检索结果-南通市图书馆

Comprehensive recovery of rare earth elements and gypsum from phosphogypsum:A wastewater free process combining gravity separation and hydrometallurgy

引用

Journal of Rare Earths 2025年第2期43卷 362-370页

作者： Jialin Qing Dapeng zhao li Zeng Guiqing Zhang liang Zhou Jiawei Du Qinggang li Zuoying Cao Shengxi Wu School of Metallurgy and Environment Central South University Key Laboratory of Metallurgical Separation Science and Engineering of Non-ferrous Metals Industry Central South University National Engineering Laboratory for Efficient Utilization of Refractory Non-ferrous Metals Resources Central South University

Comprehensive utilization of phosphogypsum（PG） has attracted much attention,especially for the recovery of rare earth elements（REEs） and gypsum due to the issues of stockpile,environmental pollution,and waste of associated *** utilization methods suffered the issues of low REEs leaching efficiency,huge amount of CaSO4saturated wastewater and high recovery *** solve these issues,this study investigated the occurrence of REEs in PG and the leaching of *** results show that REEs in PG are in the forms of（1） REEs mineral inclusions,（2） REEs isomorphous substitution of Ca2+in gypsum lattice,（3） dispersed soluble REEs *** leaching results demonstrate that（1） the dissolution of gypsum matrix is the control factor of REEs leaching;（2） H2SO4is a promising leachant considering the recycle of leachate;（3） the gypsum matrix suffers a recrystallization during the acid leaching and releases the soluble REEs from PG to aqueous *** the recovery of the undissolved REEs mineral inclusions,wet sieving concentrated 37.1 wt% of the REEs in a 10.7 wt% mass,increasing REEs content from 309 to 1071 ***,a green process combining gravity separation and hydrometallurgy is *** process owns the merits of wastewater free,considerable REEs recovery（about 10% increase compared with traditional processes）,excellent gypsum purification（>95 wt%CaSO4·2H2O,with lical leaching）.

关键词： Gravity separation Phosphogypsum Rare earths Recrystallization reinforcement Wastewater free

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Cholesterol metabolism: physiological versus pathological aspects in intracerebral hemorrhage

引用

Neural Regeneration Research 2025年第4期20卷 1015-1030页

作者： Ruoyu Huang Qiuyu Pang Lexin Zheng Jiaxi lin Hanxi li lingbo Wan tao Wang Department of Forensic Science School of Basic Medicine and Biological SciencesSuzhou Medicine College of Soochow UniversitySuzhouJiangsu ProvinceChina

Cholesterol is an important component of plasma membranes and participates in many basic life functions,such as the maintenance of cell membrane stability,the synthesis of steroid hormones,and *** plays a key role in the establishment and maintenance of the central nervous *** brain contains 20%of the whole body’s cholesterol,80%of which is located within myelin.A huge number of processes(e.g.,the sterol regulatory element-binding protein pathway and liver X receptor pathway)participate in the regulation of cholesterol metabolism in the brain via mechanisms that include cholesterol biosynthesis,intracellular transport,and *** brain injuries or diseases involving crosstalk among the processes above can affect normal cholesterol metabolism to induce detrimental ***,we hypothesized that cholesterol-related molecules and pathways can serve as therapeutic targets for central nervous system *** hemorrhage is the most severe hemorrhagic stroke subtype,with high mortality and *** cholesterol levels are associated with the risk of intracerebral ***,secondary pathological changes after intracerebral hemorrhage are associated with cholesterol metabolism dysregulation,such as neuroinflammation,demyelination,and multiple types of programmed cell *** cholesterol accumulation in the brain has been found after intracerebral *** this paper,we review normal cholesterol metabolism in the central nervous system,the mechanisms known to participate in the disturbance of cholesterol metabolism after intracerebral hemorrhage,and the links between cholesterol metabolism and cell *** also review several possible and constructive therapeutic targets identified based on cholesterol metabolism to provide cholesterol-based perspectives and a reference for those interested in the treatment of intracerebral hemorrhage.

