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Social insights on the implementation of One Health in zoonosis prevention and control: a scoping review

Infectious Diseases of Poverty 2022年第3期11卷 1-11页

作者： Junyi He zhaoyu guo Pin Yang Chunli Cao Jing Xu Xiaonong Zhou Shizhu Li National Institute of Parasitic Diseases Chinese Center for Disease Control and Prevention(Chinese Center for Tropical Diseases Research)NHC Key Laboratory of Parasite and Vector BiologyWHO Collaborating Centre for Tropical DiseasesNational Center for International Research on Tropical DiseasesShanghai200025China School of Global Health Chinese Center for Tropical Diseases ResearchShanghai Jiao Tong University School of MedicineShanghai200025China

Background:The One Health (OH) concept has been promoted widely around the globe. OH framework is expected to be applied as an integrated approach to support addressing zoonotic diseases as a significant global health issue and to improve the efficiency and effectiveness of zoonosis prevention and control. This review is intended to overview the social impact of the implementation of OH on zoonosis prevention and control.Methods:A scoping review of studies in the past 10 years was performed to overview the integration feature of OH in zoonosis prevention and control and the social impacts of OH. PubMed and Web of Science were searched for studies published in English between January 2011 and June 2021. The included studies were selected based on predefined criteria.Results:Thirty-two studies were included in this review, and most of them adopted qualitative and semi-qualitative methods. More than 50% of the studies focused on zoonosis prevention and control. Most studies were conducted in low- and middle-income countries in Africa and Asia. Applying OH approach in diseases control integrates policymakers, stakeholders, and academics from various backgrounds. The impact of OH on economic is estimated that it may alleviate the burden of diseases and poverty in the long term, even though more financial support might be needed at the initial stage of OH implementation. OH implementation considers social and ecological factors related to zoonosis transmission and provides comprehensive strategies to assess and address related risks in different communities according to regions and customs.Conclusions:Based on reviewed literature, although there seems to be a lack of guidelines for assessing and visualizing the outcomes of OH implementation, which may limit the large-scale adoption of it, evidence on the contributions of implementing OH concepts on zoonosis prevention and control indicates long-term benefits to society, including a better integration of politics, stakeholders and academics to improve their cooperation,

关键词： One Health Zoonotic diseases Social impacts Social perspectives

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Assessment of the Health-Related Quality of Life in Neurocysticercosis Patients in Hot Spot Areas—China,2017–2018

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China CDC weekly 2022年第28期4卷 618-621,I0005页

作者： Yingjun Qian Xinzhong Zang Huanzhang Li zhaoyu guo Changhai Zhou Menbao Qian Yingdan Chen Hongkun Liu Yuhua Liu Shizhu Li National Institute of Parasitic Diseases Chinese Center for Disease Control and Prevention(Chinese Center for Tropical Diseases Research)NHC Key Laboratory of Parasite and Vector BiologyWHO Collaborating Centre for Tropical DiseasesShanghaiChina Qilu Hospital Cheeloo College of MedicineShandong UniversityQingdao CityShandong ProvinceChina Dandong City Center for Disease Control and Prevention Dandong CityLiaoning ProvinceChina Dali Prefectural Institute of Research and Control on Schistosomiasis Dali CityYunnan ProvinceChina

Summary What is already known about this topic?Neurocysticercosis is the most severe form of infection caused by ingesting cysticerci,the larval cysts of the pork tapeworm,Taenia solium.Approximately 50 million people worldwide have neurocysticercosis,which is the leading cause of acquired epilepsy in many endemic countries.What is added by this report?The health of neurocysticercosis patients can be seriously impaired,including through loss of mobility,inability to do self-care,impairment of usual activities,pain/discomfort,anxiety/depression,and impaired cognition.Cognitive impairment is the major consequence of neurocysticercosis and significant contributor to decreased health-related quality of life.Our study made the first estimate of disability weight from neurocysticercosis as a key parameter for disease burden assessment in China.What are the implications for public health practice?To prevent severe health outcomes from neurocysticercosis in China,it is necessary to improve public awareness of neurocysticercosis and relevant health behaviors.

