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Effect of Soil Sampling Density on Detected Spatial Variability of Soil Organic Carbon in a Red Soil Region of china

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Pedosphere 2011年第2期21卷 207-213页

作者： YU Dong-Sheng zhang Zhong-Qi YANG Hao SHI Xue-{1. TAN Man-Zhi SUN {2.-Xia WANG Hong-Jie College of geographical {1. Nanjing Normal University Nanjing 210046 (China) State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil Science Chinese Academy of Sciences Nanjing 210008(China) Graduate University of chinese Academy of {1. Beijing 100099 (China) Xuzhou Normal Unsiversity Xuzhou 221116 (China)

Spatial variability of soil organic carbon (SOC) of different land use patterns and soil types was examined in a county-wide red soil region of South china,using six sampling densities,1.,34,68,1.0,{1.5,and 5{1. samples designed by the method of grid sampling in 6 different grid sizes,labeled as D1.,D34,D68,D1.0,D{1.5,and D5{1.,*** results showed that the coefficients of variation (CVs) of SOC decreased gradually from 6{1.8% to 47.4% with the increase in soil sampling *** SOC CVs in the paddy field change slightly from 30.8% to {1..7%,while those of the dry farmland and forest land decreased remarkably from 58.1. to 48.7% and from 99.3% to 64.4%,*** SOC CVs of the paddy soil change slightly,while those of red soil decreased remarkably from 8{1.8% to 63.9%.About 604,500,and 353 (P 1.5{1.g kg-1.based on the CVs of SOC acquired from the present sampling densities of D1.,D68,and D5{1.,***,based on the same SOC change and the present time CVs at D{1.5,the ratio of samples needed for paddy field,dry farmland,and forest land should be 1.0.81.3.33,while the actual corresponding ratio in an equal interval grid sampling was 1.0.74:*** indicated that the sampling density had important effect on the detection of SOC variability in the county-wide region,the equal interval grid sampling was not efficient enough,and the respective CV of each land use or soil type should be fully considered when determining the sampling number in the future.

关键词： coefficient of variation county-wide region grid sampling land use soil type

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Photoluminescence Investigation of Charge Build-Up Process in the Emitter of a Double-Barrier Resonant Tunneling Structure

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chinese Physics Letters 1996年第9期13卷 707-710页

作者： LUO Ke-jian zheng Hou-zhi {1. Ting LI Cheng-fang YANG Xiao-ping {1. Peng-hua {1. wei TIAN Jin-fa National Laboratory for Superlattices and Microstructures Institute of SemiconductorsChinese Academy of SciencesBeijing 100083

Charge build-up process in the emitter of a double-barrier resonant tunneling structure is studied by using photoluminescence *** evidence is obtained that the charge accumulation in the emitter keeps almost constant with bias voltages in the resonant regime,while it increases remarkably with bias voltages beyond resonant *** optical results are in good agreement with the electrical *** is demonstrated that the band gap renormalization plays a certain role in the experiment.

关键词： measurement emitter resonant

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Assessment of CMIP6 model performance for temperature and precipitation in Xinjiang,china

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Atmospheric and Oceanic Science Letters 2022年第2期15卷 39-46页

作者： Xiaolu zhang Lijuan {1. Dabang Jiang College of Earth and Planetary sciences University of Chinese Academy of SciencesBeijingChina institute of Atmospheric Physics Chinese Academy of SciencesBeijingChina

In this study,the authors evaluate the skill of 42.climate models from phase 6 of the Coupled Model Intercomparison Project(CMIP6)in reproducing the climatological temperature and precipitation in Xinjiang during the period 1.95–*** results indicate that the models can reliably capture the {1. distributions of the two *** regionally averaged bias of temperature is 0.1. for the annual mean,-1.6℃ in spring,0.5℃ in summer,-0.2. in autumn,and 1.3℃ in *** averaged annual and seasonal precipitation in Xinjiang is generally overestimated by the CMIP6 *** simulated annual precipitation is 89%more than the observation over Xinjiang,with a regionally averaged bias of 2.6%in spring,-3%in summer,84%in autumn,and 2.8%in *** analysis indicates that most models overestimate the spatial variability of both climatological temperature and *** models show smaller discrepancies in simulating the temperature than the precipitation in *** comparison,both the median and arithmetic mean of the 42.models have similar skills to those of 2. selected good models,and outperform most individual models.

