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铁道学报 2000年第5期22卷 51-54页

作者：赵志程荫杭北方交通大学电子信息工程学院北京100044

通过对 UM71无绝缘轨道电路电气绝缘节分路灵敏度的分析 ,找出不满足标准分路灵敏度的区段 (即死区段 ) ,并计算其长度。

关键词：铁道信号轨道电路自动闭塞计算方法死区段

A new facile approach to N-alkylpyrroles from direct redox reaction of 4-hydroxy-L-proline with aldehydes

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中国科学：化学 2012年第2期42卷 202-204页

作者： ZOU ZhiQin DENG ZeJun YU XinHong ZHANG ManMan zhao SiHan LUO Ting yin Xin XU Hui WANG Wei School of Pharmacy Easy China University of Science ＆ Technology Shanghai 200237 China Department of Chemistry ＆ Chemical Biology University of New Mexico MSC03 2060 NM 87131 USA

An unprecedented acetic acid-catalyzed efficient access to N-alkylpyrroles from reaction of 4-hydroxy-L-proline with a variety of aldehydes has been achieved in good to excellent yields under mild reaction conditions.

关键词：氧化还原反应 L-脯氨酸羟基简便醛反应条件

大型敞口钢油罐结构风荷载试验与风力稳定分析

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华中科技大学学报（自然科学版） 2014年第7期42卷 66-71页

作者：林寅赵阳林巍浙江大学空间结构研究中心浙江杭州310058 浙江大学建筑设计研究院浙江杭州310027

对大型敞口钢油罐进行风荷载的风洞试验,获得结构表面的风荷载分布规律,并拟合成傅里叶公式,为设计应用提供方便.利用风洞试验获得的风荷载对大型敞口油罐进行稳定计算,研究了罐壁顶部包边角钢与结构风力稳定的关系,分析了初始几何缺陷... 详细信息

对大型敞口钢油罐进行风荷载的风洞试验,获得结构表面的风荷载分布规律,并拟合成傅里叶公式,为设计应用提供方便.利用风洞试验获得的风荷载对大型敞口油罐进行稳定计算,研究了罐壁顶部包边角钢与结构风力稳定的关系,分析了初始几何缺陷对结构非线性稳定性能的影响.结果表明:大型油罐这类高径比很小的低矮型圆柱结构的表面风荷载与普通圆柱结构的有明显差异;包边角钢可以加强油罐顶部的迎风面外刚度,提高结构屈曲的临界风荷载;敞口钢油罐的风力稳定性能对初始几何缺陷十分敏感,结构的稳定承载力随缺陷的增大显著降低.

关键词：大型钢油罐敞口油罐风荷载风洞试验稳定性圆柱薄壳

Novel multimodal analgesia regimen improves post-TACE pain in patients with hepatocellular carcinoma

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Hepatobiliary & Pancreatic Diseases International 2018年第6期17卷 510-516页

作者： Jian-Guo Guo Lu-Ping zhao Yue-Feng Rao yin-Ping Gao Xue-Jiao Guo Tan-Yang Zhou Zhi-ying Feng Jun-Hui Sun Xiao-Yang Lu Department of Pain Medicine The First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Key Laboratory of Precision Diagnosis and Treatment for Hepatobiliary and Pancreatic Tumor of Zhejiang Province Hangzhou 310003China Department of Pharmacy Dongyang People’s HospitalDongyang 322100China

Backgroud: Transarterial chemoembolization(TACE) is the primary palliative treatment for patients with unresectable hepatocellular carcinoma(HCC). However, it is often accompanied by postoperative pain which hinder patient recovery. This study was to examine whether preemptive parecoxib and sufentanilbased patient controlled analgesia(PCA) could improve the pain management in patients receiving TACE for inoperable HCC. Methods: From June to December 2016, 84 HCC patients undergoing TACE procedure were enrolled. Because of the willingness of the individuals, it is difficult to randomize the patients to different groups. We matched the patients’ age, gender and pain scores, and divided the patients into the multimodal group( n = 42) and control group( n = 42). Patients in the multimodal group received 40 mg of parecoxib, 30 min before TACE, followed by 48 h of sufentanil-based PCA. Patients in the control group received a routine analgesic regimen, i.e., 5 mg of dezocine during operation, and 100 mg of tramadol or equivalent intravenous opioid according to patient’s complaints and pain intensity. Postoperative pain intensity, percentage of patients as per the pain category, adverse reaction, duration of hospital stay, cost-effectiveness, and patient’s satisfaction were all taken into consideration when evaluated. Results: Compared to the control group, the visual analogue scale scores for pain intensity was significantly lower at 2, 4, 6, and 12 h(all P < 0.05) in the multimodal group and a noticeably lower prevalence of post-operative nausea and vomiting in the multimodal group(31.0% vs. 59.5%). Patient’s satisfaction in the multimodal group was also significantly higher than that in the control group(95.2% vs. 69.0%). No significant difference was observed in the duration of hospital stay between the two groups. Conclusion: Preemptive parecoxib and sufentanil-based multimodal analgesia regime is a safe, efficient and cost-effective regimen for postoperative pain con

关键词： Multimodal analgesia Transarterial chemoembolization Parecoxib Pain management

The authors acknowledge the financial support from the National Natural Science Foundation of China(project No.31971247).

