检索结果-南通市图书馆

Whole exome sequencing identifies risk variants associated with intracranial epidermoid cyst deterioration:A case report

引用

World Journal of Clinical Oncology 2024年第11期15卷 1428-1434页

作者： zhao-na song Yan Cheng Dan-Dan Wang Ming-Jun Li Xiang-Rong zhao Fa-Wang Li Zhen Liu Xiao-Ru Zhu Xiao-Dong Jia Yu-Fang Wang Feng-Fan Liang Joint Laboratory for Translational Medicine Research Liaocheng People's HospitalLiaocheng 252000Shandong ProvinceChina Harbin Genars Technology Co. Ltd.Harbin 150060Heilongjiang ProvinceChina Department of Radiotherapy Liaocheng People's HospitalLiaocheng 252000Shandong ProvinceChina Department of Medical laboratory Qilu Hospital of Shandong University Dezhou HospitalDezhou 253600Shandong ProvinceChina

BACKGROUND Intracranial epidermoid cyst(IEC)transformation to malignant squamous cell carcinoma(SCC)is extremely rare,and its etiology is yet ***,SCC is treated by performing surgery,followed by a combination of radiotherapy and *** is crucial to identify efficient and trustworthy therapeutic targets for SCC to improve its diagnosis,prognosis,and *** SUMMARY In this study,we report the case of a 47-year-old female patient with SCC,which progressed from IEC in the left internal capsule *** patient was sought treatment at our hospital for severe diplopic vision,accompanied with speech disorder and memory *** on the clinical and postoperative pathology,this patient was finally diagnosed with *** identify disease-causing variants,whole exome sequencing(WES)was performed on the *** revealed two pathogenic missense mutations on Gap junction protein beta 2(GJB2)(c.257C>T)and Toll-like receptor 2(TLR2)(c.1039A>G),*** This study provided the first clinical evidence for demonstrating the role of GJB2 and TLR2 in IEC development and *** further confirmed WES as a robust and reliable technique for underlying rare and complex disease-related genetic factor identification.

关键词： Intracranial epidermoid cyst Squamous cell carcinoma Whole exome sequencing Variants Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Alleviation of the plastic deformation of gel ink under strong stress through an esterification of xanthan gum reinforcing its double helix structure

引用

Chinese Journal of Chemical Engineering 2024年第3期67卷 49-57页

作者： Xiaokun Li Mingyi Wang Zilu Liu song Yang na Xu Wei zhao Gan Luo Shoujun Liu College of Chemical Engineering and Technology Taiyuan University of TechnologyTaiyuan 030024China Shanxi Engineering Center of Civil Clean Fuel Taiyuan University of TechnologyTaiyuan 030024China Shanxi Coking Coal in Yuncheng Salt Refco Group Ltd. Yuncheng 044000China

As a natural organic polymer,xanthan gum(XG)can alleviate the plastic deformation of gel ink under strong stress and realize the reasonable regulation of the rheological properties of gel ***,as the double-helix structure connected by hydrogen bonds cannot resist the mechanical environment of strong stress,XG shows poor shear *** this study,a polymer gel with interpenetrating polymer network structure was prepared by esterifying XG,taking polystyrene maleic anhydride(SMA)as the *** addition to retaining the excellent rheological properties of XG,the generated polymer gel also exhibited high shear *** optimal addition amount of the esterification reaction modifier was determined as mXG:mSMA=5:3 according to the gel ink *** this amount,the viscosity of the modified xanthan gum(SXG)gel increased to 1578.8 mPa·s and 100.7 mPa·s at shear rates of 4 s1 and 383 s1,respectively,and the shear resistance increased more than 2 times compared to the unmodified *** is because of the ester bond formed by esterification that the reaction strengthens the interaction between molecular segments,enabling the new gel to resist to strong mechanical *** new polymer gel studied in this paper and the proposed mechanism of action provide new insights for the development of high-end gel ink and also provide theoretical support for the study of rheological properties of non-Newtonian fluids.

关键词： Gel ink Xanthan gum Esterification Simulation Shear resistance Gels

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pr-Tb synergistic strengthening on coercivity of Nd-Ce-Fe-B magnets grain boundary diffused with Pr-Tb-Al-Ga alloys

引用

Journal of Rare Earths 2024年第9期42卷 1704-1709,I0003页

作者： Ruifang song Hang zhao Haibo Feng Institute of Functional Materials Central Iron&Steel Research InstituteBeijing100081China

Sintered Nd-Ce-Fe-B magnets were grain boundary diffused(GBDed) with Pr_(x)Tb_(80-x)Al_(10)Ga_(10)(at%)(x=0,20,40,60,80) *** effect of Pr/Tb content in diffusion source on magnetic properties,microstructure and elements distribution of GBDed magnets was *** Pr is used to substitute for 75% Tb in diffusion source,Tb consumption per unit coercivity improvement of GBDed magnet reduces by 77%,compared with the Tb_(80)Al_(10)Ga_(10) diffused *** element diffuses into magnets and then forms Tb-rich shell with high magneto-crystalline anisotropy field surrounding main phase grains,resulting in substantial coercivity *** with low melting point diffuses deeply along liquid grain boundary phase during GBD *** can eliminate some sharp defects of main phase grains and make grain boundaries smooth,which provides diffusion channels for further diffusion of Tb ***,there are more diffusion channels for Tb and less Tb enriched at surface region,making Tb diffuse more deeply and improving Tb utilization *** method significantly improves the coercivity,and realizes the green,efficient and high-quality utilization of heavy rare earth(HRE)elements.

