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Singularities of Three-Dimensional Cubic Piezoelectric Quasicrystal Composite Wedges and Spaces

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Acta Mechanica Solida Sinica 2023年第1期36卷 143-155页

作者： Xiang Mu Ting Cao Wenshuai Xu zhaowei Zhu Taiyan Qin Liangliang Zhang yang Gao College of Science China Agricultural UniversityBeijing 100083China College of Engineering China Agricultural UniversityBeijing 100083China Key Laboratory of Microgravity Institute of MechanicsChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China

In this paper,the planar problems of three-dimensional(3D)cubic piezoelectric quasicrystal composite wedges and spaces are *** study focuses on the singular behaviors of interface corner and interface crack of composite wedges and *** research the stress singularities,the stress function is assumed to have the exponential *** on the Stroh formalism and Barnett–Lothe matrices,we derive a crucial matrix concerned with material properties and wedge angle and obtain the transcendental equation determining the singular orders by simple multiplication of the crucial *** examples of the singular orders are given for some general cases including single,bi-material,and tri-material wedges and spaces under different boundary *** correctness of numerical results is verified by comparison with the existing results of piezoelectric *** results show that the phonon field,phason field,electric field,material properties,and boundary conditions have great influences on singularities.

关键词： Composite wedges Stroh formalism 3D cubic piezoelectric quasicrystals(QCs) Singular orders

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肺嗜酸性粒细胞浸润症临床特点的回顾性分析

中国呼吸与危重监护杂志 2017年第2期16卷 147-154页

作者：时旭黄夏飞谢佳星张清玲鲜墨杨朝崴顾莹莹关玉宝李靖广州医科大学附属第一医院呼吸疾病国家重点实验室广州呼吸疾病研究所变态反应科广东广州510120

目的观察肺嗜酸性粒细胞浸润症(PIE)的临床资料,探讨PIE的临床特点和诊断经验,提高对该类疾病的认识。方法回顾分析2004年1月至2013年12月广州医科大学附属第一医院临床诊断的48例PIE患者的一般资料、临床表现、实验室检查、影像和病理... 详细信息

目的观察肺嗜酸性粒细胞浸润症(PIE)的临床资料,探讨PIE的临床特点和诊断经验,提高对该类疾病的认识。方法回顾分析2004年1月至2013年12月广州医科大学附属第一医院临床诊断的48例PIE患者的一般资料、临床表现、实验室检查、影像和病理学检查等。结果 48例PIE患者中男27例,女21例,肺嗜酸粒细胞性肉芽肿(肺组织细胞增生症X,PEG)2例,嗜酸粒细胞性肉芽肿性血管炎(EGPA)7例,单纯性肺嗜酸性粒细胞增多症(L?ffler综合征)4例,变应性支气管肺曲菌病(ABPA)16例和慢性嗜酸性粒细胞肺炎(CEP)19例。47.9%的PIE患者曾被诊断哮喘,接受哮喘的规范性治疗但症状仍控制不佳。PEG以喘息、气促为主要表现;外周血嗜酸性粒细胞计数和百分比无明显增高;肺功能以小气道受损明显;影像学见双肺弥漫性小囊状透亮区;病理见肺泡腔嗜酸性粒细胞浸润。EGPA以喘息、咳嗽为主要特征,PIE患者中仅其存在其他器官受累,如四肢麻木;外周血中嗜酸性粒细胞计数、百分比及诱导痰嗜酸性粒细胞百分比增高;肺功能FEV1/FVC和小气道均受损;影像学以树芽征改变为主,且有游走性;病理示PIE中有且仅有本病可见血管外嗜酸性肉芽肿。L?ffler综合征以咳嗽为主,病程短、喘息少见;外周血中嗜酸性粒细胞计数、百分比和诱导痰嗜酸性粒细胞百分比增高常见;肺基础通气和弥散功能无明显下降;影像学示双肺散在密度较淡、边缘欠清的云絮状阴影;病理见肺泡腔、肺间质或血管腔内嗜酸性粒细胞浸润。ABPA临床症状以喘息、咳嗽为最常见,31.3%的ABPA可出现咯血;血嗜酸粒性细胞百分比无显著增高,FEV_1/FVC和小气道均存在明显受损;PIE的影像学仅有ABPA存在中心性支气管扩张;病理示支气管管壁或肺间质嗜酸性粒细胞浸润。CEP以喘息、咳嗽为主,21.1%的CEP表现胸痛;诱导痰嗜酸性粒细胞百分比增高较外周血嗜酸性粒细胞增高更显著;肺功能示其仅存在小气道受损;影像学示84.2%的CEP病灶呈肺周围型胸膜下分布;病理示肺泡腔、肺间质或血管腔内嗜酸性粒细胞浸润。结论 PIE患者大部分以哮喘为初步诊断,即使规范治疗,症状仍控制不佳,应完善相关检查以明确PIE诊断;PIE患者外周血嗜酸性粒细胞增多,多存在肺功能受损,此类疾病的诊断仍主要依据临床表现、实验室检查和影像学、病理学资料做出诊断。