关键词： impaired cysticercosis epilepsy

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Spatiotemporal heterogeneity of schistosomiasis in China's Mainland:Evidence from a multi-stage continuous downscaling sentinel monitoring

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Asian Pacific Journal of Tropical Medicine 2022年第1期15卷 26-34页

作者： Yanfeng Gong Jiaxin Feng Zhuowei Luo Jingbo Xue zhaoyu guo Lijuan Zhang Shang Xia Shan Lv Jing Xu Shizhu Li National Institute of Parasitic Diseases Chinese Center for Disease Control and PreventionShanghai 200025China Chinese Center for Tropical Diseases Research Shanghai 200025China NHC Key Laboratory of Parasite and Vector Biology Shanghai 200025China WHO Collaborating Centre for Tropical Diseases Shanghai 200025China National Center for International Research on Tropical Diseases Shanghai 200025China School of Global Health Chinese Center for Tropical Diseases ResearchShanghai Jiao Tong University School of MedicineShanghai 200025China

Objective:To determine the spatiotemporal distribution of Schistosoma(S.)japonicum infections in humans,livestock,and Oncomelania(O.)hupensis across the endemic foci of China.Methods:Based on multi-stage continuous downscaling of sentinel monitoring,county-based schistosomiasis surveillance data were captured from the national schistosomiasis surveillance sites of China from 2005 to 2019.The data included S.japonicum infections in humans,livestock,and O.hupensis.The spatiotemporal trends for schistosomiasis were detected using a Joinpoint regression model,with a standard deviational ellipse(SDE)tool,which determined the central tendency and dispersion in the spatial distribution of schistosomiasis.Further,more spatiotemporal clusters of S.japonicum infections in humans,livestock,and O.hupensis were evaluated by the Poisson model.Results:The prevalence of S.japonicum human infections decreased from 2.06%to zero based on data of the national schistosomiasis surveillance sites of China from 2005 to 2019,with a reduction from 9.42%to zero for the prevalence of S.japonicum infections in livestock,and from 0.26%to zero for the prevalence of S.japonicum infections in O.hupensis.Analysis using an SDE tool showed that schistosomiasis-affected regions were reduced yearly from 2005 to 2014 in the endemic provinces of Hunan,Hubei,Jiangxi,and Anhui,as well as in the Poyang and Dongting Lake regions.Poisson model revealed 11 clusters of S.japonicum human infections,six clusters of S.japonicum infections in livestock,and nine clusters of S.japonicum infections in O.hupensis.The clusters of human infection were highly consistent with clusters of S.japonicum infections in livestock and O.hupensis.They were in the 5 provinces of Hunan,Hubei,Jiangxi,Anhui,and Jiangsu,as well as along the middle and lower reaches of the Yangtze River.Humans,livestock,and O.hupensis infections with S.japonicum were mainly concentrated in the north of the Hunan Province,south of the Hubei Province,north of the Jiangxi Province,and southwestern portion

关键词： Schistosomiasis Sentinel surveillance Spatiotemporal heterogeneity China

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Establishment of an indicator framework for global One Health Intrinsic Drivers index based on the grounded theory and fuzzy analytical hierarchy-entropy weight method

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Infectious Diseases of Poverty 2022年第6期11卷 97-98页

作者： Jiaxin Feng zhaoyu guo Lin Ai Jingshu Liu Xiaoxi Zhang Chunli Cao Jing Xu Shang Xia Xiao‑Nong Zhou Jin Chen Shizhu Li National Institute of Parasitic Diseases Chinese Center for Disease Control and Prevention(Chinese Center for Tropical Diseases Research)NHC Key Laboratory of Parasite and Vector BiologyWHO Collaborating Centre 不详

