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Evaluation of the correlation between ammonia nitrogen and p-toluidine using sequencing batch reactor treating synthetic p-toluidine wastewater

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Journal of Environmental Sciences 2006年第2期18卷 259-262页

作者： zhang Bo chen jin-long WANG Fan zhang Wei-ming zhang Quan-xing Department of Environmental Engineering Nanjing University Nanjing 210093 China

This paper presents lab-scale experiment carried out to evaluate the correlation between ammonia nitrogen （NH3-N） and p-toluidine using sequencing batch reactor treating synthetic p-toluidine wastewater. The profiles of NH3-N and p-toluidine were traced under the concentration of sucrose in the influent varied from 0 to 500 mg/L, aerated airflow varied from 0.6 to 1.2 L/min and temperature varied from 10 to 25℃, respectively. The results showed that the concentration of NH3-N turned from increase to decrease when p-toluidine was nearly completely biodegraded, so the profile of NH3-N could clearly indicate the endpoint of p-toluidine biodegradation. And the profile of NH3-N was not influenced by the sucrose in the influent, aerated airflow and temperature. It is showed that using ammonia nitrogen as monitoring and control parameter is feasible and reliable and has promising application in amine wastewater treatment by SBR.

关键词： sequencing batch reactor correlation ammonia nitrogen p-toluidine biodegradation

Efficient Synthesis of Octalone

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Chemical Research in Chinese Universities 2007年第3期23卷 276-279页

作者： zhang chen chen jin-chun ZHENG Guo-jun LI Yu-lin State Key Laboratory of Applied Organic Chemistry Lanzhou University Lanzhou 730000 P. R. China

A highly efficient and convergent approach for the synthesis of octalone 1, the focal intermediate for the synthesis of several sesquiterpenoids, was developed based on the cationic cyclization strategy of the functio... 详细信息

关键词： Octalone (± )-1β,11-Dihydroxy-△^4-eudesmol Cationic cyclization Sesquiterpenoids Total synthesis

Local recurrence of hepatocellular carcinoma after radiofrequency ablation

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World Journal of Gastroenterology 2010年第40期16卷 5135-5138页

作者： Wang-Jun Liao Min Shi jin-zhang chen Ai-Min Li Department of Oncology Nanfang Hospital Southern Medical University 1838 Guangzhou Avenue North Guangzhou 510515 China

A 51-year-old Chinese male with a 20-year history of hepatitis B was diagnosed with hepatocellular carcinoma in the right anterior portion of the liver, sized 3.5 cm × 3.2 cm, and was treated with radiofrequency ablation (RFA) on December 18, 2001. The patient did not receive antiviral therapy for hepatitis B virus after RFA. The treated lesion reduced gradually and reached its minimum size of 1.7 cm × 1.5 cm seven years later on November 18, 2008. However computed tomography findings revealed that a recurrence lesion of 6.0 cm × 4.8 cm which was histologically confirmed overlapped the previous treated lesion at the 8th year on December 3, 2009. Although recurrence at 8 years after curative RFA is a rare event, such a possibility must be kept in mind. To find and treat the recurrence lesion promptly, long-term and close monitoring is warranted after RFA. Meanwhile, the recurrence-prevention therapy is as important as close monitoring for those patients with a history of hepatitis B.

关键词： Hepatocellular carcinoma Radiofrequency ablation Recurrence

Total laparoscopic liver resection in 78 patients

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World Journal of Gastroenterology 2009年第45期15卷 5727-5731页

作者： Lei zhang Ya-jin chen Chang-Zhen Shang Hong-Wei zhang Ze-Jian Huang Department of Hepatobiliary Surgery Sun Yat-sen Memorial Hospital Sun Yat-sen University Guangzhou 510120 Guangdong Province China

