PH unlikely, based on the 2009 European Society of Cardiology/European Respiratory Society PH Guidelines. The correlations between clinical parameters and sPAP were analyzed by multiple linear regression. Results： Totally, 119 IPF patients were enrolled in our study and 28 （23.5%）, 20 （16.8%） and 71 （59.7%） patients were PH likely, PH possible and PH unlikely, respectively. Borg dyspnea score was positively correlated with sPAP, r = 0.467, P 〈 0.001. Oxygen saturation was negatively correlated with sPAP, r = -0.416, P 〈 0.001. Diffusing capacity of the lung for carbon monoxide percentage predicted was negatively correlated with sPAP, r = -0.424, P = 0.003. N-terminal fragment of pro-brain natriuretic peptide and pulmonary artery width was positively correlated with sPAP, r = 0.452, P = 0.011 and r= 0.513, P 〈 0.001, respectively. Conclusions： The incidence of PH in IPF patients was 23.5% in a single center of China. PH may worsen the dyspnea, right heart dysfunction and decrease the life quality of the patients with IPF.

关键词： Idiopathic Pulmonary Fibrosis: Incidence Pulmonary Hypertension

Lead-free metal halide scintillator materials for imaging applications

在线全文

学校读者我要写书评

暂无评论

Science China(Information Sciences) 2024年第8期67卷 85-101页

作者： Junzhe LIN Dan guo Tianrui zhai Department of Physics and Optoelectronic Engineering Beijing University of Technology

High-energy radiation detection and imaging technology has significant applications in highenergy physics research, medical imaging, and industrial monitoring. Lead-free metal halides exhibit exceptional potential for conducting indirect detection of high-energy radiation due to their characteristics of low toxicity, strong stability, high light yield, and large Stokes shift. This paper reviews the most recent advances in lead-free metal halide scintillator materials for X-ray imaging. Subsequently, it lists the most important parameters of scintillator performance and introduces the production procedures for single crystal, powder,and nanocrystal scintillators. Furthermore, it discusses the manufacturing of scintillator films with improved performance, focusing on large-area flexible scintillator films and the coupling with microstructures. Finally,it discusses current challenges and opportunities for enhancing X-ray imaging using lead-free metal halide scintillator materials.

关键词： film imaging lead-free metal halide luminescence scintillators

Extraordinary hot extreme in summer 2022 over the Yangtze River basin modulated by the La Nina condition under global warming

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Advances in Climate Change Research 2024年第1期15卷 21-30页

作者： zhen LIAO Yu-Feng YUAN Yang CHEN Pan-Mao zhai State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesBeijing 100081China

A widespread and prolonged hot extreme hit the Yangtze River basin in summer 2022,with 300 sites established new temperature records and nearly 96%stations endured more than 40 hot *** the perspective of the combination effect of the global warming and La Nina condition,potential mechanisms of the hot extreme were *** a record-breaking hot extreme was caused by an extremely strong and westward-shifted western Pacific subtropical high(WPSH).The global warming effect contributed primarily to the abnormal hot days in the Yangtze River basin,coupled with the modulation of the La Nina *** sea surface temperature anomaly pattern under La Nina condition favored more convection activities over the western Pacific,encouraging an enhanced and westward-extended *** addition,an observation-based attribution analysis indicates that anthropogenic warming may increase the probability of such extensively persistent hot extremeby1.8 times.

关键词： Hot extreme The Yangtze River basin Global warming Tropical Pacific forcing