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World Journal of Psychiatry 2024年第1期14卷 148-158页

作者： qun zhao Xing Wang Shu-Fan Li Peng Wang Xiang Wang Xin Xin Suo-Wang Yin zhao-Song Yin Li-Juan Mao School of Physical Education Shanghai University of SportShanghai 200438China Department of Physical Education Donghua UniversityShanghai 201620China

BACKGROUND The detection rate of depression among university students has been increasing in recent years,becoming one of the main psychological diseases that endangers their physical and mental *** to statistics,self-harm and suicide,for which there is no effective intervention,are the second leading causes of *** To explore the relationship between different elements and levels of physical activity and college students’depression-symptom-specific working memory *** Of 143 college students were analyzed using the Beck Depression Self-Rating Scale,the Physical Activity Rating Scale,and the Working Memory *** There was a significant difference between college students with depressive symptoms and healthy college students in completing verbal and spatial working memory(SWM)tasks correctly(all P0.05).CONCLUSION An increase in physical exercise among college students,particularly medium-and high-intensity exercise and exercise of 30 min or more,can improve the correct rate of completing working memory tasks.

关键词： Physical activity Depression symptoms University students Working memory

Tactile Paving Recognition Method Based on Improved YOLOv7

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Journal of Electronic Research and Application 2024年第4期8卷 22-27页

作者： Chengyi Shi qun zhao Nan Fang Yufeng Mao School of Computer Engineering Nanjing Institute of TechnologyNanjing 211167China NR Electric Co. Ltd.Nanjing 211102China

Tactile paving is a professional road facility to ensure the safe travel of people with visual ***,there are many problems with tactile paving travel in *** one,some tactile paving is seriously damaged,and the other is the accumulation of *** to help visually impaired people recognize and locate obstacles in tactile paving is a problem worth *** this paper,image recognition technology is used to recognize the tactile paving pictures with obstacles,and an attention mechanism is used to optimize samples to improve recognition accuracy.

关键词： YOLOv7 Tactile paving recognition Attention mechanism

CALD1 facilitates epithelial-mesenchymal transition progression in gastric cancer cells by modulating the PI3K-Akt pathway

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 1029-1045页

作者： Wen-Qian Ma Ming-Chang Miao Ping-An Ding Bi-Bo Tan Wen-Bo Liu Shuo Guo Li-Mian Er Zhi-Dong Zhang qun zhao Department of Endoscopy The Fourth Hospital of Hebei Medical UniversityShijiazhuang 050011Hebei ProvinceChina Hebei Key Laboratory of Precision Diagnosis and Comprehensive Treatment of Gastric Cancer Shijiazhuang 050011Hebei ProvinceChina Department of Radiotherapy The Fourth Hospital of Hebei Medical UniversityShijiazhuang 050011Hebei ProvinceChina The Third Department of Surgery The Fourth Hospital of Hebei Medical UniversityShijiazhuang 050011Hebei ProvinceChina

BACKGROUND CALD1 has been discovered to be abnormally expressed in a variety of malignant tumors,including gastric cancer(GC),and is associated with tumor progression and immune infiltration;however,the roles and mechanisms of CALD1 in epithe-lial-mesenchymal transition(EMT)in GC are *** To investigate the role and mechanism of CALD1 in GC progression,invasion,and *** In this study,the relationship between CALD1 and GC,as well as the possible network regulatory mechanisms of CALD1,was investigated by bioinformatics and validated by ***1-siRNA was synthesized and used to trans-fect GC *** activity was measured using the CCK-8 method,cell migration and invasive ability were measured using wound healing assay and Transwell assay,and the expression levels of relevant genes and proteins in each group of cells were measured using qRT-PCR and Western blot.A GC cell xenograft model RESULTS Bioinformatics results showed that CALD1 was highly expressed in GC tissues,and CALD1 was significantly higher in EMT-type GC tissues than in tissues of other types of *** prognosis of patients with high expression of CALD1 was worse than that of patients with low expression,and a prognostic model was constructed and *** experimental results were consistent with the results of the bioinformatics *** expression level of CALD1 in GC cell lines was all higher than that in gastric epithelial cell line GES-1,with the strongest expression found in AGS and MKN45 *** activity was significantly reduced after CALD1-siRNA trans-fection of AGS and MKN45 *** ability of AGS and MKN45 cells to migrate and invade was reduced after CALD1-siRNA transfection,and the related mRNA and protein expression was *** to bioinfor-matics findings in GC samples,the CALD1 gene was significantly associated with the expression of members of the PI3K-AKT-mTOR signaling pathway as well as the EMT signaling pathway,and was closely rel

