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Advanced preparation and application of bimetallic materials in lithium-sulfur batteries:A review

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Journal of Energy Chemistry 2024年第1期88卷 469-512,I0011页

作者： Yongbing Jin Nanping Deng Yanan Li Hao Wang meiling zhang Weimin Kang Bowen Cheng State Key Laboratory of Separation Membranes and Membrane Processes/National Center for International Joint Research on Separation Membranes School of Textile Science and EngineeringTiangong UniversityTianjin 300387China

Lithium-sulfur(Li-S)batteries are considered highly promising as next-generation energy storage systems due to high theoretical capacity(2600 Wh kg^(-1))and energy density(1675 mA h g^(-1))as well as the abundant natural reserves,low cost of elemental sulfur,and environmentally friendly ***,several challenges impede its commercialization including low conductivity of sulfur itself,the severe“shuttle effect”caused by lithium polysulfides(LiPSs)during charge–discharge processes,volume expansion effects and sluggish reaction *** a solution,polar metal particles and their compounds have been introduced as the main hosts for sulfur cathode due to their robust catalytic activity and adsorption capability,effectively suppressing the“shuttle effect”of Li *** alloys and their compounds with multi-functional properties exhibit remarkable electrochemical performance more readily when compared to single-metal ***-designed bimetallic materials demonstrate larger specific surface areas and richer active sites,enabling simultaneous high adsorption capability and strong catalytic *** synergistic effect of the“adsorption-catalysis”sites accelerates the adsorptiondiffusion-conversion process of Li PSs,ultimately achieving a long-lasting Li-S ***,the latest progress and performance of bimetallic materials in cathodes,separators,and interlayers of Li-S batteries are systematically ***,the principles and challenges of Li-S batteries are briefly ***,various mechanisms for suppressing“shuttle effects”of Li PSs are emphasized at the ***,the performance parameters of various bimetallic materials are comprehensively summarized,and some improvement strategies are proposed based on these ***,the future prospects of bimetallic materials are discussed,with the hope of providing profound insights for the rational design and manufacturing of high-performance bimetallic materia

关键词： Bimetallic materials Lithium-sulfur batteries Effectively suppress shuttle effect of LiPSs Significantly improve reaction kinetics Exceptionally long lifespan

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Probiotic Pediococcus pentosaceus restored gossypol-induced intestinal barrier injury by increasing propionate content in Nile tilapia

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Journal of Animal Science and Biotechnology 2024年第4期15卷 1688-1703页

作者： Feifei Ding Nannan Zhou Yuan Luo Tong Wang Weijie Li Fang Qiao Zhenyu Du meiling zhang Laboratory of Aquaculture Nutrition and Environmental Health(LANEH) School of Life SciencesEast China Normal UniversityShanghai 200241China

Background Intestinal barrier is a dynamic interface between the body and the ingested food components, however, dietary components or xenobiotics could compromise intestinal integrity, causing health risks to the host. Gossypol, a toxic component in cottonseed meal(CSM), caused intestinal injury in fish or other monogastric animals. It has been demonstrated that probiotics administration benefits the intestinal barrier integrity, but the efficacy of probiotics in maintaining intestinal health when the host is exposed to gossypol remains unclear. Here, a strain(YC) affiliated to Pediococcus pentosaceus was isolated from the gut of Nile tilapia(Oreochromis niloticus) and its potential to repair gossypol-induced intestinal damage was *** A total of 270 Nile tilapia(2.20 ± 0.02 g) were allotted in 3 groups with 3 tanks each and fed with 3 diets including CON(control diet), GOS(control diet containing 300 mg/kg gossypol) and GP(control diet containing 300 mg/kg gossypol and 10^(8) colony-forming unit(CFU)/g P. pentosaceus YC), respectively. After 10 weeks, addition of P. pentosaceus YC restored growth retardation and intestinal injury induced by gossypol in Nile tilapia. Transcriptome analysis and si RNA interference experiments demonstrated that NOD-like receptors(NLR) family caspase recruitment domain(CARD) domain containing 3(Nlrc3) inhibition might promote intestinal stem cell(ISC) proliferation, as well as maintaining gut barrier integrity. 16S r RNA sequencing and gas chromatography-mass spectrometry(GC-MS) revealed that addition of P. pentosaceus YC altered the composition of gut microbiota and increased the content of propionate in fish gut. In vitro studies on propionate's function demonstrated that it suppressed nlrc3 expression and promoted wound healing in Caco-2 cell *** The present study reveals that P. pentosaceus YC has the capacity to ameliorate intestinal barrier injury by modulating gut microbiota composition and elevating

