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Postoperative abdominal herpes zoster complicated by intestinal obstruction:A case report

World Journal of Clinical Cases 2024年第6期12卷 1138-1143页

作者： zhen-yu dong Rui-Xian Shi Xiao-Biao Song Ming-yue Du Ji-Jun Wang Department of General Surgery Baotou Central HospitalBaotou 014040Inner Mongolia Autonomous RegionChina Department of General Surgery Baotou Medical CollegeBaotou 014040Inner Mongolia Autonomous RegionChina Department of Neurology Baotou Central HospitalBaotou 014040Inner Mongolia Autonomous RegionChina Department of Neurology Inner Mongolia Medical UniversityHohhot 010110Inner Mongolia Autonomous RegionChina

BACKGROUND Intestinal obstruction is a common occurrence in clinical ***,the occurrence of herpes zoster complicated by intestinal obstruction after abdominal surgery is exceedingly *** the diagnostic and treatment process,clinicians consider it crucial to identify the primary causes of its occurrence to ensure effective treatment and avoiding *** SUMMARY Herein,we present the case of a 40-year-old female patient with intestinal obstruction who underwent laparoscopic appendectomy and developed herpes zoster after *** the patient's clinical manifestations and relevant laboratory tests,it was suggested that the varicella zoster virus reactivated during the latent period after abdominal surgery,causing herpes ***,the herpes virus invaded the visceral nerve fibers,causing gastrointestinal dysfunction and loss of intestinal peristalsis,which eventually led to intestinal *** patient was successfully treated through conservative treatment and antiviral therapy and subsequently discharged from the *** Pseudo-intestinal obstruction secondary to herpes zoster infection is difficult to distinguish from mechanical intestinal obstruction owing to various *** cases of inexplicable intestinal obstructions,considering the possibility of a viral infection is essential to minimize misdiagnosis and missed diagnoses。

关键词： Herpes zoster Pseudo-intestinal obstruction Ogilvie syndrome Peripheral motor neuropathy Case report

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超声造影联合增强CT对肝局灶性结节与小肝细胞癌早期的临床鉴别诊断价值

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医学信息 2024年第11期37卷 139-142页

作者：董振宇天津市蓟州区人民医院肿瘤综合诊疗中心

目的探究超声造影（CEUS）联合增强CT(CECT)对肝局灶性结节（FNH）与小肝细胞癌（SHCC）早期的鉴别诊断价值。方法以2000年3月-2023年3月天津市蓟州区人民医院收治的FNH患者（50例）与早期SHCC患者（32例）为研究对象，依次行CEUS与C... 详细信息

目的探究超声造影（CEUS）联合增强CT(CECT)对肝局灶性结节（FNH）与小肝细胞癌（SHCC）早期的鉴别诊断价值。方法以2000年3月-2023年3月天津市蓟州区人民医院收治的FNH患者（50例）与早期SHCC患者（32例）为研究对象，依次行CEUS与CECT检查，比较FNH患者与SHCC患者的CEUS参数（开始消退时间、峰值减半时间、下降支斜率）及CECT特征（开始增强时间、增强达峰时间、开始减退时间），统计CEUS、CECT及两者联合检测对两种疾病的检出结果，并分析其鉴别诊断价值（诊断准确性、敏感度与特异度）。结果在CEUS检查中，FNH患者的开始消退时间、峰值减半时间晚于SHCC患者，下降支斜率小于SHCC患者（P0.05），但FNH患者的增强达峰时间、开始消退时间晚于SHCC患者（P<0.05）。CEUS联合CECT检测FNH检出率、SHCC检出率高于其单一检测（P<0.05）。CEUS联合CECT检测对FNH与早期SHCC的诊断准确性、敏感度与特异度高于其单一检测（P<0.05）。结论 CEUS、CECT在FNH与SHCC早期鉴别诊断中具有确切作用，二者联合应用诊断价值更佳。

关键词：肝局灶性结节增生小肝细胞癌超声造影增强CT扫描鉴别诊断

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高温胁迫下厚壳贻贝(Mytilus coruscus)消化腺代谢组学研究

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海洋与湖沼 2024年第1期55卷 171-181页

作者：郭锋王玉霞董震宇姚荣辉王伟峰叶莹莹严小军郭宝英国家海洋设施养殖工程技术研究中心浙江舟山316022 浙江海洋大学海洋科学与技术学院浙江舟山316022

在全球变暖的背景下,海水温度不断升高、海洋暖化逐渐加剧,高温严重影响着海洋生物的各种生命过程,但对于海洋双壳贝类如何应对热应激的研究仍然不足。为此,开展了以18℃(CT)为对照组在26℃(ST)和33℃(HT)下对厚壳贻贝消化腺组织进行了... 详细信息

