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Perinatal outcomes of frozen-thawed embryo transfer following blastocyst-stage embryo transfer compared to those of cleavage-stage embryo transfer:analysis of 9408 singleton newborns using propensity score analysis

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Reproductive and Developmental Medicine 2024年第2期8卷 67-74页

作者： Hu-Cen zhong Qi Wan Yu-Ling Hu Tian Li Li-Juan Huang Mao Wang Xin-Yue Hu Meng-Di Wang zhao-hui zhong School of Public Health Joint International Research Laboratory of Reproduction and Development of the Ministry of Education of ChinaChongqing 400016China Department of Obstetrics and Gynecology West China Second HospitalSichuan UniversityChengdu 610041China Sichuan Jinxin Xinan Women and Children’s Hospital Chengdu 610041 SichuanChina Department of Reproductive Medicine the First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China School of Public Health Research Center for Medical and Social DevelopmentChongqing Medical UniversityChongqing 400016China

Objective:Regarding frozen-thawed embryo transfer(FET),there is limited consensus on whether extending embryo culture from the cleavage stage to the blastocyst stage affects perinatal *** study aimed to compare perinatal outcomes of singletons between blastocyst-stage embryo transfer(BT)and cleavage-stage embryo transfer(CT)in ***:A total of 9408 FET cycles that met the inclusion criteria were included in this retrospective cohort study between 2019 and ***-stage embryo transfers were performed in the BT group,and cleavage-stage embryo transfers were performed in the CT *** logistic regression analyses were performed,as well as propensity score matching(PSM)to adjust for ***:After PSM,a higher risk of pre-term birth(PTB;odds ratio[OR]:1.23,95%confidence interval[CI]:1.00-1.50,P=0.048)and being large for gestational age(LGA;OR:1.16,95%CI:1.00-1.35,P=0.050)was observed in the BT group compared to that in the CT *** stratified PSM,in the subgroup under 35 years of age,only an increased risk of LGA was observed in the BT group compared to the CT *** outcomes in the double-embryo transfer subgroup were similar to those in the unstratified ***,in the subgroup beyond 35 years of age and the single embryo transfer subgroup,perinatal outcomes were not statistically different between the BT and CT groups(P>0.05).Conclusions:In FET,prolonged embryo culture to the blastocyst stage increased the risk of PTB and LGA in single ***,stratified analysis based on age and the number of transferred embryos yielded different results,necessitating further mechanistic studies.

关键词： Frozen-thawed embryo transfer Blastocyst Cleavage stage Perinatal outcomes Pre-term birth Large for gestational age Small for gestational age

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Effects of ovarian response prediction index and follicle-oocyte index on pregnancy outcomes:a retrospective cohort study of 12,218 fresh transfer cycles

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Reproductive and Developmental Medicine 2024年第3期8卷 151-161页

作者： Mao Wang Li Tan Yu-Bin Ding Xiao-Jun Tang Tian Li Xin-Yue Hu Hu-Cen zhong Qi Wan zhao-hui zhong Department of Epidemiology School of Public HealthResearch Center for Medicine and Social DevelopmentInnovation Center for Social Risk Governance in HealthChongqing Medical UniversityChongqing 400016China The Reproductive Center Chengdu Xinan Gynecology HospitalChengdu 610011China Joint International Research Laboratory of Reproduction and Development of the Ministry of Education of China School of Public HealthChongqing Medical UniversityChongqing 400016China Academician Workstation Department of PharmacologyChangsha Medical UniversityChangsha 410219China The Department of Reproductive Medicine the First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Gynecology and Obstetrics West China Second HospitalSichuan UniversityChengdu 610041China