关键词： Gut barrier injury Gossypol ISCs proliferation Nlrc3 Propionate

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Paeoniflorin ameliorates chronic colitis via the DR3 signaling pathway in group 3 innate lymphoid cells

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Journal of Pharmaceutical Analysis 2024年第6期14卷 889-901页

作者： Shaowei Huang Xueqian Xie Bo Xu Zengfeng Pan Junjie Liang meiling zhang Simin Pan Xiaojing Wang Meng Zhao Qing Wang Jinyan Chen Yanyang Li Lian Zhou Xia Luo School of Pharmaceutical Sciences Guangzhou University of Chinese Medicine510006China School of Basic Medicine Guangzhou University of Chinese Medicine510006China First Clinical Medical College Guangzhou University of Chinese Medicine510000China

Inhibiting the death receptor 3(DR3)signaling pathway in group 3 innate lymphoid cells(ILC3s)presents a promising approach for promoting mucosal repair in individuals with ulcerative colitis(UC).Paeoniflorin,a prominent component of Paeonia lactiflora Pall.,has demonstrated the ability to restore barrier function in UC mice,but the precise mechanism remains *** this study,we aimed to delve into whether paeoniflorin may promote intestinal mucosal repair in chronic colitis by inhibiting DR3 signaling in ILC3s.C57BL/6 mice were subjected to random allocation into 7 distinct groups,namely the control group,the 2%dextran sodium sulfate(DSS)group,the paeoniflorin groups(25,50,and 100 mg/kg),the anti-tumor necrosis factor-like ligand 1A(anti-TL1A)antibody group,and the IgG *** detected the expression of DR3 signaling pathway proteins and the proportion of ILC3s in the mouse colon using Western blot and flow cytometry,***,DR3-overexpressing MNK-3 cells and 2%DSS-induced Rag1^(-/-)mice were used for *** results showed that paeoniflorin alleviated DSS-induced chronic colitis and repaired the intestinal mucosal ***,paeoniflorin inhibited the DR3 signaling pathway in ILC3s and regulated the content of cytokines(interleukin-17A,granulocyte-macrophage colony stimulating factor,and interleukin-22).Alternatively,paeoniflorin directly inhibited the DR3 signaling pathway in ILC3s to repair mucosal damage independently of the adaptive immune *** additionally confirmed that paeoniflorin-conditioned medium(CM)restored the expression of tight junctions in Caco-2 cells via *** conclusion,paeoniflorin ameliorates chronic colitis by enhancing the intestinal barrier in an ILC3-dependent manner,and its mechanism is associated with the inhibition of the DR3 signaling pathway.

关键词： Paeoniflorin Ulcerative colitis Intestinal mucosal barrier DR3 signaling pathway Group 3 innate lymphoid cells

Evaluating short-term and long-term liver fibrosis improvement in hepatitis C patients post-DAA treatment

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Journal of biomedical research 2024年第5期38卷 1-10页

作者： Yifan Wang Xinyan Ma Yanzheng Zou Ming Yue meiling zhang Rongbin Yu Hongbo Chen Peng Huang Department of Infectious Disease Jurong Hospital Affiliated to Jiangsu University Jurong Jiangsu China. Department of Epidemiology Center for Global Health School of Public Health Nanjing Medical University Nanjing Jiangsu 211166 China. Department of Infectious Diseases the First Affiliated Hospital of Nanjing Medical University Nanjing Jiangsu 210029 China.

Despite achieving a high cure rate with direct-acting antivirals (DAAs) in hepatitis C treatment, further research is needed to identify additional benefits of the DAA therapy. The current study evaluated liver fibrosis improvement in 848 hepatitis C patients treated with DAAs, who also achieved sustained virologic response (SVR). Using the fibrosis-4 (FIB-4) index, patients were categorized based on their baseline fibrosis level, and improvements in fibrosis were analyzed in both the short-term (9-26 weeks) and long-term (≥ 36 weeks) follow-up. The results showed a significant decrease in the FIB-4 index, indicating an improvement in liver fibrosis, in 63.00% of the patients during the short-term follow-up and 67.56% during the long-term follow-up. Short-term improvement was associated with factors including ribavirin (RBV) usage, blood cholinesterase levels, alanine transaminase levels, albumin levels, and the baseline FIB-4 index. Additionally, long-term improvement was associated with factors such as aspartate transaminase levels, total protein level, and the baseline FIB-4 index. The current study emphasizes the importance of continuous assessment and post-treatment monitoring of liver fibrosis, providing crucial insights for enhancing patient care in hepatitis C management.

