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Amino acids TORC(talk)to anabolism through uncharged tRNA

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Science China(Life Sciences) 2024年第8期67卷 1775-1776页

作者： zhen-zhen ma Shi-Min Zhao The Obstetrics&Gynecology Hospital of Fudan University State Key Laboratory of Genetic EngineeringShanghai Key Laboratory of Metabolic Remodelling and HealthFudan UniversityShanghai 200090China

Anabolism is essential for proliferation as well as to replenish dysfunctional macromolecules in *** to that both substantial building blocks and energy are required for anabolism,cells must double check whether these prerequisites are met before deciding to start *** acids are building blocks of protein synthesis,their sufficiency in cells is closely monitored by several mechanisms,which all are linked to protein synthesis.

关键词： synthesis. synthesis deciding

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Practical effect of different teaching modes in teaching gastrointestinal surgery nursing

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World Journal of Gastrointestinal Surgery 2024年第1期16卷 166-172页

作者： Xiao-juan Rong zhen Ning Department of Nursing Medical College in Jiangxi University of TechnologyNanchang 330098Jiangxi ProvinceChina

BACKGROUND With the continuous development and progress of medical technology,the position of surgical nursing in the field of clinical medicine is becoming in-creasingly *** an important branch of the surgical field,the nursing requirements and difficulty of gastrointestinal surgery are also *** order to improve the teaching quality of nursing care in gastrointestinal surgery,many educators and researchers are actively exploring new teaching *** them,the teaching method case-based learning(CBL),scene-simulated learning(SSL),task-based learning(TBL),combining self-evaluation and training mode is considered as an effective *** method aims to help students to better master knowledge and skills and improve their comprehensive quality by cultivating their self-evaluation *** To explore the practical effect of CBL-SSL-TBL combined with training mode and student self-assessment in nursing teaching of gastrointestinal *** Seventy-one nursing interns in our hospital from December 2020 to December 2021 were *** to different teaching modes,they were divided into observation group CBL-SSL-TBL combined with training mode combined with student self-assessment and control group(conventional teaching mode),of which 36 were in observation group and 35 were in control *** results of operational skills,theoretical knowledge,nursing students'satisfaction,learning effectiveness questionnaire and teaching effect were compared between the two *** Compared between the two groups,the operational skills and theoretical knowledge scores of the observation group were higher than those of the control group,and the difference was statistically significant(P<0.05).Compared between the two groups,the total satisfaction ratio of the observation group was higher than that of the control group,the difference was statistically significant(P<0.05).Compared between the two groups,the observation group was lower tha

关键词： Gastrointestinal surgery Nursing teaching Teaching model Practical effect Learning ability

Theoretical study of aromaticity reversal in dimethyldihydropyrene derivatives

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Chinese Journal of Structural Chemistry 2024年第5期43卷 8-10页

作者： Fangwen Peng zhen Luo Yingjin ma Haibo ma School of Chemistry and Chemical Engineering Nanjing UniversityNanjing210023China Computer Network Information Center Chinese Academy of SciencesBeijing100190China Qingdao Institute for Theoretical and Computational Sciences School of Chemistry and Chemical EngineeringShandong UniversityQingdaoShandong266237China

Aromaticity has always been an intriguing chemistry topic,which is considered to have close relations with materials'stability and chemical reactivity due to special energy *** conjugated cycles,Hückel's rule,proposed in 1931,suggests that annulenes having[4n+2]and[4n]πelectrons present aromatic and antiaromatic characters with closed and open electronic configurations,respectively[1].

关键词： Hückel aromatic reactivity

SDCC: software-defined collective communication for distributed training

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Science China(Information Sciences) 2024年第9期67卷 105-125页

作者： Xin JIN zhen ZHANG Yunshan JIA Yun ma Xuanzhe LIU School of Computer Science Peking University Department of Computer Science and Technology Johns Hopkins University

Communication is crucial to the performance of distributed training. Today's solutions tightly couple the control and data planes and lack flexibility, generality, and performance. In this study, we present SDCC, a software-defined collective communication framework for distributed training. SDCC is based on the principle of modern systems design to effectively decouple the control plane from the data *** abstracts the operations for collective communication in distributed training with dataflow operations and unifies computing and communication with a single dataflow graph. The abstraction, together with the unification, is powerful: it enables users to easily express new and existing collective communication algorithms and optimizations, simplifies the integration with different computing engines(e.g., Py Torch and Tensor Flow) and network transports(e.g., Linux TCP and kernel bypass), and allows the system to improve performance by exploiting parallelism exposed by the dataflow graph. We further demonstrate the benefits of SDCC in four use cases.