AIM： To summarize the clinical experience of laparoscopic hepatectomy at a single center. METHODS： Between November 2003 and March 2009, 78 patients with hepatocellular carcinoma （n = 39）, metastatic liver carcinoma （n = 10）, and benign liver neoplasms （n = 29） underwent laparoscopic hepatectomy in our unit. A retrospective analysis was done on the clinical outcomes of the 78 patients. RESULTS： The lesions were located in segments Ⅰ （n = 3）, Ⅱ （n = 16）, Ⅲ （n = 24）, Ⅳ （n = 11）, Ⅴ （n = ii）, Ⅵ （n = 9）, and Ⅷ （n = 4）. The lesion sizes ranged from 0.8 to 15 cm. The number of lesions was three （n = 4）, two （n = 8） and one （n = 66） in the study cohort. The surgical procedures included left hemi-hepatectomy （n = 7）, left lateral lobectomy （n = 14）, segmentectomy （n = 11）, local resection （n = 39）, and resection of metastatic liver lesions during laparoscopic surgery for rectal cancer （n = 7）. Laparoscopic liver resection was successful in all patients, with no conversion to open procedures. Only four patients received blood transfusion （400-800 mL）. There were no perioperative complications, such as bleeding and biliary leakage. The liver function of all patients recovered within 1 wk, and no liver failure occurred. CONCLUSION： Laparoscopic hepatectomy is a safe and feasible operation with minimal surgical trauma. It should be performed by a surgeon with sufficient experience in open hepatic resection and who is proficient in laparoscopy.

关键词： Hepatectomy Laparoscopy Liver neoplasms

Optimizing mechanical properties of HIPS fabricated with low-cost desktop 3D printers:investigating the impact of process parameters

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Advances in Manufacturing 2024年第2期12卷 379-395页

作者： jin-Ting Xu Guang-Wei zhang Man-Man chen School of Automotive Engineering Dalian University of TechnologyDalian116024People’s Republic of China

Recently,low-cost desktop three-dimensional(3D)printers,employing the fused deposition modeling(FDM)technique,have gained widespread ***,most users cannot test the strength of printed parts,and little information is available about the mechanical properties of printed high-impact polystyrene(HIPS)parts using desktop 3D *** this study,the user-adjustable parameters of desktop 3D printers,such as crisscross raster orientation,layer thickness,and infill density,were *** experimental plans were designed using the Box-Behnken method,and tensile,3-point bending,and compression tests were carried out to determine the mechanical responses of the printed *** prediction models of the process parameters were regressed to produce the optimal combination of process *** experimental results showcase that the crisscross raster orientation has significant effects on the flexural and compression strengths,but not on the tensile *** an increase in the layer thickness,the tensile,flexural,and compression strengths first decreased and then increased,reaching their minimum values at approximately 0.16 mm layer *** addition,they all increased with an increase of infill *** was demonstrated that when the raster orientation,layer thickness,and infill density were 13.08°/–76.92°,0.09 mm,and 80%,respectively,the comprehensive mechanical properties of the printed HIPS were *** results can help end-users of desktop 3D printers understand the effects of process parameters on the mechanical properties,and offer practical suggestions for setting proper printing parameters for fabricating HIPS parts.

关键词： Desktop three-dimensional(3D)printers Fused deposition modeling(FDM) High-impact polystyrene(HIPS) Process parameters

An adaptive physics-informed deep learning method for pore pressure prediction using seismic data

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Petroleum Science 2024年第2期21卷 885-902页

作者： Xin zhang Yun-Hu Lu Yan jin Mian chen Bo Zhou State Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum(Beijing)Beijing102249China College of Petroleum Engineering China University of Petroleum(Beijing)Beijing102249China College of Artificial Intelligence China University of Petroleum(Beijing)Beijing102249China PetroChina Tarim Oilfield Company KorlaXinjiang841000China

Accurate prediction of formation pore pressure is essential to predict fluid flow and manage hydrocarbon production in petroleum *** deep learning technique has been receiving more interest due to the great potential to deal with pore pressure ***,most of the traditional deep learning models are less efficient to address generalization *** fill this technical gap,in this work,we developed a new adaptive physics-informed deep learning model with high generalization capability to predict pore pressure values directly from seismic ***,the new model,named CGP-NN,consists of a novel parametric features extraction approach(1DCPP),a stacked multilayer gated recurrent model(multilayer GRU),and an adaptive physics-informed loss *** machine training,the developed model can automatically select the optimal physical model to constrain the results for each pore pressure *** CGP-NN model has the best generalization when the physicsrelated metricλ=0.5.A hybrid approach combining Eaton and Bowers methods is also proposed to build machine-learnable labels for solving the problem of few *** validate the developed model and methodology,a case study on a complex reservoir in Tarim Basin was further performed to demonstrate the high accuracy on the pore pressure prediction of new wells along with the strong generalization *** adaptive physics-informed deep learning approach presented here has potential application in the prediction of pore pressures coupled with multiple genesis mechanisms using seismic data.