关键词： chronic hepatitis C direct-acting antivirals liver fibrosis sustained virologic response

Evaluating short-term and long-term liver fibrosis improvement in hepatitis C patients after DAA treatment

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The Journal of Biomedical Research 2024年第05期 464-472页

作者： Yifan Wang Xinyan Ma Yanzheng Zou Ming Yue meiling zhang Rongbin Yu Hongbo Chen Peng Huang Department of Infectious Disease Jurong Hospital Affiliated to Jiangsu University Department of Epidemiology Center for Global Health School of Public Health Nanjing Medical University Department of Infectious Diseases the First Affiliated Hospital of Nanjing Medical University

Despite achieving a high cure rate with the direct-acting antivirals(DAAs) in hepatitis C treatment, further research is needed to identify additional benefits of the DAA therapy. The current study evaluated liver fibrosis improvement in 848 hepatitis C patients treated with DAAs, who also achieved sustained virologic response. By the fibrosis-4(FIB-4) index, patients were categorized based on their baseline fibrosis levels, and the improvement in fibrosis was analyzed in both short-term(9–26 weeks) and long-term(≥ 36 weeks) *** results showed a significant decrease in the FIB-4 index, indicating an improvement in liver fibrosis, in63.0% and 67.6% of the patients during the short-term and long-term follow-up, respectively. Short-term improvement was associated with factors including ribavirin usage, blood cholinesterase levels, alanine transaminase levels, albumin levels, and the baseline FIB-4 index, while long-term improvement was associated with factors such as aspartate transaminase levels, total protein level, and the baseline FIB-4 index. The current study emphasizes the importance of continuous assessment and post-treatment monitoring of liver fibrosis, which will provide crucial insights for enhancing patient care in hepatitis C management.

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陆兴祺治藏相关问题考述

中国边疆史地研究 2024年第2期34卷 100-112,223页

作者：张媚玲张亚栋云南师范大学历史与行政学院 650500

陆兴祺治藏是中国近代西藏治理史的重要部分。民国初年,陆兴祺以中间路线获北洋政府认可,得任要职,但情报工作却频现失误,并夸大了其在阻签“西姆拉条约”中的作用。北洋之后,陆兴祺改换门庭陷入派系斗争,未曾入藏的经历及其商人身份被... 详细信息

陆兴祺治藏是中国近代西藏治理史的重要部分。民国初年,陆兴祺以中间路线获北洋政府认可,得任要职,但情报工作却频现失误,并夸大了其在阻签“西姆拉条约”中的作用。北洋之后,陆兴祺改换门庭陷入派系斗争,未曾入藏的经历及其商人身份被病并放大,最终被南京政府边缘化。纵观陆兴祺治藏生涯,守成有余,进取不足。

关键词：陆兴祺西藏治理西姆拉会议藏事会议

基于DAYCENT模型的甘南高寒草甸土壤有机碳含量动态模拟及影响因素的灰色关联度分析

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环境科学学报 2024年第6期44卷 384-394页

作者：田景张美玲王晨张锐祺李钊甘肃农业大学理学院数量生物学研究中心兰州730070

全球土壤有机碳中的10%~30%是草地土壤有机碳,其在调节生态系统平衡方面发挥着重要的作用.本研究以甘南州高寒草甸为研究对象,通过野外实测数据和文献中的参数范围对DAYCENT模型进行参数校准,使其适用于甘南州高寒草甸土壤有机碳含量的... 详细信息

全球土壤有机碳中的10%~30%是草地土壤有机碳,其在调节生态系统平衡方面发挥着重要的作用.本研究以甘南州高寒草甸为研究对象,通过野外实测数据和文献中的参数范围对DAYCENT模型进行参数校准,使其适用于甘南州高寒草甸土壤有机碳含量的模拟.利用灰色关联度量化海拔、气温和降水与土壤有机碳含量之间的关系.结果表明:1993—2023年土壤总有机碳含量呈下降趋势,与缓性、惰性土壤有机碳含量的变化一致.土壤总有机碳含量在土壤有机碳库中变化幅度是最大的,减少了0.1 g·kg^(-1).活性土壤有机碳含量由于占比较少,其变化幅度最小,减少了0.05 g·kg^(-1).空间上表现为由西南向东北逐渐减少,且有机碳的含量随着土层的增加而减少.土壤有机碳含量的变化与海拔和降水量的变动具有一致性,而与温度呈反向一致性.灰色关联度分析结果表明,降水对土壤有机碳含量的影响最大.

