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Low crude protein formulation with supplemental amino acids for its impacts on intestinal health and growth performance of growing-finishing pigs

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Journal of Animal Science and Biotechnology 2024年第4期15卷 1590-1606页

作者： Marcos Elias Duarte Wanpuech Parnsen shihai zhang Marvio L.T.Abreu Sung Woo Kim Department of Animal Science North Carolina State UniversityRaleighNC 27695USA

Background Low crude protein(CP)formulations with supplemental amino acids(AA)are used to enhance intestinal health,reduce costs,minimize environmental impact,and maintain growth performance of ***,extensive reduction of dietary CP can compromise growth performance due to limited synthesis of non-essential AA and limited availability of bioactive compounds from protein supplements even when AA requirements are ***,implementing a low CP formulation can increase the net energy(NE)content in feeds causing excessive fat *** supplementation of functional AA,coupled with low CP formulation could further enhance intestinal health and glucose metabolism,improving nitrogen utilization,and growth *** experiments were conducted to evaluate the effects of low CP formulations with supplemental AA on the intestinal health and growth performance of growing-finishing *** In Exp.1,90 pigs(19.7±1.1 kg,45 barrows and 45 gilts)were assigned to 3 treatments:CON(18.0%CP,supplementing Lys,Met,and Thr),LCP(16.0%CP,supplementing Lys,Met,Thr,Trp,and Val),and LCPT(16.1%CP,LCP+0.05%SID Trp).In Exp.2,72 pigs(34.2±4.2 kg BW)were assigned to 3 treatments:CON(17.7%CP,meeting the requirements of Lys,Met,Thr,and Trp);LCP(15.0%CP,meeting Lys,Thr,Trp,Met,Val,Ile,and Phe);and VLCP(12.8%CP,meeting Lys,Thr,Trp,Met,Val,Ile,Phe,His,and Leu).In Exp.3,72 pigs(54.1±5.9 kg BW)were assigned to 3 treatments and fed experimental diets for 3 phases(grower 2,finishing 1,and finishing 2).Treatments were CON(18.0%,13.8%,12.7%CP for 3 phases;meeting Lys,Met,Thr,and Trp);LCP(13.5%,11.4%,10.4%CP for 3 phases;meeting Lys,Thr,Trp,Met,Val,Ile,and Phe);and LCPG(14.1%,12.8%,11.1%CP for 3 phases;LCP+Glu to match SID Glu with CON).All diets had 2.6 Mcal/kg *** In Exp.1,overall,the growth performance did not differ among *** LCPT increased(P<0.05)Claudin-1 expression in the duodenum and *** LCP and LCPT increased(P<0.05)CAT-1,4F2hc,and B0AT exp

关键词： Amino acids Growing-finishing pigs Growth performance Intestinal health Low crude protein formulation Net energy

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Plant essential oils combined with organic acids restored lipopolysaccharide-induced leaky intestine via gut microbial modulation in weaned piglets

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Animal Nutrition 2024年第3期18卷 419-432页

作者： Xiaoyu Zheng Yibo Wang Xuemei Zhou Tanyi Deng Yueqi Zhao Zhichao Fu Yulong Wei Wen Ma shihai zhang Wutai Guan Fang Chen State Key Laboratory of Swine and Poultry Breeding Industry College of Animal ScienceSouth China Agricultural UniversityGuangzhou 510642China Guangdong Laboratory for Lingnan Modern Agriculture South China Agricultural UniversityGuangzhou 510642China College of Animal Science and National Engineering Research Center for Breeding Swine Industry South China Agricultural UniversityGuangzhou 510642China

