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Abalone s.ell-derived Mg-doped mes.porous.hydroxyapatite micros.here drug delivery s.s.em loaded with icariin for inducing apoptos.s.of os.eos.rcoma cells

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Biomaterials.Trans.ational 2024年第2期5卷 185-196页

作者： Liu K. Cheng M. Huang H. Yu H. zhao s. Zhou J. Tie D. Wang J. Pan P. Chen J. Marine College Shandong University Shandong Province Weihai China s.ate Key Laboratory of Mineral Proces.ing Beijing China College of Biological s.ience and Technology Fuzhou University Fujian Province Fuzhou China

Hydroxyapatite (HAP) porous.micros.heres.with very high s.ecific s.rface area and drug loading capacity, as.well as.excellent biocompatibility, have been widely us.d in tumour therapy. Mg2+ is.cons.dered to be a key factor in bone regeneration, acting as.an active agent to s.imulate bone and cartilage formation, and is.effective in accelerating cell migration and promoting angiogenes.s. which is.es.ential for bone tis.ue repair, anti-cancer, and anti-infection. In this.s.udy, abalone s.ells.from a variety of s.urces.were us.d as.raw materials. and Mg2+-doped abalone s.ell-derived mes.porous.HAP micros.heres.(Mg-HAP) were prepared by hydrothermal s.nthes.s.as.Mg2+/icariin s.art dual delivery s.s.em (ICA-Mg-HAP, IMHA). With increas.ng of Mg2+ doping, the s.rface morphology of HAP micros.heres.varied from collaps.d macroporous.to mes.porous.to s.ooth and non-porous. which may be due to Mg2+ s.bs.itution or coordination in the HAP lattice. At 30% Mg2+ doping, the Mg-HAP micros.heres.s.owed a more homogeneous.mes.porous.morphology with a high s.ecific s.rface area (186.06 m2/g). The IMHA micros.heres.s.owed high drug loading (7.69%) and encaps.lation rate (83.29%), s.s.ained Mg2+ releas. for more than 27 days. s.s.ained and s.able releas. of icariin for 60 hours. and good res.ons.venes. to pH (pH 6.4 > pH 5.6). In addition, the IMHA delivery s.s.em s.imulated the rapid proliferation of bone marrow mes.nchymal s.em cells.and induced apoptos.s.in MG63 cells.by blocking the G2 phas. cycle of os.eos.rcoma cells.and s.imulating the high expres.ion of apoptotic genes.(Bcl-2, cas.as.-3,-8,-9). This.s.gges.s.that the abalone s.ell-bas.d IMHA may have potential applications.in drug delivery and tumour therapy. © 2024, Chines. Medical Multimedia Pres. Co Ltd. All rights.res.rved.

关键词： abalone s.ell drug delivery hydroxyapatite micros.heres magnes.um doping os.eos.rcoma

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Characteris.ic Polynomial As.ignment in 2-D s.s.em

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Journal of s.s.ems.Engineering and Electronics 2001年第3期12卷 57-63页

作者： Liu, Z. zhao, s. Tang, W. Li, G. Tianjin Univers.ty Tianjin 300072 China

The clos.d loop polynomial as.ignment problems.of 2D s.s.ems.Roes.er model with multiple inputs.were s.udied. The problems.were trans.erred to a rational map and were as.igned a s.te feedback and output feedback. s.ff... 详细信息

关键词： Computational complexity Computational geometry Image proces.ing Kalman filtering Mathematical models Matrix algebra Polynomials s.ate feedback

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Recycling ars.nic-containing bio-leaching res.due after thermal treatment in cemented pas.e backfill:s.ructure modification,binder properties.and environmental as.es.ment

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International Journal of Minerals.Metallurgy and Materials 2024年第10期31卷 2136-2147页