关键词： Grain boundary diffusion Rare earths Microstructure Synergistic strengthening

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Approximately Bi-Similar Symbolic Model for Discretetime Interconnected Switched System

引用

IEEE/CAA Journal of Automatica Sinica 2024年第10期11卷 2185-2187页

作者： Yang song Yongzhuang Liu Wanqing zhao School of Mechatronic Engineering and Automation Shanghai UniversityShanghai 200444China School of Computing Newcastle UniversityNewcastle upon Tyne NE45TGUK

Dear Editor,This letter concerns the development of approximately bi-similar symbolic models for a discrete-time interconnected switched system(DT-ISS).The DT-ISS under consideration is formed by connecting multiple switched systems known as component switched systems(CSSs).Although the problem of constructing approximately bi-similar symbolic models for DT-ISS has been addressed in some literature,the previous works have relied on the assumption that all the subsystems of CSSs are incrementally input-state stable.

关键词： approximate symbolic connected

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Adaptive Consensus of Uncertain Multi-Agent Systems With Unified Prescribed Performance

引用

IEEE/CAA Journal of Automatica Sinica 2024年第5期11卷 1310-1312页

作者： Kun Li Kai zhao Yongduan song The authors are with the School of Automation Chongqing UniversityChongqing 400044China

Dear Editor,An adaptive consensus control algorithm for uncertain multi-agent systems(MAS),capable of guaranteeing unified prescribed performance,is presented in this *** many existing prescribed performance related works,the developed control exhibits some ***,a distributed prescribed time observer is introduced so that not only each follower is able to estimate the leader’s signal within a predetermined time,but also the control design for each agent is independent with its neighbors.

关键词： agent prescribed Uncertain

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Microstructure evolution and mechanical properties of brazing joint for ultra-thin-walled Inconel 718 considering grain size effect and brazing temperature

引用

Chinese Journal of Aeronautics 2024年第2期37卷 541-556页

作者： Rui zhao Yueshuai song Hui KANG Min WAN School of Mechanical Engineering and Automation Beihang UniversityBeijing 100191China Jiangxi Research Institute of Beihang University Jiangxi 330000China

The systematic investigation of the mechanical properties and microstructure evolution process of ultra-thin-walled Inconel 718 capillary brazing joints is of great significance because of the exceptionally high demands on its *** achieve this objective,this study investigates the impact of three distinct brazing temperatures and five typical grain sizes on the brazed joints’mechanical properties and microstructure evolution *** evolution analysis was conducted based on Electron Back Scatter Diffraction(EBSD),Scanning Electron Microscopy(SEM),X-Ray Diffraction(XRD),High-Resolution Transmission Electron Microscopy(HRTEM),and Focused Ion Beam(FIB).Besides,the mechanical properties and fracture behavior were studied based on the uniaxial tension tests and in-situ tension *** findings reveal that the brazing joint’s strength is higher for the fine-grain capillary than the coarse-grain one,primarily due to the formation of a dense branch structure composed of G-phase in the brazing *** effects of grain size,such as pinning and splitting,are amplified at higher brazing ***,micro-cracks initiate around brittle intermetallic compounds and propagate through the eutectic zone,leading to a cleavage fracture *** fracture stress of fine-grain specimens is higher than that of coarse-grain due to the complex micro-crack ***,this study contributes significantly to the literature by highlighting the crucial impact of grain size on the brazing properties of ultra-thin-walled Inconel 718 structures.

关键词： EYWORDS Ultra-thin-walled structure Brazing Inconel 718 Grain size effect Brazing temperature

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Study on thermal decomposition kinetics of azobenzene-4,4′-dicarboxylic acid by using compensation parameter method and nonlinear fitting evaluation

引用

Chinese Journal of Chemical Engineering 2024年第6期70卷 269-279页

作者： Shuyi Shen song Guo Sining Chen Jinhua zhao nanjing University of Science&Technology Nanjing 210094China China Academy of Safety Science and Technology Beijing 100012China

Recently,azobenzene-4,4'-dicarboxylic acid(ADCA)has been produced gradually for use as an organic synthesis or pharmaceutical intermediate due to its eminent *** large quantities put into application in the future,the thermal stability of this substance during storage,transportation,and use will become quite ***,in this work,the thermal decomposition behavior,thermal decomposition kinetics,and thermal hazard of ADCA were *** were conducted by using a SENSYS evo DSC device.A combination of differential iso-conversion method,compensation parameter method,and nonlinear fitting evaluation were also used to analyze thermal kinetics and mechanism of ADCA *** results show that when conversion rate α increases,the activation energies of ADCA's first and main decomposition peaks *** amount of heat released during decomposition varies between 182.46 and 231.16 J·g^(-1).The proposed kinetic equation is based on the Avrami-Erofeev model,which is consistent with the decomposition *** the Frank-Kamenetskii model,a calculated self-accelerating decomposition temperature of 287.0℃is obtained.