Intestine derived lipopolysaccharide(LPS)is closely related to systemic inflammation and disorders,yet little is known about its roles in the weanling stress of piglets and its potential as a nutritional intervention *** study aimed to investigate the potential of essential oils(EO)and organic acids(OA)in mitigating weaning stress in piglets by modulating the circulation of intestine derived ***-two weaned piglets at 21 d old with body weight of 8.12±0.168 kg were randomly divided into a control group(CON)and an experimental group,each consisting of six pens with six piglets per pen,and were fed either a basal diet or a basal diet supplemented with 3 kg/t OA+500 g/t EO(EO+OA).On the 14th day of the feeding trial,12 weaned piglets were randomly selected from the CON group,and 6 piglets were selected from the experimental *** on diet composition and stress treatment,these 18 piglets were divided into the following three groups:1)CON *** were fed a basal diet and received an intraperitoneal injection of saline as a control.2)LPS *** were fed a basal diet and received an intraperitoneal injection of LPS(100μg/kg body weight)to induce stress.3)EO+OA+LPS *** were fed a basal diet supplemented with EO and OA and received an intraperitoneal injection of LPS(100μg/kg body weight)to induce *** results showed that EO+OA significantly ameliorated the oxidative imbalance and inflammation disorder induced by LPS in piglets'serum and intestine by inhibiting the activation of the Toll-like receptor 4(TLR4)/nuclear factor-kappa B(NF-κB)/mitogen-activated protein kinase(MAPK)signaling ***,compared to the LPS group,supplementation with EO+OA restored LPS-induced reductions in Bcl-2 protein expression in the piglets'intestines(P<0.05)and mitigated morphological damage;it also enhanced both the protein expression and relative gene expression of the tight junction proteins occludin and claudin-1(P<0.05),and redu

关键词： Weaned piglet Essential oil Organic acid Gut microbiota Lipopolysaccharide

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Dietary supplementation of benzoic acid and essential oils combination enhances intestinal resilience against LPS stimulation in weaned piglets

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Journal of Animal Science and Biotechnology 2024年第2期15卷 878-897页

作者： Chang Cui Yulong Wei Yibo Wang Wen Ma Xiaoyu Zheng Jun Wang Ziwei Ma Caichi Wu Licui Chu shihai zhang Wutai Guan Fang Chen Guangdong Provincial Key Laboratory of Animal Nutrition Control College of Animal ScienceSouth China Agricultural UniversityGuangzhou 510642China College of Animal Science and National Engineering Research Center for Breeding Swine Industry South China Agricultural UniversityGuangzhou 510642China Guangdong Laboratory for Lingnan Modern Agriculture South China Agricultural UniversityGuangzhou 510642China

Background The benefits of combining benzoic acid and essential oils(BAO)to mitigate intestinal impairment during the weaning process have been well established,while the detailed underlying mechanism has not been fully *** research has primarily focused on the reparative effects of BAO on intestinal injury,while neglecting its potential in enhancing intestinal stress *** In this study,we investigated the pre-protective effect of BAO against LPS-induced stress using a modified experimental *** were pre-supplemented with BAO for 14 d,followed by a challenge with LPS or saline to collect blood and intestinal *** Our findings demonstrated that BAO supplementation led to significant improvements in piglets’final weight,average daily gain,and feed intake/body gain ***,BAO supplementation positively influenced the composition of intestinal microbiota,increasing beneficial Actinobacteriota and Alloprevotella while reducing harmful Desulfobacterota,Prevotella and ***,BAO supplementation effectively mitigated oxidative disturbances and inflammatory responses induced by acute LPS *** was evidenced by elevated levels of T-AOC,SOD,and GSH,as well as decreased levels of MDA,TNF-α,and IL-6 in the ***,piglets subjected to LPS challenge and pre-supplemented with BAO exhibited significant improvements in intestinal morphological structure and enhanced integrity,as indicated by restored expression levels of Occludin and Claudin-1 compared to the non-supplemented *** analysis revealed that BAO supplementation enhanced the jejunal antioxidative capacity by increasing GSH-Px levels and decreasing MDA levels under the LPS challenge and stimulated the activation of the Nrf2 signaling ***,the reduction of TLR4/NF-κB/MAPK signaling pathways activation and proinflammatory factor were also observed in the jejunal of those piglets fed with ***

关键词： Anti-stress Benzoic acid Essential oils Intestine LPS Weaned piglets

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中华优秀传统文化同科学社会主义价值观主张高度契合的道德观阐释

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当代世界社会主义问题 2024年第1期 19-25,164,165页

作者：张士海山东大学马克思主义学院济南250100

党的二十大报告关于中华优秀传统文化同科学社会主义价值观主张具有高度契合性的重要论断,不仅提取和凝练了中华优秀传统文化的特质禀赋和核心价值理念,还指明了马克思主义基本原理与中华优秀传统文化在中国语境中相契合的事实支点。其... 详细信息

党的二十大报告关于中华优秀传统文化同科学社会主义价值观主张具有高度契合性的重要论断,不仅提取和凝练了中华优秀传统文化的特质禀赋和核心价值理念,还指明了马克思主义基本原理与中华优秀传统文化在中国语境中相契合的事实支点。其中,道德作为衡量个体人格品质、调整社会生活方式、维系人与人之间社会关系的规范系统,是科学社会主义理论的一个重要范畴,而中华民族几千年的文明发展史建立了一套相对完整的伦理道德体系。

