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Brain-derived neurotrophic factor inhibits glucose intolerance after cerebral ischemia

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Neural Regeneration Research 2013年第25期8卷 2370-2378页

作者： Xiaoliang Shu Yongsheng zhang Han Xu Kai Kang donglian Cai Department of Nutrition Affiliated Dongfang Hospital of Tongji University Department of Nutrition First Affiliated Hospital of Guangxi Medical University Department of Nutrition Affiliated Changhai Hospital of the Second Military Medical University of Chinese PLA

Brain-derived neurotrophic factor is associated with the insulin signaling pathway and glucose me- tabolism. We hypothesized that expression of brain-derived neurotrophic factor and its receptor may be involved in glucose intolerance following ischemic stress. To verify this hypothesis, this study aimed to observe the changes in brain-derived neurotrophic factor and tyrosine kinase B receptor expression in glucose metabolism-associated regions following cerebral ischemic stress in mice. At day 1 after middle cerebral artery occlusion, the expression levels of brain-derived neurotrophic factor were significantly decreased in the ischemic cortex, hypothalamus, liver, skeletal muscle, and pancreas. The expression levels of tyrosine kinase B receptor were decreased in the hypothalamus and liver, and increased in the skeletal muscle and pancreas, but remained unchanged in the cortex Intrahypothalamic administration of brain-derived neurotrophic factor （40 ng） suppressed the de- crease in insulin receptor and tyrosine-phosphorylated insulin receptor expression in the liver and skeletal muscle, and inhibited the overexpression of gluconeogenesis-associated phosphoenolpy- ruvate carboxykinase and glucose-6-phosphatase in the liver of cerebral ischemic mice. However, serum insulin levels remained unchanged. Our experimental findings indicate that brain-derived neurotrophic factor can promote glucose metabolism, reduce gluconeogenesis, and decrease blood glucose levels after cerebral ischemic stress. The low expression of brain-derived neurotrophic factor following cerebral ischemia may be involved in the development of glucose intolerance.

关键词： neural regeneration brain injury cerebral ischemic stress brain-derived neurotrophic factor insulinreceptor cerebral ischemia/reperfusion injury hypothalamus diabetes mellitus hyperglycemia glucose intolerance grants-supported paper neuroregeneration

基于UWB技术的斗轮机定位在数字化煤场应用研究

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电力科技与环保 2019年第4期35卷 60-62页

作者：张冬练李伟李春艳李茂荣黄宝霞成佳慧国电南京煤炭质量监督检验中心江苏南京210031 南京国电环保科技有限公司江苏南京210061 不详

国内燃煤火力发电厂来煤情况复杂,锅炉基本上是用优、劣煤混配以达到降低火力发电成本。少数电厂建成的数字化煤场管理系统已实现了煤场分区管理、煤场出入库管理、煤场盘点管理、煤场三维图形展示,配煤掺烧等功能。斗轮机是输煤系统中... 详细信息

国内燃煤火力发电厂来煤情况复杂,锅炉基本上是用优、劣煤混配以达到降低火力发电成本。少数电厂建成的数字化煤场管理系统已实现了煤场分区管理、煤场出入库管理、煤场盘点管理、煤场三维图形展示,配煤掺烧等功能。斗轮机是输煤系统中取煤和堆煤的重要设备之一,斗轮机定位准确性、斗轮机管控程序是数字化煤场管理系统的关键环节。实际应用过程中由于斗轮机定位精度差、斗轮机管控程序落后,影响了数字化煤场管理系统使用效果,而UWB系统采用TOA或TDOA算法,精确的确定一个定位标签的位置。针对上述问题,提出将UWB技术应用于斗轮机定位,开发堆取料指导系统,提高堆煤、取煤精度。

关键词： UWB定位技术斗轮机数字化煤场管理系统堆取料指导系统

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六盘水蟠龙镇古茶树试制不同茶类的品质分析

贵州农业科学 2021年第8期49卷 135-142页

作者：张冬莲刘彦吕金丽赵明汪志威肖钧吴迪六盘水市农业科学研究院贵州六盘水553000 云南农业大学龙润普洱茶学院云南昆明650201

【目的】古茶树资源具有抗旱、抗寒、抗病虫害等各种优质基因,是开发茶叶新产品、丰富茶产品结构的宝库。探明六盘水蟠龙镇古茶树资源鲜叶品质成分及不同工艺对六盘水蟠龙镇古茶树制成茶品质的影响,为开展地方特色茶树新品种的选育及品... 详细信息

【目的】古茶树资源具有抗旱、抗寒、抗病虫害等各种优质基因,是开发茶叶新产品、丰富茶产品结构的宝库。探明六盘水蟠龙镇古茶树资源鲜叶品质成分及不同工艺对六盘水蟠龙镇古茶树制成茶品质的影响,为开展地方特色茶树新品种的选育及品种改良提供参考。【方法】以六盘水蟠龙镇古茶树鲜叶为原料,采用绿茶工艺、红茶工艺、红茶创新工艺、绿茶创新工艺共4种不同加工工艺试制茶叶,分析比较其水浸出物、茶多酚、咖啡碱、氨基酸、可溶性总糖、酚氨比及儿茶素等生化品质成分和外形、汤色、香气、滋味、叶底等感官品质。【结果】蟠龙镇古茶树茶青水浸出物含量44.17%~53.58%,茶多酚含量28.45%~34.98%,咖啡碱含量2.43%~3.36%,氨基酸总量2.19%~5.35%,可溶性总糖在4.50%~6.58%,酚氨比6.54~14.64。各主要品质成分大致呈绿茶工艺>绿茶创新工艺>红茶工艺、红茶创新工艺的趋势,感官审评得分呈绿茶工艺>绿茶创新工艺>红茶工艺>红茶创新工艺。绿茶工艺制作的茶样感官品质最佳,较协调地保留了生化品质成分;绿茶创新工艺制作的茶样茶香气最好,且各品质感官审评得分和生化品质成分含量仅次于绿茶工艺。【结论】蟠龙镇古茶树主要适制绿茶,初步确定绿茶工艺为古茶树的最佳加工工艺;绿茶创新工艺也适合蟠龙镇古茶树的加工。

