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Surgical resection and neoadjuvant therapy in patients with gastric cancer and ovarian metastasis: A real-world study

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2426-2435页

作者： Hui-Ping Yan Hong-Rui Lu Yu-Xia Zhang Liu Yang zhe-ling chen School of Public Health Hangzhou Medical CollegeHangzhou 310000Zhejiang ProvinceChina Cancer Center Department of Medical OncologyZhejiang Provincial People’s Hospital(Affiliated People’s Hospital)Hangzhou 310000Zhejiang ProvinceChina Affiliated Bijie Hospital Zhejiang Provincial People’s HospitalBijie 551700Guizhou ProvinceChina

BACKGROUND Regarding when to treat gastric cancer and ovarian metastasis(GCOM)and whether to have metastatic resection surgery,there is presently debate on a global *** purpose of this research is to examine,in real-world patients with GCOM,the survival rates and efficacy of metastatic vs non-metastasized *** To investigate the survival time and efficacy of metastatic surgery and neoadjuvant therapy in patients with *** This study retrospectively analyzed the data of 41 GCOM patients admitted to zhejiang Provincial People’s Hospital from June 2009 to July *** diagnosis of all patients was confirmed by *** primary study endpoints included overall survival(OS),ovarian survival,OS after surgery(OSAS),disease-free survival(DFS),differences in *** This study had 41 patients in *** surgical group(n=27)exhibited significantly longer median OS(mOS)and median overall months(mOM)compared to the nonoperative group(n=14)(mOS:23.0 vs 6.9 months,P=0.015;mOM:18.3 vs 3.8 months,P=0.001).However,there were no significant differences observed in mOS,mOM,median OSAS(mOSAS),and median DFS(mDFS)between patients in the surgical resection plus neoadjuvant therapy group(n=11)and those who surgical resection without neoadjuvant therapy group(n=16)(mOS:26.1 months vs 21.8 months,P=0.189;mOM:19.8 vs 15.2 months,P=0.424;mOSAS:13.9 vs 8.7 months,P=0.661,mDFS:5.1 vs 8.2 months,P=0.589).CONCLUSION Compared to the non-surgical group,the surgical group’s survival duration and efficacy are noticeably *** efficacy and survival time of the direct surgery group and the neoadjuvant therapy group did not differ significantly.

关键词： Gastric cancer Prognosis Ovarian metastasis Neoadjuvant therapy Surgery

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Investigating effect of coke porosity on blast furnace performance based on multi-physical fields

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Journal of Iron and Steel Research International 2024年第2期31卷 357-367页

作者： Ji chen Zhao Lei zhe Yao Li Wang Qiang ling Ping Cui Anhui Province Key Laboratory of Coal Clean Conversion and High Valued Utilization School of Chemistry and Chemical EngineeringAnhui University of TechnologyMa’anshan243002AnhuiChina Shanxi Academy of Printing Technology Research Institute Co. Ltd.Xi’an710077ShaanxiChina

Reducing coke use is an effective measure to reduce carbon emission and energy consumption in the blast furnace(BF)***,BF is a high-temperature moving bed reactor,where complex physical transformations coupled with complicated reactions *** makes it challenging to investigate the factors determining BF performance with the conventional method.A multi-physical field coupling mathematical model of BF was thus developed to describe its mass and heat transfer as well as its intrinsic ***,the proposed model was validated with the production *** coupling conditions,influences of dominating reactions on BF performance(temperature distribution,gas distribution,iron formation reaction,and direct reduction degree)were *** results indicated that coke combustion,indirect reduction,and direct reduction of iron ore mainly took place nearby the shaft tuyere,cohesive zone,and dripping zone,***,the rate of coke solution loss reaction was increased with the rising coke porosity in the cohesive *** the effect of coke porosity on the efficiency and stability of BF,the coke porosity of 0.42 was regarded as a reasonable value.