关键词： Gastric tumor CALD1 Epithelial-mesenchymal transition Gene disruption Invasion Migration Bioinformatics

Rapid development of double-hit mRNA antibody cocktail against orthopoxviruses

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Signal Transduction and Targeted Therapy 2024年第4期9卷 1768-1776页

作者： Hang Chi Suo-qun zhao Ru-Yi Chen Xing-Xing Suo Rong-Rong Zhang Wen-Hui Yang Dong-Sheng Zhou Min Fang Bo Ying Yong-Qiang Deng Cheng-Feng Qin State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and EpidemiologyAMMS100071BeijingChina College of Life Sciences Inner Mongolia Agricultural UniversityHohhot010018Inner MongoliaChina School of Life Sciences Henan UniversityKaifeng475004HenanChina Suzhou Abogen Biosciences Co. LtdSuzhou215123JiangsuChina Research Unit of Discovery and Tracing of Natural Focus Diseases Chinese Academy of Medical Sciences100071BeijingChina

The Orthopoxvirus genus,especially variola virus(VARV),monkeypox virus(MPXV),remains a significant public health threat *** development of therapeutic antibodies against orthopoxviruses is largely hampered by the high cost of antibody engineering and manufacturing ***-encoded antibodies have emerged as a powerful and universal platform for rapid antibody ***,by using the established lipid nanoparticle(LNP)-encapsulated mRNA platform,we constructed four mRNA combinations that encode monoclonal antibodies with broad neutralization activities against *** vivo characterization demonstrated that a single intravenous injection of each LNP-encapsulated mRNA antibody in mice resulted in the rapid production of neutralizing *** importantly,mRNA antibody treatments showed significant protection from weight loss and mortality in the vaccinia virus(VACV)lethal challenge mouse model,and a unique mRNA antibody cocktail,Mix2a,exhibited superior in vivo protection by targeting both intracellular mature virus(IMV)-form and extracellular enveloped virus(EEV)-form *** summary,our results demonstrate the proof-of-concept production of orthopoxvirus antibodies via the LNP-mRNA platform,highlighting the great potential of tailored mRNA antibody combinations as a universal strategy to combat orthopoxvirus as well as otheremerging viruses.

关键词： proof universal neutral

Comparative analysis of two digestive tract reconstruction methods in total laparoscopic radical total gastrectomy

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World Journal of Gastrointestinal Surgery 2024年第4期16卷 1109-1120页

作者： Tian-Xiang Dong Dong Wang qun zhao Zhi-Dong Zhang Xue-Feng zhao Bi-Bo Tan Yu Liu Qing-Wei Liu Pei-Gang Yang Ping-An Ding Tao Zheng Yong Li Zi-Jing Liu Third Department of Surgery of the Fourth Hospital of Hebei Medical University Hebei Key Laboratory of Precision Diagnosis and Comprehensive Treatment of Gastric CancerShijiazhuang 050011Hebei ProvinceChina