关键词： machine learning systems distributed training deep learning collective communication software-defined networking

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Novel process for facile preparation of mesoporous silica-based materials with controllable pore structure from coal fly ash Author links open overlay panel

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Particuology 2024年第8期91卷 128-137页

作者： Jian-ming Gao zhen Li Shujia ma Yuanyuan Zhang Fangqin Cheng Institute of Resources and Environment Engineering State Environmental Protection Key Laboratory of Efficient Utilization Technology of Coal Waste ResourcesShanxi Collaborative Innovation Center of High Value-added Utilization of Coal-related WastesShanxi UniversityTaiyuan 030006China

Extraction of silica from fly ash to produce mesoporous silica materials is one of the most important utilization *** silica could not be synthesized on a large-scale by conventional sol-gel *** this paper,facile preparation of mesoporous silica with controllable pore structure from fly ash by the template-free process via two steps of mineral phase transformation and selective acid etching was *** influence of crystalline structure and acid etching degree on structure of as-synthesized mesoporous silica materials was revealed,as well as mechanism of crystalline structure transformation and pore structure *** results show that mullite and quartz could be transformed into acid-soluble kaliophilite when fly ash reacted with K_(2)CO_(3)at temperature of 800-1100℃.The hexagonal kaliophilite would be transformed into orthorhombic KAlSiO_(4)-O1 phase when the temperature is controlled at 1100℃.Mesoporous silica with specific surface area of 475.93 m^(2)/g and 642.57 m^(2)/g could be synthesized from activated fly ash with kaliophilite and KAlSiO_(4)-O1 phase crystalline *** controlling the degree of acid etching,mesoporous silica materials with different pore structures can be *** paper provides a cost-effective and large-scale process for the preparation of mesoporous silica materials with controllable pore structure from solid waste fly ash.

关键词： Fly ash Mesoporous silica Crystal transformation Acid etching Controllable pore structure

NIR-IIb-triggered photodynamic therapy combined with chemotherapy platform based on rare-earth-doped nanoparticles

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Rare Metals 2024年第7期43卷 3220-3231页

作者： Zhuo Tu Yong Wan juan Ge Chen-Chen Li Tao Liang zhen Li Chemistry and Chemical Engineering Hubei UniversityWuhan 430062China

Photodynamic therapy(PDT),with high spatiotemporal selectivity,minimal side effects and less drug resistance,has emerged as a promising approach for the treatment of ***,inadequate penetration depth and poor efficacy seriously restrict its practical *** address these challenges,we developed a combined therapy platform(RENP@C/D-FA)based on rare-earth-doped nanoparticles(RENPs)with a structure of NaErF_(4):Tm(0.5%)@NaYF_(4),on which photosensitizer Ce6(chlorin e6)and chemo-therapeutic drug(DOX)(doxorubicin)were loaded by encapsulating with an amphiphilic polymer distearoyl phosphatidylethanolamine-polyethylene glycol-folic acid(DSPE-PEG-FA).RENPs with NaErF_(4) as the matrix possess multiple excitation/emission peaks,enabling activation of PDT under near-infrared-Ⅱb(NIR-Ⅱb,1500-1700 nm)excitation and luminescence imaging in NIR-Ⅱb region by absorbing 808 nm near-infrared ***,DOX can be selectively released in the acidic microenvironment of *** from the tumor targeting capability of folic acid,this platform can successfully ablate tumor cells and inhibit tumor growth by combining PDT and *** innovative approach holds great promise as a powerful tool for cancer treatment,showing the potential to revolutionize PDT.

关键词： Photodynamic therapy Rare-earth-doped nanoparticles NIR-IIb Chemotherapy Combined therapy

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One-dimensional molecular co-crystal alloys capable of full-color emission for low-loss optical waveguide and optical logic gate

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Aggregate 2024年第1期5卷 299-308页

作者： zhenhong Qi Yu-juan ma Dongpeng Yan Beijing Key Laboratory of Energy Conversion and Storage materials College of ChemistryKey Laboratory of Radio-pharmaceuticals Ministry of EducationBeijing Normal UniversityBeijingChina

The luminescence color of molecule-based photoactive materials is the key to the applications in lighting and optical *** continuous regulation of emission color in molecular systems is highly desirable but still remains a challenge due to the individual emission band of purely organic ***,a novel alloy strategy based on molecular co-crystals is *** adjusting the molar ratio of pyrene(Py)and fluorathene(Flu),three types of molecular co-crystal alloys(MCAs)assemblies are prepared involving Py-Flu-OFN-x%,Py-Flu-TFP-x%,Py-Flu-TCNB-x%.Multiple energy level structure and Förster resonance energy transfer(FRET)process endow materials with tunable full-spectra emission color in visible ***,these MCAs and co-crystals can be successfully applied to low optical loss waveguide and optical logic gate by virtue of all-color luminescence from blue across green to red,together with smooth surface of onedimensional microrods,which show promising applications as continuous light emitters for advance photonics applications.