关键词： cell death cholesterol metabolism intracerebral hemorrhage myelination therapeutic target

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

qRfv2, a quantitative resistance locus against Fusarium ear rot in maize

引用

Crop Journal 2025年第1期13卷 41-50页

作者： li, Yanmei tao, Xiaobo Yao, lishan Tang, Sheng Zhang, Xiaohui Tong, lixiu liu, Qingli Song, tao Zhang, Dongfeng Cao, Yingying Zhong, tao Xu, Mingliang State Key Laboratory of Plant Environmental Resilience College of Agronomy and Biotechnology/National Maize Improvement Center/Frontiers Science Center for Molecular Design Breeding China Agricultural University Beijing 100193 China State Key Laboratory of Crop Germplasm Innovation and Molecular Breeding Syngenta Biotechnology (China) Co. Ltd. Beijing 102206 China Seeds Research Syngenta Crop Protection LLC Research Triangle Park Durham 27709 NC United States School of Food Science and Engineering Shaanxi University of Science and Technology Xi'an 710021 Shaanxi China

Fusarium ear rot (FER), caused by Fusarium verticillioides, is a destructive fungal disease of maize. FER resistance is a complex, quantitatively inherited trait controlled by multiple minor-effect genes. In this study, we employed two recombinant inbred line (RIL) populations with the common resistant parental line CML304 to identify FER-resistance loci. Initial QTL analysis identified 23 FER-resistance QTL, each explaining 5.21%–30.51% of the total phenotypic variation. Notably, one major QTL, qRfv2, on chromosome 2 was repeatedly detected, accounting for 11.92%–30.51% of the total phenotypic variation. qRfv2 was fine mapped to an interval of 1.01 Mb, flanked by the markers IDP8 and IDP10. qRfv2 is a semi-dominant resistance gene that could reduce the disease severity index (DSI) by 12.4%–20%, suggesting its potential for enhancing FER resistance in maize. Transcriptome analysis showed that 22 of the 28 annotated functional genes in the qRfv2 region displayed differential expression between parental lines in response to FER. One of the candidate genes, ZmLOX6, was validated to presumably provide a positive effect on FER resistance. Our study provides a basis for the potential cloning and application of FER resistance genes in maize breeding. © 2025 Crop Science Society of China and Institute of Crop Science, CAAS

关键词： Fusarium ear rot Fusarium verticillioides QTL mapping Zea mays

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Carbapenem-resistant Klebsiella pneumoniae infections after liver transplantation:Drug resistance,risk factors and impact on prognosis

引用

World Journal of Gastroenterology 2025年第8期31卷 38-48页

作者： tao-Hua liu li-Hua Chen Qi-Quan Wan Department of Pediatrics The Third Xiangya Hospital of Central South UniversityChangsha 410013Hunan ProvinceChina Department of Laboratory Medicine The Third Xiangya Hospital of Central South UniversityChangsha 410013Hunan ProvinceChina Department of Transplant Surgery The Third Xiangya Hospital of Central South UniversityChangsha 410013Hunan ProvinceChina Engineering and Technology Research Center for Transplantation Medicine of National Health Commission The Third Xiangya Hospital of Central South UniversityChangsha 410013Hunan ProvinceChina