BACKGROUND The incidence of gastric cancer has significantly increased in recent *** resection is the main treatment,but the method of digestive tract reconstruction after gastric cancer surgery remains *** the current study,we sought to explore a reasonable method of digestive tract reconstruction and improve the quality of life and nutritional status of patients after *** this end,we statistically analyzed the clinical results of patients with gastric cancer who underwent jejunal interposition double-tract reconstruction(DTR)and esophageal jejunum Roux-en-Y reconstruction(RY).AIM To explore the application effect of DTR in total laparoscopic radical total gastrectomy(TLTG)and evaluate its safety and *** We collected the relevant data of 77 patients who underwent TLTG at the Fourth Hospital of Hebei Medical University from October 2021 to January *** them,35 cases were treated with DTR,and the remaining 42 cases were treated with traditional *** 1:1 propensity score matching,the cases were grouped into 31 cases per group,with evenly distributed *** clinical characteristics and short-and long-term clinical outcomes of the two groups were statistically *** The two groups showed no significant differences in basic data,intraoperative blood loss,number of lymph node dissections,first defecation time after operation,postoperative hospital stay,postoperative complications,and laboratory examination results on the 1st,3rd,and 5th days after *** operation time of the DTR group was longer than that of the RY group[(307.58±65.14)min vs(272.45±62.09)min,P=0.016],but the first intake of liquid food in the DTR group was shorter than that in the RY group[(4.45±1.18)d vs(6.0±5.18)d,P=0.028].The incidence of reflux heartburn(Visick grade)and postoperative gallbladder disease in the DTR group was lower than that in the RY group(P=0.033 and P=0.038).Although there was no significant difference in bod

关键词： Gastric cancer Jejunal interposition double-tract reconstruction Roux-en-Y reconstruction Laparoscope

基于ESO的机械弹性电动轮式车辆稳定性控制

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吉林大学学报（工学版） 2024年第1期54卷 44-54页

作者：赵又群林涛林棻沈峘南京航空航天大学能源与动力学院南京210016

针对机械弹性电动轮(MEEW)式车辆的稳定性控制问题,考虑到车辆在实际行驶时存在的一些MEEW内部摄动和外部干扰,建立了存在非线性干扰项的2自由度车辆模型。基于上述模型对整车进行稳定性分层控制,在上层中分别设计了基于扩张状态观测器(... 详细信息

针对机械弹性电动轮(MEEW)式车辆的稳定性控制问题,考虑到车辆在实际行驶时存在的一些MEEW内部摄动和外部干扰,建立了存在非线性干扰项的2自由度车辆模型。基于上述模型对整车进行稳定性分层控制,在上层中分别设计了基于扩张状态观测器(ESO)的横摆角速度和质心侧偏角滑模控制器。通过ESO对非线性干扰项进行实时的观测和补偿。依据β-β相平面对车辆的稳定性区域进行划分,并基于此对上述两个控制器进行平滑切换。在下层控制器中,基于二次规划方法进行转矩分配。仿真实验结果表明:在考虑干扰的情况下,本文横摆稳定性控制器能够很好地控制匹配MEEW的分布式驱动电动车的稳定性。

关键词：扩张状态观测器机械弹性电动轮横摆稳定性控制非线性干扰项滑模控制

维普期刊数据库博看期刊

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基于多特征融合的点云配准算法

兰州大学学报（自然科学版） 2024年第4期60卷 509-515页

作者：赵夫群黄鹤西安财经大学信息学院西安710100

针对目前点云配准算法精度较低、计算复杂度较高的问题,提出一种基于多特征融合的点云配准算法.提取点云的法向角度、点及其邻域点的投影距离、曲率以及欧氏距离方差,通过对其融合来提取待配准点云的特征点.利用基于高斯概率模型的迭代... 详细信息

针对目前点云配准算法精度较低、计算复杂度较高的问题,提出一种基于多特征融合的点云配准算法.提取点云的法向角度、点及其邻域点的投影距离、曲率以及欧氏距离方差,通过对其融合来提取待配准点云的特征点.利用基于高斯概率模型的迭代最近点算法对特征点集进行配准,实现噪声点云的精确配准.对Cup、Bunny公共点云数据以及文物点云数据模型进行配准实验.结果表明,提出的算法相比已有算法的精度提升约20%,耗时降低约25%.

