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Appendicitis combined with Meckel’s diverticulum obstruction, perforation, and inflammation in children: Three case reports

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World Journal of Clinical Cases 2024年第4期12卷 865-871页

作者： Yi-Meng Sun Wang Xin Yu-Fang liu zhe-Ming Guan Hao-Wen Du ning-ning Sun Yong-Dong liu School of Clinical Medicine Weifang Medical UniversityWeifang 261000Shandong ProvinceChina Department of Pediatric Surgery Weifang People’s HospitalWeifang 261000Shandong ProvinceChina Department of Burn Surgery Weifang People’s HospitalWeifang 261000Shandong ProvinceChina

BACKGROUND Meckel’s diverticulum is a common congenital malformation of the small intestine,with the three most common complications being obstruction,per-foration,and *** date,only a few cases have been reported *** children,the clinical symptoms are similar to *** most of the imaging features are nonspecific,the preoperative diagnosis is not *** addition,the clinical characteristics are highly similar to pediatric acute appendicitis,thus special attention is necessary to distinguish Meckel’s diver-ticulum from pediatric *** with poor disease control should undergo laparoscopic exploration to avoid serious complications,including intestinal necrosis,intestinal perforation and gastrointestinal *** SUMMARY This report presents three cases of appendicitis in children combined with intestinal obstruction,which was caused by fibrous bands(ligaments)arising from the top part of Meckel's diverticulum,diverticular perforation,and diver-ticular *** three patients,aged 11-12 years,had acute appendicitis as their initial clinical *** were treated by laparoscopic surgery with a favorable outcome.A complete dataset including clinical presentation,dia-gnostic imaging,surgical information,and histopathologic findings was also *** Preoperative diagnosis of Meckel’s diverticulum and its complications is challenging because its clinical signs and complications are similar to those of appendicitis in *** combined with laparotomy is useful for diagnosis and treatment.

关键词： Meckel’s diverticulum Complications Intestinal obstruction Perforation Appendicitis in children Mesodiverticular band Ligament Diverticular disease Case report

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Hyperspectral image super resolution using deep internal and self-supervised learning

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CAAI Transactions on Intelligence Technology 2024年第1期9卷 128-141页

作者： zhe liu Xian-Hua Han Graduate School of Science and Technology for Innovation Yamaguchi UniversityYamaguchiJapan Graduate School of Artificial Intelligence and Science Rikkyo UniversityTokyoJapan

By automatically learning the priors embedded in images with powerful modelling ca-pabilities,deep learning-based algorithms have recently made considerable progress in reconstructing the high-resolution hyperspectral(HR-HS)*** previously collected large-amount of external data,these methods are intuitively realised under the full supervision of the ground-truth ***,the database construction in merging the low-resolution(LR)HS(LR-HS)and HR multispectral(MS)or RGB image research paradigm,commonly named as HSI SR,requires collecting corresponding training triplets:HR-MS(RGB),LR-HS and HR-HS image simultaneously,and often faces dif-ficulties in *** learned models with the training datasets collected simultaneously under controlled conditions may significantly degrade the HSI super-resolved perfor-mance to the real images captured under diverse *** handle the above-mentioned limitations,the authors propose to leverage the deep internal and self-supervised learning to solve the HSI SR *** authors advocate that it is possible to train a specific CNN model at test time,called as deep internal learning(DIL),by on-line preparing the training triplet samples from the observed LR-HS/HR-MS(or RGB)images and the down-sampled LR-HS ***,the number of the training triplets extracted solely from the transformed data of the observation itself is extremely few particularly for the HSI SR tasks with large spatial upscale factors,which would result in limited reconstruction *** solve this problem,the authors further exploit deep self-supervised learning(DSL)by considering the observations as the unlabelled training ***,the degradation modules inside the network were elaborated to realise the spatial and spectral down-sampling procedures for transforming the generated HR-HS estimation to the high-resolution RGB/LR-HS approximation,and then the reconstruction errors of the observations were formulated for mea

关键词： computer vision deep learning deep neural networks hyperspectral image enhancement

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Influences of Graupel Microphysics on CMA-GFS Simulation of Summer Regional Precipitation

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Journal of Meteorological Research 2024年第1期38卷 27-38页

作者： zhe LI Qijun liu Zhanshan MA CMA Earth System Modeling and Prediction Centre China Meteorological Administration(CMA)Beijing 100081

