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Relationship Between Paleogene Reservoir Densification and Hydrocarbon Accumulation in the Xihu Depression

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Journal of Ocean University of China 2021年第4期20卷 777-789页

作者： hu Senqing XU Guosheng zhao Linhai WANG Xu CUI Hengyuan ZHANG Wu MIAO Qing Shanghai Branch of China National Offshore Oil Corporation Shanghai 200050China State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation(Chengdu University of Technology)Chengdu 610059 China

Fluid inclusion analysis and testing were conducted to clarify the relationship between reservoir densification and hydrocarbon accumulation in the Paleogene Pinghu and huagang formations in the Xihu *** hydrocarbon accumulation stages of the reservoirs were studied in combination with the reconstruction results of burial and thermal evolution ***,the relationship between reservoir densification and accumulation charging was clarified in combination with the pore evolutionary *** accordance with the time relation between reservoir densification and hydrocarbon charging,the reservoirs were classified into three types:pre-charging,syn-charging,and after-charging *** indicated that large-scale hydrocarbon charging occurred in 11–*** densification was mainly caused by strong mechanical compaction and pore filling by well-developed siliceous and carbonate *** the middle diagenetic stage A1,the reservoir was under an acidic-diagenetic environment,resulting in the development of secondary dissolution *** large-scale hydrocarbon charging occurred during this period,then an after-charging densification reservoir,which is the most suitable type for hydrocarbon accumulation,might have *** the middle diagenetic stage A2,the reservoir was under an acidic-alkaline transitional diagenetic *** this stage,dissolution became weak,and compaction and cementation were enhanced,resulting in the continuous loss of pore space and reservoir *** the middle diagenetic period B,the reservoir was under an alkaline-diagenetic environment,and the reservoir had been largely *** large-scale hydrocarbon charging occurred during this period,a pre-charging densified reservoir,which is the worst reservoir type for hydrocarbon accumulation,might have developed.

关键词： Xihu Depression accumulation phase hydrocarbon charging reservoir densification diagenetic environment

Transition-metal-catalyzed switchable divergent cycloaddition of para-quinone methides and vinylethylene carbonates:Access to different sized medium-sized heterocycles

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Chinese Chemical Letters 2022年第10期33卷 4549-4558页

作者： Junwei Wang Lei zhao Chen Zhu Ben Ma Xiaolong Xie Jian Liu Shiyun He Magnus Rueping Kun zhao Lihong hu Jiangsu Key Laboratory for Functional Substances of Chinese Medicine School of PharmacyNanjing University of Chinese MedicineNanjing 210023China KAUST Catalysis Center(KCC) King Abdullah University of Science and Technology(KAUST)Thuwal 23955-6900Saudi Arabia Chemistry Key Laboratory of Chemical BiologySchool of PharmacyCheeloo College of MedicineShandong UniversityJi'nan 250012China

Divergent synthesis of medium-sized rings with controllable ring sizes represents a longstanding challenge in organic ***,we developed a transition-metal-catalyzed switchable divergent cycloaddition of para-quinone methides and vinylethylene carbonates by controlling the steric hindrance of *** from reported alkoxide-triggered annulations,this process undergoes a regiodivergent allylation of para-quinone methides followed by 1,6-addition reaction,providing a new route to selectively synthesize seven-to ten-membered nitrogen-containing heterocycles in high yields with excellent *** protocol features a broad substrate scope,wide functional group tolerance as well as operational *** reaction mechanism was investigated by conducting a series of control experiments as well as DFT calculations and the origins of the regioselectivities of the cycloaddition process were rationalized.

