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EFFECTS OF DIFFUSION WELDING PARAMETERS ON JOINT STRENGTH OF SiCw/6061AI COMPOSITE

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Acta Metallurgica Sinica(English Letters) 2000年第1期13卷 201-204页

作者： L.M. Liu J.T. Niu Z.H. Lai Y.L. guo and J.P. zhai (National Key Laboratory of Advanced Welding Production Technologyt HIT, Harbin 150001, China)

Diffusion welding was used to join SiCw/6061AI composites. The effects of welding pammeters on strength Of welded joint were investigated. JOint Of high quality for SiCw/6061Al composites can be obtained with aPPropri... 详细信息

关键词： diffusion welding SiCw/6061AI composite

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面向医疗大数据的风险自适应的访问控制模型

通信学报 2015年第12期36卷 190-199页

作者：惠榛李昊张敏冯登国中国科学院软件研究所北京100080

面对医疗大数据,策略制定者难以预测医生的访问需求,进而制定准确的访问控制策略。针对上述问题,提出一种基于风险的访问控制模型,能够适应性地调整医生的访问能力,保护患者隐私。该模型通过分析医生的访问历史,使用信息熵和EM算法量化... 详细信息

面对医疗大数据,策略制定者难以预测医生的访问需求,进而制定准确的访问控制策略。针对上述问题,提出一种基于风险的访问控制模型,能够适应性地调整医生的访问能力,保护患者隐私。该模型通过分析医生的访问历史,使用信息熵和EM算法量化医生侵犯隐私造成的风险。利用量化的风险,监测和控制对于医疗记录的过度访问以及特殊情况下的访问请求。实验结果表明,该模型是有效的,并且相比于其他模型能更为准确地进行访问控制。

关键词：风险访问控制大数据隐私自适应

Transcription factor HAND2 mutations in sporadic Chinese patients with congenital heart disease

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Chinese Medical Journal 2010年第13期123卷 1623-1627页

作者： SHEN Lei LI Xiao-feng SHEN A-dong WANG Qiang LIU Cai-xia guo Ya-jie SONG zhen-jiang LI Zhong-zhi Cardiac Centre Beijing Children's Hospital affiliated to Capital Medical University Beijing 100045 China Department of Orthopaedics Beijing Hospital Beijing 100730China

Background The basic helix-loop-helix transcription factor HAND2 plays an essential role in cardiac morphogenesis. However, the prevalence of HAND2 mutations in congenial heart disease （CHD） and the correlation between the HAND2 genotype and CHD phenotype have not been studied extensively. Methods We amplified the exons and the flanking intron sequences of the HAND2gene in 131 patients diagnosed with congenital defects of the right ventricle, outflow tract, aortic artery or cardiac cushion and confirmed the mutations by sequencing. Results Seven mutations including three missense mutations （P11R, S36N and V83L）, one isonymous mutation （H14H） and three mutations in untranslated region （241A〉G, 604C〉T and 3237T〉A） were identified in 12 out of the 131 patients. Both nonisonymous mutations are located in the transcriptional activation domain on the N-terminus. Only one mutation （S36N） was identified in 250 normal healthy controls. The distribution of 3637T〉A is the unique one which was different between the 2 groups. Conclusions HAND2 may be a potential candidate gene of stenosis of the right ventricle, outflow tract. Further study of those with a family history of HAND2 mutations will help convincingly relate their genotype to the pathogenesis of CHD.

关键词： bHLH HAND2 congenital heart disease transcription factor mutation

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新型抗抑郁药治疗焦虑谱系障碍研究进展

中国药学杂志 2007年第14期42卷 1041-1045页

作者：翟金国赵靖平中南大学湘雅二医院精神卫生研究所

目的介绍新型抗抑郁药治疗焦虑谱系障碍研究进展。方法在PubMed,Ovid,Springer,Proquest和Elsevier中搜索近期发表的有关文献,对有关资料进行分析。结果与结论抗抑郁药已经成为治疗焦虑谱系障碍的主要手段之一,新型抗抑郁药不但具有抗... 详细信息

目的介绍新型抗抑郁药治疗焦虑谱系障碍研究进展。方法在PubMed,Ovid,Springer,Proquest和Elsevier中搜索近期发表的有关文献,对有关资料进行分析。结果与结论抗抑郁药已经成为治疗焦虑谱系障碍的主要手段之一,新型抗抑郁药不但具有抗抑郁和抗焦虑双重药理作用,而且在治疗焦虑方面比传统抗抑郁药及苯二氮类抗焦虑药呈现出更多的优势。选择性5-HT再摄取抑制剂帕罗西汀、氟西汀、氟伏沙明、西酞普兰、艾司西酞普兰、舍曲林及选择性5-HT和NA再摄取抑制剂文拉法辛是治疗焦虑谱系障碍的一线药物,其他新型抗抑郁药如米氮平等治疗焦虑谱系障碍也有较好疗效。

关键词：焦虑谱系障碍抗抑郁药帕罗西汀氟西汀氟伏沙明西酞普兰艾司西酞普兰舍曲林文拉法辛

Modification of high-precision stable silver isotope analysis and implication on mineralization processes of noble Ag-Au ore deposits

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Modification of high-precision stable silver isotope analysi...