关键词：点云配准多特征融合法向角度曲率概率迭代最近点

优化营商环境助推台企深耕发展的实证研究:基于浙江的调查

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台湾研究 2024年第3期 90-101页

作者：赵群杨开煌宁波大学科学技术学院系宁波大学浙江台湾研究院台湾铭传大学两岸研究中心中国台湾

浙江是全国台商投资最集聚的地区之一,2023年浙江将优化营商环境作为实现经济高质量发展的“一号改革工程”。为了厘清台商对浙江营商环境的认知感受和满意度,本研究从市场环境、政务环境、法治政策环境和人文环境等维度建构营商环境评... 详细信息

浙江是全国台商投资最集聚的地区之一,2023年浙江将优化营商环境作为实现经济高质量发展的“一号改革工程”。为了厘清台商对浙江营商环境的认知感受和满意度,本研究从市场环境、政务环境、法治政策环境和人文环境等维度建构营商环境评价指标体系,并透过对246家在浙台企的问卷调查,实证分析台商对营商的环境的具体评价以及探讨营商环境优化与台商深耕祖国内地意愿的影响关系。研究结果表明:(一)台商对浙江营商环境的总体评价较好。相较而言,台商对政务环境、人文环境的满意度高于市场环境和法治政策环境;(二)优化营商环境与台企深耕祖国内地意愿存在部分显著影响关系。即优化营商环境并不能显著提升台商在浙江增资扩产的意愿,但是对台企数字化转型和推荐意愿(即推荐其他台胞赴陆创业)产生显著正向影响。可能原因:台企在祖国内地继续增资扩产的决策受到中美战略博弈、台海局势、供应链等多重因素共同影响。本研究根据台资企业发展基本现状,从财税支持、人才支撑、政策落实、加强融资、营造归属感等五项优化营商环境的具体路径。研究结果为客观掌握台企的发展动向并制定相关的政策预案,对于吸引和留住台企在祖国内地深耕发展提供实证支持。

关键词：营商环境台资企业满意度增资扩产深耕祖国内地意愿

World's Energy Transition and Chinese-style Modern Energy Revolution under Carbon Neutrality(Ⅰ)

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China Oil & Gas 2024年第2期31卷 3-13页

作者： Zou Caineng Xiong Bo Li Shixiang Ma Feng Pan Songqi Liu Hanlin Zhang Guosheng zhao qun Guan Chunxiao PetroChina Shenzhen New Energy Research Institute Research Institute of Petroleum Exploration&Development

Under global consensus on carbon neutrality and the intensification of regional conflicts,new energy has become the primary direction for various countries to achieve energy security and green *** by wind,solar,geothermal,hydrogen and stored energy,and controllable nuclear fusion,the technological and scale advantages of new energy are being continuously ***-cost wind,solar,and stored energy will support the global energy *** production and utilization of new energy enter a rapid development *** 2022,the average global consumption of new energy accounted for 18.2%,and it is expected to reach around 55%by *** distribution of the world's energy resources,consumption regions,technological development,per capita consumption,energy-saving fields,and carbon emissions is *** acceleration of low-carbon development in fossil fuels,the scale-up of renewable energy,and the intelligentization of energy management drives the rapid transition of global energy.

关键词： Transition strengthened acceleration

大埋深高水压煤矿突水危险性分析及水害监测预警指标构建

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煤炭与化工 2024年第7期47卷 61-65,70页

作者：赵群皖北煤电集团公司国家煤矿水害防治工程技术研究中心安徽宿州234000

针对大埋深高水压煤矿底板突水威胁,本文以恒源煤矿为研究对象,进行致灾机理及多要素监测预警理论研究,形成底板水害风险监测指标体系。利用熵权法及层次分析法,进行客观赋权及主观赋权,在此基础上进行组合赋权,得到各突水要素综合权重... 详细信息

针对大埋深高水压煤矿底板突水威胁,本文以恒源煤矿为研究对象,进行致灾机理及多要素监测预警理论研究,形成底板水害风险监测指标体系。利用熵权法及层次分析法,进行客观赋权及主观赋权,在此基础上进行组合赋权,得到各突水要素综合权重。研究方法及成果对水害监测平台的建设以及多元数据的采集,提供技术支撑及设计参考。

关键词：煤矿水害监测预警指标体系熵权法层次分析