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Towards an Artificial Intelligence Framework for Data-Driven Prediction of Coronavirus Clinical Severity

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Computers, Materials & Continua 2020年第4期63卷 537-551页

作者： Xiangao Jiang Megan Coffee Anasse Bari Junzhang Wang Xinyue Jiang Jianping Huang Jichan Shi Jianyi Dai Jing Cai Tianxiao zhang Zhengxing Wu guiqing He Yitong Huang Department of Infectious Diseases Wenzhou Central HospitalWenzhou325000China Division of Infectious Diseases and Immunology Department of MedicineNew York UniversityNew YorkUSA Department of Population and Family Health Mailman School of Public HealthColumbia UniversityNew YorkUSA Courant Institute of Mathematical Sciences Computer Science DepartmentNew York UniversityNew YorkUSA Columbia College Columbia UniversityNew YorkUSA Departments of Infectious Diseases Cangnan People’s HospitalWenzhou325800China Department of Gynaecology Wenzhou Central HospitalWenzhou325000China

The virus SARS-CoV2,which causes the Coronavirus disease COVID-19 has become a pandemic and has spread to every inhabited *** the increasing caseload,there is an urgent need to augment clinical skills in order to identify from among the many mild cases the few that will progress to critical *** present a first step towards building an artificial intelligence(AI)framework,with predictive analytics(PA)capabilities applied to real patient data,to provide rapid clinical decision-making ***-19 has presented a pressing need as a)clinicians are still developing clinical acumen given the disease’s novelty,and b)resource limitations in a rapidly expanding pandemic require difficult decisions relating to resource *** objectives of this research are:(1)to algorithmically identify the combinations of clinical characteristics of COVID-19 that predict outcomes,and(2)to develop a tool with AI capabilities that will predict patients at risk for more severe illness on initial *** predictive models learn from historical data to help predict specifically who will develop acute respiratory distress syndrome(ARDS),a severe outcome in *** experimental results based on two hospitals in Wenzhou,Zhejang,China identify features most predictive of ARDS in COVID-19 initial presentation which would not have stood out to clinicians.A mild increase in elevated alanine aminotransferase(ALT)(a liver enzyme)),a presence of myalgias(body aches),and an increase in hemoglobin,in this order,are the clinical features,on presentation,that are the most *** two centers’COVID-19 case series symptoms on initial presentation can help predict severe *** models that learned from historical data of patients from two Chinese hospitals achieved 70%to 80%accuracy in predicting severe cases.

关键词： SARS-CoV2 COVID-19 coronavirus infectious diseases artificial intelligence predictive analytics

低频穴位电刺激联合六步法乳房按摩对剖宫产产妇母乳喂养、泌乳功能和产后心理状态的影响

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四川中医 2024年第8期42卷 213-216页

作者：罗义华张贵清袁代莉李芳芳邓尚莉程新慧王宇赵厶维达州市中西医结合医院妇产科四川达州635000

目的:探讨低频穴位电刺激联合六步法乳房按摩对剖宫产产妇母乳喂养、泌乳功能和产后心理状态的影响。方法:选取2022年9月~2022年12月在我院产科剖宫产分娩的120名产妇为研究对象。随机分为观察组和对照组,各60例。对照组予以六步法乳房... 详细信息

目的:探讨低频穴位电刺激联合六步法乳房按摩对剖宫产产妇母乳喂养、泌乳功能和产后心理状态的影响。方法:选取2022年9月~2022年12月在我院产科剖宫产分娩的120名产妇为研究对象。随机分为观察组和对照组,各60例。对照组予以六步法乳房按摩,观察组予以低频穴位电刺激联合六步法乳房按摩。采用母乳喂养测量工具(breast-feeding assessment tool,BAT)、母乳喂养自我效能量表(breastfeeding self-efficacy scale,BSES)及产后42d纯母乳喂养率评估母乳喂养情况;记录产妇泌乳始动时间、泌乳量、产后48h乳房胀痛程度及产后24、48、72h血清泌乳素(prolactin,PRL)水平;于产后72h、42d采用爱丁堡产后抑郁量表(edinburgh postnatal depression scale,EPDS)评估产妇产后心理状态。结果:观察组BAT评分、首次母乳喂养成功率、产后42d纯母乳喂养率以及产后72h、42d BSES评分均高于对照组(P24、48、72h PRL水平均高于对照组(P2h、42d EPDS评分均低于对照组(P<0.05)。结论:低频穴位电刺激联合六步法乳房按摩可提高剖宫产产妇母乳喂养率和母乳喂养自信心,改善乳房胀痛,促进泌乳功能和产后心理健康,是一种值得推广的产后乳房护理方法。

