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Clinical outcome and prognostic factors of T4N0M0 colon cancer after R0 resection:A retrospective study

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 1869-1877页

作者： Bang Liu zhao-xiong Zhang Xin-Yang Nie Wei-Lin Sun Yong-Jia Yan Wei-Hua Fu Department of General Surgery Tianjin Medical University General HospitalTianjin Medical UniversityTianjin 300052China

BACKGROUND Paradoxically,patients with T4N0M0(stage II,no lymph node metastasis)colon cancer have a worse prognosis than those with T2N1-2M0(stage III).However,no previous report has addressed this issue.AIM To screen prognostic risk factors for T4N0M0 colon cancer and construct a prognostic nomogram model for these patients.METHODS Two hundred patients with T4N0M0 colon cancer were treated at Tianjin Medical University General Hospital between January 2017 and December 2021,of which 112 patients were assigned to the training cohort,and the remaining 88 patients were assigned to the validation cohort.Differences between the training and validation groups were analyzed.The training cohort was subjected to multi-variate analysis to select prognostic risk factors for T4N0M0 colon cancer,followed by the construction of a nomogram model.RESULTS The 3-year overall survival(OS)rates were 86.2%and 74.4%for the training and validation cohorts,respectively.Enterostomy(P=0.000),T stage(P=0.001),right hemicolon(P=0.025),irregular review(P=0.040),and carbohydrate antigen 199(CA199)(P=0.011)were independent risk factors of OS in patients with T4N0M0 colon cancer.A nomogram model with good concordance and accuracy was constructed.CONCLUSION Enterostomy,T stage,right hemicolon,irregular review,and CA199 were independent risk factors for OS in patients with T4N0M0 colon cancer.The nomogram model exhibited good agreement and accuracy.

关键词： T4N0M0 colon cancer Prognosis Multivariate analysis Nomogram Colon cancer

Heavy ion energy influence on multiple-cell upsets in small sensitive volumes:from standard to high energies

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Nuclear Science and Techniques 2024年第5期35卷 109-121页

作者： Yang Jiao Li-Hua Mo Jin-Hu Yang Yu-Zhu Liu Ya-Nan Yin Liang Wang Qi-Yu Chen Xiao-Yu Yan Shi-Wei zhao Bo Li You-Mei Sun Pei-xiong zhao Jie Liu Institute of Modern Physics Chinese Academy of ScienceLanzhou 730000China University of Chinese Academy of Science Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China China Electronics Technology Group Corporation No.58 Research Institute Wuxi 214000China Beijing Microelectronics Technology Institute Beijing 100084China Institute of Microelectronics Chinese Academy of SciencesBeijing 100029China Key Laboratory of Science and Technology on Silicon Devices Chinese Academy of SciencesBeijing 100029China

The 28 nm process has a high cost-performance ratio and has gradually become the standard for the field of radiation-hardened devices.However,owing to the minimum physical gate length of only 35 nm,the physical area of a standard 6T SRAM unit is approximately 0.16μm^(2),resulting in a significant enhancement of multi-cell charge-sharing effects.Multiple-cell upsets(MCUs)have become the primary physical mechanism behind single-event upsets(SEUs)in advanced nanometer node devices.The range of ionization track effects increases with higher ion energies,and spacecraft in orbit primarily experience SEUs caused by high-energy ions.However,ground accelerator experiments have mainly obtained low-energy ion irradiation data.Therefore,the impact of ion energy on the SEU cross section,charge collection mechanisms,and MCU patterns and quantities in advanced nanometer devices remains unclear.In this study,based on the experimental platform of the Heavy Ion Research Facility in Lanzhou,low-and high-energy heavy-ion beams were used to study the SEUs of 28 nm SRAM devices.The influence of ion energy on the charge collection processes of small-sensitive-volume devices,MCU patterns,and upset cross sections was obtained,and the applicable range of the inverse cosine law was clarified.The findings of this study are an important guide for the accurate evaluation of SEUs in advanced nanometer devices and for the development of radiation-hardening techniques.