Objective:To investigate the potential relationships among the ovarian response prediction index(ORPI),follicle-oocyte index(FOI),and clinical pregnancy rate(CPR)in women undergoing their first in vitro fertilization/intracytoplasmic sperm injectionembryo transfer(IVF/ICSI-ET)fresh cycle ***:In this retrospective cohort study,we included 12,218 women who underwent their first IVF/ICSI-ET cycle between December 2014 and January *** primary and secondary outcomes of our study were CPR and cumulative live birth rate(CLBR),*** data were divided into three groups according to the ORPI and FOI *** logistic regression analyses,stratification analyses,interaction,restricted cubic splines,and receiver operating characteristic(ROC)curves were constructed to identify the relationships among ORPI,FOI,and ***:A statistically significant increase in CPR was detected from the lowest to the highest tertile group(ORPI:48.12%,54.07%,and 53.47%,P<0.001;FOI:49.99%,52.95%,and 52.71%,P=0.012).A higher CLBR was observed in the high group(ORPI:38.63%,44.62%,and 44.19%,P<0.001;FOI:41.02%,43.78%,and 42.59%,P=0.039).Multivariate logistic regression analysis revealed no statistically significant differences between ORPI,FOI,and neither CPR(odds ratio[OR][95%confidence interval{CI}],0.99[0.97–1.00]vs.[1.02{0.84–1.24}])nor CLBR(OR[95%CI],0.99[0.97–1.01]vs.0.99[0.81–1.20]).No significant association was found among FOI,ORPI,and CPR,even in the *** cubic spline analyses indicated the existence of a non-linear relationship across the entire range of FOI and *** ORPI and FOI variables had poor predictive ability(AUC<0.60)for ***:Both ORPI and FOI are not reliable predictors of clinical pregnancy or live birth outcomes in fresh *** and researchers should avoid using FOI and ORPI to assess pregnancy outcomes after fresh ET because of their limited relevance and predictive value.

关键词： In vitro fertilization Controlled ovarian hyperstimulation Ovarian response indexes Ovarian response prediction index Follicle-oocyte index Clinical pregnancy

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Effect of endometrial thickness on the risk of ectopic pregnancy for frozen embryo transfer

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Reproductive and Developmental Medicine 2024年第2期8卷 75-81页

作者： Li-Juan Huang Qu Zheng Xue-Jiao Wang zhao-hui zhong Li-Juan Fu Xing-Yu Lv Li-Hong Geng Xiao-Jun Tang Yu-Bin Ding Qi Wan Department of Obstetrics and Gynecology Women and Children’s Hospital of Chongqing Medical UniversityChongqing 401147China School of Public Health Joint International Research Laboratory of Reproduction and Development of the Ministry of Education of ChinaChongqing 400016China The Reproductive Center Chengdu Xinan Gynecology HospitalChengdu 610011China School of Public Health Research Center for Medical and Social DevelopmentChongqing Medical UniversityChongqing 400016China Department of Pharmacology Academician WorkstationChangsha Medical UniversityChangsha 410119China Department of Obstetrics and Gynecology West China Second HospitalSichuan UniversityChengdu 610041China

Objective:Few studies have explored the suitability of endometrial thickness(EMT)as a predictor of ectopic pregnancy(EP)in frozen embryo transfer(FET)*** study aimed to investigate the association between EMT and EP and explore the cutoff value of EMT to predict ***:This retrospective cohort study included women aged 20-45 years undergoing FET between March 2015 and September *** primary outcomes and measured variables were EP and EMT,*** threshold effect of EMT on EP was calculated based on a constructed smooth curve *** patients were divided into two groups based on the threshold for comparison.A subgroup analysis was conducted to examine whether the relationship between EMT and EP remained consistent across the different ***,a generalized linear model was used to analyze the interactions between the treatment factors and EMT in ***:In total,27,549 FET cycles were included,with 27,086 intrauterine and 463 ectopic *** risk of EP in the EMT≤8.7 mm group was 3.36 times higher than that in the EMT>8.7 mm group(odds ratio[OR]:3.36,95%confidence interval[CI]:2.57-4.05).Subgroup analysis further indicated that a thin EMT was a risk factor for EP,independent of other *** also noted that diminished ovarian reserve,tubal factor infertility,transfer of two embryos,or transfer of cleavage-stage embryos may further enhance the risk of EP in patients with thin ***:Thin endometrium was associated with an increased risk of *** with EMT less than 8.7 mm need close medical observation and management after embryo *** addition,diminished ovarian reserve,tubal factor infertility,transfer of two embryos,or transfer of cleavage-stage embryos may significantly enhance the effect of a thin endometrium on the risk of EP.