关键词： Azobenzene-4,4′-dicarboxylic acid Thermal decomposition behavior Kinetic mechanism Thermal hazard evaluation Compensation parameter effect

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Multimodal Fusion of Brain Imaging Data: Methods and Applications

引用

Machine Intelligence Research 2024年第1期21卷 136-152页

作者： na Luo Weiyang Shi Zhengyi Yang Ming song Tianzi Jiang Brainnetome Center and national Laboratory of Pattern Recognition Institute of AutomationChinese Academy of SciencesBeijing 100190China School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 100049China Center for Excellence in Brain Science and Intelligence Technology Institute of AutomationChinese Academy of SciencesBeijing 100190China Research Center for Augmented Intelligence Zhejiang LaboratoryHangzhou 311100China

Neuroimaging data typically include multiple modalities,such as structural or functional magnetic resonance imaging,dif-fusion tensor imaging,and positron emission tomography,which provide multiple views for observing and analyzing the *** lever-age the complementary representations of different modalities,multimodal fusion is consequently needed to dig out both inter-modality and intra-modality *** the exploited rich information,it is becoming popular to combine multiple modality data to ex-plore the structural and functional characteristics of the brain in both health and disease *** this paper,we first review a wide spectrum of advanced machine learning methodologies for fusing multimodal brain imaging data,broadly categorized into unsupervised and supervised learning *** by this,some representative applications are discussed,including how they help to under-stand the brain arealization,how they improve the prediction of behavioral phenotypes and brain aging,and how they accelerate the biomarker exploration of brain ***,we discuss some exciting emerging trends and important future ***,we intend to offer a comprehensive overview of brain imaging fusion methods and their successful applications,along with the chal-lenges imposed by multi-scale and big data,which arises an urgent demand on developing new models and platforms.

关键词： Multimodal fusion supervised learning unsupervised learning brain atlas cognition brain disorders

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Emerging interactively stretchable electronics with optical and electrical dual-signal feedbacks based on structural color materials

引用

nano Research 2024年第3期17卷 1837-1855页

作者： Jialin Wang Kai zhao Changqing Ye Yanlin song School of Materials Science and Engineering Suzhou University of Science and TechnologySuzhou 215009China Key Laboratory of Green Printing Institute of ChemistryChinese Academy of SciencesBeijing 100190China

The booming development of wearable devices has aroused increasing interests in flexible and stretchable *** mechanosensory functionality,these devices are highly desirable on account of their wide range of applications in electronic skin,personal healthcare,human–machine interfaces and ***,they are mostly limited by single electrical signal feedback,restricting their diverse applications in visualized mechanical *** by the mechanochromism of structural color materials,interactively stretchable electronics with optical and electrical dual-signal feedbacks are recently emerged as novel sensory platforms,by combining both of their sensing mechanisms and ***,recent studies on interactively stretchable electronics based on structural color materials are *** a brief introduction of their basic components(i.e.,stretchable electronics and mechanochromic structural color materials),two types of interactively stretchable electronics with respect to the nanostructures of mechanochromic materials are outlined,focusing primarily on their design considerations and fabrication ***,the main challenges and future perspectives of these emerging devices are discussed.

关键词： stretchable electronics structural color materials interactive sensing mechanochromism dual-signal feedbacks

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Improvement of Microstructure and Mechanical Properties of Rapid Cooling Friction Stir-welded A1050 Pure Aluminum

引用

Journal of Wuhan University of Technology(Materials Science) 2024年第1期39卷 134-141页

作者：许楠 LIU Lutao song Qining zhao Jianhua BAO Yefeng College of Materials Science and Engineering Hohai UniversityChangzhou 213200China

Two-mm thick A1050 pure aluminum plates were successfully joined by conventional and rapid cooling friction stir welding(FSW), respectively. The microstructure and mechanical properties of the welded joints were investigated by electron backscatter diffraction characterization, Vickers hardness measurements, and tensile testing. The results showed that liquid CO_(2) coolant significantly reduced the peak temperature and increased the cooling rate, so the rapidly cooled FSW joint exhibited fine grains with a large number of dislocations. The grain refinement mechanism of the FSW A1050 pure aluminum joint was primarily attributed to the combined effects of continuous dynamic recrystallization, grain subdivision, and geometric dynamic recrystallization. Compared with conventional FSW, the yield strength, ultimate tensile strength, and fracture elongation of rapidly cooled FSW joint were significantly enhanced, and the welding efficiency was increased from 80% to 93%. The enhanced mechanical properties and improved synergy of strength and ductility were obtained due to the increased dislocation density and remarkable grain refinement. The wear of the tool can produce several WC particles retained in the joint, and the contribution of second phase strengthening to the enhanced strength should not be ignored.

关键词： aluminum alloy friction stir welding recrystallization microstructure mechanical properties

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：