关键词：肺嗜酸性粒细胞浸润症变应性支气管肺曲霉病嗜酸粒细胞性肉芽肿性血管炎

Biosensor-based assay of exosome biomarker for early diagnosis of cancer

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Frontiers of Medicine 2022年第2期16卷 157-175页

作者： Ying Deng zhaowei Sun Lei Wang Minghui Wang Jie yang Genxi Li State Key Laboratory of Pharmaceutical Biotechnology School of Life SciencesNanjing UniversityNanjing 210023China

Cancer imposes a severe threat to people’s health and lives,thus pressing a huge medical and economic burden on individuals and ***,early diagnosis of cancer is indispensable in the timely prevention and effective treatment for *** has recently become an attractive cancer biomarker in noninvasive early diagnosis because of the unique physiology and pathology functions,which reflects remarkable information regarding the cancer microenvironment,and plays an important role in the occurrence and evolution of ***,biosensors have gained great attention for the detection of exosomes due to their superior properties,such as convenient operation,real-time readout,high sensitivity,and remarkable specificity,suggesting promising biomedical applications in the early diagnosis of *** this review,the latest advances of biosensors regarding the assay of exosomes were summarized,and the superiorities of exosomes as markers for the early diagnosis of cancer were ***,the recent challenges and further opportunities of developing effective biosensors for the early diagnosis of cancer were discussed.

关键词： biosensor exosome cancer diagnosis

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手术服的研究进展

产业用纺织品 2021年第2期39卷 1-7页

作者：杨兆薇张淑洁伏立松荆梦轲赵学成天津工业大学纺织科学与工程学院天津300387

为促进手术服在医用纺织品领域的产业化发展,系统介绍手术服用材料及其制备工艺,手术服的接缝工艺,国内外手术服相关测试标准,以及手术服主要性能要求。针对目前手术服在纺织服装领域的研究现状,讨论目前手术服发展存在的一些问题,展望... 详细信息

为促进手术服在医用纺织品领域的产业化发展,系统介绍手术服用材料及其制备工艺,手术服的接缝工艺,国内外手术服相关测试标准,以及手术服主要性能要求。针对目前手术服在纺织服装领域的研究现状,讨论目前手术服发展存在的一些问题,展望其前景和发展趋势。

关键词：手术服医疗卫生测试标准阻隔性能舒适性能抗菌性能

Xp11.2易位/TFE3基因融合相关性肾癌两例报告并文献复习

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微创泌尿外科杂志 2016年第5期5卷 306-311页

作者：杨昭伟孔雪魏文焕孙丹殷磊李泽良孔垂泽中国医科大学附属第一医院泌尿外科沈阳110001

目的:探讨肾癌的罕见类型Xp11.2易位/TFE3基因融合相关性肾癌的临床病理特点、治疗及预后。方法:对本院确诊的2例Xp11.2易位/TFE3基因融合相关性肾癌的临床资料进行回顾性分析并对相关文献进行复习。结果:两例均为左侧,例1确诊时已有远... 详细信息

目的:探讨肾癌的罕见类型Xp11.2易位/TFE3基因融合相关性肾癌的临床病理特点、治疗及预后。方法:对本院确诊的2例Xp11.2易位/TFE3基因融合相关性肾癌的临床资料进行回顾性分析并对相关文献进行复习。结果:两例均为左侧,例1确诊时已有远处转移,采用左肾姑息性切除术,例2采用根治性左肾切除术,免疫组化染色检查均表达TFE3。例1术后随访11个月,病情进展,骨转移加重;例2术后随访12个月,未见复发及远处转移。结论:Xp11.2易位/TFE3基因融合相关性肾癌是由Xp11.2染色体易位,导致转录因子E3(TFE3)基因与多种不同的基因融合的罕见肾癌,淋巴结转移多见,恶性程度较高,结合组织学特征、免疫组化检测TFE3(+)、荧光原位杂交技术有助于确诊,靶向治疗此类型肾癌可能有一定疗效,外科手术是治疗此类型肾肿瘤的首选和根治性治疗方案。