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International Journal of Oral Science 2021年第2期13卷 148-155页

作者： Yan Wei Guixin Zhu Zifan zhao Chengcheng yin Qin zhao Hudi Xu Jinyang Wang Jinglun Zhang Xiaoxin Zhang Yufeng Zhang Haibin Xia The State Key Laboratory Breeding Base of Basic Science of Stomatology(Hubei-MOST)&Key Laboratory of Oral Biomedicine Ministry of Education School&Hospital of StomatologyWuhan UniversityWuhanChina Department of Oral Implantology School and Hospital of StomatologyWuhan UniversityWuhanChina

Mineralized tissue regeneration is an important and challenging part of the field of tissue engineering and *** present,autograft harvest procedures may cause secondary trauma to patients,while bone scaffold materials lack osteogenic activity,resulting in a limited *** with osteogenic induction growth factor can improve the osteoinductive performance of bone graft,but the explosive release of growth factor may also cause side *** this study,we innovatively used platelet-rich fibrin(PRF)-modified bone scaffolds(Bio-Oss®)to replace autograft,and used cytokine(BMP-2)to enhance ***,this mixture,which we named“Autograft Mimic(AGM)”,has multiple functions and advantages.(1)The fiber network provided by PRF binds the entire bone scaffold together,thereby shaping the bone grafts and maintaining the space of the defect area.(2)The sustained release of BMP-2 from bone graft promoted bone regeneration continuously.(3)AGM recruited bone marrow mesenchymal stem cells(BMSCs)and promote their proliferation,migration,and osteogenic ***,AGM developed in this study can improve osteogenesis,and provide new guidance for the development of clinical bone grafts.

关键词： sustained graft replace

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基于复合异质结构的近场热辐射调制器

工程热物理学报 2019年第10期40卷 2377-2382页

作者：阚银辉赵长颖上海交通大学工程热物理所

近场热辐射由于其能打破普朗克黑体辐射实现高效能量传输而得到广泛关注,已有的研究发现近场热辐射严格受限于高温物体和低温物体之间的距离,随着距离的增加热辐射传热效率将显著降低。本文提出一种基于六方氮化硼和石墨烯复合异质结构... 详细信息

近场热辐射由于其能打破普朗克黑体辐射实现高效能量传输而得到广泛关注,已有的研究发现近场热辐射严格受限于高温物体和低温物体之间的距离,随着距离的增加热辐射传热效率将显著降低。本文提出一种基于六方氮化硼和石墨烯复合异质结构的近场热辐射调制器,通过将该调制器放置于冷热源之间构成三物体系统可以增强光子隧穿效应从而调控近场热辐射传热量。进一步地,通过改变调制器的位置或结构可以对近场热辐射及相关温度进行主动调控。

关键词：近场热辐射二维材料等离激元声子极化激元

Ultraclean transfer of graphene by mechanically exfoliating polymer with modified crosslink density

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Nano Research 2024年第8期17卷 6795-6802页

作者： Qi Lu Jiawei Yang Chaofan Zhou zhaoning Hu Saiyu Bu Bingbing Guo Yixuan zhao Junhao Liao Mingpeng Shang Ge Chen Kaicheng Jia Jianbo yin Qiang Zeng Li Lin Zhongfan Liu College of Science China University of Petroleum(Beijing)Beijing 102249China School of Materials Science and Engineering Peking UniversityBeijing 100871China Center for Nanochemistry Beijing Science and Engineering Center for NanocarbonsBeijing National Laboratory for Molecular ScienceCollege of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871China Beijing Graphene Institute Beijing 100095China Faculty of Information Technology Beijing University of TechnologyBeijing 100124China Academy for Advanced Interdisciplinary Studies Peking UniversityBeijing 100871China Department of Electronics Peking UniversityBeijing 100871China Second Clinical Division National Engineering Laboratory for Digital and Material Technology of StomatologyPeking University School and Hospital of StomatologyBeijing 100081China

The transfer of graphene from metallic substrates onto application-specific substrates is usually inevitable for the applications of high-quality graphene films derived from chemical vapour deposition(CVD)*** used to support the graphene films during the transfer,the coating of the polymer would produce the surface contaminations and hinder the industrially compatible *** this work,through the thermal imidization of polyamide acid(PAA)to polyimide(PI)and tuning of the concentration of dangling chains,we achieved the ultraclean and crack-free transfer of graphene wafers with high electronic *** resulting contamination-free and hydrophilic surface also enabled the observed improved cell viability in a biomedical *** avoiding aqueous etching or the usage of strong bases,our proposed transfer method is industrially compatible for batch transfer of graphene films towards the real applications.