关键词： Medium-sized rings Divergent cycloaddition Regioselectivity para-Quinone methides Vinylethylene carbonates

Optimal Culture Capacity of White Shrimp (Litopenaeus vannamei) and Razor Clam (Sinonovacula constricta) in a New Series-Connection Culture Model

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Journal of Ocean University of China 2022年第6期21卷 1641-1648页

作者： hu Jiabao zhao Chunpu BAO Gege LUO Yunhui WANG Danli XU Jilin XU Shanliang School of Marine Sciences Ningbo UniversityNingbo 315211China

To construct an effective circular mix-culture model and investigate its culture capacity,we established one small and one large systems,with white shrimp(Litopenaeus vannamei)and razor clam(Sinonovacula constricta)cultured in separate *** culture water from the *** was pumped to the ***,and the culture water from the *** overflowed back into the *** via *** trial I,we tested four culture densities(groups 1–4),and monitored water quality,growth indices,and digestive and immune enzyme *** the results,the nitrogen and phosphorus levels generally increased then declined after 56 days,and were lower in groups 1 and *** specific growth rate of group 2 was the *** 56 days,activities of four digestive enzymes were increased in group 2,and lysozyme activity was significantly decreased in *** in groups 1–4;Alkaline phosphatase activity of *** was increased in group 3,but decreased in *** in groups 2–4;Acid phosphatase activity was significantly higher in groups 1–3(Phus,we applied group 2 density for trial *** trial II,nitrogen and phosphorus concentrations declined significantly during the latter stages,and growth indices were higher than the control(P<0.05).The yields of *** and *** were significantly higher than the control(P<0.05).The results revealed a good circular mix-culture system with the optimal culture capacity for ***(40 ind m^(−2))and ***(300 ind m^(−2)),which provided a reference for the future culture of them.

关键词： Litopenaeus vannamei Sinonovacula constricta culture capacity series connection culture model water quality

Gold nanorods core/AgPt alloy nanodots shell： A novel potent antibacterial nanostructure

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Nano Research 2013年第11期6卷 822-835页

作者： Xiaona hu Yuyun zhao Zhijian hu Aditya Saran Shuai Hou Tao Wen Wenqi Liu Yinglu Ji Xingyu Jiang Xiaochun Wu CAS Key Laboratory of Standardization and Measurement for Nanotechnology National Center for Nanoscience and Technology Beijing 100190 China CAS Key Laboratory for Biological Effects of Nanamaterials and Nanosafety National Center for Nanoscience and Technology Beijing 100190 China University of Chinese Academy of Sciences Beijing 100049 China

In the light of the current problems of silver nanoparticles （Ag NPs） in terms of antibacterial performance, we have designed a novel trimetallic corelshell nanostructure with AgPt alloy nanodots epitaxially grown on gold nanorods （Au@PtAg NRs） as a potential antibacterial agent. Both Escherichia coli （E. coli） and Staphylococcus aureus （S. aureus） were studied. The antibacterial activity exhibits an obvious composition-dependence. On increasing the Ag fraction in the alloy shell up to 80%, the antibacterial activity gradually increases, demonstrating a flexible way to tune this activity. At 80% Ag, tile antibacterial activity is better than that of a pure Ag shell. The improved antibacterial ability mainly results from the high exposure of silver on the shell surface due to the dot morphology. We thus demonstrate that forming alloys is an effective way to improve antibacterial activity while retaining high chemical stability for Ag-based nanomaterials. Furthermore, due to the tunable localized surface plasmonic response in the near-infrared （NIR） spectral region, additional control over antibacterial activity using light--such as photothermal killing and photo- triggered silver ion release--is expected. As a demonstration, highly enhanced antibacterial activity is shown by utilizing the NIR photothermal effect of the nanostructures. Our results indicate that such tailored nanostructures will find a role in the future fight against bacteria, including the challenge of the increasing severity of multidrug resistance.