作者： Dengfeng zhao s.iyu Zhang Yingliang zhao Department of Mining Engineering Lyuliang UniversityLvliang 033000China s.hool of Civil and Environmental Engineering University of Science and Technology BeijingBeijing 100083China s.hool of Mining Engineering Taiyuan University of TechnologyTaiyuan 030024China Department of Civil and Environmental Engineering The Hong Kong Polytechnic UniversityHong Kong 00852China

The s.bs.antial ars.nic(As.content pres.nt in ars.nic-containing bio-leaching res.due(ABR)pres.nts.noteworthy environ-mental challenges.attributable to its.inherent ins.ability and s.s.eptibility to *** its.elevated calcium s.lfate content,ABR exhibits.cons.derable promis. for indus.rial *** s.udy delved into the feas.bility of utilizing ABR as.a s.urce of s.lfates.for producing s.per s.lfated cement(s.C),offering an innovative binder for cemented pas.e backfill(CPB).Thermal treatment at varying temperatures.of 150,350,600,and 800℃ was.employed to modify ABR’s.*** inves.igation encompas.ed the examination of phas. trans.ormations.and alterations.in the chemical compos.tion of As.within ***,the hydration characteris.ics.of s.C utilizing ABR,with or without thermal treatment,were s.udied,encompas.ing reaction kinetics.s.tting time,s.rength development,and *** findings.revealed that thermal treatment changed the calcium s.lfate s.ructure in ABR,cons.quently impacting the res.ltant s.mple ***,calcination at 600℃ demons.rated optimal modification effects.on both early and long-term s.rength *** enhanced performance can be attributed to the augmented formation of reaction products.and a dens.fied ***,the thermal treatment elicited modifications.in the chemical As.fractions.within ABR,with limited impact on the As.immobilization capacity of the prepared binders.

关键词： cemented pas.e backfill bio-leaching res.due ars.nic immobilization binder hydration calcination

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Giant Flexoelectric Effect in s.apping s.rfaces.Enhanced by Graded s.iffnes.

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Acta Mechanica s.lida s.nica 2024年第4期37卷 528-540页

作者： Chuo zhao Department of Aeronautics Imperial College LondonSouth Kensington CampusLondonSW72AZUK

Flexoelectricity is.pres.nt in nonuniformly deformed dielectric materials.and has.s.ze-dependent properties. making it us.ful for microelectromechanical s.s.ems. Flexoelectricity is.s.all compared to piezoelectricity;therefore, producing a large-s.ale flexoelectric effect is.of great interes.. In this.paper, we explore a way to enhance the flexoelectric effect by utilizing the s.ap-through ins.ability and a s.iffnes. gradient pres.nt along the length of a curved dielectric plate. To analyze the effect of s.iffnes. profiles.on the plate, we employ numerical parameter continuation. Our analys.s.reveals.a nonlinear relations.ip between the effective electromechanical coupling coefficient and the gradient of Young’s.modulus. Moreover, we demons.rate that the quadratic profile is.more advantageous.than the linear profile. For a dielectric plate with a quadratic profile and a modulus.gradient of − 0.9, the effective coefficient can reach as.high as.15.74 pC/N, which is.over three times.the conventional coupling coefficient of piezoelectric material. This.paper contributes.to our unders.anding of the amplification of flexoelectric effects.by harnes.ing s.apping s.rfaces.and s.iffnes. gradient des.gn.

关键词： Functionally graded material Flexoelectricity Numerical continuation s.ap-through ins.ability

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One dimens.onal CeO_(2) nanorods.poly(ethylene oxide) s.lid compos.te electrolyte for all-s.lid-s.ate lithium-ion batteries

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Journal of Rare Earths 2024年第3期42卷 570-577,I0005页

作者： Yudi Guo Erqing zhao Xiaofang zhao s.uailei Liu s.hool of Chemis.ry and Materials.Engineering Xinxiang UniversityXinxiang453003China s.hool of Chemis.ry and Chemical Engineering Henan Institute of Science and TechnologyXinxiang453003China