关键词： DAYCENT模型土壤有机碳含量高寒草甸灰色关联度分析甘南

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益生菌对幼鱼生长发育的影响及调控机制

水产学报 2024年第1期48卷 19-27页

作者：张美玲董温昕杜震宇华东师范大学生命科学学院

近年来，高密度、集约化的水产养殖模式导致养殖鱼类疾病频发，其中幼鱼发病率和死亡率的上升严重影响水产养殖业的健康快速发展。如何保障幼鱼的健康是当前水产养殖业亟需解决的问题。益生菌能够通过多种方式提高幼鱼的抗病力、增强幼... 详细信息

近年来，高密度、集约化的水产养殖模式导致养殖鱼类疾病频发，其中幼鱼发病率和死亡率的上升严重影响水产养殖业的健康快速发展。如何保障幼鱼的健康是当前水产养殖业亟需解决的问题。益生菌能够通过多种方式提高幼鱼的抗病力、增强幼鱼对营养素的摄取、促进幼鱼的生长发育。已有大量的研究阐述了益生菌在幼鱼生长发育及免疫调节中的作用，但相关机制还需深入探究。本文综述了近年来益生菌在幼鱼生长发育及抗病方面发挥的有益作用及其可能的机制，讨论了益生菌在幼鱼养殖应用时可能存在的问题以及发展方向，为益生菌在水产动物幼体养殖中的应用提供了理论参考。

关键词：幼鱼益生菌水产养殖发育肠道菌群

未来气候情景下青藏高原草地净初级生产力时空演变特征

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水土保持研究 2024年第2期31卷 190-201页

作者：徐士博张美玲宿茂鑫甘肃农业大学理学院兰州730070

[目的]揭示SSP126和SSP585两种气候情景下,不同气候因素(气温和降水)对青藏高原草地净初级生产力的影响,阐明青藏高原地区影响草地净初级生产力时空分布特征的主控气候因素,为未来青藏高原地区植被生态系统的综合治理提供理论依据。[方... 详细信息

[目的]揭示SSP126和SSP585两种气候情景下,不同气候因素(气温和降水)对青藏高原草地净初级生产力的影响,阐明青藏高原地区影响草地净初级生产力时空分布特征的主控气候因素,为未来青藏高原地区植被生态系统的综合治理提供理论依据。[方法]基于青藏高原48个气象站点基准期(1971—2020年)的日值气象数据、土壤类型数据以及模型所需要的站点管理数据,利用DAILY CENTURY(DAYCENT)模型,结合文献中对应站点的NPP实测值和MOD17A3遥感数据,对模型参数进行了校准,利用均方根误差、可决系数、效率系数等统计指标对模型模拟结果进行了评价。其次单向嵌套BCC-CSM1.1气候模式,对未来气候SSP126和SSP585情景下的青藏高原草地净初级生产力进行预测,并对预测结果进行了时空统计分析。[结果](1)在SSP126和SSP585情景下青藏高原草地NPP均呈现出由东南向西北递减的分布特征,且NPP值较高的区域主要位于青藏高原的东南部,NPP值较低的区域则位于青藏高原以西的区域;(2)在SSP126情景下,青藏高原草地净初级生产力总体呈现出下降趋势,波动范围最大的是长远期(2081—2100年),减小幅度为12.1%;在SSP585情景下,NPP总体呈现出平稳的上升趋势,其中近期(2021—2040年)的增长速率最高为12%;(3)与基准期(1971—2021年)相比,在SSP126和SSP585情景下,青藏高原85%以上的草地NPP呈现下降趋势,其中SSP126和SSP585与基准期(1971—2020)相比NPP值分别相对减少28%,23%。[结论]两种不同气候情景下,温度与NPP的相关性均高于降水。低温少雨是造成青藏高原西北地区草地NPP减少的主要原因。

关键词： DAYCENT模型未来气候情景净初级生产力青藏高原

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