关键词： CMIP6 Evaluation Temperature Precipitation Xinjiang

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An immunomodulatory polypeptide hydrogel for osteochondral defect repair

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Bioactive Materials 2023年第1期19卷 678-689页

作者： Meng Yang zheng-Chu {1. Fu-Zhen Yuan Rong-Hui Deng Xin Yan Feng-Biao Mao You-Rong Chen {2. Lu Jia-Kuo Yu Department of Sports Medicine Beijing Key Laboratory of Sports InjuriesPeking University Third HospitalBeijing100191China beijing National Laboratory for Molecular {1. Center for Soft Matter Science and EngineeringKey Laboratory of Polymer Chemistry and Physics of Ministry of EducationCollege of Chemistry and Molecular EngineeringPeking UniversityBeijing100871People’s Republic of China institute of Sports Medicine of Peking University Beijing100191China institute of Medicine Innovation and {1. Peking University Third Hospital Beijing100191China

Osteochondral injury is a common and frequent orthopedic disease that can lead to more serious degenerative joint *** engineering is a promising modality for osteochondral repair,but the implanted scaffolds are often immunogenic and can induce unwanted foreign body reaction(FBR).Here,we prepare a polypept(o)ide-based PAA-RGD hydrogel using a novel thiol/thioester dual-functionalized hyperbranched polypeptide P(EG3Glu-co-Cys)and maleimide-functionalized polysarcosine under biologically benign *** PAA-RGD hydrogel shows suitable biodegradability,excellent biocompatibility,and low immunogenicity,which together lead to optimal performance for osteochondral repair in New Zealand white rabbits even at the early stage of *** in vitro and in vivo mechanistic studies corroborate the immunomodulatory role of the PAA-RGD hydrogel,which induces minimum FBR responses and a high level of polarization of macrophages into the immunosuppressive M2.*** findings demonstrate the promising potential of the PAA-RGD hydrogel for osteochondral regeneration and highlight the importance of *** results may inspire the development of PAA-based materials for not only osteochondral defect repair but also various other tissue engineering and bio-implantation applications.

关键词： Osteochondral regeneration Polypeptide hydrogel Immunoregulation Foreign-body reaction Mesenchymal stem cells

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GCH1.plays a role in the high-altitude adaptation of Tibetans

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Zoological research 2017年第3期38卷 155-162页

作者： Yong-Bo Guo Yao-Xi He Chao-Ying Cui Ouzhuluobu Baimakangzhuo Duojizhuoma Dejiquzong Bianba Yi Peng Cai-juan Bai Gonggalanzi Yong-Yue Pan Qula Kangmin Cirenyangji Baimayangji wei Guo Yangla Hui {1. Xiao-Ming {1. Wang-Shan zheng Shu-hua Xu hua Chen Sheng-Guo Zhao Yuan Cai Shi-Ming Liu Tian-Yi Wu Xue-Bin Qi Bing Su College of Animal Science and Technology Gansu Agricultural University Lanzhou Gansu 730070 China State Key Laboratory of Genetic resources and Evolution Kunming Institute of Zoology Chinese Academy of Sciences Kunming Yunnan 650223 China High Altitude Medical research Center School of Medicine Tibetan University Lhasa Tibet 850000 China Kunming College of Life Science University of Chinese Academy of Sciences Kunming Yunnan 650204 China chinese Academy of {1. Key Laboratory of Computational Biology Max Planck Independent Research Group on Population Genomics CAS-MPG Partner Institute for Computational Biology (PICB) Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai 200031 China Center for Computational Genomics Beijing Institute of Genomics Chinese Academy of Sciences Beijing 100101 China National Key Laboratory of High Altitude Medicine High Altitude Medical Research Institute Xining Qinghai 810012 China School of Life Science and Technology Shanghai Tech University Shanghai 200031 China Collaborative Innovation Center of Genetics and Development Shanghai 200438 China