关键词： full-color emission microrods molecular co-crystal optical waveguide organic alloys

An improved pulse coupled neural networks model for semantic IoT

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Digital Communications and Networks 2024年第3期10卷 557-567页

作者： Rong ma zhen Zhang Yide ma Xiping Hu Edith C.H.Ngai Victor C.M.Leung School of Information Science and Engineering Lanzhou UniversityLanzhou 730000China School of Medical Technology Beijing Institute of TechnologyBeijing100081China Department of Electrical and Electronic Engineer The University of Hong KongHong Kong 999077China College of Computer Science and Software Engineering Shenzhen UniversityShenzhen 518060China Department of Electrical and Computer Engineering the University of British ColumbiaVancouverBC V6T 1Z4Canada

In recent years,the Internet of Things(IoT)has gradually developed applications such as collecting sensory data and building intelligent services,which has led to an explosion in mobile data ***,with the rapid development of artificial intelligence,semantic communication has attracted great attention as a new communication ***,for IoT devices,however,processing image information efficiently in real time is an essential task for the rapid transmission of semantic *** the increase of model parameters in deep learning methods,the model inference time in sensor devices continues to *** contrast,the Pulse Coupled Neural Network(PCNN)has fewer parameters,making it more suitable for processing real-time scene tasks such as image segmentation,which lays the foundation for real-time,effective,and accurate image ***,the parameters of PCNN are determined by trial and error,which limits its *** overcome this limitation,an Improved Pulse Coupled Neural Networks(IPCNN)model is proposed in this *** IPCNN constructs the connection between the static properties of the input image and the dynamic properties of the neurons,and all its parameters are set adaptively,which avoids the inconvenience of manual setting in traditional methods and improves the adaptability of parameters to different types of *** segmentation results demonstrate the validity and efficiency of the proposed self-adaptive parameter setting method of IPCNN on the gray images and natural images from the matlab and Berkeley Segmentation *** IPCNN method achieves a better segmentation result without training,providing a new solution for the real-time transmission of image semantic information.

关键词： Internet of things(IoT) Semantic information Real-time application Improved pulse coupled neural network Image segmentation

Conservation genomics provides insights into genetic resilience and adaptation of the endangered Chinese hazelnut, Corylus chinensis

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Plant Diversity 2024年第3期46卷 294-308页

作者： zhen Yang Lisong Liang Weibo Xiang Lujun Wang Qinghua ma Zhaoshan Wang Key Laboratory of Tree Breeding and Cultivation National Forestry and Grassland AdministrationResearch Institute of ForestryChinese Academy of ForestryBeijing 100091China National Engineering Research Center of Eco-Environment Protection for Yangtze River Economic Belt China Three Gorges CorporationBeijing 100083China Rare Plants Research Institute of Yangtze River China Three Gorges CorporationYichang 443133China Research Institute of Economic Forest Cultivation and Processing Anhui Academy of ForestryHefei 230031China

Global climate change has increased concerns regarding biodiversity ***,many key conservation issues still required further research,including demographic history,deleterious mutation load,adaptive evolution,and putative *** we generated the first chromosome-level genome of the endangered Chinese hazelnut,Corylus chinensis,and compared the genomic signatures with its sympatric widespread ***-C yunnanensis *** found large genome rearrangements across all Corylus species and identified species-specific expanded gene families that may be involved in *** genomics revealed that both *** and the *** complex had diverged into two genetic lineages,forming a consistent pattern of southwestern-northern *** size of the narrow southwestern lineages of both species have decreased continuously since the late Miocene,whereas the widespread northern lineages have remained stable(***) or have even recovered from population bottlenecks(*** complex) during the *** with ***-C. yunnanensis complex,*** showed significantly lower genomic diversity and higher inbreeding ***,*** carried significantly fewer deleterious mutations than ***-C. yunnanensis complex,as more effective purging selection reduced the accumulation of homozygous *** also detected signals of positive selection and adaptive introgression in different lineages,which facilitated the accumulation of favorable variants and formation of local ***,both types of selection and exogenous introgression could have mitigated inbreeding and facilitated survival and persistence of ***,our study provides critical insights into lineage differentiation,local adaptation,and the potential for future recovery of endangered trees.

关键词： Conservation genomics Demographic history Inbreeding Genetic load Runs of homozygosity Local adaptation

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