关键词： Blast furnace Mathematical model Multi-physical field Simulation Coke porosity

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Nanodiamond/Ti_(3)C_(2) MXene-coated quartz crystal microbalance humidity sensor with high sensitivity and high quality factor

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Rare Metals 2024年第6期43卷 2719-2729页

作者： Yao Yao Qiao chen Yan-Qi Li Xian-He Huang Wei-Wei ling zhe-MiaoXie Jia-QiWang Chang-Ming chen College of Communication Engineering Chengdu University of Information TechnologyChengdu 610225China School of Automation Chongqing University of Posts and TelecommunicationsChongqing 400065China School of Automation Engineering University of Electronic Science and Technology of ChinaChengdu 611731China Advanced Micro-/Nano-Devices Lab Department of Systems Design EngineeringUniversity of WaterlooWaterlooON N2L 3GlCanada

To address the challenge of achieving both high sensitivity and a high quality factor in quartz crystal microbalance(QCM)humidity sensors,a nanodiamond(ND)/Ti_(3)C_(2)MXene composite-coated QCM humidity sensor was *** material characteristics of ND,Ti_(3)C_(2)MXene,and ND/Ti_(3)C_(2)MXene composite were analyzed by transmission electron microscopy(TEM)and Fourier transform infrared(FTIR)*** experimental results demonstrated that the hydrophilic ND nanoparticles coated on Ti_(3)C_(2) MXene nanosheet prevented the self-stacking of Ti_(3)C_(2)MXene and enhanced the sensitivity of Ti_(3)C_(2) MXene-based QCM humidity ***,the high mechanical modulus of Ti_(3)C_(2) MXene material helped ND/Ti_(3)C_(2)MXene composite-coated QCM humidity sensor to achieve a high quality factor(>20,000).ND/Ti_(3)C_(2)MXene compositecoated QCM humidity sensor exhibited a sensitivity of 82.45 Hz/%RH,a humidity hysteresis of 1.1%RH,fast response/recovery times,acceptable repeatability,and good stability from 11.3%RH to 97.3%*** response mechanism of ND/Ti_(3)C_(2) MXene composite-coated QCM humidity sensor was analyzed in combination with a bi-exponential kinetic adsorption ***,the potential application of ND/Ti_(3)C_(2)MXene composite-coated QCM humidity sensor was demonstrated through its frequency response to wooden blocks with different moisture contents.

关键词： Humidity sensor Quartz crystal microbalance Nanodiamond Ti_(3)C_(2)MXene High quality factor

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Influence of heat treatment on microstructure,mechanical and corrosion behavior of WE43 alloy fabricated by laser-beam powder bed fusion

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International Journal of Extreme Manufacturing 2024年第1期6卷 258-275页

作者： chenrong ling Qiang Li zhe Zhang Youwen Yang Wenhao Zhou Wenlong chen Zhi Dong Chunrong Pan Cijun Shuai College of Mechanical and Electrical Engineering Jiangxi University of Science and TechnologyGanzhou 341000People’s Republic of China School of Mechanical and Electronic Engineering Suzhou UniversitySuzhou 234000People’s Republic of China Shaanxi Key Laboratory of Biomedical Metal Materials Northwest Institute for Non-ferrous Metal ResearchXi’an 710016People’s Republic of China Department of Orthopedics First Afffliated Hospital of Gannan Medical CollegeGanzhou 341000People’s Republic of China School of Mechanical and Automotive Engineering South China university of technologyGuangzhou 510641People’s Republic of China State Key Laboratory of High-Performance Complex Manufacturing Central South UniversityChangsha 410083People’s Republic of China Double Medical Technology Inc. Xiamen 361026People’s Republic of China