The horizontal resolution of global numerical weather prediction models is continuously developing. However, due to the imperfect precipitation simulation/forecast of these models, the demand for considering riming particles in cloud microphysical schemes in these models is increasing. This study employed the latest versions of global atmospheric reanalysis data (ERA5), the satellite retrieval data of the Global Precipitation Observation Program (GPM),and station precipitation observations to explore the impacts of adding graupel to the cloud microphysical scheme in the China Meteorological Administration-Global Forecast System (CMA-GFS) on summer regional precipitation simulations in four Chinese climate zones. The results verify that the new graupel scheme can enable CMA-GFS to decently predict global graupel distribution, especially in tropical and midlatitude regions. The addition of graupel in the cloud microphysics increases the precipitation simulation in North China, while that in Southwest China is weakened and dispersed. Moreover, graupel scheme increases the precipitation simulations of almost all *** increase in light rain is obvious, and the absolute value of heavy rain is strengthened. This may be because graupel quickly melts into rain after falling out of the zero-temperature layer due to its large mass and fast falling speed, increasing surface precipitation. In summary, the addition of graupel in the cloud microphysical scheme can improve CMA-GFS’s underestimation of strong precipitation.

关键词： graupel cloud microphysical scheme precipitation China Meteorological Administration-Global Forecast System(CMA-GFS) climate zone

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Full lifetime demonstration of a Micro-Cathode-Arc thruster evolution characteristics

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Chinese Journal of Aeronautics 2024年第6期37卷 38-49页

作者： zhe ZHANG Zijing ZHAO Xiangyang liu ningfei WANG School of Aerospace Engineering Beijing Institute of TechnologyBeijing 100081China

Ground lifetime test is the most crucial experiment to assess the performance,*** flight qualification of electric propulsion,and it can bring new insights for understanding the operation *** work demonstrates a full lifetime test of 140000 cycles on a Micro-Cathode-Arc Thruster(μCAT)with 160μs charging time and 86 mJ charging energy.A four-probe resistivity measurement method is utilized to investigate variations in the conductive film thickness and resistivity throughout the thruster *** film parameters show that the lifetime of theμCAT can be divided into three *** the initial stage,the film thickness decreases by 1.2μm and the resistivity increases significantly due to the high discharge intensity and intense film ablation;In the steady stage,the change of the film thickness is within 5%,and the resistivity of the film increases slowly from 0.050Ω·mm to 0.223Ω·*** the end stage,the resistivity exponentially increases from 0.223Ω·mm to 1.176Ω·mm,with the increase accounting for 81%,ultimately resulting in the failure of the thruster open ***,the evolution of discharge parameters,and the variation of plume parameters are measured throughout the *** discharge characteristics also show significant differences in the duration of voltage and current in these three *** results of plume shape and plasma parameters are also well con-sistent with the discharge parameters and film *** results suggest that,for evaluating the steady stage lifetime of thrusters,the film thickness is the best indicator compared to the variations in resistivity and voltage-current *** the end stage,the plasma plume *** duration,and plume parameters can conveniently and clearly characterize the thruster failures and irregularity.

关键词： Electric propulsion Lifetime test Micro-Cathode-Arc Thruster(uCAT) Conductive film Discharge characteristics Plasma parameters

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Application status and prospect of ionic liquids in oilfield chemistry

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Petroleum 2024年第1期10卷 11-18页

作者： Jinsheng Sun Zhuoyang Xiu Li Li Kaihe Lv Xianfa Zhang Zonglun Wang Zhiwen Dai zhe Xu ning Huang Jingping liu School of Petroleum Engineering China University of Petroleum (East China) CNPC Engineering Technology R&D Company Limited Oil & Gas Technology Research Institute of Changqing Oilfield Company

The ionic liquid, as a new treatment agent, has been increasingly applied in oil fields due to its strong temperature resistance, good solubility and high surface activity. In this paper, we systematically discuss the action mechanism and application effect of ionic liquids in oilfield chemistry. Ionic liquids can inhibit shale hydration expansion and reduce fluid loss through adsorption and intercalation, inhibit the formation of natural gas hydrate through imidazole five-membered ring structure as a space barrier, reduce viscosity of heavy oil by breaking chemical bonds of heavy oil macromolecules and charge transfer,improve oil displacement efficiency by forming ions pairs with carboxyl groups in crude oil, demulsify by forming channels between dispersed water droplets, acidify the formation by reacting with water to produce acid, interacts with organic material through weak hydrogen bonds and extracts it from oilfield wastewater, desulphurize by inserting sulfide molecules into the “stack” structure and form liquid inclusion complex, inhibit corrosion by forming a protective film on the metal surface. Based on the above aspects, the development direction of ionic liquids is proposed. The application of ionic liquids in oilfield chemistry is still in its infancy. It is urgent to fully explore the application performance of ionic liquids in oilfield chemistry, which also provides theoretical and technical supports for efficient reservoir development.