关键词： Pore pressure prediction Seismic data 1D convolution pyramid pooling Adaptive physics-informed loss function High generalization capability

Elastic Properties of Particulate Composites with Imperfect Interface

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Journal of Wuhan University of Technology(Materials Science) 2002年第2期17卷 78-82页

作者：陈军明 Wuhan University of Technology ***

An effective analytical approach is developed for the problem of pardculate composites containing spherical inclusion with imperfect interface between the matrix and spherical inclusions. In this paper, a general interface model for a variety of interfaced defects has been presented, in which both displacement discontinuity across the interface and the elastic moduli varing with radius outside of the inclusion are considered, The imperfect interface conditions are appropriate in the case of thin coatings on the inclusion. Furthermore, in the case of thin elastic interphase, the displacement field and the stress field in the inclusion and matrix are exactly solved for the boundary problem of hydrostatic compression of an infinite spherical symmetrical body by Frobenius series , and the expression of the normal interface parameter, Dr, is derived. In addition, it has been proved that two previous results derived in some literatures by considering the interface to be a thin interphase with displacement jump or with some variance in its moduli can be reverted from the present formula, respectively. Numerical results are given to demonstrate the significance of the general imperfect interface effects.

关键词： spherical inclusion imperfect interface particulate composite displacement field stress field

Type 1 regulatory T cells： a new mechanism of periphera immune tolerance

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Cellular & Molecular Immunology 2015年第5期12卷 566-571页

作者： Hanyu Zeng Rong zhang Boquan jin Lihua chen Department of Immunology The Fourth Military Medical University Xi'an 710032 Shaanxi China

The lack of immune response to an antigen, a process known as immune tolerance, is essential for the preservation of immune homeostasis. To date, two mechanisms that drive immune tolerance have been described extensively： central tolerance and peripheral tolerance. Under the new nomenclature, thymus-derived regulatory T （tTreg） ceils are the major mediators of central immune tolerance, whereas peripherally derived regulatory T （PTreg） cells function to regulate peripheral immune tolerance. A third type of Treg ceils, termed iTreg, represents only the in vitro-induced Treg cellsz. Depending on whether the cells stably express Foxp3, pTreg, and iTreg cells may be divided into two subsets： the classical CD4＋Foxp3＋ Treg cells and the CD4＋Foxp3- type 1 regulatory T （Trl） cells2. This review focuses on the discovery, associated biomarkers, regulatory functions, methods of induction, association with disease, and clinical trials of Trl cells.

关键词： biomarkers clinical trials regulatory functions type 1 regulatory T cells

Lift-Off Effect of Koch and Circular Differential Pickup Eddy Current Probes

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Chinese Journal of Mechanical Engineering 2024年第2期37卷 283-293页

作者： Guolong chen Zheng Cao Shuaishuai zhang Ji Wei Wei Gao Wuyin jin School of Mechanical and Electrical Engineering Lanzhou University of TechnologyLanzhou 730050China

A flexible or planar eddy current probe with a differential structure can suppress the lift-off noise during the inspection of ***,the extent of the lift-off effect on differential probes,including different coil structures,*** this study,two planar eddy current probes with differential pickup structures and the same size,Koch and circular probes,were used to compare lift-off *** eddy current distributions of the probes perturbed by 0°and 90°cracks were obtained by finite element *** analysis results show that the 90°crack can impede the eddy current induced by the Koch probe even further at relatively low lift-off *** peak-to-peak values of the signal output from the two probes were compared at different lift-off distances using finite element analysis and experimental *** addition,the effects of different frequencies on the lift-off were studied *** results show that the signal peak-to-peak value of the Koch probe for the inspection of cracks in 90°orientation is larger than that of the circular probe when the lift-off distance is smaller than 1.2 *** addition,the influence of the lift-off distance on the peak-to-peak signal value of the two probes was studied via *** indicates that the influence becomes more evident with an increase in excitation *** research discloses the lift-off effect of differential planar eddy current probes with different coil shapes and proves the detection merit of the Koch probe for 90°cracks at low lift-off distances.

关键词： Eddy current testing Differential pickup probe Fractal Koch curve Flexible eddy current probe