Magnesium(Mg)alloys are considered to be a new generation of revolutionary medical ***-beam powder bed fusion(PBF-LB)is suitable for fabricating metal implants withpersonalized and complicated ***,the as-built part usually exhibits undesirable microstructure and unsatisfactory *** this work,WE43 parts were firstly fabricated by PBF-LB and then subjected to heat *** a high densification rate of 99.91%was achieved using suitable processes,the as-built parts exhibited anisotropic and layeredmicrostructure with heterogeneously precipitated Nd-rich *** heat treatment,fine and nano-scaled Mg24Y5particles were ***,theα-Mg grainsunderwent recrystallization and turned coarsened slightly,which effectively weakened thetexture intensity and reduced the *** a consequence,the yield strength and ultimate tensile strength were significantly improved to(250.2±3.5)MPa and(312±3.7)MPa,respectively,while the elongation was still maintained at a high level of 15.2%.Furthermore,the homogenized microstructure reduced the tendency of localized corrosion and favoredthe development of uniform passivation ***,the degradation rate of WE43 parts was decreased by an order of ***,in-vitro cell experiments proved their favorable biocompatibility.

关键词： laser-beam powder bed fusion WE43 alloys heat treatment mechanical performance biodegradation behavior

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Aircraft parameter estimation using a stacked long short-term memory network and Levenberg-Marquardt method

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Chinese Journal of Aeronautics 2024年第2期37卷 123-136页

作者： zhe HUI Yinan KONG Weigang YAO Gang chen School of Aerospace Science and Technology Xidian UniversityXi’an 710071China Computation Aerodynamics Institution China Aerodynamics Research and Development CenterMianyang 621000China Faculty of Computing Engineering and MediaDe Montfort UniversityLeicester LE19BHUnited Kingdom School of Aerospace Engineering Xi’an Jiaotong UniversityXi’an 710049China

To effectively estimate the unknown aerodynamic parameters from the aircraft’s flight data,this paper proposes a novel aerodynamic parameter estimation method incorporating a stacked Long Short-Term Memory(LSTM)network model and the Levenberg-Marquardt(LM)*** stacked LSTM network model was designed to realize the aircraft dynamics modeling by utilizing a frame of nonlinear functional mapping based entirely on the measured input-output data of the aircraft system without requiring explicit postulation of the *** LM method combines the already-trained LSTM network model to optimize the unknown aerodynamic *** proposed method is applied by using the real flight data,generated by ATTAS aircraft and a bio-inspired morphing Unmanned Aerial Vehicle(UAV).The investigation reveals that for the two different flight data,the designed stacked LSTM network structure can maintain the efficacy of the network prediction capability only by appropriately adjusting the dropout rates of its hidden layers without changing other network parameters(i.e.,the initial weights,initial biases,number of hidden cells,time-steps,learning rate,and number of training iterations).Besides,the proposed method’s effectiveness and potential are demonstrated by comparing the estimated results of the ATTAS aircraft or the bio-inspired morphing UAV with the corresponding reference values or wind-tunnel results.

关键词： Parameter estimation LSTM network model LM method Aerodynamic parameters Flight data Aircraft dynamics modeling Network prediction capability Network parameters

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QoE oriented intelligent online learning evaluation technology in B5G scenario

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Digital Communications and Networks 2024年第1期10卷 7-15页

作者： Mingzi chen Xin Wei Peizhong Xie zhe Zhang School of Communications and Information Engineering Nanjing University of Posts and TelecommunicationsNanjing210003China Key Lab of Broadband Wireless Communication and Sensor Network Technology(Nanjing University of Posts and Telecommunications) Ministry of EducationNanjing210003China Institute of Higher Education Nanjing University of Posts and TelecommunicationsNanjing210003China