关键词： 28 nm static random access memory(SRAM) Energy effects Heavy ion Multiple-cell upset(MCU) Charge collection Inverse cosine law

Manganese oxide and derivative-modified materials in advanced oxidation processes:A review of modification enhancement and activation mechanisms

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Chinese Chemical Letters 2024年第3期35卷 40-51页

作者： Si Sun Shuang Song Shuai Yang Yong-Li He Yang Shi Peng Zhou zhao-kun xiong Yang Liu Heng Zhang Ye Du Chuan-Shu He Bo Lai State Key Laboratory of Hydraulics and Mountain River Engineering College of Architecture and EnvironmentSichuan UniversityChengdu 610065China Sino-German Centre for Water and Health Research Sichuan UniversityChengdu 610065China Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaSichuanChengdu 610054China

Manganese oxides(MNO_(x)),as low-toxicity and high-abundance catalysts,have been demonstrated to hold great promise for application in advanced oxidation processes(AOPs).However,further application of this material is restricted due to its unsatisfactory oxidant activation efficiency.Fortunately,recently remarkable research on deep activation mechanisms and modification of MNO_(x)have been undertaken to improve its reactivity.Herein,modification enhancement mechanisms of MNO_(x)to efficiently degrade various organic contaminants were discussed and highlighted,including metal doping,coupling with other metal oxides,composite with carbonaceous material,and compounding with other support.The activation mechanisms of different MNO_(x)and derivative-modified material(such as doped MNO_(x),metal oxide-MNO_(x)hybrids,and MNO_(x)-carbonaceous material hybrids)were summarized in great details,which was specifically categorized into both radical and non-radical pathways.The effects of pH,inorganic ions,and natural organic matter on degradation reactions are also discussed.Finally,future research directions and perspectives are presented to provide a clear interpretation on the MNO_(x)initiated AOPs.

关键词： Manganese oxide Derivative-modified materials Modification enhancement mechanisms Advanced oxidation process Activation mechanism

弹性支承块轨道结构病害对钢轨竖向位移影响研究

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城市轨道交通研究 2024年第S1期27卷 37-41页

作者：赵雄上海地铁维护保障有限公司工务分公司上海200233

[目的]弹性支承块轨道结构因其具有较强的减振降噪特性,在城市轨道交通中被广泛应用。但弹性支承块轨道结构病害对钢轨竖向位移影响较大,需对其进行研究,以有效整治该类病害。[方法]弹性支承块轨道结构主要病害为支承块空吊和扣件失效... 详细信息

[目的]弹性支承块轨道结构因其具有较强的减振降噪特性,在城市轨道交通中被广泛应用。但弹性支承块轨道结构病害对钢轨竖向位移影响较大,需对其进行研究,以有效整治该类病害。[方法]弹性支承块轨道结构主要病害为支承块空吊和扣件失效。基于上海轨道交通8号线弹性支承块轨道结构,建立了弹性支承块轨道静力学模型,分析了无缝线路和有缝线路轨道在列车静荷载下支承块空吊、扣件失效对钢轨竖向位移的影响。[结果及结论]支承块空吊病害会对钢轨竖向位移产生较大影响。对于无缝线路,无支承块空吊病害时的钢轨竖向位移为1.441 mm;对于有缝线路,无支承块空吊病害时的钢轨竖向位移为1.530 mm。发生支承块空吊时,随着支承块空吊量的增加,钢轨竖向最大位移先增加后趋于稳定。在扣件完全失效情况下,钢轨竖向位移会随着失效扣件套数的增加而成倍增加,有缝线路钢轨竖向位移比无缝线路的大0.056~1.186 mm。扣件刚度折减越少,对其他位置钢轨竖向位移影响越小。

关键词：城市轨道交通轨道结构支承块空吊扣件失效钢轨竖向位移

马克思主义理论与中华优秀传统文化内核一致性初探——“第二个结合”的理论意义、内在逻辑与路径探索

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价格理论与实践 2024年第1期 11-16页

作者：李钢熊昭中国社会科学院工业经济研究所/中国社会科学院大学应用经济学院中国社会科学院大学应用经济学院

马克思主义和中华优秀传统文化存在众多相互融通之处:在哲学领域,马克思主义与中华优秀传统文化都将唯物论作为基本内核;农业是工业革命以前最重要的实体经济,中国传统经济思想秉承“重农抑商”观念,认为唯有从事具体的农业、手工业劳... 详细信息