关键词： Endometrial thickness Thin endometrium Ectopic pregnancy FET cycle Risk factors

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铝铌渣的性能及其热稳定性机制研究

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耐火材料 2024年第2期58卷 116-121页

作者：龚帅赵惠忠余俊张寒谈利强武汉科技大学省部共建耐火材料与冶金国家重点实验室湖北武汉430081 浙江父子岭特种耐火材料有限公司浙江湖州313108

为开发利用铝热还原法制备金属铌工艺中产生的一种有色冶金废渣——铝铌渣,采用ICP、XRD、SEM、TG-DTA等表征技术对铝铌渣的化学组成、物相组成、显微结构及性能进行研究,结果发现,铝铌渣中Nb及NbO的氧化,导致铝铌渣的体积热稳定性非常... 详细信息

为开发利用铝热还原法制备金属铌工艺中产生的一种有色冶金废渣——铝铌渣,采用ICP、XRD、SEM、TG-DTA等表征技术对铝铌渣的化学组成、物相组成、显微结构及性能进行研究,结果发现,铝铌渣中Nb及NbO的氧化,导致铝铌渣的体积热稳定性非常差。将铝铌渣经400~1500℃热处理后发现:高温预烧处理能有效解决铝铌渣体积热稳定性差的问题;经≥1400℃预烧处理后,铝铌渣的物相组成、体积变化率均达稳定状态,且耐火度大于1790℃,满足耐火材料对原料的基本要求,为其资源化利用奠定了良好的基础。

关键词：铝铌渣热稳定性物相组成资源化利用

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Effect of Processing Condition on Texture and Drawability of a Ferritic Rolled and Annealed Interstitial-Free Steel

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Journal of Iron and Steel Research International 2006年第6期13卷 60-65页

作者： WANG zhao-dong GUO Yan-hui zhao zhong LIU Xiang-hua WANG Guo-dong State Key Lab of Rolling and Automation Northeastern University Shenyang 110004 Liaoning China

The processing conditions of the texture formation and deep drawability of a Ti-IF steel strip hot-rolled in ferritic region and subsequently annealed were investigated. The r-value increases with the decrease of reheating temperature, and finish rolling temperature and the increase of reductions in ferritic region. For lubricated ferritic rolling and annealing, the r-value is raised up to 1.75, and elongation rate is over 50% at the finish rolling temperature of 650 ℃, which is suitable for DDQ grade products. However, the r-value is below 1.0 in the case of unlubricated rolling. The X-ray diffraction was used to analyze the textural characteristic of samples. For samples subjected to lubricated rolling and annealing, the strong { 111 }//ND recrystallization texture is distributed homogeneously along the thickness direction, and the intensity of { 110} recrystallization texture is very low even in surface. However, for unlubricated samples, the {111} texture is distributed inhomogeneously and is weak along the thickness direction, and （110}//ND recrystallization texture is strong, which deteriorates the formability.

关键词： IF steel ferritic rolling annealing deep drawability texture

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MIL-96(Al)及其复合吸附剂的合成及水吸附性能研究

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应用化工 2024年第5期53卷 1047-1052,1057页

作者：奚之皓赵惠忠王清戈苗春勃刘成凤上海海事大学商船学院上海201306

通过溶剂热合成法制备了铝基金属有机骨架材料MIL-96(Al),并通过浸渍法合成了复合吸附剂MIL-96(Al)-L。通过扫描电子显微镜(SEM)讨论了所制备吸附剂的形貌。在不同工况的吸附实验中,MIL-96(Al)具有稳定的平衡吸附量,吸湿盐LiCl的加入增... 详细信息