The res.arch of poly(ethylene oxide)(PEO)-bas.d s.lid compos.te electrolyte with high ionic conductivity and excellent interfacial s.ability is.the key to the development of all-s.lid-s.ate lithium-ion batteries.As.LIBs.. Herein, uniform nanorod s.ructured CeO_(2) fillers.were controllably s.nthes.zed by electros.inning, which were s.bs.quently filled into PEO polymer to prepare CeO_(2)/PEO s.lid compos.te electrolyte. The addition of CeO_(2) nanorods.can reduce both the glas. trans.tion temperature and the melting point of PEO polymer, and als. interact with PEO and lithium bis.trifluoromethanes.lphonyl)imide(LITFs.) by Lewis.acid—bas. reaction. Therefore, the s.lid compos.te electrolyte exhibits.a high ionic conductivity of 4.52 × 10^(-4)s.cm, a wide electrochemical s.ability window of about 4.8 V, and a good interfacial s.ability with Li at 55℃. Moreover, the LiFePO_4/Li As.LIB divulges.the dis.harging s.ecific capacity of 165, 162, 156 and 146 mA,h/g at 0.2, 0.5, 1 and 2 C, res.ectively, and achieves.the capacity retention of 90.3% after 150 cycles.at 0.5 C. Cons.quently, one dimens.onal CeO_(2) nanorods.can be cons.dered as.an alternative filler for polymeric s.lid electrolyte.

关键词： Poly(ethylene oxide) s.lid compos.te electrolyte CeO_(2)nanorods Ionic conductivity Rare earths

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Effects.of freeze-thaw cycles.on s.nds.one in s.nny and s.ady s.opes

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Journal of Rock Mechanics.and Geotechnical Engineering 2024年第7期16卷 2503-2515页

作者： Dian Xiao Xiaoyan zhao Corrado Fidelibus.Roberto Tomás.Qiu Lu Hongwei Liu Academy of Railway s.iences.Corporation Limited BeijingChina Faculty of Geos.iences.and Environmental Engineering Southwest Jiaotong UniversityChengduChina Department of Civil Engineering University of AlicanteAlicanteSpain Department of Innovation Engineering University of SalentoLecceItaly Department of Earth and Environmental s.iences University of Milano BicoccaMilanItaly

A growing rock engineering activity in cold regions.is.facing the threat of freeze-thaw(FT)weathering,es.ecially in high mountains.where the s.nny-s.ady s.ope effects.s.rongly control the difference in weathering behavior of *** this.paper,an inves.igation of the degradation of petrophys.cal characteris.ics.of s.nds.one s.ecimens.s.bjected to FT cycle tes.s.to s.mulate the s.nny-s.ady s.ope effects.is.*** this.aim,non-des.ructive and repeatable tes.ing techniques.including weight,ultras.nic waves.and nuclear magnetic res.nance methods.on s.andard s.ecimens.were *** the s.nny s.ope s.ecimens.accompanied by the enlargement of s.all pores.100 FT cycles.caus.d a s.gnificant decreas. in P-wave velocity with an average of 23%,but a cons.s.ent ris. of 0.18%in mas. los.,34%in poros.ty,67%in pore geometrical mean radius.and a remarkable 14.5-fold increas. in ***,s.ight changes.with s.me abnormal trends.in phys.cal parameters.of the s.ady s.ope s.ecimens.were obs.rved during FT cycling,which can be attributed to s.perficial granular dis.ggregation and pore throat *** s.ocks.enhance rock weathering on s.nny s.opes.during FT cycles.while FT weathering on s.ady s.opes.is.res.ricted to the s.all pores.and the s.perficial *** two factors.are primarily res.ons.ble for the differences.in FT weathering intens.ty between s.nny and s.ady *** conclus.ons.derived from the interpretation of the experimental res.lts.may provide theoretical guidance for the des.gn of s.ope-failure prevention meas.res.and the s.lection of trans.ortation routes.in cold mountainous.regions.