关键词： chemical vapour deposition(CVD)graphene films graphene transfer ultraclean transfer transfer medium crosslink density cell viability assay

船舶电力推进系统电力负荷混沌特性分析及预测

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大连海事大学学报 2008年第2期34卷 126-128页

作者：赵敏樊印海大连海事大学自动化与电气工程学院辽宁大连116026

为实现船舶电力推进系统功耗的最优控制,提高船舶运行的经济性,建立了基于正则化的电力负荷混沌局域预测模型.运用相空间重构理论对船舶电力推进系统电力负荷进行单变量时间序列相空间重构,计算吸引子的Lyapunov指数,验证船舶电力推进... 详细信息

为实现船舶电力推进系统功耗的最优控制,提高船舶运行的经济性,建立了基于正则化的电力负荷混沌局域预测模型.运用相空间重构理论对船舶电力推进系统电力负荷进行单变量时间序列相空间重构,计算吸引子的Lyapunov指数,验证船舶电力推进系统电力负荷具有混沌特性,进而构建更为精准的由船舶电力负荷及其影响因素构成的多变量时间序列相空间.实验结果表明,该预测模型是有效的,且具有较高的预测精度.

关键词：船舶电力推进系统电力负荷混沌特性

ADAR1 Inhibits Macrophage Apoptosis and Alleviates Sepsis-induced Liver Injury Through miR-122/BCL2A1 Signaling

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Journal of Clinical and Translational Hepatology 2024年第2期12卷 134-150页

作者： Shanshou Liu Jiangang Xie Chujun Duan Xiaojun zhao Zhusheng Feng Zheng Dai Xu Luo Yu Li Minghe Yang Ran Zhuang Junjie Li Wen yin Emergency Department Xijing HospitalFourth Military Medical UniversityXi’anShaanxiChina Emergency Department Tangdu HospitalFourth Military Medical UniversityXi’anShaanxiChina Third Student Brigade School of Basic Medical ScienceFourth Military Medical UniversityXi’anShaanxiChina Department of Immunology Fourth Military Medical UniversityXi’anShaanxiChina

apoptosis plays regulatory roles in the pathogenesis of immunosuppression and organ *** previously reported that adenosine deaminases acting on RNA-1(ADAR1)reduced intestinal and splenic inflammatory damage during ***,the roles and mechanism of ADAR1 in sepsis-induced liver injury remain ***:We performed transcriptome and single-cell RNA sequencing of peripheral blood mononuclear cells(PBMCs)from patients with sepsis to investigate the effects of ADAR1 on immune cell *** also employed a cecal ligation and puncture(CLP)sepsis mouse model to evaluate the roles of ADAR1 in sepsisinduced liver ***,we treated murine RAW 264.7 macrophages with lipopolysaccharide to explore the underlying ADAR1-mediated mechanisms in ***:PBMCs from patients with sepsis had obvious apoptotic morphological ***-cell RNA sequencing indicated that apoptosis-related pathways were enriched in monocytes,with significantly elevated ADAR1 and BCL2A1 expression in severe ***-induced septic mice had aggravated liver injury and Kupffer cell apoptosis that were largely alleviated by ADAR1 ***1 directly bound to premiR-122 to modulate miR-122 ***-122 was an upstream regulator of ***,ADAR1 also reduced macrophage apoptosis in mice with CLP-induced sepsis through the miR-122/BCL2A1 signaling pathway and protected against sepsis-induced liver ***:The findings show that ADAR1 alleviates macrophage apoptosis and sepsis-induced liver damage through the miR-122/BCL2A1 signaling *** study provides novel insights into the development of therapeutic interventions in sepsis.

关键词： Sepsis Macrophage ADAR1 microRNA122 BCL2A1 Apoptosis

1064 nm InGaAsP multi-junction laser power converters

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Journal of Semiconductors 2020年第6期41卷 39-43页

作者： Jiajing yin Yurun Sun Shuzhen Yu Yongming zhao Rongwei Li Jianrong Dong Key Laboratory of Nano Devices and Applications Suzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of SciencesSuzhou 215123China Nano Science and Technology Institute University of Science and Technology of ChinaHefei 230026China

Laser photovoltaic devices converting 1064 nm light energy into electric energy present a promising prospect in wireless energy transmission due to the commercial availability of high power 1064 nm lasers with very small divergence. Besides their high conversion efficiency, a high output voltage is also expected in a laser energy transmission system. Meanwhile,1064 nm InGaAsP multi-junction laser power converters have been developed using p^+-InGaAs/n^+-InGaAs tunnel junctions to connect sub-cells in series to obtain a high output voltage. The triple-junction laser power converter structures are grown on p-type InP substrates by metal-organic chemical vapor deposition(MOCVD), and InGaAsP laser power converters are fabricated by conventional photovoltaic device processing. The room-temperature I–V measurements show that the 1 × 1 cm^2 triplejunction InGaAsP laser power converters demonstrate a conversion efficiency of 32.6% at a power density of 1.1 W/cm^2, with an open-circuit voltage of 2.16 V and a fill factor of 0.74. In this paper, the characteristics of the laser power converters are analyzed and ways to improve the conversion efficiency are discussed.

关键词： InGaAsP multi-junction laser power converter conversion efficiency