Safety and feasibility of transradial approach for primary percutaneous coronary intervention in elderly patients with acute myocardial infarction

2018年中国质谱学术大会（CMSC2018）

作者： guo Qi Wei Hai-zhen Jiang Shao-Yong Liu Xi Dong Ge State Key Laboratory for Mineral Deposits Research School of Earth Sciences and EngineeringNanjing University State Key Laboratory of Geological Processes and Mineral Resources Faculty of Earth ResourcesCollaborative Innovation Center for Exploration of Strategic Mineral ResourcesChinaUniversity of Geosciences

Except for extensive studies in core formation and volatile-element depletion processes using radiogenic Ag isotopes(i.e. the Pd-Ag chronometer), recent research has revealed that the mass fractionation of silver isotopes is in principle controlled by physico-chemical processes(e.g. evaporation, diffusion, chemical exchange etc.) during magmatic emplacement and hydrothermal alteration1. Because of minor variations of δ109 Ag in geologic processes, more accurate and precise measurements are required. In this work, a robust linear relationship between instrumental mass discrimination of Ag and Pd isotopes was obtained at the Ag/Pd molar ratio of 1:20. In Au-Ag oredeposits, silver minerals have complex paragenetic relationships with other minerals(e.g. chalcopyrite, sphalerite, galena, and pyrite etc.). Such abundant impurities make the complete separation of silver from matrices more complicated, which dramatically shifts the measured δ109 Ag values. The selection of alternative Pd isotope-pairs is effective in eliminating spectral matrix effects, so as to ensure accurate analysis under the largest possible ranges for metal impurities, which are Cu/Ag ≤ 50:1, Fe/Ag ≤ 600:1, Pb/Ag ≤ 10:1, Zn/Ag ≤ 1:1 respectively. With the modified procedure, we reported silver isotope compositions(δ109 Ag) in geological standard materials with external reproducibility of ± 0.009-± 0.084 ‰. A preliminary survey of δ109 Ag variations in minerals in four typical gold and silver deposits in the Chinese region show that the variation range of the silver isotope is much wider compared to that in rocks and chondrites. The silver isotopes in the Dazhuangzi gold deposit are near zero, and that in the other three types of skarn-type deposit, the Qixiashan lead zinc silver ore and the Zijinshan epithermal deposit are more positive compared with the bulk silicate earth(BSE), reflecting both the origins of ore metals and other potential controls(e.g. temperature, different host minerals) influence

关键词： Silver isotopes Instrumental mass discrimination Spectral matrix effects Ag-Au ore deposits

来源： cnki会议评论

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Chinese Medical Journal 2008年第9期121卷 782-786页

作者： YAN zhen-xian ZHOU Yu-jie ZHAO Ying-xin LIU Yu-yang SHI Dong-mei guo Yong-he CHENG Wan-jun Department of Cardiology Anzhen Hospital Capital Medical University Beijing 100029 China

Background Transradial coronary intervention has been widely used because of its effects in lowering the incidence of complications in vascular access site and improving patient satisfaction compared to the femoral approach. This study aimed to investigate the safety and feasibility of transradial approach for primary percutaneous coronary intervention （PCI） in elderly patients with acute myocardial infarction （AMI）. Methods A total of 103 consecutive elderly patients Cage 〉65 years） who were diagnosed as having AMI were indicated for PCI. Among them, 57 patients received primary PCI via the transradial approach （transradial intervention, TRI group）, and 46 underwent primary PCI via the transfemoral approach （transfemoral intervention, TFI group）. The success rate of puncture, puncture time, cannulation time, repeffusion time, the total time for PCI, the success rate of PCI, the use rates of temporary pacemaker and intra-aortic balloon pump （IABP）, and the total length of hospital stay of the patients in the two groups were compared. After the procedure, vascular access site complications and major adverse cardiovascular events （MACE） in the two groups in one month were observed. Results The success rates of puncture （98.2% vs 100.0%） and PCI （96.5% vs 95.7%） for the patients in the TRI and TFI groups were not statistically significant （P〉0.05）. The puncture time （（2.4±1.1） vs （2.0±0.9） minutes）, cannulation time （（2.7±0.5） vs （2.6±0.5） minutes）, reperfusion time （（16.2±4.5） vs （15.4±3.6） minutes）, total time of the procedure （（44.1±6.8） vs （41.2±5.7） minutes）, use rates of temporary pacemaker （1.8% vs 2.2%） and IABP （0 vs 2.2%） in the two groups were not statistically significant （P〉0.05）, but the hospital stay of the TFI group was longer than that of the TRI group （（10.1±4.6） vs （7.2±2..6） days, P〈0.01）. A radial occlusion was observed in the TRI group, but no ischemic syndrome in hand. In the TFI group, 4 patients had hematosis, 1 had pseudoaneurysm, and 1 had ma