关键词：低频穴位电刺激六步法乳房按摩剖宫产产妇母乳喂养泌乳功能心理状态

Reactive changes in astrocytes, and delayed neuronal death, in the rat hippocampal CA1 region following cerebral ischemia/reperfusion

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Neural Regeneration Research 2009年第1期4卷 36-41页

作者： guiqing zhang Xiang Luo Zhiyuan Yu Chao Ma Shabei Xu Wei Wang Department of Neurology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 Hubei Province China Department of Rehabilitation and Psychology First Affiliated Hospital Medical College Xinjiang Shihezi University Shihezi 832008 Xinjiang Uygur Autonomous Region China Normal College Xinjiang Shihezi University Shihezi 832000 Xinjiang Uygur Autonomous Region China

BACKGROUND： Blood supply to the hippocampus is not provided by the middle cerebral artery. However, previous studies have shown that delayed neuronal death in the hippocampus may occur following focal cerebral ischemia induced by middle cerebral artery occlusion. OBJECTIVE： To observe the relationship between reactive changes in hippocampal astrocytes and delayed neuronal death in the hippocampal CA1 region following middle cerebral artery occlusion. DESIGN, TIME AND SETTING： The immunohistochemical, randomized, controlled animal study was performed at the Laboratory of Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, from July to November 2007. MATERIALS： Rabbit anti-glial fibrillary acidic protein （GFAP）（Neomarkers, USA）, goat anti-rabbit IgG （Sigma, USA） and ApoAlert apoptosis detection kit （Biosciences Clontech, USA） were used in this study. METHODS： A total of 42 healthy adult male Wistar rats, aged 3–5 months, were randomly divided into a sham operation group （n = 6） and a cerebral ischemia/reperfusion group （n = 36）. In the cerebral ischemia/reperfusion group, cerebral ischemia/reperfusion models were created by middle cerebral artery occlusion. In the sham operation group, the thread was only inserted into the initial region of the internal carotid artery, and middle cerebral artery occlusion was not induced. Rats in the cerebral ischemia/reperfusion group were assigned to a delayed neuronal death （＋） subgroup and a delayed neuronal death （–） subgroup, according to the occurrence of delayed neuronal death in the ischemic side of the hippocampal CA1 region following cerebral ischemia. MAIN OUTCOME MEASURES： Delayed neuronal death in the hippocampal CA1 region was measured by Nissl staining. GFAP expression and delayed neuronal death changes were measured in the rat hippocampal CA1 region at the ischemic hemisphere by double staining for GFAP and TUNEL. RESULTS： After 3 days of ischemia

关键词： cerebral ischemia hippocampus delayed neuronal death astrocytes glial fibrillaryacidic protein

Acoustic vector sensor signal processing

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Chinese Journal of Acoustics 2006年第1期25卷 1-15页

作者： SUN guiqing LI Qihu zhang Bin Institute of Acoustics The Chinese Academy of Sciences Beijing 100080

Acoustic vector sensor simultaneously, colocately and directly measures orthogonal components of particle velocity as well as pressure at single point in acoustic field so that is possible to improve performance of traditional underwater acoustic measurement devices or detection systems and extends new ideas for solving practical underwater acoustic engineering problems. Although acoustic vector sensor history of appearing in underwater acoustic area is no long, but with huge and potential military demands, acoustic vector sensor has strong development trend in last decade, it is evolving into a one of important underwater acoustic technology. Under this background, we try to review recent progress in study on acoustic vector sensor signal processing, such as signal detection, DOA estimation, beamforming, and so on.