在全球变暖的背景下,海水温度不断升高、海洋暖化逐渐加剧,高温严重影响着海洋生物的各种生命过程,但对于海洋双壳贝类如何应对热应激的研究仍然不足。为此,开展了以18℃(CT)为对照组在26℃(ST)和33℃(HT)下对厚壳贻贝消化腺组织进行了急性热胁迫下的代谢组学分析,以便于研究其代谢反应。采用LC-MS/MS技术,并结合生物信息分析手段对差异代谢物进行筛选,并分析确定相关的代谢通路的变化,共有2532种代谢物在厚壳贻贝消化腺中被鉴定。KEGG富集分析用于探索差异代谢物的潜在代谢途径,共有29条代谢通路被显著富集,与对照组相比,ST组显著富集于牛磺酸和次牛磺酸代谢、神经活性配体-受体相互作用、鞘脂类代谢和视黄醇代谢等代谢通路;HT组显著富集于酪氨酸代谢、亚油酸代谢、丙氨酸新陈代谢、酪氨酸代谢、色氨酸代谢、苯丙氨酸代谢等代谢通路。研究结果显示,厚壳贻贝消化腺主要通过调节色氨酸代谢、酪氨酸代谢、鞘脂代谢、苯丙氨酸代谢、氧化磷酸化,脂肪酸、赖氨酸降解等信号通路应对热应激,从而帮助维持身体内部环境的稳定状态。上述研究为多视角探究厚壳贻贝耐热机制与应对环境中温度变化的适应性进化提供理论基础。

关键词：厚壳贻贝(Mytilus coruscus) 消化腺高温胁迫代谢组学

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经肌间隙入路与经皮入路后路短节段内固定治疗胸腰椎骨折对椎旁肌的影响比较研究

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新疆中医药 2024年第2期42卷 4-7页

作者：王荣李建江董振宇黄异飞新疆医科大学附属中医医院新疆乌鲁木齐830001

目的分析比较经肌间隙入路(Wiltse入路)与经皮入路后路短节段内固定治疗胸腰椎骨折对椎旁肌损伤的比较。方法选取2017年3月~2018年3月新疆维吾尔自治区中医医院收治的胸腰段骨折患者35例,据患者意愿不同,采用经经肌间隙入路(Wiltse入路... 详细信息

目的分析比较经肌间隙入路(Wiltse入路)与经皮入路后路短节段内固定治疗胸腰椎骨折对椎旁肌损伤的比较。方法选取2017年3月~2018年3月新疆维吾尔自治区中医医院收治的胸腰段骨折患者35例,据患者意愿不同,采用经经肌间隙入路(Wiltse入路)与经皮入路后路短节段内固定术治疗,两组患者伤椎均置钉,并分为A组(18例)、B组(17例)。随访1年,比较两组的手术指标:术前及术后末次随访胸腰椎CT的椎旁肌平均最大横截面积,术前与术后1 d、3 d的血清磷酸肌酸激酶(CK)的含量,疼痛视觉模拟评分(VAS)、Oswestry功能障碍指数(ODI)评分,并评价两组手术治疗的安全性。结果术后1年随访,A组较B组的椎旁肌平均最大横截面积大,A组术后1 d、3 d的血清磷酸肌酸激酶(CK)的含量较B组低,术后1 d、3 d组间比较有统计学差异(P0.05)。两组术后均无切口感染及钉棒松动、断裂和脱落情况。结论经皮经伤椎短节段后路内固定治疗胸腰椎骨折的对椎旁肌的影响更小,中远期的临床疗效显著。

关键词：经皮微创入路经肌间隙入路(Wiltse入路) 胸腰椎骨折疗效

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Biomimetic design of highly flexible metal oxide nanofibrous membranes with exceptional mechanical performance for superior phosphopeptide enrichment

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Nano Research 2024年第5期17卷 4270-4278页

作者： Xue Mao zhen-zhen Li dong-Lian Hao Wei-dong Han Gao-Peng Li Yao-yu Wang Kun Zhang School of Textile Science and Engineering Key Laboratory of Functional Textile Material and Product(Ministry of Education)Xi’an Polytechnic UniversityXi’an 710048China Key Laboratory of Magnetic Molecules&Magnetic Information Materials of the Ministry of Education School of Chemistry&Material ScienceShanxi Normal UniversityTaiyuan 030031China Department of Clinical Laboratory The Second Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710004China Shanghai iProteome Biotechnology Co. LtdShanghai 201210China College of Chemistry&Materials Science Northwest UniversityXi'an 710127China