马克思主义和中华优秀传统文化存在众多相互融通之处:在哲学领域,马克思主义与中华优秀传统文化都将唯物论作为基本内核;农业是工业革命以前最重要的实体经济,中国传统经济思想秉承“重农抑商”观念,认为唯有从事具体的农业、手工业劳动才能创造价值,这与马克思主义政治经济学理论基石劳动价值论相一致;科学社会主义和中华优秀传统文化在价值观上异曲同工,都体现了对普通民众的尊重与关照,坚定地站在人民一边。因此,发展马克思主义、推动马克思主义中国化和弘扬中华优秀传统文化可以在新时代中国特色社会主义现代化建设之中得以实现。

关键词：马克思主义中华优秀传统文化第二个结合

Optimization design and test of rice plug seedling transplanting mechanism of planetary gear train with incomplete eccentric circular gear and non-circular gears

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International Journal of Agricultural and Biological Engineering 2017年第6期10卷 43-55页

作者： Ye Bingliang Yi Weiming Yu Gaohong Gao Yang zhao xiong Faculty of Mechanical Engineering and Automation Zhejiang Sci-Tech UniversityHangzhou 310018China Zhejiang Province Key Laboratory of Transplanting Equipment and Technology Hangzhou 310018China

In order to solve the problem of the high-speed mechanized transplanting of rice plug seedlings,the design requirements of transplanting mechanism for rice plug seedlings were analyzed and a kind of rice plug seedling transplanting mechanism of planetary gear train based on the drive with incomplete eccentric circular gear and non-circular gears was designed innovatively.The laboratory kinematics was examined.The working principle of the transplanting mechanism for rice plug seedlings was studied,kinematics analysis of the transplanting mechanism was carried out and its kinematic model was set up.A human-computer interaction optimization method was used to optimize the parameters of the transplanting mechanism.The computer aided analysis and optimization software of the transplanting mechanism based on Visual Basic 6.0 was developed.Through analyzing the influence of design variables on the optimization objectives of the transplanting mechanism,a set of parameters of the transplanting mechanism which meet the requirements of transplanting trajectory and posture for transplanting rice seedlings were obtained by means of human-computer interaction.The structure of the transplanting mechanism was designed according to this set of parameters,and its virtual prototype and physical prototype were set up and manufactured,respectively.The kinematic simulation test and high-speed photography kinematic test of the transplanting mechanism were conducted to obtain its kinematic performances,such as transplanting trajectory and posture.The results of bench test,simulation analysis and theoretical analysis were almost in agreement,which verified the correctness of the theoretical model and design results of the transplanting mechanism,indicating that the optimized transplanting mechanism can satisfy the requirements of transplanting rice seedlings and be applied in the rice plug seedling transplanter.

关键词： plug seedling transplanting mechanism incomplete eccentric circular gear non-circular gear planetary gear train optimization design

Review of advanced oxidation processes for treating hospital sewage to achieve decontamination and disinfection

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Chinese Chemical Letters 2024年第1期35卷 140-152页

作者： Si-Ying Yu Zhi-Hui Xie Xiaoyu Wu Yun-Zhe Zheng Yang Shi zhao-Kun xiong Peng Zhou Yang Liu Chuan-Shu He Zhi-Cheng Pan Kai-Jun Wang Bo Lai State Key Laboratory of Hydraulics and Mountain River Engineering College of Architecture and EnvironmentSichuan UniversityChengdu 610065China Sino-German Centre for Water and Health Research Sichuan UniversityChengdu 610065China State Key Joint Laboratory of Environment Simulation and Pollution Control School of EnvironmentTsinghua UniversityBeijing 100084China Water Safety and Water Pollution Control Engineering Technology Research Center in Sichuan Province Haitian Water GroupChengdu 610041China

Hospital sewage contains various harmful pharmaceutical contaminants(e.g.,antibiotics,anti-inflammatory agents,and painkillers)and pathogens(e.g.,bacteria,viruses,and parasites),whose direct discharge into the environment will induce diseases and pose a powerful threat to human health and safety,and environmental ecology.In recent years,advanced oxidation processes(AOPs),particularly photocatalysis,electrocatalysis,and ozone catalysis have been developed as widespread and effective techniques for hospital sewage treatments.However,there is a lack of systematic comparison and review of the prior studies on hospital sewage treatment using AOPs systems.This review elaborates on the mechanisms,removal efficiencies,and advantages/disadvantages of these AOPs systems for hospital wastewater decontamination and disinfection.Meanwhile,some novel and potential technologies such as photo-electrocatalysis,electro-peroxone,Fenton/Fenton-like,and piezoelectric catalysis are also included and summarized.Moreover,we further summarize and compare the capacity of these AOPs to treat the actual hospital wastewater under the impact of the water matrix and pH,and estimate the economic cost of these technologies for practical application.Finally,the future development directions of AOPs for hospital wastewater decontamination and disinfection have been prospected.Overall,this study provides a comparison and overview of these AOP systems in an attempt to raise extensive concerns about hospital wastewater decontamination and disinfection technologies and guide researchers to discover the future directions of technologies optimization,which would be a crucial step forward in the field of hospital sewage treatment.