关键词： AgPt gold nanorods antibacterial activities composition-dependence photothermal effect

氟比洛芬脂联合侧隐窝阻滞在老年患者下肢骨科手术超前镇痛中的应用

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中国当代医药 2017年第14期24卷 100-102页

作者：曾建峰黄志思刘江梅胡兆云唐超广东省惠州市惠阳区中医院麻醉科广东惠州516211 广东省惠州市惠阳区中医院手术室广东惠州516211 广东省惠州市惠阳区中医院骨伤科广东惠州516211

目的观察氟比洛芬脂联合侧隐窝阻滞在老年患者下肢骨科手术超前镇痛中的应用效果。方法选取2016年1~12月在我院择期行下肢骨科手术的老年患者60例为研究对象,采用随机数字表法分成A、B、C组,每组20例。A组采用氟比洛芬脂+侧隐窝阻滞作... 详细信息

目的观察氟比洛芬脂联合侧隐窝阻滞在老年患者下肢骨科手术超前镇痛中的应用效果。方法选取2016年1~12月在我院择期行下肢骨科手术的老年患者60例为研究对象,采用随机数字表法分成A、B、C组,每组20例。A组采用氟比洛芬脂+侧隐窝阻滞作为联合超前镇痛;B组采用侧隐窝阻滞并术后连续侧隐窝镇痛;C组采用单纯连续硬膜外阻滞。观察三组侧隐窝阻滞和硬膜外阻滞穿刺成功率和穿刺时间,术后VAS疼痛评分及住院天数和住院费用等。结果 A组术后1、4、16、24、48 h的VAS评分均明显低于B、C组,差异有统计学意义(P0.05);A组穿刺成功率为95.0%,明显高于B、C组的85.0%、80.0%,穿刺时间也较B、C组明显缩短,差异均有统计学意义(P<0.05);A组住院时间、住院费用均较B组和C组明显缩短和减少,差异有统计学意义(P<0.05)。结论临床中针对老年患者下肢骨科手术中采用氟比洛芬脂联合侧隐窝阻滞超前镇痛,操作简便,安全有效,穿刺成功率高,并发症少,具有推广意义。

关键词：氟比洛芬脂侧隐窝阻滞下肢骨科手术超前镇痛

All-optical driven soft crawler with complexmotion capabilities

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International Journal of Smart and Nano Materials 2024年第2期15卷 348-364页

作者： Chenchu Zhang Jin Wang Linhan zhao Renfei Chen Qiangqiang zhao Jie zhao Fating Liu Yucheng Bian Heng Zhang Yisen Wang Chaowei Wang Ying hu Anhui Province Key Lab of Aerospace Structural Parts Forming Technology and Equipment Institute of Industry and Equipment TechnologyHefei University of TechnologyHefeiChina CAS Key Laboratory of Mechanical Behavior and Design of Materials Department of Precision Machinery and Precision InstrumentationUniversity of Science and Technology of ChinaHefeiChina GBA Branch of Aerospace Information Research Institute Chinese Academy of SciencesGuangzhouChina

The emergence of millimeter-scale soft actuators has signifi-cantly expanded the potential applications in areas such as search and rescue,drug delivery,and human assistance,due to their high *** these advancements,achieving precise control over the intricate movements of soft crawlers poses a significant *** this study,we have developed an all-optical approach that enables manipulation of propul-sive forces by simultaneously modifying the magnitude and direction of friction forces,thereby enabling complex motions of soft ***,the approach is not constrained by specific actuator shapes,and theoretically,any elongated photothermal actuator can be *** actuator was designed with an isosceles trapezoid shape,featuring a top width of 2mm,a bottom width of 4 mm,and a length of 8 *** our,manipulation approach,we showcase a proof-of-concept for complex soft robotic motions,including crawling(achieving speeds of up to 2.25 body lengths per minute),turning,avoiding obstacles,handling and trans-ferring objects approximately twice its own weight,and navi-gating narrow spaces along programmed *** results showcasethis all-optical manipulationapproach as a promising,yet unexplored tool for the precision and wireless control for the development of advanced soft actuators.