Developing free-standing and mechanical robust membrane materials capable of superior enrichment of phosphopeptides for analyzing and identifying the specific phosphoproteome of cancer cells is significant in understanding the molecular mechanisms of cancer development and exploring new therapeutic approaches,but still a significant challenge in materials *** this end,we firstly constructed highly flexible ZrTiO_(4) nanofibrous membranes(NFMs)with excellent mechanical stability through a cost-effective and scalable electrospinning and subsequent calcination ***,to further increase the enrichment capacity of the phosphopeptide,the biomimetic TiO_(2)@ZrTiO_(4) NFMs with root hair or leaf like branch microstructure are developed by the hydrothermal post-synthetic modification of ZrTiO_(4) NFMs through growing unfurling TiO_(2) nanosheets onto the ZrTiO_(4) ***,remarkable flexibility and mechanical stability enable the resulting TiO_(2)@ZrTiO_(4) NFMs excellent practicability,while the biomimetic microstructure allows it outstanding enrichment ability of the phosphopeptide and identification ability of the specific phosphoproteins in the digest of cervical cancer ***,6770 phosphopeptides can be enriched by TiO_(2)@ZrTiO_(4) NFMs(2205 corresponding phosphoproteins can be identified),and the value is much higher than that of ZrTiO_(4) NFMs(6399 phosphopeptides and 2132 identified phosphoproteins)and commercial high-performance TiO_(2) particles(4525 phosphopeptides and 1811 identified phosphoproteins).These results demonstrate the super ability of TiO_(2)@ZrTiO_(4) NFMs in phosphopeptide enrichment and great potential for exploring the pathogenesis of cancer.

关键词： inorganic nanofibers flexible ceramic nanofibrous membranes biomimetic materials exceptional mechanical performance flexibility

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Doping engineering of iron oxide nanoparticles towards high performance and biocompatible T_(1)-weighted MRI contrast agents

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Rare Metals 2024年第1期43卷 298-308页

作者： Xue Xu Ping-Li dong yu-yun Chai Run Yang zhen-Hui Ma Chi-Chong Lu Department of Chemistry College of Chemistry and Materials EngineeringBeijing Technology and Business UniversityBeijing 100048China Department of Physics Beijing Technology and Business UniversityBeijing 100048China

Extremely small-sized iron oxide nanoparticles(IONPs) are of great interest in magnetic resonance imaging(MRI) due to their biosafety as an alternative to clinical gadolinium(Ⅲ) complexes-based contrast *** when the particle size is less than 10 nm,it has strong diffusion ability and deep penetration distance in tumor *** doping can significantly enhance the T_(1)contrast effect of nanoparticles by regulating the surface exposed ***,the nucleation and growth processes of multi-component synthesis systems are complex and difficult to be accurately controlled,leading to great challenges in the synthesis of ultra-small-sized nanoparticles with different components and ***,extremely smallsized superparamagnetic gadolinium-doped iron oxide nanoparticles(GdIONPs,Gd_(x)Fe_(3-x)O_(4) NPs) with adjustable doping amount and controllable size in the range of 3.5-7.5 nm were synthesized by thermal ***,as-synthesized GdIONPs were surface modified with a highly water-soluble and biocompatible carboxyl-polyethylene glycol-phosphoric acid ligand with high binding ***_(0.65)Fe_(2.35)O_(4) NPs exhibited very high r_(1) relaxivity of 10.6 mmol^(-1)·L·s^(-1) in terms of all metal concentrations and 49.0 mmol^(-1)·L·s^(-1) in terms of gadolinium alone,respectively,3 and 14 times higher than clinical T_(1) contrast agents(Gd-DTPA).GdIONPs can continuously obtain high resolution images of blood vessels,and can be used as an efficient and multifunctional contrast agent for MR T_(1)*** stable and efficient doping strategy provides an easy and effective method to individually optimize the magnetic properties of complex oxides and their relaxation effects for a variety of biomedical applications.

关键词： Iron oxide nanoparticles Small size Magnetic resonance imaging Substitutional doping Gd dopant

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Recent progress in self-propelled particles

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Journal of Hydrodynamics 2024年第1期36卷 61-77页

作者： zhen-yu Ouyang Jian-zhong Lin Laboratory of Impact and Safety Engineering Ministry of EducationNingbo UniversityNingbo315201China Department of Mechanics State Key Laboratory of Fluid Power and Mechatronic SystemsZhejiang UniversityHangzhou310027China

Self-propelled particles are commonly found in a large number of planktonic organisms such as bacteria,fungi,and algae in nature,and researchers have taken a long interest in exploring their swimming mechanisms for more than a *** in the past 20 years,with the development of computational fluid dynamics and flow display technology,as well as the need for the design of synthetic self-propelled particles and micro-swimming devices,self-propelled particles have become the forefront and hotspot of current research in the field of fluid *** paper first introduces the swimming characteristics of common self-propelled particles,leading to a classic“squirmer”type self-propelled particle *** this basis,a systematic introduction and summary of the theoretical and numerical simulation research of“squirmer”will be ***,the main challenges and opportunities faced by the current research will be summarized.