Tibetans are welt adapted to high-altitude hypoxia. Previous genome-wide scans have reported many candidate genes for this adaptation, but only a few have been studied. Here we report on a hypoxia gene （GCH1. GTP-cyclohydrolase I）, involved in maintaining nitric oxide synthetase （NOS） function and normal blood pressure, that harbors many potentially adaptive variants in Tibetans. We resequenced an 80.8 kb fragment covering the entire gene region of GCH1.in 50 unrelated Tibetans Combined with previously published data, we demonstrated many GCHI variants showing deep divergence between highlander Tibetans and lowlander Han chinese. Neutrality tests confirmed a signal of positive Darwinian selection on GCH1.in Tibetans. Moreover, association analysis indicated that the Tibetan version of GCH1.was significantly associated with multiple physiological traits in Tibetans, including blood nitric oxide concentration, blood oxygen saturation and hemoglobin concentration. Taken together, we propose that GCH1.plays a role in the genetic adaptation of Tibetans to high altitude hypoxia.

关键词： GCH1 Positive selection TibetanHypoxia adaptation Nitric oxide HemoglobinOxygen saturation

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EP300 contributes to high-altitude adaptation in Tibetans by regulating nitric oxide production

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Zoological research 2017年第3期38卷 163-170页

作者： Wang-Shan zheng Yao-Xi He Chao-Ying Cui Ouzhuluobu Dejiquzong Yi Peng Cai-Juan Bai Duojizhuoma Gonggalanzi Bianba Baimakangzhuo Yong-Yue Pan Qula Kangmin Cirenyangji Baimayangji {1. GUO Yangla Hui {2. Xiao-Ming {2. Yong-Bo Guo Shu-hua Xu hua Chen Sheng-Guo Zhao Yuan Cai Shi-Ming Liu Tian-Yi Wu Xue-Bin Qi Bing Su College of Animal Science and Technology Gansu Agricultural University Lanzhou Gansu 730070 China State Key Laboratory of Genetic resources and Evolution Kunming Institute of Zoology Chinese Academy of Sciences Kunming Yunnan 650223 China High Altitude Medical research Center School of Medicine Tibetan University Lhasa Tibet 850000 China Kunming College of Life Science University of Chinese Academy of Sciences Kunming Yunnan 650204 China chinese Academy of {1. Key Laboratory of Computational Biology Max Planck Independent Research Group on Population Genomics CAS-MPG Partner Institute for Computational Biology Shanghai Institutes for Biological Sciences Chinese Academy ofSciences Shanghai 200031 China Center for Computational Genomics Beijing Institute of Genomics Chinese Academy of Sciences Beijing 100101 China National Key Laboratory of High Altitude Medicine High Altitude Medical Research Institute Xining Qinghai 810012 China School of Life Science and Technology Shanghai Tech University Shanghai 200031 China Collaborative Innovation Center of Genetics and Development Shanghai 200438 China

The genetic adaptation of Tibetans to high altitude hypoxia likely involves a group of genes in the hypoxic pathway, as suggested by earlier studies. To test the adaptive role of the previously reported candidate gene EP300 （histone acetyltransferase p300）, we conducted resequencing of a 1.8.9 kb gene region of EP300 in 80 unrelated Tibetans. The allele-frequency and haplotype-based neutrality tests detected signals of positive Darwinian selection on EP300 in Tibetans, with a group of variants showing allelic divergence between Tibetans and lowland reference populations, including Han chinese, Europeans, and Africans. Functional prediction suggested the involvement of multiple EP300 variants in gene expression regulation. More importantly, genetic association tests in {1.6 Tibetans indicated significant correlation of the adaptive EP300 variants with blood nitric oxide （NO） concentration. Collectively, we propose that EP300 harbors adaptive variants in Tibetans, which might contribute to high-altitude adaptation through regulating NO production.