BACKGROUND liver transplant(LT)recipients are susceptible to carbapenem-resistant Klebsiella pneumoniae(CRKP)*** research addressing the incidence,timing,infection sites,resistance patterns,treatment options,and associated risk factors among LT recipients with CRKP is now *** To assess the incidence,resistance,therapy,and risk factors of CRKP infections post-LT,and to evaluate the impact of them on *** A retrospective study was conducted,including 430 consecutive patients who underwent LT between January 2015 and June *** study aimed to investigate the risk factors for CRKP infections and their influence on outcomes using logistic regression *** Among the 430 patients who underwent LT,20(4.7%)experienced at least one documented CRKP infection within 3 months *** median time from LT to the onset of CRKP infections was 6.5 *** lungs and bloodstream were the most common sites of CRKP *** isolates were relatively susceptible to ceftazidime/avibactam(93.7%),polymyxin B(90.6%),and tigecycline(75.0%)***,all isolates were resistant to piperacillin/tazobactam,ceftazidime,cefepime,aztreonam,meropenem,and levofloxacin *** with CRKP infections had a mortality rate of 35%,the rate was 12.5%for those receiving ceftazidime/avibactam *** analysis identified female sex[odds ratio(OR)=3.306;95%confidence interval(CI):1.239-8.822;P=0.017],intraoperative bleeding≥3000 mL(OR=3.269;95%CI:1.018-10.490;P=0.047),alanine aminotransferase on day 1 post-LT≥1500 U/L(OR=4.370;95%CI:1.686-11.326;P=0.002),and post-LT mechanical ventilation(OR=2.772;95%CI:1.077-7.135;P=0.035)as significant variables associated with *** infections were related to an intensive care unit length(ICU)of stay≥7 days and 6-month all-cause mortality *** CRKP infections were frequent complications following LT,with poor associated *** factors for p

关键词： liver transplantation Carbapenem-resistant Klebsiella pneumonia Antibiotic resistance Infection Immunosuppression Risk factors

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Preliminary Design of ITER TBM with Helium-Cooled and Solid Breeder Concept

Southwestern Institute of Physics Annual Report

引用

Southwestern Institute of Physics Annual Report 2005年第1期 87-89页

作者： FENG Kaiming ZHANG Guoshu WANG Xiaoyu CHEN Zhi YUAN tao zhao Zhou li Zengqiang GAO Chunming HU Gang

ITER will play a very important role in first integrated blanket testing in fusion environment. Some DEMO blanket relevant technologies, such as tritium self-sufficiency, extraction of high-grade heat, design criteria... 详细信息

关键词： ITER TBM Tritium breeder

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Plastic flow and interfacial bonding behaviors of embedded linear friction welding process:Numerical simulation combined with thermophysical experiment

引用

Chinese Journal of Aeronautics 2025年第1期38卷 87-98页

作者： Tiejun MA Zhenguo GUO Xiawei YANG Junlong JIN Xi CHEN Jun tao Wenya li Achilles VAIRIS liukuan YU State Key Laboratory of Solidification Processing Shaanxi Key Laboratory of Friction Welding TechnologiesNorthwestern Polytechnical UniversityXi'an 710072China Aeronautical Key Laboratory for Welding and Joining Technologies AVIC Manufacturing Technology InstituteBeijing 100024China Mechanical Engineering Department University of West AtticaAthens 12241Greece Mathematic and Physic Department Xianjiaotong-liverpool UniversitySuzhou 215123China

In this study,a new linear friction welding(LFW)process,embedded LFW process,was put forward,which was mainly applied to combination manufacturing of long or overlong loadcarrying titanium alloy structural components in *** interfacial plastic flow behavior and bonding mechanism of this process were investigated by a developed coupling EulerianLagrangian numerical model using software ABAQUS and a novel thermo-physical simulation method with designed embedded hot compression *** addition,the formation mechanism and control method of welding defects caused by uneven plastic flow were *** results reveal that the plastic flow along oscillating direction of this process is even and *** the direction perpendicular to oscillation,thermo-plastic metals mainly flow downward along welding interface under coupling of shear stress and interfacial pressure,resulting in the interfacial plastic zone shown as an inverted“V”*** upward plastic flow in this direction is relatively weak,and only a small amount of flash is extruded from top of ***,the wedge block and welding components at top of joint are always in un-steady friction stage,leading to nonuniform temperature field distribution and un-welded *** to the results of numerical simulation,high oscillating frequency combined with low pressure and small amplitude is considered as appropriate parameter selection scheme to improve the upward interfacial plastic flow at top of joint and suppress the un-welded *** results of thermo-physical simulation illustrate that continuous dynamic recrystallization(CDRX)induces the bonding of interface,accompanying by intense dislocation movement and creation of many low-angle grain *** the interfacial bonding area,grain orientation is random with relatively low texture density(5.0 mud)owing to CDRX.