关键词： Hospital sewage treatment Advanced oxidation processes Pharmaceutical contaminants Disinfection Decontamination

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振动式大葱分苗装置设计与试验

农机化研究 2024年第7期46卷 164-169,177页

作者：吴磊赵雄代丽徐亚丹浙江理工大学机械与自动控制学院杭州310018 浙江省种植装备技术重点试验室杭州310018 杭州职业技术学院杭州310018

为了解决大葱秧苗移栽机需人工分苗的问题设计了一种振动式大葱分苗装置,原理是利用斜抛运动的原理,通过曲柄摇杆机构施加一个振动,将堆叠的大葱秧苗分离开来。首先,分析大葱秧苗状态和运动,确定了锯齿板高为10.6mm、长为21.2mm,曲柄半... 详细信息

为了解决大葱秧苗移栽机需人工分苗的问题设计了一种振动式大葱分苗装置,原理是利用斜抛运动的原理,通过曲柄摇杆机构施加一个振动,将堆叠的大葱秧苗分离开来。首先,分析大葱秧苗状态和运动,确定了锯齿板高为10.6mm、长为21.2mm,曲柄半径为13.4mm;其次,对大葱秧苗进行运动仿真,得到不同因素对分苗效果的影响范围;最后,以分苗率为评价指标,以电机转速、摇杆长度、单次投苗数量为试验因素进行三因素三水平的正交试验,确定较优的参数组合。用Design-Expert软件分析得到:在连杆长度为373.943mm、单次投苗数量为15棵、电机转速为368.027r/min时,分苗率达到最佳为78.20%,满足工作要求。

关键词：大葱分苗曲柄摇杆振动运动分析

当代中国贫困治理的伦理基础、基本模式与实践特征

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深圳社会科学 2024年第1期7卷 33-42页

作者：易申波赵雄南昌航空大学文法学院江西南昌330063 江西省人事考试中心江西南昌330029

从伦理基础、基本模式与实践特征三个方面阐述当代中国贫困治理的历程及成功经验,认为当代中国贫困治理的成功,不仅是中国独特制度优势的体现,而且其中提炼的一些贫困治理经验,可以为广大发展中国家的贫困治理提供借鉴。在贫困治理的伦... 详细信息

从伦理基础、基本模式与实践特征三个方面阐述当代中国贫困治理的历程及成功经验,认为当代中国贫困治理的成功,不仅是中国独特制度优势的体现,而且其中提炼的一些贫困治理经验,可以为广大发展中国家的贫困治理提供借鉴。在贫困治理的伦理基础方面,革命年代为了发动穷苦大众投身革命,赋予他们极高的政治地位,导致了“穷光荣”文化传统的形成,“越贫穷越光荣”的社会文化心理延迟了脱贫的紧迫性,在一定程度上使得计划经济时代的中国减贫事业难以达到应有的发展速度;改革开放以来,贫困与道德的脱钩、经济发展与社会主义本质的链接使得全面脱贫变得必要且可能。在贫困治理的基本模式方面,政府主导贫困治理的政策制定、资源分配及项目实施,同时积极发挥市场作为资源配置基本机制的作用,创新市场化扶贫方式,由此形成贫困治理的“政府主导的市场模式”。在实践方面,社会协同和公共参与既是现代化贫困治理体系的必然要求与重要特征,也是当代中国贫困治理成功的深层原因。全面脱贫后,巩固脱贫成果、防止脱贫后返贫的任务仍然十分艰巨,仍然面临着持续有效治理相对贫困等多元贫困问题的严峻挑战,必须进一步探索具有开放性、整体性、可持续性的参与式贫困治理体系,进一步完善贫困治理生态,早日实现全面建成社会主义现代化强国的伟大目标。

关键词：贫困治理贫困的去道德化政府主导市场机制公共参与