Background:One Health has become a global consensus to deal with complex health problems.However,the pro‑gress of One Health implementation in many countries is still relatively slow,and there is a lack of systematic evalua‑tion index.The purpose of this study was to establish an indicator framework for global One Health Intrinsic Drivers index(GOH-IDI)to evaluate human,animal and environmental health development process globally.Method:First,82 studies were deeply analyzed by a grounded theory(GT)method,including open coding,axial coding,and selective coding,to establish a three-level indicator framework,which was composed of three selective codes,19 axial codes,and 79 open codes.Then,through semi-structured interviews with 28 health-related experts,the indicators were further integrated and simplifed according to the inclusion criteria of the indicators.Finally,the fuzzy analytical hierarchy process combined with the entropy weight method was used to assign weights to the indi‑cators,thus,forming the evaluation indicator framework of human,animal and environmental health development process.Results:An indicator framework for GOH-IDI was formed consisting of three selective codes,15 axial codes and 61 open codes.There were six axial codes for“Human Health”,of which“Infectious Diseases”had the highest weight(19.76%)and“Injuries and Violence”had the lowest weight(11.72%).There were four axial codes for“Animal Health”,of which“Animal Epidemic Disease”had the highest weight(39.28%)and“Animal Nutritional Status”had the low‑est weight(11.59%).Five axial codes were set under“Environmental Health”,among which,“Air Quality and Climate Change”had the highest weight(22.63%)and“Hazardous Chemicals”had the lowest weight(17.82%).Conclusions:An indicator framework for GOH-IDI was established in this study.The framework were universal,balanced,and scientifc,which hopefully to be a tool for evaluation of the joint development of human,animal and environmental health in diferent regions globally.

关键词： Global One Health Intrinsic drivers index Indicator Grounded theory Fuzzy analytical hierarchy process Entropy weight method

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Pollution characteristics of peroxyacetyl nitrate in karst areas in Southwest China

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Atmospheric and Oceanic Science Letters 2024年第2期17卷 27-32页

作者： Songjun guo Xu Wei Hongjiao Li Wen Qin Yijun Mu Jiongli Huang Chuan Nong Junchao Yang Dabiao Zhang Hua Lin Jingying Mao zhaoyu Mo College of Resources Environment and MaterialsGuangxi UniversityNanningGuangxiChina Scientific Research Academy of Guangxi Environmental Protection NanningGuangxiChina

桂林是世界著名的地处喀斯特地区的旅游胜地,其光化学污染问题日益严重,过氧乙酰硝酸酯(PAN)被认为是光化学污染的可靠指标,也是本研究的重点.本研究于2021年10月首次观测了桂林的PAN的浓度为0.087-2.559ppb,同时探讨了PAN典型高值过程... 详细信息

桂林是世界著名的地处喀斯特地区的旅游胜地,其光化学污染问题日益严重,过氧乙酰硝酸酯(PAN)被认为是光化学污染的可靠指标,也是本研究的重点.本研究于2021年10月首次观测了桂林的PAN的浓度为0.087-2.559ppb,同时探讨了PAN典型高值过程的成因.此次污染主要来源于东北方向污染气团的水平和高空输送,同时,高温,强辐射和低湿度等气象条件也促进了本地PAN的形成.本研究同时估算了桂林市的O3背景浓度为20.347ppb.这项研究为城市的光化学污染控制工作提供了理论基础。

关键词：过氧乙酰硝酸酯光化学反应传输影响气象因素

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移动边缘网络中的多目标缓存优化方法

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小型微型计算机系统 2024年第4期45卷 894-901页

作者：吴越薛钊煜郭婉婉崔志华太原科技大学计算机科学与技术学院太原030024

随着5G时代的到来,各类移动应用蓬勃发展,用户量快速增长,大量的通信流量对移动边缘网络造成了巨大的压力,缓存资源紧张的问题逐渐凸显.为此,本文提出了一种基于多目标优化算法的移动边缘网络缓存放置策略,考虑包含一个宏基站和若干小... 详细信息

随着5G时代的到来,各类移动应用蓬勃发展,用户量快速增长,大量的通信流量对移动边缘网络造成了巨大的压力,缓存资源紧张的问题逐渐凸显.为此,本文提出了一种基于多目标优化算法的移动边缘网络缓存放置策略,考虑包含一个宏基站和若干小基站的边缘网络,通过分析边缘网络缓存中不同利益相关方的需求,即用户平均延迟、缓存成本和传输功耗,以及缓存空间有限的约束条件,构建了多目标优化模型,为了求解模型,提出了一种基于最远交配和淘汰策略的多目标进化算法(MOEA-FMES).通过模拟仿真实验与其他常见多目标优化算法进行了对比,结果表明MOEA-FMES优于对比算法,能够给出一组质量较高、收敛性较好且分布均匀的解,证明了所提出方法的有效性.