通过溶剂热合成法制备了铝基金属有机骨架材料MIL-96(Al),并通过浸渍法合成了复合吸附剂MIL-96(Al)-L。通过扫描电子显微镜(SEM)讨论了所制备吸附剂的形貌。在不同工况的吸附实验中,MIL-96(Al)具有稳定的平衡吸附量,吸湿盐LiCl的加入增强了复合吸附剂的吸水性能。在吸附速率方面,MIL-96(Al)及其复合吸附剂表现出优异的性能。在不同温度和湿度条件下,MIL-96(Al)的吸附速率相对稳定,最高可达0.172 g/(g·h),而在相同条件下,MIL-96(Al)-L3的吸附速率最高可达MIL-96(Al)的3.7倍。MIL-96(Al)及其复合吸附剂在110℃下,可在30 min内完成脱附。其循环稳定性也通过循环再生实验得到证实。结果表明,MIL-96(Al)-L复合吸附剂是一种可实际应用于干旱地区的太阳能空气取水吸附剂。

关键词：金属有机骨架太阳能空气取水复合吸附剂开式吸附

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Kinematics Analysis Based on Screw Theory of a Humanoid Robot

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Journal of China University of Mining and Technology 2007年第1期17卷 49-52页

作者： MAN Cui-hua FAN Xun LI Cheng-rong zhao zhong-hui School of Mechanical Electronic and Information Engineering China University of Mining ＆ Technology Beijing 100083 China Institute of Automation Chinese Academy of Sciences Beijing 100080 China

A humanoid robot is a complex dynamic system for its idiosyncrasy. This paper aims to provide a mathematical and theoretical foundation for the design of the configuration, kinematics analysis of a novel humanoid robot. It has a simplified configuration and design for entertainment purpose. The design methods, principle and mechanism are discussed. According to the design goals of this research, there are ten degrees of freedom in the two bionic arms. Modularization, concurrent design and extension theory methods were adopted in the configuration study and screw theory was introduced into the analysis of humanoid robot kinematics. Comparisons with other methods show that: 1) only two coordinates need to be established in the kinematics analysis of humanoid robot based on screw theory; 2) the spatial manipulator Jacobian obtained by using twist and exponential product formula is succinct and legible; 3) adopting screw theory to resolve the humanoid robot arms kinematics question can avoid singularities; 4) using screw theory can solve the question of specification insufficiency.

关键词： bionics arm screw theory extension theory Jacobian matrix modularization design

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Super-high bed sintering for iron ores:behaviors,causes and solutions of horizontal segregation on strand

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Journal of Iron and Steel Research International 2024年第7期31卷 1590-1596页

作者： Liang-ping Xu hui-bo Liu zhong-lin Dong Qiang zhong Yu-chao zhao Guang-hui Li School of Minerals Processing and Bioengineering Central South UniversityChangsha 410083HunanChina

Horizontal segregation has been a constraint to the development and application of super-high bed *** eliminate the horizontal segregation of super-high bed sintering,several typical sintering machines were sampled and analyzed,and theoretical calculation was made to compare the bed depth and their differences in different areas within the mixture ***,solutions were proposed and applied to a 265 m^(2) sintering *** results showed that the horizontal seg-regation of the 265 m^(2) sintering machine was dominated by particles larger than 8 mm with horizontal segregation degree of 0.48,while 360 and 550 m^(2) sintering machines were affected by 5-8 mm and 1-3 mm particles with horizontal segregation degree of 0.27 and 0.31,*** analysis indicated the different segregation distribution results from the matching of the bed depth of each area within the mixture ***,the horizontal segregation degree not larger than 0.06 was achieved by optimizing the time parameters and the division of three zones on the 265 m^(2) sintering machine.