关键词：中华优秀传统文化社会主义价值观社会生活方式核心价值理念人格品质伦理道德体系中国语境道德观

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薄盘工件加工过程中的不平衡量分析及去重方法研究

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现代制造工程 2024年第4期 123-128页

作者：万国良张仕海屈重年张宗艺天津职业技术师范大学机械工程学院天津300222

薄盘工件是转子机构上常见的零/部件,在装配调试前通常需要进行动平衡测试与校正。目前常用的不平衡校正方法存在加工与校正分离、平衡工艺复杂,以及效率低等问题。基于该问题提出在薄盘工件加工过程中不平衡量校正的方法,结合复合数控... 详细信息

薄盘工件是转子机构上常见的零/部件,在装配调试前通常需要进行动平衡测试与校正。目前常用的不平衡校正方法存在加工与校正分离、平衡工艺复杂,以及效率低等问题。基于该问题提出在薄盘工件加工过程中不平衡量校正的方法,结合复合数控机床的主轴准停、刀具定位及去重控制等功能,进行薄盘工件不平衡量在线去重校正。同时,为了提高薄盘工件不平衡量在线去重校正精度,提出一种附加去重率的迭代控制方法,并从理论上证明了该方法的稳定性。通过仿真计算讨论了附加去重率的迭代控制方法优势,探讨了理想去重率的选取问题。研究内容可以在无动平衡机的情况下实现薄盘工件不平衡量在线去重校正,对创新性解决薄片工件平衡成本高、效率低等问题以及提高工件加工精度等方面具有重要的意义。

关键词：薄盘工件不平衡量去重建模迭代去重去重率

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多重透视电子游戏:北京大学师生的具身体验与行业观察——北京大学新闻与传播学院李典峰等访谈实录

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数字出版研究 2024年第3期3卷 8-18页

作者：李典峰张世海北京大学新闻与传播学院北京100091 黄淮学院文化传媒学院驻马店463000

电子游戏已经成为中国数以亿计人口的日常娱乐载体,也是当代青少年流行文化和社交渠道的重要组成部分。但在特定游戏玩家群体中,也存在家庭与社会问题诱发的游戏沉迷或成瘾现象。职业电竞是电子游戏发展的专业化竞技形态,已形成一套完... 详细信息

电子游戏已经成为中国数以亿计人口的日常娱乐载体,也是当代青少年流行文化和社交渠道的重要组成部分。但在特定游戏玩家群体中,也存在家庭与社会问题诱发的游戏沉迷或成瘾现象。职业电竞是电子游戏发展的专业化竞技形态,已形成一套完整的培训模式、俱乐部体系和产业链。中国原创游戏吸收了中华优秀传统文化元素,运用世界流行的游戏视听语言,走出一条独特的发展道路,成为世界游戏市场的一支重要力量。游戏技术由于玩家反馈快、迭代周期短、商业利润高,成为人工智能技术发展的强劲动力,孕育出大量高科技公司。《数字出版研究》专访北京大学新闻与传播学院博雅博士后、讲师李典峰,尝试以微知著,观察并探讨中国高校师生对于电子游戏的体验和认知,以及游戏技术和产业的衍生逻辑。

关键词：电子游戏具身体验游戏沉迷游戏技术

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BP-PSO-based intelligent case retrieval method for high-rise structural form selection

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Science China(Technological Sciences) 2013年第4期56卷 940-944页

作者： zhang shihai OU JinPing School of Civil Engineering Nanyang Institute of Technology Faculty of Infrastructure Engineering Dalian University of Technology

Modern architectures are developing in the direction of tall buildings and complex structures,and the theoretical analysis and the design experience have seriously lagged behind the construction of super high-rise *** form selection,especially the case based reasoning (CBR) based structural form selection,is a promising tool for the construction of high-rise *** view of the limit of cognitive ability of domain experts,a BP (back propagation)-PSO (particle swarm optimization)-based intelligence case retrieval method for high-rise structural form selection is *** CBR-based case retrieval method and the construction of the BP-PSO neutral network are *** then the BP-PSO-based case retrieval method is validated by some engineering *** results of training and prediction indicate that the proposed method has good ability to retrieve the cases of high-rise structures.