关键词： Light driven soft actuator all-optical manipulation laser manipulation

The role of TGF-β in the tumor microenvironment of pancreatic cancer

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Genes & Diseases 2023年第4期10卷 1513-1524页

作者： Qiang Luo Ziquan hu Hongcheng zhao Yanmei Fan Xiancong Tu Yueqing Wang Xiaowen Liu hubei Key Laboratory of Tumor Microenvironment and Immunotherapy College of Basic Medical ScienceChina Three Gorges UniversityYichangHubei 443003China

Pancreatic cancer(PC)is an aggressive malignant tumor with low rate of surgical resection and poor *** growth factor-β(TGF-β)is a cytokine that has both protumor and antitumor activities,depending on tumor *** interaction be-tween TGF-β signaling and the tumor microenvironment in PC is ***,we reviewed the role of TGF-β in the tumor microenvironment of PC,highlighting producers of TGF-β and TGF-β responders in the tumor microenvironment of PC.

关键词： Cancer therapy Pancreatic cancer Smad 4 Transforming growth factor-β Tumor microenvironment

Specific ion effects on soil aggregate stability and rainfall splash erosion

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International Soil and Water Conservation Research 2022年第4期10卷 557-564页

作者： Jingfang Liu Feinan hu Chenyang Xu Wei Du Zhenghong Yu Shiwei zhao Fenli Zheng State Key Laboratory of Soil Erosion and Dryland Farming on the Loess Plateau College of Natural Resources and EnvironmentNorthwest A&F UniversityYangling712100China Institute of Soil and Water Conservation Chinese Academy of Sciences and Ministry of Water ResourcesYangling712100China College of Agricultural Science and Engineering Hohai UniversityNanjing210098China

Soil interparticle forces can pose important effects on soil aggregate stability and rainfall splash ***,these interparticle forces are strongly influenced by specific ion *** this study,we applied three monovalent cations(Li^(+),Na^(+),and K^(+))with various concentrations to investigate the influence of specific ion effects on aggregate stability and splash erosion via pipette and rainfall simulation *** specific ion effects on soil interparticle forces were quantitatively evaluated by introducing cationic non-classical *** results showed that aggregate stability and splash erosion had strong ion *** breaking strength and splash erosion rate at the same salt concentration followed the sequence as Li^(+)>Na^(+)>K^(+).With decreasing salt concentration,the difference in aggregate breaking strength or splash erosion rate between different cation systems increased initially(1–10^(-2)mol L^(–1))and later was nearly invariable(10^(–2)–10^(–4)mol L^(–1)).The experimental results were well quantitatively explained by soil interparticle forces considering cationic non-classical ***,both aggregate breaking strength and splash erosion rate of three cations revealed a strong positive linear relation with net force subjected to cationic non-classical polarization(R^(2)=0.81,R^(2)=0.81).These results demonstrated that different non-classical polarization of cations resulted in different soil interparticle forces,and thus led to differences in aggregate stability and splash *** study provides valuable information to deeply understand the mechanisms of rainfall splash erosion.

关键词： Aggregate breaking Cationic non-classical polarization Soil interparticle forces Splash erosion Surface potential

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矿石粒度图像在线分析系统的研究与应用

矿山机械 2021年第4期49卷 47-50页

作者：李文博郝兵赵虎马连铭朱成睿张宏星洛阳矿山机械工程设计研究院有限责任公司河南洛阳471039 矿山重型装备国家重点实验室河南洛阳471039 中信重工机械股份有限公司河南洛阳471039

矿石粒度是检验碎磨效果的重要参数。为了实时在线检测矿石粒度,研究了基于机器视觉和工业以太网的矿石粒度图像在线分析系统。结合某钼矿现场,介绍了该系统的设计和应用情况。应用结果表明,矿石粒度图像在线分析系统安装方便,运行稳定... 详细信息

矿石粒度是检验碎磨效果的重要参数。为了实时在线检测矿石粒度,研究了基于机器视觉和工业以太网的矿石粒度图像在线分析系统。结合某钼矿现场,介绍了该系统的设计和应用情况。应用结果表明,矿石粒度图像在线分析系统安装方便,运行稳定,量化了各工段产品性能指标,为碎磨系统智能控制提供了数据支持,可广泛应用于矿山智能化升级改造中。

关键词：矿石粒度图像在线分析系统在线检测机器视觉矿山智能化