关键词： Tibetans High altitude Hypoxia EP300 Genetic adaptation Nitric oxide

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Database system for managing 2.,0002.-inch PMTs at JUNO

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Nuclear Science and Techniques 2022年第3期33卷 10-21页

作者： Jun Wang Nikolay Anfimov Jing-Yuan Guo Yu Gu Hang Hu Min Li Qiu-Mei Ma Alexander Olshevskiy Zhao-Yuan Peng Zhong-hua Qin Alexander Tietzsch Bjorn Wonsak {1. Wang Zhi-Min Wang Mei-Hang Xu Wan Xie {2.-Yun You Hai-Qiong zhang Rong Zhao School of Physics Sun Yat-Sen UniversityGuangzhou 510275China Joint institute for Nuclear {1. Dubna 141980Russia College of Science and Engineering Ji Nan UniversityGuangzhou 510632China institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China University of chinese Academy of {1. Beijing 100049China State Key Laboratory of Particle Detection and Electronics Beijing 100049China Physikalisches Institut Eberhard Karls Universitat Tubingen72074 TubingenGermany Institut fur Experimentalphysik Universitat Hamburg20148 HamburgGermany Sino-French institute of Nuclear Engineering and Technology Sun Yat-Sen UniversityZhuhai 519082China

A database system,known as the large PMT characterization and instrumentation database system(LPMT-CIDS),was designed and implemented for the Jiangmen Underground Neutrino Observatory(JUNO).The system is based on a Linux+Apache+MySQL+PHP(LAMP)server and focuses on modularization and architecture *** covers all the testing stages for the 2.-inch photomultiplier tubes(PMTs)at JUNO and provides its users with data storage,analysis,and visualization *** on the successful use of the system in the 2.-inch PMT testing program,its design approach and construction elements can be extended to other projects.

关键词： LAMP Photomultiplier tubes Jiangmen underground neutrino observatory Data visualization

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Decrease of plasma N-terminal pro p-type natriuretic peptide as a predictor of clinical improvement after cardiac resynchronization therapy for heart failure

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chinese Medical Journal 2009年第6期122卷 617-621页

作者： DING Li-gang hua {1. {2. Shu CHU Jian-min CHEN Ke-ping WANG Yang WANG Fang-zheng CHEN Xin Centre of Arrhythmia Diagnosis and Treatment Cardiovascular institute and Fu Wai Hospital Chinese Academy and Medical Sciences & Peking Union Medical College Beijing 100037 China Division of Biometrics Cardiovascular Institute and Fu Wai Hospital Chinese Academy and Medical Sciences & Peking Union Medical College Beijing 100037 China

Background N-terminal pro β-type natriuretic peptide （NT pro BNP） has been shown to predict the prognosis and could guide the treatment of heart failure. We aimed to investigate the values of NT pro BNP in predicting the clinical response to cardiac resynchronization therapy （CRT）. Methods A total of 44 patients with chronic heart failure （34 male and 1. female, mean age of （58±1.） years, New York Heart Association （NYHA） class 3.3±0.5, QRS duration （1.0±1.） milliseconds） who underwent successful implantation of a CRT system were enrolled in this study. Pharmacotherapy remained stable during the first 3 months of follow-up. Plasma levels of NT pro BNP were evaluated before and 3 months after implantation. Clinical, echocardiographic and exercise parameters were monitored at each clinical visit after CRT implantation. Receiver operating characteristic analysis and a paired ttest were performed to analyze the data. Results After a mean of （1..3±5.5） months of follow-up, 1. nonresponders were identified. CRT resulted in a significant reduction in NT pro BNP （（1.70±1.2.） vs （1.07±0.88） pmol/ml, P 〈0.001. in responders. Percentage change in NT pro BNP level （△BNP%） was a statistically significant predictor of long term clinical improvement at 3 months of follow-up. Conclusions △BNP% from baseline to 3 months of follow-up is a predictor of long term response to CRT. NT pro BNP may be a simple method for monitoring the effects of CRT.