关键词： Ionic liquids Oilfield chemistry Shale inhibitor Drilling fluid

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Inferring the Effects of Protein Variants on Protein-Protein Interactions with Interpretable Transformer Representations

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Research 2024年第2期2023卷 473-489页

作者： zhe liu Wei Qian Wenxiang Cai Weichen Song Weidi Wang Dhruba Tara Maharjan Wenhong Cheng Jue Chen Han Wang Dong Xu Guan ning Lin Shanghai Mental Health Center Shanghai Jiao Tong University School of MedicineSchool of Biomedical EngineeringShanghai Jiao Tong UniversityShanghaiChina Shanghai Key Laboratory of Psychotic Disorders ShanghaiChina School of Information Science and Technology Institute of Computational BiologyNortheast Normal UniversityChangchunChina Department of Electrical Engineering and Computer Science University of MissouriColumbiaMO 65211USA Christopher S.Bond Life Sciences Center University of MissouriColumbiaMO 65211USA

Identifying pathogenetic variants and inferring their impact on protein-protein interactions sheds light on their functional consequences on *** by the availability of experimental data on the consequences of protein interaction,most existing methods focus on building models to predict changes in protein binding ***,we introduced MIPPI,an end-to-end,interpretable transformer-based deep learning model that learns features directly from sequences by leveraging the interaction data from *** was specifically trained to determine the types of variant impact(increasing,decreasing,disrupting,and no effect)on protein-protein *** demonstrate the accuracy of MIPPI and provide interpretation through the analysis of learned attention weights,which exhibit correlations with the amino acids interacting with the ***,we showed the practicality of MIPPI in prioritizing de novo mutations associated with complex neurodevelopmental disorders and the potential to determine the pathogenic and driving ***,we experimentally validated the functional impact of several variants identified in patients with such ***,MIPPI emerges as a versatile,robust,and interpretable model,capable of effectively predicting mutation impacts on protein-protein interactions and facilitating the discovery of clinically actionable variants.

关键词： consequences weights versatile

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Homological dimensions of gentle algebras via geometric models

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Science China Mathematics 2024年第4期67卷 733-766页

作者： Yu-zhe liu Hanpeng Gao Zhaoyong Huang Department of Mathematics Nanjing UniversityNanjing 210093China School of Mathematical Sciences Anhui UniversityHefei 230601China

Let A=kQ/I be a finite-dimensional basic algebra over an algebraically closed field k,which is a gentle algebra with the marked ribbon surface(SA,MA,ΓA).It is known that SAcan be divided into some elementary polygons{Δi|1≤i≤d}byΓA,which has exactly one side in the boundary of ***■(Δi)be the number of sides ofΔibelonging toΓAif the unmarked boundary component of SAis not a side ofΔi;otherwise,■(Δi)=∞,and let f-Δbe the set of all the non-co-elementary polygons and FA(resp.f-FA)be the set of all the forbidden threads(*** finite length).Then we have(1)the global dimension of A is max1≤i≤d■(Δi)-1=maxΠ∈FAl(Π),where l(Π)is the length ofΠ;(2)the left and right self-injective dimensions of A are 0,if Q is either a point or an oriented cycle with full ***Δi∈f-Δ{1,■(Δi)-1}=max n∈f-F_(A)l(П),otherwise,As a consequence,we get that the finiteness of the global dimension of gentle algebras is invariant under AvellaGeiss(AG)-*** addition,we get that the number of indecomposable non-projective Gorenstein projective modules over gentle algebras is also invariant under AG-equivalence.

关键词： global dimension self-injective dimension gentle algebras marked ribbon surfaces geometric models AG-equivalence

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Development *** in limited urban sprawl:An integrated framework for resolving the urban boundary dilemma in China

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Journal of Geographical Sciences 2024年第7期34卷 1371-1393页

作者： SONG Xiangxiang ZHANG Zuo WANG zhe liu Yanzhong School of Public Administration Central China Normal UniversityWuhan430079China College of Resource and Environmental Engineering Wuhan University of Science and TechnologyWuhan430081China

The strategic delineation of the urban development boundary(UDB)is an effective initiative for efficient land resource allocation and for facilitating planned urban *** align with sustainable development objectives,UDB definitions have evolved to reconcile urban development with ecological *** study presents a UDB delineation framework from an integrated perspective that incorporates both demand-oriented and comprehensive ***,the urban construction land demand area was estimated based on population projections,meanwhile,the ecological red line(ERL)was delineated and integrated into the evaluation of the construction land ***,with the demand area as the simulation target and unsuitable areas as comprehensive constraints,the UDB was delineated by simulating future land use *** proposed framework was applied to Wuhan,a rapidly urbanizing city in central China,where the delineation of the UDB serves the dual purpose of managing the rapid expansion of built-up land and achieving a harmonious balance between urban development imperatives and ecological protection ***,based on the results and analysis,policy implications for the rational spatial planning of Wuhan were proposed,encompassing the spatial patterns and scientific decision-making in ecological conservation and urban *** results demonstrate that the efficacy of adopting a comprehensive perspective in delineating UDB effectively reconciles the competing needs of urban development and *** framework and the policy insights derived in this study could inform spatial planning efforts not only in Wuhan but also in other cities facing the dilemma of urban development and ecological protection.