关键词： Embedded linear friction welding Plastic flow Interfacial bonding behavior Numerical simulation Thermo-physical simulation Temperature field Dynamic recrystallization

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Integration of CRISPR screening and proteomic analysis of WDR91 manipulation of endosome-to-cytosol transport of African swine fever virus

引用

Science China life Sciences 2025年

作者： Hailong liu Yilin Guo Zishi Guo limeng Sun Dagang tao Xinyun li Guiqing Peng Shuhong zhao Shengsong Xie Key Laboratory of Agricultural Animal Genetics Breeding and Reproduction of Ministry of Education&Key Lab of Swine Genetics and Breeding of Ministry of Agriculture and Rural AffairsHuazhong Agricultural University State Key Laboratory of Agricultural Microbiology College of Veterinary MedicineHuazhong Agricultural University Hubei Hongshan Laboratory Frontiers Science Center for Animal Breeding and Sustainable Production

Dear Editor,African swine fever virus (ASFV) relies heavily on host cellular components for replication, highlighting the complex relationship between the virus and its host(Alcamíet al., 1990). Despite this reliance, the molecular mechanisms governing ASFV infection of host cells remain poorly understood. The low availability of susceptible and permissive cell lines for ASFV replication has hindered research on virus-host interactions, impeding effective antiviral drugs and infection-resistant pig development. Notably, CRISPR screening offers an unbiased and comprehensive method to uncover host factors that are necessary for viral infection,providing a promising avenue for exploring ASFV-host interactions (Puschnik et al., 2017).

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Visible-light-induced ring-opening cross-coupling of cycloalcohols with vinylazaarenes and enones via β-C-C scission enabled by proton-coupled electron transfer

引用

Chinese Chemical Letters 2025年第2期36卷 400-405页

作者： Qinghong Zhang Qiao zhao Xiaodi Wu li Wang Kairui Shen Yuchen Hua Cheng Gao Yu Zhang Mei Peng Kai zhao Institute of Advanced Synthesis School of Chemistry and Molecular EngineeringJiangsu National Synergetic Innovation Center for Advanced MaterialsNanjing Tech University College of Chemical Engineering Nanjing Forestry University College of Pharmacy Hengyang Medical SchoolUniversity of South China School of Chemistry and Chemical Engineering Henan Normal University

Pyridyl-based ketones and 1,6-diketones are both attractive and invaluable scaffolds which play pivotal roles in the construction and structural modification of a plethora of synthetically paramount natural products, pharmaceuticals, organic materials and fine chemicals. In this context, we herein demonstrate an unprecedented, robust and generally applicable synthetically strategy to deliver these two crucial ketone frameworks via visible-light-induced ring-opening coupling reactions of cycloalcohols with vinylazaarenes and enones, respectively. A plausible mechanism involves the selective β-C-C bond cleavage of cycloalcohols enabled by proton-coupled electron transfer and ensuing Giese-type addition followed by single electron reduction and protonation. The synthetic methodology exhibits broad substrate scope,excellent functional group compatibility as well as operational simplicity and environmental friendliness.

关键词： 1,6-Diketone C-C Bond cleavage Proton-coupled electron transfer Pyridyl-based ketone Ring-opening coupling

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Loss-of-function mutations of microRNA-142-3p promote ASH1L expression to induce immune evasion and hepatocellular carcinoma progression

引用

World Journal of Gastroenterology 2025年第1期31卷 126-145页

作者： Xing-Hui Yu Yan Xie Jian Yu Kun-Ning Zhang Zhou-Bo Guo Di Wang zhao-Xian li Wei-Qi Zhang Yu-Ying Tan li Zhang Wen-tao Jiang School of Medicine Nankai UniversityTianjin 300192China Tianjin Key Laboratory of Molecular Diagnosis and Treatment of liver Cancer Tianjin First Center HospitalTianjin 300192China Department of liver Transplantation Tianjin First Center HospitalTianjin 300192China First Central Clinical School Tianjin Medical UniversityTianjin 300192China