关键词： Xp11.2易位 TFE3基因融合肾肿瘤治疗

吴起油田楼坊坪区块北部长6沉积微相分析研究

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云南化工 2021年第4期48卷 141-143页

作者：曹卫东郭睿婷马旭晴杨兆伟韦悦玉门油田分公司油田作业公司甘肃玉门735019 西安石油大学地球科学与工程学院/陕西省油气成藏重点实验室陕西西安710069 长庆油田分公司第三采气厂内蒙乌审旗017300

为阐明吴起油田楼坊坪区块北部长6沉积特征,在岩心观察描述的基础上,结合取心井段沉积微相分析、砂体对比分析及砂体展布特征研究认为,研究区长6发育三角洲前缘亚相,主要包括水下分流河道、分流间湾和河口坝。其中水下分流河道砂体最大... 详细信息

为阐明吴起油田楼坊坪区块北部长6沉积特征,在岩心观察描述的基础上,结合取心井段沉积微相分析、砂体对比分析及砂体展布特征研究认为,研究区长6发育三角洲前缘亚相,主要包括水下分流河道、分流间湾和河口坝。其中水下分流河道砂体最大,大部分处于研究区中部。长6主要分布2~3支三角洲前缘分流河道砂体,整体呈南北方向分布。结果表明,在研究区长6中长61和长62的连通性最好,而长61的水下分流河道砂体最为发育,连通性也好。油气主要存在于长61和长62的水下分流河道砂体中。

关键词：沉积特征楼坊坪吴起油田长6

A creep model for ultra-deep salt rock considering thermal-mechanical damage under triaxial stress conditions

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第2期16卷 588-596页

作者： Chao Liang Jianfeng Liu Jianxiong yang Huining Xu zhaowei Chen Lina Ran College of Water Resource and Hydropower Sichuan UniversityChengdu610065China CNPC Key Laboratory of Oil and Gas Underground Storage Engineering Langfang065007China CNPC Engineering Technology R&D Company Limited Beijing102206China

To investigate the specific creep behavior of ultra-deep buried salt during oil and gas exploitation,a set of triaxial creep experiments was conducted at elevated temperatures with constant axial pressure and unloading confining pressure *** results show that the salt sample deforms more significantly with the increase of applied temperature and deviatoric *** accelerated creep phase is not occurring until the applied temperature reaches 130℃,and higher temperature is beneficial to the occurrence of accelerated *** describe the specific creep behavior,a novel three-dimensional(3D)creep constitutive model is developed that incorporates the thermal and mechanical variables into mechanical ***,the standard particle swarm optimization(SPSO)method is adopted to fit the experimental data,and the sensibility of key model parameters is analyzed to further illustrate the model *** a result,the model can accurately predict the creep behavior of salt under the coupled thermo-mechanical effect in deep-buried *** on the research results,the creep mechanical behavior of wellbore shrinkage is predicted in deep drilling projects crossing salt layer,which has practical implications for deep rock mechanics problems.

关键词： Creep experiments Creep model Thermal and mechanical damage Fractional derivative

Metamaterial-assisted illumination nanoscopy

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National Science Review 2018年第2期5卷 141-143页

作者： Qian Ma zhaowei Liu Department of Electrical and Computer Engineering University of California San Diego

Traditional optical microscopy resolves fine details of the microscopic worlds,but has its resolution limited by the wave nature of *** to the Abbe diffraction limit d=λ/2NA,whereλand NA represent the light waveleng...

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Satellite proximate interception vector guidance based on differential games

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Chinese Journal of Aeronautics 2018年第6期31卷 1352-1361页

作者： Dong YE Mingming SHI zhaowei SUN Research Center of Satellite Technology Harbin Institute of Technology Harbin Institute of Technology Faculty of Science and Engineering University of Groningen

This paper studies the proximate satellite interception guidance strategies where both the interceptor and target can perform orbital maneuvers with magnitude limited thrusts. This problem is regarded as a pursuit-evasion game since satellites in both sides will try their best to capture or escape. In this game, the distance of these two players is small enough so that the highly nonlinear earth-centered gravitational dynamics can be reduced to the linear Clohessy-Wiltshire（CW） equations. The system is then simplified by introducing the zero effort miss variables. Saddle solution is formulated for the pursuit-evasion game and time-to-go is estimated similarly as that for the exoatmospheric interception. Then a vector guidance is derived to ensure that the interception can be achieved in the optimal time. The proposed guidance law is validated by numerical simulations.

关键词： Differential games Saddle solution Satellite interception Time-to-go estimation Zero effort miss trajectory