Students'demand for online learning has exploded during the post-COvID-19 pandemic ***,due to their poor learning experience,students'dropout rate and learning performance of online learning are not always *** technical advantages of Beyond Fifth Generation(B5G)can guarantee a good multimedia Quality of Experience(QoE).As a special case of multimedia services,online learning takes into account both the usability of the service and the cognitive development of the *** that affect the Quality of Online Learning Experience(OL-QoE)become more *** get over this dilemma,we propose a systematic scheme by integrating big data,Machine Learning(ML)technologies,and educational psychology ***,we first formulate a general definition of OL-QoE by data analysis and experimental *** formula considers both the subjective and objective factors(i.e.,video watching ratio and test scores)that most affect ***,we induce an extended layer to the classic Broad Learning System(BLS)to construct an Extended Broad Learning System(EBLS)for the students'OL-QoE *** the extended layer can increase the width of the BLS model and reduce the redundant nodes of BLS,the proposed EBLS can achieve a trade-off between the prediction accuracy and computation ***,we provide a series of early intervention suggestions for different types of students according to their predicted OL-QoE *** timely interventions,their OL-QoE and learning performance can be *** results verify the effectiveness oftheproposed scheme.

关键词： B5G Online learning Quality of experience

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Micro defects formation and dynamic response analysis of steel plate of quasi-cracking area subjected to explosive load

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Defence Technology（防务技术） 2024年第1期31卷 580-593页

作者： zheng-qing Zhou Ze-chen Du Xiao Wang Hui-ling Jiang Qiang Zhou Yu-long Zhang Yu-zhe Liu Pei-ze Zhang Research Institute of Macro-Safety Science University of Science and TechnologyBeijing100083China School of Civil and Resource Engineering University of Science and Technology BeijingBeijing100083China School of Mechanical Engineering Nantong UniversityNantong226019China China North Industry Advanced Technology Generalization Institute Beijing100089China China Academy of Ordnance Science China

As the protective component,steel plate had attracted extensive attention because of frequently threats of explosive *** this paper,the evolution of microstructure and the mechanism of damage in the quasi-cracking area of steel plate subjected to explosive load were discussed and the relationships between micro defects and dynamic mechanical response were *** the explosion experiment,five observation points were selected equidistant from the quasi-cracking area of the section of the steel plate along the thickness direction,and the characteristics of micro defects at the observation points were analyzed by optical microscope(OM),scanning electron microscope(SEM) and electron backscattered diffraction(EBSD).The observation result shows that many slip bands(SBs) appeared,and the grain orientation changed obviously in the steel plate,the two were the main damage types of micro *** addition,cracks,peeling pits,grooves and other lager micro defects were appeared in the lower area of the *** stress parameters of the observation points were obtained through an effective numerical *** mechanism of damage generation and crack propagation in the quasicracking area were clarified by comparing the specific impulse of each observation point with the corresponding micro *** result shows that the generation and expansion of micro defects are related to the stress area(*** upper compression area,the neutral plane area,and the lower tension area).The micro defects gather and expand at the grain boundary,and will become macroscopic damage under the continuous action of tensile ***,the micro defects at the midpoint of the section of the steel plate in the direction away from the explosion center(*** horizontal direction) were also *** was found that the specific impulse at these positions were much smaller than that in the thickness direction,the micro defects were only SBs and a few micro cracks,and the those decrea

关键词： Explosive load Quasi-cracking area Micro defects Steel plate Dynamic response Numerical simulation

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Evaluation of 3D crustal seismic velocity models in southwest China:Model performance,limitation,and prospects

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Science China Earth Sciences 2024年第2期67卷 604-619页

作者： Xin WANG ling chen Qi-Fu chen Key Laboratory of Earth and Planetary Physics Institute of Geology and GeophysicsChinese Academy of SciencesBeijing100029China College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijing100049China State Key Laboratory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of SciencesBeijing100029China