关键词： N-terminal pro β type natriuretic peptide chronic heart failure cardiac resynchronization therapy

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Bioassay-guided isolation of saikosaponins with agonistic activity on 5-hydroxytryptamine 2. receptor from Bupleurum chinense and their potential use for the treatment of obesity

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chinese Journal of {1. Medicines 2017年第6期15卷 467-473页

作者： SUN Chang-Li GENG Chang-An huaNG Xiao-Yan MA Yun-Bao {1. Xiao-Hong YANG Tong-hua CHEN Xing-Long YIN Xiu-Juan zhang Xue-Mei CHEN Ji-Jun State Key Laboratory of Phytochemistry and Plant resources in West{1. Kunming Institute of Botany Chinese Academy of Sciences Kunming 650201 China University of chinese Academy of {1. Beijing 100049 China

5-Hydroxytryptamine 2.(5-HT2.) receptor is one of the major targets of anti-obesity agents, due to its role in regulation of appetite. In the present study, the 70% EtO H extract of the roots of Bupleurum chinense was revealed to have agonistic activity on 5-HT2.C receptor, and the subsequent bioassay-guided isolation led to identification of several saikosaponins as the active constituents with 5-HT2.C receptor agonistic activity in vitro and anti-obesity activity in vivo. The new compound, 2.-oxosaikosaponin d(1), was determined by extensive spectroscopic analyses(HR-ESI-MS, IR, and 1D and 2. NMR). The primary structure-activity relationship study suggested that the intramolecular ether bond between C-13 and C-2. and the number of sugars at C-3 position were closely related to the 5-HT2.C receptor agonistic activity. Saikosaponin a(3), the main saponin in B. chinense, showed obviously agonistic activity on 5-HT2.C receptor with an EC50 value of 2..08 ± 0.33 μmol×L^(–1) in vitro and could reduce food intake by 39.1% and 69.2., and weight gain by 13.6% and 16.4%, respectively, at 3.0 and 6.0 mg×kg^(–1) in vivo. This investigation provided valuable information for the potential use of B. chinense as anti-obesity agent.

关键词： Bupleurum chinense 5-hydroxytryptamine 2.(5-HT2.) receptor Anti-obesity Saikosaponins

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Lateralβ-Ga_(2.O_(3)Schottky barrier diode fabricated on(-2.1.single crystal substrate and its temperature-dependent current-voltage characteristics

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chinese Physics B 2022年第4期31卷 634-637页

作者： Pei-Pei Ma Jun zheng Ya-Bao {1. Xiang-Quan Liu Zhi Liu Yu-{2. Zuo Chun-Lai Xue Bu-Wen Cheng State Key Laboratory on Integrated Optoelectronics Institute of SemiconductorsChinese Academy of SciencesBeijing 100083China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China

Lateralβ-Ga_(2.O_(3)Schottky barrier diodes(SBDs)each are fabricated on an unintentionally doped(-2.1.n-typeβ-Ga_(2.O_(3)single crystal substrate by designing L-shaped *** introducing sidewall electrodes on both sides of the conductive channel,the SBD demonstrates a high current density of 2.3 mA/mm and low specific on-resistance of4.7 mΩ·cm^(2..Temperature-dependent performance is studied and the Schottky barrier height is extracted to be in a range between 1.3 eV and 1.35 eV at temperatures ranging from 2.℃to 1.0℃.These results suggest that the lateralβ-Ga_(2.O_(3)SBD has a tremendous potential for future power electronic applications.

关键词： β-Ga_(2.O_(3) Schottky barrier diodes rectifying ability breakdown voltage

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