关键词：多目标移动边缘计算缓存策略进化算法

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红土镍矿内配煤压块还原特性及高温熔分制备镍铁

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中国冶金 2024年第3期34卷 37-46页

作者：张蕊薛正良蒋澳德胡智超林国莫昭育武汉科技大学省部共建耐火材料与冶金国家重点实验室湖北武汉430081 武汉科技大学钢铁冶金及资源利用省部共建教育部重点实验室湖北武汉430081 广西北港新材料有限公司研究院广西北海536017

采用内配煤压块预还原-高温熔分工艺从红土镍矿中提取镍铁合金。研究了褐铁矿型和腐泥土型2种不同性质红土镍矿的矿物特性及其对内配煤压块在不同温度下的还原过程中含铁、镍氧化矿物还原失氧的影响规律,分析了预还原产物高温熔分制备... 详细信息

采用内配煤压块预还原-高温熔分工艺从红土镍矿中提取镍铁合金。研究了褐铁矿型和腐泥土型2种不同性质红土镍矿的矿物特性及其对内配煤压块在不同温度下的还原过程中含铁、镍氧化矿物还原失氧的影响规律,分析了预还原产物高温熔分制备镍铁合金产品的含镍品位和有价元素综合收得率与红土镍矿性质和压块C、O原子物质的量之比n(C)/n(O)之间的关系。结果表明,还原温度对腐泥土型红土镍矿内配煤压块的还原影响很大,n(C)/n(O)为1.2的试样在1 200℃下还原30 min后,含铁、含镍矿物才能被充分还原成金属铁和镍,在较低温度(1 100~1 150℃)下即使延长还原时间也不能进一步提高还原率;褐铁矿型红土镍矿内配煤压块在1 150~1 200℃下还原10 min后,含铁、含镍矿物的还原率分别达到90%以上。红土镍矿内配煤压块在1 200℃预还原30 min后,升温到1 600℃保温30 min进行熔分,获得镍铁合金。用褐铁矿型红土镍矿内配煤压块预还原-熔分得到的镍铁合金中,镍含量随压块n(C)/n(O)增加而下降;相反,用腐泥土型红土镍矿内配煤压块预还原-熔分得到的镍铁合金中,镍含量随压块n(C)/n(O)增加而升高。缺碳配煤(n(C)/n(O)≤1.0)可抑制腐泥土型红土镍矿中含铁矿物的还原,但对含镍矿物还原的抑制作用更强,最终影响镍的综合收得率,降低了镍铁合金的镍含量。本研究可为开发新的红土镍矿火法提取技术、高效利用红土镍矿生产镍铁提供指导。

关键词：红土镍矿镍铁合金内配煤压块碳热还原高温熔分

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Non-LOS target localization via millimeter-wave automotive radar

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Journal of Systems Engineering and Electronics 2023年第5期34卷 1171-1181页

作者： LIU zhaoyu ZHANG Wenli ZHENG Jingyue guo Shisheng CUI guolong KONG Lingjiang LIANG Kun School of Information and Communication Engineering University of Electronic Science and Technology of ChinaChengdu 611731China School of Intelligent Engineering Zhengzhou University of AeronauticsZhengzhou 450046China

This paper considers the non-line-of-sight(NLOS)vehicle localization problem by using millimeter-wave(MMW)automotive radar.Several preliminary attempts for NLOS vehicle detection are carried out and achieve good results.Firstly,an electromagnetic(EM)wave NLOS multipath propagation model for vehicle scene is established.Subsequently,with the help of available multipath echoes,a complete NLOS vehicle localiza-tion algorithm is proposed.Finally,simulation and experimental results validate the effectiveness of the established EM wave propagation model and the proposed NLOS vehicle localization algorithm.