关键词： urban development boundary(UDB) ecological red line(ERL) urban land suitability land use simulation integrated framework spatial decision-making

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Disease and Economic Burden of Kashin-Beck Disease—China,2021

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China CDC weekly 2024年第2期6卷 40-44页

作者： Silu Cui Wenjun Que zhe Jiao Qing Deng Xufeng Zhang Yanhong Cao ning liu Ailin Li Alphonse Sowanou zhe Li Tuo Wang Yang Li Jun Yu Junrui Pei NHC Key Laboratory of Etiology and Epidemiology(Harbin Medical University) Key Laboratory of Etiology and EpidemiologyEducation Bureau of Heilongjiang ProvinceInstitute of Kashin-Beck Disease ControlCenter for Endemic Disease ControlChinese Center for Disease Control and PreventionHarbin Medical UniversityHarbin CityHeilongjiang ProvinceChina NHC Key Laboratory of Etiology and Epidemiology(Harbin Medical University) Heilongjiang Provincial Key Laboratory of Trace Elements and Human HealthKey Laboratory of Etiology and EpidemiologyEducation Bureau of Heilongjiang ProvinceInstitute of Endemic Fluorosis ControlCenter for Endemic Disease ControlChinese Center for Disease Control and PreventionHarbin Medical UniversityHarbin CityHeilongjiang ProvinceChina

What is already known about this topic?Kashin-Beck disease(KBD)is a chronic and degenerative osteoarthropathy characterized by cartilage *** is an endemic disease that is highly prevalent among the Chinese population and poses a significant health *** is added by this report?This is the first national report on the economic burden of KBD in *** to the data from 2021,KBD has caused significant disease and economic *** most substantial reduction in healthy life expectancy was observed among patients with degree II severity and those aged 60 years and older,resulting in a total indirect economic burden of 112.74 million Chinese Yuan(CNY).What are the implications for public health practice?The results of this study will contribute to informing the development of tailored prevention and control strategies by the *** strategies will include targeted policies and recommendations for appropriate healthcare and financial subsidies,which will be based on the demographic characteristics of the endemic areas.

关键词： prevention degeneration burden

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PPB structure elimination,DRX nucleation mechanisms and grain growth behavior of the3rd-generation PM superalloy for manufacturing aviation components

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Chinese Journal of Aeronautics 2024年第1期37卷 325-344页

作者： Baoyun ZHANG Yongquan ning Zhaotian WANG Qiaomu liu School of Materials Science and Engineering Northwestern Polytechnical UniversityXi’an 710072China AECC Sichuan Gas Turbine Establishment Chengdu 610500China

Previous Particle Boundary(PPB),as the detrimental structure in Powder Metallurgy(PM)components,should be eliminated by subsequent hot process to improve the mechanical *** objective is to investigate the Dynamic Recrystallization(DRX)nucleation mechanisms and grain growth behavior of the 3rd-generation PM superalloy with PPB *** observation reveals that PPB decorated with(Ti,Ta,Nb)C carbides belongs to the discontinuous chain-like *** elimination of PPB networks can be achieved effectively via hot deformation due to the occurrence of *** different DRX nucleation mechanisms were proposed and discussed in detail according to the special microstructure characteristics of the PM ***,local lattice rotations can be detected in the vicinity of(Ti,Ta,Nb)C carbides during hot deformation and thus PPB structure serves as the preferential nucleation sites for DRX grains via Particle-Stimulated Nucleation(PSN).Then,Discontinuous-DRX(DDRX)characterized by grain boundary bulging dominates the microstructure refinement and Continuous-DRX(CDRX)operated by subgrain rotation can be regarded as an important assistant *** last,the initial Σ3 boundaries would lose their twin characteristics owing to the crystal rotation and then transform into the general High Angle Grain Boundaries(HAGBs).The distorted twins provide additional DRX nucleation sites,viz.,twin-assisted *** attention was focused on the grain growth behavior of the PM superalloy in subsequent annealing *** recrystallization temperature was determined to be about 1110.C and 1140.C can be considered as the critical temperature for grain *** findings would provide theoretical support for microstructure refinement of the 3rd-generation PM superalloy,which is of pivotal significance for improving the mechanical properties of aviation components.

关键词： PM superalloy Previous Particle Boundary(PPB) DRX nucleation Grain growth Microstructure refinement

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