关键词： Self-propelled particles multiphase flow hydrodynamic interaction

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Design and Gait Planning of a Worm-inspired Metameric Robot for Pipe Crawling

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Journal of Bionic Engineering 2024年第3期21卷 1265-1277页

作者： yu Liu Qingbiao Shi zhen Chen Pen-Tung Sah Institute of Micro-Nano Science and Technology Xiamen UniversityXiamen361102China

The earthworm has been attracted much attention in the research and development of biomimetic robots due to their unique locomotion mechanism,compact structure,and small motion *** paper presents a new design and prototype of a worm-inspired metameric robot with a movement pattern similar to that of *** robot consists of multiple telescopic modules connected in series through joint *** telescopic module mimics the contraction and elongation motion modes of the earthworm segments.A kinematic and dynamic analysis is conducted on the telescopic module,and an input torque calculation method is provided to ensure sufficient friction between the robot and the pipe *** gait modes of the prototype robot for straight and turning locomotion are introduced,and these modes are extended to robots constructed by different numbers of telescopic *** addition,a method is proposed to increase the friction between the robot and the pipe wall in the aforementioned gait modes without changing the robot structure,thereby improving the robot’s motion ability in *** theoretical model of gait modes has also been validated through gait *** findings of this paper would provide a useful basis for the design,modeling,and control of future worm inspired robots.

关键词： Bio-inspired robot Spatial linkage mechanism Kinematics model Peristaltic locomotion

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First Passage Density of Brownian Motion with Two-sided Piecewise Linear Boundaries

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Acta Mathematica Sinica,English Series 2024年第6期40卷 1505-1520页

作者： zhen yu Mao Zai TIAN Center for Applied Statistics School of StatisticsRenmin University of ChinaBeijing 100872P.R.China School of Mathematics and Data Science Changji UniversityChangji 831100P.R.China

The first passage time has many applications in fields like finance,econometrics,statistics,and ***,explicit formulas for the first passage density have only been obtained for a few *** paper derives an explicit formula for the first passage density of Brownian motion with twosided piecewise continuous boundaries which may have some points of *** are used to obtain a simplified formula for estimating the first passage ***,the results are also generalized to the case of two-sided general nonlinear *** can be easily carried out with Monte Carlo method and it is demonstrated for several typical two-sided boundaries that the proposed approximation method offers a highly accurate approximation of first passage density.

关键词： Boundary non-crossing probability first density passage density two-sided piecewise continuous boundaries Brownian motion

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Large-inductance superconducting microstrip photon detector enabling 10 photon-number resolution

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Advanced Photonics 2024年第1期6卷 96-105页

作者： Ling-dong Kong Tian-Zhu Zhang Xiao-yu Liu Hao Li zhen Wang Xiao-Ming Xie Li-Xing You Chinese Academy of Sciences(CAS) Shanghai Institute of Microsystem and Information TechnologyNational Key Laboratory of Materials for Integrated CircuitsShanghaiChina CAS Center for Excellence in Superconducting Electronics ShanghaiChina University of Chinese Academy of Sciences Center of Materials Science and Optoelectronics EngineeringBeijingChina

Efficient and precise photon-number-resolving detectors are essential for optical quantum information *** this,very few detectors have been able to distinguish photon numbers with both high fidelity and a large dynamic range,all while maintaining high speed and high timing *** nanostrip-based detectors excel at counting single photons efficiently and rapidly,but face challenges in balancing dynamic range and ***,we have pioneered the demonstration of 10 true photon-number resolution using a superconducting microstrip detector,with readout fidelity reaching an impressive 98%and 90%for 4-photon and 6-photon events,***,our proposed dual-channel timing setup drastically reduces the amount of data acquisition by 3 orders of magnitude,allowing for real-time photon-number *** then demonstrate the utility of our scheme by implementing a quantum random-number generator based on sampling the parity of a coherent state,which guarantees inherent unbiasedness,robustness against experimental imperfections and environmental noise,as well as invulnerability to *** solution boasts high fidelity,a large dynamic range,and real-time characterization for photon-number resolution and simplicity with respect to device structure,fabrication,and readout,which may provide a promising avenue towards optical quantum information science.

关键词： superconducting microstrips single-photon detector photon-number resolution quantum random number

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