关键词： acoustic measurement acoustic engineering signal processing particle velocity development trend signal detection acoustic field

减少农田土壤氮损失的微生物调控技术研究进展

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山东科学 2024年第2期37卷 117-126页

作者：许冬宁吴晓青周方园范素素张新建肖桂青王加宁湖南农业大学生物科学技术学院湖南长沙410128 齐鲁工业大学(山东省科学院)山东省科学院生态研究所山东省应用微生物重点实验室山东济南250103

氮肥为现代农业生产提供了作物生长需求的氮素,但长期不合理施用氮肥造成资源浪费、经济损失和影响深远的环境问题。微生物在氮素循环中发挥重要作用,值得研究总结。基于已有研究成果,归纳土壤氮素循环中的固氮、硝化、反硝化、氨化和同... 详细信息

氮肥为现代农业生产提供了作物生长需求的氮素,但长期不合理施用氮肥造成资源浪费、经济损失和影响深远的环境问题。微生物在氮素循环中发挥重要作用,值得研究总结。基于已有研究成果,归纳土壤氮素循环中的固氮、硝化、反硝化、氨化和同化/异化作用等重要微生物驱动过程及机制;归纳了微生物技术调控农业氮损失旨在提升农业环境可持续性的策略包括增加氮固定、减少温室气体排放、控制氮素流失和氨挥发等。这些策略展示了微生物在减少氮肥依赖和提高作物产量中的应用潜力,同时也指出了实现田间有效应用的研究局限和技术挑战。

关键词：农田土壤氮素循环氮素损失微生物调控氮肥减施增效

电感耦合等离子体原子发射光谱法测定尾气净化用金属载体催化剂中的铂、钯和铑含量

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中国资源综合利用 2024年第2期42卷 10-16页

作者：王才平陈能郁丰善黄庆刘贵清何治鸿王翀张保明杨帆张金良刘成鹏横峰县凯怡实业有限公司江西省君鑫贵金属科技材料有限公司江西上饶335500 江苏北矿金属循环利用科技有限公司江苏徐州221121

如何精准地测定汽车尾气催化剂的贵金属含量(铂、钯、铑),对于控制贵金属的成本、回收贵金属及控制催化剂的性能具有重要意义。试验采用电感耦合等离子体原子发射光谱法来测定尾气用净化金属载体催化剂中的铂(Pt)、钯(Pd)和铑(Rh)含量... 详细信息

如何精准地测定汽车尾气催化剂的贵金属含量(铂、钯、铑),对于控制贵金属的成本、回收贵金属及控制催化剂的性能具有重要意义。试验采用电感耦合等离子体原子发射光谱法来测定尾气用净化金属载体催化剂中的铂(Pt)、钯(Pd)和铑(Rh)含量。具有而言,含有尾气净化用金属载体催化剂的试样采用盐酸进行预处理,然后加入聚环氧乙烷溶液降低胶粒对过滤的影响,过滤产物在马弗炉(300℃)内进行炭化处理,并加入20 g Na_(2)O_(2),经过沉淀凝聚实现富集分离。最后,采用电感耦合等离子体原子发射光谱仪对分离的铂、钯、铑的含量进行测定。在样品测定过程中,Pt、Pd和Rh的加标回收率分布范围表现良好,分别为97.1%~109.0%、91.0%~101.8%和93.2%~102.2%。该方法具有快速定量分析、检出限较低、精密度良好、动态范围宽的特点,为贵金属检测行业的标准制定奠定了数据理论支撑。

关键词：电感耦合等离子体原子发射光谱法尾气净化用金属载体催化剂铂钯铑测定

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论综合实践活动课程开发的自然维度

教育发展研究 2007年第12B期27卷 18-24页

作者：张华安桂清华东师范大学课程与教学研究所上海200062

综合实践活动课程是基于现实世界视野对生活的探究与体验,自然世界本身成为课程。超越对自然的役用与膜拜,走向对自然的理解、欣赏与看护,是综合实践活动自然维度开发的基本原则。"在自然中"的自然探究、"关于自然"的自然探究和"为了自... 详细信息

综合实践活动课程是基于现实世界视野对生活的探究与体验,自然世界本身成为课程。超越对自然的役用与膜拜,走向对自然的理解、欣赏与看护,是综合实践活动自然维度开发的基本原则。"在自然中"的自然探究、"关于自然"的自然探究和"为了自然"的自然探究是综合实践活动自然维度开发的基本内容。此外,在开发的过程中尚须注意季节的变化、在自然探究中渗透人文精神并引导学生慎重对待探究结论。