BACKGROUND Hepatocellular carcinoma(HCC)has been a pervasive malignancy throughout the world with elevated *** therapeutic targets are beneficial to treat and predict the ***,the exact molecular mechanisms leading to the progression of HCC are still *** has shown that the microRNA-142-3p level decreases in HCC,whereas bioinformatics analysis of the cancer genome atlas database shows the ASH1L expression increased among liver tumor *** this paper,we will explore the effects and mechanisms of microRNA-142-3p and ASH1L affect the prognosis of HCC patients and HCC cell bioactivity,and the association between *** To investigate the effects and mechanisms of microRNA-142-3p and ASH1L on the HCC cell bioactivity and prognosis of HCC *** In this study,we grouped HCC patients according to their immunohistochemistry results of ASH1L with pathological tissues,and retrospectively analyzed the prognosis of HCC ***,explored the roles and mechanisms of microRNA-142-3p and ASH1L by cellular and animal experiments,which involved the following experimental methods:Immunohistochemical staining,western blot,quantitative real-time-polymerase chain reaction,flow cytometric analysis,tumor xenografts in nude mice,*** statistical methods involved in this study contained t-test,one-way analysis of variance,theχ^(2)test,the Kaplan-Meier approach and the log-rank *** In this study,we found that HCC patients with high expression of ASH1L possess a more recurrence rate as well as a decreased overall survival ***1L promotes the tumorigenicity of HCC and microRNA-142-3p exhibits reduced expression in HCC tissues and interacts with ASH1L through targeting the ASH1L 3′untranslated ***,microRNA-142-3p promotes apoptosis and inhibits proliferation,invasion,and migration of HCC cell lines in vitro via *** the exploration mechanism,we found ASH1L may promote an immunosuppressive mi

关键词： Hepatocellular carcinoma MicroRNA-142-3p ASH1L Immune evasion Tumor immune microenvironment Apoptosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The miR3367–lncRNA67–GhCYP724B module regulates male sterility by modulating brassinosteroid biosynthesis and interacting with Aorf27 in Gossypium hirsutum

引用

Journal of Integrative Plant Biology 2025年第1期67卷 169-190页

作者： Anhui Guo Hushuai Nie Huijing li Bin li Cheng Cheng Kaiyun Jiang Shengwei Zhu Nan zhao Jinping Hua Laboratory of Cotton Genetics Genomics and Breeding/Joint Laboratory for International Cooperation in Crop Molecular BreedingMinistry of Education/Beijing Key Laboratory of Crop Genetic ImprovementCollege of Agronomy and BiotechnologyChina Agricultural UniversityBeijing 100193China Key Laboratory of Plant Molecular Physiology Institute of BotanyChinese Academy of SciencesBeijing 100093China

Cytoplasmic male sterile(CMS)lines play a crucial role in utilization of heterosis in crop ***,the mechanism underlying the manipulation of male sterility in cotton by long non-coding RNA(lncRNA)and brassinosteroids(BRs)remains ***,using an integrative approach combining lncRNA transcriptomic profiles with virus-induced gene silencing experiments,we identify a flower budspecific lncRNA in the maintainer line 2074B,lncRNA67,negatively modulating with male sterility in upland cotton(Gossypium hirsutum).lncRNA67positively regulates cytochrome P274B(GhCYP724B),which acted as an eTM(endogenous target mimic)for *** suppression of GhCYP724B induced symptoms of BR deficiency and male semisterility in upland cotton as well as in tobacco,which resulted from a reduction in the endogenous BR ***724B regulates BRs synthesis by interacting with GhDIM and GhCYP90B,two BRs biosynthesis ***,GhCYP724B suppressed a unique chimeric open reading frame(Aorf27)in 2074A mitochondrial *** expression of Aorf27 in yeast inhibited cellular growth,and over expression of Aorf27 in tobacco showed male ***,the results proved that the miR3367–lncRNA67–GhCYP724B module positively regulates male sterility by modulating BRs *** findings uncovered the function of lncRNA67–GhCYP724B in male sterility,providing a new mechanism for understanding male sterility in upland cotton.

关键词： brassinosteroids GhCYP724B lncRNA67 male sterility mitochondrial Aorf27 upland cotton(G.hirsutum)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：