关键词： structural form selection case based reasoning high-rise structure BP-PSO neutral network

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基于改进YOLOX-s算法的航天太阳电池缺陷检测

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太阳能学报 2024年第9期45卷 276-284页

作者：李振伟张仕海屈重年汝承印陈康静天津职业技术师范大学机械工程学院天津300222

针对航天太阳电池表面缺陷检测问题,提出基于机器视觉与深度学习的缺陷检测方法。通过航天太阳电池缺陷检测系统获取图像,并依据企业电池片缺陷的分类标准构建航天太阳电池缺陷数据集。采用切片技术获取包含缺陷目标的子图像数据集,解... 详细信息

针对航天太阳电池表面缺陷检测问题,提出基于机器视觉与深度学习的缺陷检测方法。通过航天太阳电池缺陷检测系统获取图像,并依据企业电池片缺陷的分类标准构建航天太阳电池缺陷数据集。采用切片技术获取包含缺陷目标的子图像数据集,解决卷积和下采样操作信息丢失而导致召回率低的问题。针对不同缺陷采取适当的图像增强方式进行扩充数据集,以避免训练过程中因数据集不足导致的过拟合问题。采用深度可分离卷积、优化损失函数、双线性插值上采样及引入注意力机制等方法对YOLOX-s算法进行改进,以获得综合效果最佳的航天太阳电池缺陷检测模型。通过不同数据集训练及检测精度指标对比,以及消融实验验证改进模型的有效性。通过改进模型与同类主流模型对比实验,验证改进模型在航天太阳电池缺陷检测方面的优越性。

关键词：太阳电池机器视觉深度学习 YOLOX-s 缺陷检测

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泥水盾构带压更换刀筒闸门技术研究

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北方建筑 2024年第1期9卷 48-51页

作者：张捷张世海张晨曦林赉贶中交天和机械设备制造有限公司江苏常熟215500 中南大学机电工程学院湖南长沙410006

泥水盾构施工过程中常压换刀刀盘因频繁换刀会引起刀筒闸门磨损,更换刀筒闸门时,刀筒闸门周围土体需处于相对稳定状态,否则会引起塌方或涌水等问题,甚至可能导致盾构机淹没等安全事故。以南京市和燕路过江通道为工程背景,研究并解决了... 详细信息

泥水盾构施工过程中常压换刀刀盘因频繁换刀会引起刀筒闸门磨损,更换刀筒闸门时,刀筒闸门周围土体需处于相对稳定状态,否则会引起塌方或涌水等问题,甚至可能导致盾构机淹没等安全事故。以南京市和燕路过江通道为工程背景,研究并解决了带压更换刀筒闸门的施工重难点,包括地下水的封堵、泥膜形成、舱内气压稳定等,提出了包括制作止水环、形成泥膜、带压更换刀筒闸门等环节的施工操作规程,最终取得了良好的施工效果。

关键词：泥水盾构刀筒闸门带压换刀

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Nutritional strategies to alleviate oxidative stress in sows

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Animal Nutrition 2022年第2期9卷 60-73页

作者： Qihui Li Siwang Yang Fang Chen Wutai Guan shihai zhang Guangdong Province Key Laboratory of Animal Nutrition Control College of Animal ScienceSouth China Agricultural UniversityGuangzhou 510642China College of Animal Science and National Engineering Research Center for Breeding Swine Industry South China Agricultural UniversityGuangzhou 510642China Guangdong Laboratory for Lingnan Modern Agriculture South China Agricultural UniversityGuangzhou 510642China

The performance of high-yielding sows is directly related to the productivity of pig farming. Fetaldevelopment mainly occurs during the last month of pregnancy, and the aggressive metabolic burden ofsows during this stage eventually leads to systemic oxidative stress. When affected by oxidative stress,sows exhibit adverse symptoms such as reduced feed intake, hindered fetal development, and evenabortion. In addition, milk synthesis during the lactation period causes a severe metabolic burden. Thebiological response to oxidative stress during this period is associated with a decrease in milk production,which further affects the growth of piglets. Understanding the nutritional strategies to alleviateoxidative stress in sows is crucial to maintain their reproduction and lactation performance. Recently,advances have been made in the field of nutrition to relieve oxidative stress in sows during late pregnancyand lactation. This review highlights the nutritional strategies to relieve oxidative stress in sowsreported within the last 20 years.

关键词： Sow Oxidative stress Nutritional strategy Plant extract Selenium Vitamin E

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