Southwest China is a tectonically and seismically active region,witnessing strong deformation due to the collision between the Indian and Eurasian *** the subsurface velocity structure of this region is thus important in understanding the tectonics and geodynamic processes of continental collision and in mitigating seismic *** studies have provided various 3D seismic velocity models in southwest ***,discrepancies exist among these models,and less effort has been made to quantify the reliability and accuracy of these existing velocity *** this study,we use regional 3D waveform simulation to evaluate the performance of various regional crustal 3D velocity models in reproducing observed *** particularly focus on two recent earthquake sequence in the region,the 2021 Yunnan Yangbi MS_(6.4) earthquake sequence and the 2022 Sichuan Luding MS_(6.8) earthquake *** tested 3D velocity models include the Southwest China Community Velocity model V1.0,the Unified Seismic Tomography Models for Continental China Lithosphere V2.0,the adjoint full waveform tomography model of the crustal and upper mantle beneath Eastern Tibetan Plateau,and the shallow seismic structure model beneath continental *** results show that the tested 3D velocity models generally capture well long-period(<0.2 Hz)waveforms,indicating that the 3D models adequately resolve overall large-scale subsurface ***,the 3D synthetics show discrepancies in higher frequencies(0.05–0.3 Hz)and the performance of the 3D velocity models varies from region to region,suggesting that smaller scale heterogeneities are not well *** shallow velocity structures(<10 km)can improve the waveform fitting,emphasizing the importance of incorporating shallow structures in waveform *** full-waveform tomography model shows a slighter better performance than the other models,especially for the body-waves,highlighting the advantages

关键词： Southwest China Seismic tomography models Shallow Structures Waveform simulation Model evaluation

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Lewis Base Catalyzed Selenofunctionalization of Alkynes with Acid-Controlled Divergent Chemoselectivity

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Chinese Journal of Chemistry 2024年第14期42卷 1623-1629页

作者： ling-ling chen Ren-Fei Cao Hua Ke Zhi-Min chen School of Chemistry and Chemical Engineering Shanghai Key Laboratory for Molecular Engineering of Chiral DrugsShanghai Jiao Tong UniversityShanghai200240 China Engineering Technology Research Center for Environmental Protection Materials Pingxiang UniversityPingxiangJiangxi337055 China

Lewis base catalyzed and Brønsted acid controlled chemodivergent electrophilic selenofunctionalizations of alkynes were developed for the first *** selenium-containing tetrasubstituted alkenes were readily obtained in moderate to excellent yields with complete E/Z *** the substrates were 1-ethynyl naphthol derivatives,linear selenium-containing tetrasubstituted alkenes were produced via intermolecular oxygen nucleophilic attack in the absence of acid additive;in contrast,cyclic selenium-containing tetrasubstituted alkenes were generated through intramolecular carbon nucleophilic capture with the addition of Brønsted acid.

关键词： Alkynes Electrophilic addition Chemoselectivity Lewis base catalysis Selenofunctionalization

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A credibility-aware swarm-federated deep learning framework in internet of vehicles

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Digital Communications and Networks 2024年第1期10卷 150-157页

作者： zhe Wang Xinhang Li Tianhao Wu chen Xu Lin Zhang School of Artificial Intelligence Beijing University of Posts and TelecommunicationsBeijing100876China

Although Federated Deep Learning(FDL)enables distributed machine learning in the Internet of Vehicles(IoV),it requires multiple clients to upload model parameters,thus still existing unavoidable communication overhead and data privacy *** recently proposed Swarm Learning(SL)provides a decentralized machine learning approach for unit edge computing and blockchain-based coordination.A Swarm-Federated Deep Learning framework in the IoV system(IoV-SFDL)that integrates SL into the FDL framework is proposed in this *** IoV-SFDL organizes vehicles to generate local SL models with adjacent vehicles based on the blockchain empowered SL,then aggregates the global FDL model among different SL groups with a credibility weights prediction *** experimental results show that compared with the baseline frameworks,the proposed IoV-SFDL framework reduces the overhead of client-to-server communication by 16.72%,while the model performance improves by about 5.02%for the same training iterations.

关键词： Swarm learning Federated deep learning Internet of vehicles Privacy Efficiency

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