关键词：综合实践活动课程自然维度自然探究生态伦理

GPU-based composite subdivision

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Computer Aided Drafting,Design and Manufacturing 2012年第3期22卷 50-60页

作者： LI guiqing zhang ,liahua LIANG Cheng YIN Mengxiao XIONG Yunhui School of Computer Science & Engineering South China University Guangzhou 510006 China Department of Computer Science The Hong Kong Polytechnic University Hong Kong China VCC Shenzhen Institute of Advanced Technology Shenzhen 518055 China

This paper proposes a novel strategy based on fragment meshes of Shiue et al. for GPU rendering of compos- ite subdivision surfaces. Two enumeration systems are established to label the primitives of each fragment mesh. A sector-layer-index enumeration system is responsible for retrieving proximities for subdivision masks while a sec- tor-index enumeration system designates a 2D texture buffer in GPU. Recurring to the free conversion between them, our approach may get rid of lookup tables that are designed to record subdivision masks. In addition, relatively small composite subdivision masks make it easy to develop automatically retrieving techniques. Finally, as center vertices are often irregular, their computation is related to an average with alterable number of items. Considering that variable loop is not efficient in GPU, we evaluate the center vertex of each fragment mesh using the linear combination of its level 0, level 1 and limit positions instead of averaging schemes. Experiments demonstrate that our approach generally outper- forms that of Shiue et al. in FPS by a long way.

关键词： subdivision surfaces GPU rendering composite subdivision index system

湘中矿集区钨与锑-金成因联系探讨:来自曹家坝钨矿床和龙山锑金矿床Sr-Nd-H-O同位素的制约

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岩石学报 2023年第6期39卷 1847-1860页

作者：张志远谢桂青袁亮河北地质大学河北省战略性关键矿产资源重点实验室石家庄050031 中国地质大学地球科学与资源学院北京100083 自然资源部战略性金属矿产找矿理论与技术重点实验室北京100083 湖南新龙矿业有限责任公司邵阳422927

湘中是全球最大的锑金矿集区,近年来又陆续探明了一批钨矿床,但这些钨矿和锑金矿之间的关系目前尚不明确。曹家坝钨矿床是目前该矿集区内规模最大的钨矿床(19.03Mt@0.37%WO3),矿体与矽卡岩密切共生,成矿作用划分为矽卡岩阶段、退化蚀变... 详细信息

湘中是全球最大的锑金矿集区,近年来又陆续探明了一批钨矿床,但这些钨矿和锑金矿之间的关系目前尚不明确。曹家坝钨矿床是目前该矿集区内规模最大的钨矿床(19.03Mt@0.37%WO3),矿体与矽卡岩密切共生,成矿作用划分为矽卡岩阶段、退化蚀变阶段和石英-白钨矿-硫化物阶段。不同阶段白钨矿δ18OV-SMOW变化范围为6.0‰-7.9‰,δDV-SMOW变化范围为-79.1‰--68.9‰,对应的δ18OH2O变化范围为3.3‰-5.2‰。白钨矿(87Sr/86Sr)t变化范围为0.72215-0.73049,εNd(t)变化范围为-12.8--10.6。龙山锑金矿床是矿集区内发育的大型脉状锑金矿床(4.2Mt@3.4%Sb和3.7g/t Au),矿体赋存在震旦系江口组板岩中,发育两个世代的白钨矿与辉锑矿共生。白钨矿δ18OV-SMOW变化范围为5.4‰-9.0‰,δDV-SMOW变化范围为-72.9‰--60.2‰,对应的δ18OH2O变化范围为3.1‰-6.7‰。Sr-Nd-H-O多元同位素特征显示,曹家坝钨矿床的成矿物质和成矿流体以岩浆来源为主,龙山锑金矿床有岩浆流体参与成矿,两者均有少量板溪群基底地层和大气降水的加入。综合本次及前人研究成果,曹家坝钨矿床和龙山锑金矿床具有成因联系,二者均是湘中矿集区晚三叠世岩浆热液W-Sb-Au成矿系统的重要组成部分。

关键词：白钨矿 Sr-Nd-H-O同位素曹家坝钨矿床龙山锑金矿床湘中矿集区