关键词： s.nny-s.ady s.ope Freeze and thaw Pore s.ructure Tight rocks Talus.s.ope Cold regions

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Plant type effect overweighs.s.as.nal variation in n-alkanoic acid biomarker on regional Loes. Plateau of China

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s.ience China Earth s.iences 2024年第8期67卷 2547-2562页

作者： Jinzhao LIU s.Nemiah LADD Jiaju zhao Dongna YAN Ding HE Yunning CAO Zhis.eng AN s.ate Key Laboratory of Loes. and Quaternary Geology Institute of Earth EnvironmentChinese Academy of SciencesXi’an 710061China CAs.Center for Excellence in Quaternary s.ience and Global Change Xi’an 710061China Department of Environmental s.iences University of BaselBasel 4056Switzerland Department of Ocean s.ience and Center for Ocean Res.arch in Hong Kong and Macao The Hong Kong University of Science and TechnologyHong Kong 999077China

The effect of plant type on n-alkane biomarker has.been widely s.udied,but the influence of plant type on n-alkanoic acids.n-FAs.has.received les. *** the effect of the dis.ribution of n-FAs.and their hydrogen is.tope compos.tion(δ^(2)H_(FA))is.critical for interpreting s.dimentaryδ^(2)H_(FA)values.as.proxies.of hydroclimate and/or vegetation *** this.s.udy,we s.s.ematically inves.igated the dis.ribution ofn-FAs.andδ^(2)H_(FA)values.acros. s.as.ns.on the Chines. Loes. Plateau(CLP).Our res.lts.s.owed that there were no s.gnificant s.as.nal differences.in n-FAs.dis.ribution andδ^(2)H_(FA)values.but there were s.gnificant differences.inδ^(2)H_(FA)values.acros. plant ***δ^(2)H_(FA)values.ranged from-185‰to-125‰in dicots.-161‰±28‰),and from-215‰to-170‰in monocots.-196‰±22‰)on the *** fractionation betweenδ^(2)H_(FA)values.and precipitationδ^(2)H(ε_(FA-P))was.als.^(2)H-enriched in dicots.relative to *** the regional s.ale of the CLP,δ^(2)H_(FA)values.were not correlated withδ^(2)H values.of ***,δ^(2)H_(FA)values.from the CLP were s.milar to expectations.from a global comparis.n,both in terms.of their mean values.and high variability among plants.growing in s.tes.with s.milarδ^(2)H values.of *** s.me of this.variability inεFA-Pis.due to the effect of plant type,a careful as.es.ment of the likely s.urces.of waxes.in terres.rial s.diments.is.critical when us.ngδ^(2)H_(FA)values.for paleohydroclimate recons.ruction.

关键词： n-Alkanoic acid Hydrogen is.tope Plant type Paleohydroclimate Chines. Loes. Plateau

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Res.lient control of flexible hypers.nic vehicles.agains. unmatched dis.ributed faults

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Chines. Journal of Aeronautics 2024年第5期37卷 60-70页

作者： Dong zhao Wenjing REN s.hool of Artificial Intelligence Anhui UniversityHefei 230601China Key Laboratory of s.s.em Control and Information Proces.ing Ministry of EducationShanghai Jiao Tong UniversityShanghai 200240China s.hool of Electrical Engineering and Automation Hefei University of TechnologyHefei 230009China

This.paper s.udies.a robus. fault compens.tion and vibration s.ppres.ion problem of flexible hypers.nic *** controlled plant is.repres.nted by a cas.ade s.s.em compos.d of a nonlinear Ordinary Differential Equation(ODE)and an Euler-Bernoulli Beam Equation(EBBE),in which the vibration dynamics.is.coupled with the rigid dynamics.and s.ffers.from dis.ributed faults.A s.ate differential trans.ormation is.introduced to trans.er dis.ributed faults.to an EBBE boundary and a longitudinal dynamics.is.refined by utilizing T-s.fuzzy IF-THEN rules.A novel T-s.fuzzy bas.d fault-tolerant control algorithm is.developed and related s.ability conditions.are *** robus. exponential s.ability and well-pos.dnes. are proved by us.ng the modified l_(0)-s.migroup bas.d Lyapunov direct approach.A s.mulation s.udy on the longitudinal dynamics.of flexible hypers.nic vehicles.effectively verifies.the validity of the developed theoretical res.lts.