关键词： millimeter-wave(MMW)automotive radar multipath propagation model non-line-of-sight(NLOS)vehicle localization

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基于高分辨率熔解曲线检测MD肿瘤微卫星不稳定性

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畜牧兽医学报 2024年第2期55卷 759-769页

作者：史泽风李翎旭郭译文廖云孙昭宇王来荣杨德吉姚大伟南京农业大学动物医学院南京210095

本研究旨在通过高分辨率熔解曲线(high-resolution melting,HRM)方法检测马立克病(Marek′s disease,MD)肿瘤中存在的微卫星不稳定现象(microsatellite instability,MSI)。通过临床症状、病理剖检、组织病理学、PCR及测序确定为马立克... 详细信息

本研究旨在通过高分辨率熔解曲线(high-resolution melting,HRM)方法检测马立克病(Marek′s disease,MD)肿瘤中存在的微卫星不稳定现象(microsatellite instability,MSI)。通过临床症状、病理剖检、组织病理学、PCR及测序确定为马立克病。采集5只发病鸡的肌肉、肝、脾、血液及肿瘤组织,提取DNA,采用15对扩增微卫星DNA序列的引物进行HRM检测,得到归一化处理的差异熔解曲线,比较分析各组织熔解曲线的差异,分析15个微卫星标记是否存在基因突变(即MSI)。结果表明,发病鸡的各种临床、病理表现符合为马立克病的特征,病毒meq基因序列与近年来国内流行的MDV强毒株有较高的同源性。HRM分析结果显示,MD发病鸡的肌肉、肝、脾、血液、肿瘤组织中微卫星标记PCR扩增后的熔解曲线存在明显的差异,即存在MSI现象,而且不同的病鸡个体和不同的微卫星标记发生MSI的频率不同。15个微卫星标记在5只鸡的病料中存在MSI的微卫星标记的个数分别为14、7、5、3和1。在15个微卫星标记中,MCWO200、MCW0220这两个微卫星标记在所有的病鸡中都存在MSI,而ADL0158微卫星标记在所有的病鸡中都不存在MSI。通过非变性聚丙烯酰胺凝胶电泳和测序分析进一步证明这些微卫星PCR扩增片段确实存在片段大小不同,碱基序列中存在微卫星重复单位的增多、减少或基因片段的插入或缺失。结果提示,通过HRM分析可以检测MD肿瘤中的MSI现象,是一种灵敏、准确、简便、高通量的方法。

关键词：高分辨率熔解曲线马立克病微卫星不稳定性肿瘤

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家畜卵母细胞玻璃化冷冻损伤研究进展

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中国畜牧兽医 2024年第6期51卷 2524-2532页

作者：莫显红李俊杰郭成温诏禹邹宇柱赵文博徐振军赤峰学院化学与生命科学学院赤峰024000 内蒙古赛科星家畜种业与繁育生物技术研究院呼和浩特011517 河北农业大学动物科技学院保定071000

卵母细胞玻璃化冷冻保存对加快优良品种繁育、提高畜牧生产效率、维持物种多样性、拯救濒危动物具有重要意义。目前玻璃化冷冻技术已广泛应用于猪、牛、羊等家畜卵母细胞的冷冻保存。然而,相较新鲜卵母细胞,冷冻-解冻后卵母细胞的成熟... 详细信息

卵母细胞玻璃化冷冻保存对加快优良品种繁育、提高畜牧生产效率、维持物种多样性、拯救濒危动物具有重要意义。目前玻璃化冷冻技术已广泛应用于猪、牛、羊等家畜卵母细胞的冷冻保存。然而,相较新鲜卵母细胞,冷冻-解冻后卵母细胞的成熟率、受精率、卵裂率及囊胚发育率仍然偏低,这显著影响卵母细胞冷冻保存的实际应用。冷冻损伤是制约卵母细胞保存效率与质量的关键。玻璃化冷冻引起卵母细胞透明带破裂、膜脂相变、DNA损伤、染色体异常及胞质内皮质颗粒分布异常、内质网和线粒体结构功能受损、纺锤体形态异常等结构损伤,以及引起细胞氧化应激和钙稳态失衡等生理状态紊乱,导致细胞发育能力降低。因此,认识冷冻损伤产生的原因及其损伤机制,有助于进一步提高卵母细胞冷冻保存效率,促进卵母细胞冷冻技术的提升。作者综述了家畜卵母细胞冷冻损伤类型,分析了冷冻损伤原因,针对不同类型的冷冻损伤提出了改善方法,并对其研究前景进行展望,旨在为提高卵母细胞冷冻保存效率和质量提供参考。

关键词：卵母细胞玻璃化冷冻损伤发育能力家畜

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