关键词： transradial transfemoral percutaneous coronary intervention acute myocardial infarction elderly

制备条件对Ni/Al_2O_3催化剂催化乙醇水蒸气重整制氢性能的影响

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石油化工 2009年第11期38卷 1164-1168页

作者：翟彦青徐新郭芳林罗国华北京石油化工学院化学工程系北京102617

分别采用均匀沉淀法、沉淀法和浸渍法制备了Ni/Al_2O_3催化剂,在常压固定床反应器中评价了Ni/Al_2O_3催化剂在乙醇水蒸气重整制氢反应中的性能;采用X射线衍射和低温N_2物理吸附法对Al_2O_3载体和Ni/Al_2O_3催化剂进行了表征;考察了载体... 详细信息

分别采用均匀沉淀法、沉淀法和浸渍法制备了Ni/Al_2O_3催化剂,在常压固定床反应器中评价了Ni/Al_2O_3催化剂在乙醇水蒸气重整制氢反应中的性能;采用X射线衍射和低温N_2物理吸附法对Al_2O_3载体和Ni/Al_2O_3催化剂进行了表征;考察了载体焙烧温度及时间、催化剂制备方法、Ni负载量和催化剂还原时间等制备条件对Ni/Al_2O_3催化剂性能的影响。实验结果表明,以600℃下焙烧2 h的Al_2O_3为载体、采用浸渍法负载质量分数10.0%的Ni、在500℃焙烧1 h且在650℃下还原1 h的Ni/Al_2O_3催化剂的活性和选择性最好。在500℃、重时空速9 6 h^(-1)、水与乙醇的摩尔比为3:1的反应条件下,乙醇转化率达100%,产气速率为83.0 mL/min,H_2选择性为63.6%。

关键词：镍催化剂氧化铝载体乙醇水蒸气重整制氢

原位聚合法制备共聚POM/SiO_2纳米复合材料结构与性能表征

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高校化学工程学报 2008年第3期22卷 497-502页

作者：孙斓珲杨振国李小慧复旦大学材料科学系上海200433 上海材料研究所上海200437

以三聚甲醛和1,3-二氧戊环为单体,以氟化硼乙醚络合物为引发剂,用原位聚合方法制备共聚POM/SiO2纳米复合材料。使用FESEM和FT-IR研究纳米复合材料的微观形貌和组成,并且使用DSC及XRD等研究纳米复合材料的结晶行为。结果表明:纳米SiO2粒... 详细信息

以三聚甲醛和1,3-二氧戊环为单体,以氟化硼乙醚络合物为引发剂,用原位聚合方法制备共聚POM/SiO2纳米复合材料。使用FESEM和FT-IR研究纳米复合材料的微观形貌和组成,并且使用DSC及XRD等研究纳米复合材料的结晶行为。结果表明:纳米SiO2粒子在POM基体中分散均匀,且达到了纳米级的分散;纳米SiO2粒子的存在未影响共聚POM的分子链结构,POM高分子链与纳米SiO2表面的高能活性点发生了作用(例如氢键、配位键等),但并未发现化学作用的证据;共聚POM/SiO2纳米复合材料的熔点升高;部分纳米粒子充当了成核剂使结晶加快、球晶尺寸减小,还有部分纳米粒子的存在阻碍了片晶的生长,破坏了球晶的对称性。

关键词：共聚POM 纳米复合材料原位聚合法纳米SiO2 结晶性能

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中国综合农协的法律制度构造

河北学刊 2016年第1期36卷 177-180页

作者：柴振国田韶华河北经贸大学河北石家庄050061

兼具经济和社会功能的综合农协对促进农村经济社会发展具有积极作用,法律有必要对此种新型农村合作组织加以引导及规范。其在法律性质上属于公益法人,在组织形式上应当引进社会合作社这种独特的形式。此外,在会员、业务范围、资金来源... 详细信息

兼具经济和社会功能的综合农协对促进农村经济社会发展具有积极作用,法律有必要对此种新型农村合作组织加以引导及规范。其在法律性质上属于公益法人,在组织形式上应当引进社会合作社这种独特的形式。此外,在会员、业务范围、资金来源、治理结构,以及盈余分配和剩余财产的处理上均要围绕其宗旨进行相关的法律制度构造。

关键词：综合农协社区利益社会合作社