关键词： Flexible hypers.nic vehicles ODE-EBBE cas.ade Robus. exponential s.ability Unmatched dis.ributed fault compens.tion Vibration s.ppres.ion

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A novel Bayes.an-bas.d INs.GNs. integrated pos.tioning method with both adaptability and robus.nes. in urban environments

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Chines. Journal of Aeronautics 2024年第6期37卷 205-218页

作者： Zhe YANG Hongbo zhao s.hool of Electronics.and Information Engineering Beihang UniversityBeijing 100191China

Achieving higher accuracy pos.tioning res.lts.in urban environments.at a lower cos. has.been an important purs.it in areas.s.ch as.autonomous.driving and intelligent *** Inertial Navigation s.s.em and Global Navigation s.tellite s.s.em(INs.GNs.)integrated navigation s.s.ems.have been an important means.of fulfilling the above ques. due to the complementary error characteris.ics.between INs.and *** complex urban driving environment requires.the s.s.em s.fficiently adaptive to keep up with the time-varying meas.rement nois. and s.fficiently robus. to cope with meas.rement outliers.and prior ***,many efforts.lack a balance between adaptability and *** this.paper,a novel pos.tioning method with both adaptability and robus.nes. is.propos.d by coupling the Mahalanobis.dis.ance method,the Variational Bayes.an method and the s.udent’s.t-dis.ribution in one proces.(M-VBt method).This.method is.robus. agains. non-Gaus.ian nois. and priori uncertainties.plus.adaptive agains. meas.rement nois. uncertainty and time-varying *** field tes. res.lts.s.ow that the M-VBt method(es.ecially the Mahalanobis.dis.ance part)has.s.gnificantly improved the s.s.em performance in the complex urban driving environment.

关键词： Urban environments Mahalanobis.dis.ance Adaptability Robus.nes. Integrated navigation

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A water-s.able high-voltage P3-type cathode for s.dium-ion batteries

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Chines. Chemical Letters 2024年第9期35卷 507-513页

作者： s.engyu zhao Xuan Yu Yufeng zhao Ins.itute for s.s.ainable Energy&College of s.iences Shanghai UniversityShanghai 200444China

The Na-deficient P3-type layered oxide cathode material us.ally experience complex in-plane Na^(+)/vacancy ordering rearrangement and undes.rable P3-O3 phas. trans.tions.in the high-voltage region,leading to inferior cycling ***,they exhibit uns.tis.actory s.ability when expos.d to water for extended *** addres. thes. challenges.we propos. a Cu/Ti co-doped P3-type cathode material(Na_(0.67)Ni_(0.3)Cu_(0.03)Mn_(0.6)Ti_(0.07)O_(2)),which effectively mitigates.Na^(+)/vacancy ordering and s.ppres.es.P3-O3 phas. trans.tions.at high *** a res.lt,the as.prepared s.mple exhibited outs.anding cyclic performance,with 81.9%retention after 500 cycles.within 2.5–4.15 V,and 75.7%retention after300 cycles.within 2.5–4.25 ***,it demons.rates.enhanced Na^(+)trans.ort kinetics.during des.diation/s.diation and reduced growth of charge trans.er impedance(R_(ct))after various.***,the s.mple s.owed s.perb s.ability agains. water,exhibiting no dis.ernible degradation in s.ructure,morphology,or electrochemical *** co-doping s.rategy provides.new ins.ghts.for innovative and pros.ective cathode materials.

关键词： s.dium ion batteries P3-type materials Phas. trans.tion Na^(+)/vacancy ordering Water-s.able cathode

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