关键词： Super-high bed sintering Horizontal segregation Feeder Particle distribution Agglomeration

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A deep kernel method for lithofacies identification using conventional well logs

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Petroleum Science 2023年第3期20卷 1411-1428页

作者： Shao-Qun Dong zhao-hui zhong Xue-hui Cui Lian-Bo Zeng Xu Yang Jian-jun Liu Yan-Ming Sun jing-Ru Hao State Key Laboratory of Petroleum Resources and Prospecting China University of PetroleumBeijing102249China Collge of Science China University of PetroleumBeijing102249China College of Geoscience China University of PetroleumBeijing102249China

How to fit a properly nonlinear classification model from conventional well logs to lithofacies is a key problem for machine learning *** methods(e.g.,KFD,SVM,MSVM)are effective attempts to solve this issue due to abilities of handling nonlinear features by kernel *** mining of log features indicating lithofacies still needs to be improved for kernel ***,this work employs deep neural networks to enhance the kernel principal component analysis(KPCA)method and proposes a deep kernel method(DKM)for lithofacies identification using well *** includes a feature extractor and a *** feature extractor consists of a series of KPCA models arranged according to residual network structure.A gradient-free optimization method is introduced to automatically optimize parameters and structure in DKM,which can avoid complex tuning of parameters in *** test the validation of the proposed DKM for lithofacies identification,an open-sourced dataset with seven con-ventional logs(GR,CAL,AC,DEN,CNL,LLD,and LLS)and lithofacies labels from the Daniudi Gas Field in China is *** are eight lithofacies,namely clastic rocks(pebbly,coarse,medium,and fine sand-stone,siltstone,mudstone),coal,and carbonate *** comparisons between DKM and three commonly used kernel methods(KFD,SVM,MSVM)show that(1)DKM(85.7%)outperforms SVM(77%),KFD(79.5%),and MSVM(82.8%)in accuracy of lithofacies identification;(2)DKM is about twice faster than the multi-kernel method(MSVM)with good *** blind well test in Well D13 indicates that compared with the other three methods DKM improves about 24%in accuracy,35%in precision,41%in recall,and 40%in F1 score,*** general,DKM is an effective method for complex lithofacies *** work also discussed the optimal structure and classifier for *** re-sults show that(m_(1),m_(2),O)is the optimal model structure and linear svM is the optimal classifier.(m_(1),m_(2),O)means there

关键词： Lithofacies identification Deepkernel method Well logs Residual unit Kernel principal component analysis Gradient-free optimization

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Study of deep transportation and plugging performance of deformable gel particles in porous media

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Petroleum Science 2024年第2期21卷 962-973页

作者： Wen-Jing zhao Jing Wang zhong-Yang Qi hui-Qing Liu National Key Laboratory of Petroleum Resources and Engineering China University of PetroleumBeijing102249China MOE Key Laboratory of Petroleum Engineering China University of PetroleumBeijing102249China

Deformable gel particles(DGPs) possess the capability of deep profile control and flooding. However, the deep migration behavior and plugging mechanism along their path remain unclear. Breakage, an inevitable phenomenon during particle migration, significantly impacts the deep plugging effect. Due to the complexity of the process, few studies have been conducted on this subject. In this paper, we conducted DGP flow experiments using a physical model of a multi-point sandpack under various injection rates and particle sizes. Particle size and concentration tests were performed at each measurement point to investigate the transportation behavior of particles in the deep part of the reservoir. The residual resistance coefficient and concentration changes along the porous media were combined to analyze the plugging performance of DGPs. Furthermore, the particle breakage along their path was revealed by analyzing the changes in particle size along the way. A mathematical model of breakage and concentration changes along the path was established. The results showed that the passage after breakage is a significant migration behavior of particles in porous media. The particles were reduced to less than half of their initial size at the front of the porous media. Breakage is an essential reason for the continuous decreases in particle concentration, size, and residual resistance coefficient. However, the particles can remain in porous media after breakage and play a significant role in deep plugging. Higher injection rates or larger particle sizes resulted in faster breakage along the injection direction, higher degrees of breakage, and faster decreases in residual resistance coefficient along the path. These conditions also led to a weaker deep plugging ability. Smaller particles were more evenly retained along the path, but more particles flowed out of the porous media, resulting in a poor deep plugging effect. The particle size is a function of particle size before inject

关键词： Physical simulation Deformable gel particle Breakage Particle size Residual resistance coefficient

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