关键词：古茶树试制感官品质生化品质六盘水

Unambiguously Resolving the Potential Neutrino Magnetic Moment Signal at Large Liquid Scintillator Detectors

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Chinese Physics Letters 2021年第11期38卷 18-22页

作者： Ziping Ye Feiyang zhang donglian Xu Jianglai Liu Tsung-Dao Lee Institute Shanghai 200240China INPAC and School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China Shanghai Laboratory for Particle Physics and Cosmology Key Laboratory for Particle Physics and Cosmology(MOE)Shanghai 200240China

Non-vanishing electromagnetic properties of neutrinos have been predicted by many theories beyond the Standard Model, and an enhanced neutrino magnetic moment can have profound implications for fundamental physics. The XENON1T experiment recently detected an excess of electron recoil events in the 1–7 keV energy range, which can be compatible with solar neutrino magnetic moment interaction at a most probable value of μ_(v) = 2.1 × 10^(-11)μ_(B).However, tritium backgrounds or solar axion interaction in this energy window are equally plausible *** multi-tonne noble liquid detectors will test these scenarios more in depth, but will continue to face similar ambiguity. We report a unique capability of future large liquid scintillator detectors to help resolve the potential neutrino magnetic moment scenario. With O(100) kton·year exposure of liquid scintillator to solar neutrinos, a sensitivity of μ_(v) < 10^(-11)μ_(B) can be reached at an energy threshold greater than 40 keV, where no tritium or solar axion events but only neutrino magnetic moment signal is still present.

关键词： Unambiguously Resolving the Potential Neutrino Magnetic Moment Signal at Large Liquid Scintillator Detectors

Tube Model Predictive Control Based Cyber-attack-resilient Optimal Voltage Control Strategy in Wind Farms

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CSEE Journal of Power and Energy Systems 2024年第2期10卷 530-538页

作者： Zhenming Li Minghao Wang Yunfeng Yan donglian Qi Zhao Xu Jianliang zhang Zezhou Wang College of Electrical Electronic Engineering Zhejiang UniversityHangzhou 310058China Department of Electrical Engineering The Hong Kong Polytechnic UniversityKowloonHong KongChina Haiyan power supply company of State Grid Zhejiang Electric Power Co. LtdHangzhouChina

Optimal voltage controls have been widely applied in wind farms to maintain voltage stability of power *** order to achieve optimal voltage operation,authentic grid information is widely needed in the sensing and actuating ***,this may induce system vulnerable to malicious *** this end,a tube model predictive control-based cyber-attack-resilient optimal voltage control method is proposed to achieve voltage stability against malicious *** proposed method consists of two cascaded model predictive controllers(MPC),which outperform other peer control methods in effective alleviation of adverse effects from cyber-attacks on actuators and sensors of the ***,efficiency of the proposed method is evaluated in sensor and actuator cyber-attack cases based on a modified IEEE 14 buses system and IEEE 118 buses *** Terms-Attack-resilient control,optimal voltage control,tube-based model predictive control,wind farm-connected power system.

关键词： Attack-resilient control optimal voltage control tube-based model predictive control wind farm-connected power system

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火电厂智慧煤场管控系统技术研究

电力科技与环保 2020年第5期36卷 49-53页

作者：张冬练成佳慧沈纳昊柯文明王良东黄宝霞国电南京煤炭质量监督检验有限公司江苏南京210031 南京国电环保科技有限公司江苏南京210061 华北电力大学(保定) 河北保定071003

当前国内对能源需求放缓,电力产能过剩的矛盾依然存在,为有效应对复杂的电力和煤炭市场形势,本文阐述了目前火力发电厂在煤场管理存在燃煤混乱堆放、煤场设备自动化程度低、信息融合困难等诸多问题,提出建设智慧煤场管控系统,实现煤场... 详细信息

当前国内对能源需求放缓,电力产能过剩的矛盾依然存在,为有效应对复杂的电力和煤炭市场形势,本文阐述了目前火力发电厂在煤场管理存在燃煤混乱堆放、煤场设备自动化程度低、信息融合困难等诸多问题,提出建设智慧煤场管控系统,实现煤场三维建模、堆取料机自动作业、煤场信息化管理、科学配煤掺烧,深入挖掘内部潜力,提升燃料控价能力,降低发电成本,增强盈利能力。

关键词：煤场三维建模堆取料机自动作业煤场管理信息系统智慧煤场管控

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增效作用对胶磷矿浮选行为的影响

武汉化工学院学报 1998年第4期20卷 33-36页

作者：谢恒星李冬莲张傲时彭儒

探讨了几种表面活性剂对脂肪酸类捕收剂Ｗ０３的增效作用及其对胶磷矿浮选行为的影响．结果表明，阴离子型表面活性剂十二烷基苯磺酸钠（ＳＤＢＳ）对Ｗ０３具有良好的增效作用，能明显改善胶磷矿的浮选特性．当矿浆温度为２５～４０℃... 详细信息

探讨了几种表面活性剂对脂肪酸类捕收剂Ｗ０３的增效作用及其对胶磷矿浮选行为的影响．结果表明，阴离子型表面活性剂十二烷基苯磺酸钠（ＳＤＢＳ）对Ｗ０３具有良好的增效作用，能明显改善胶磷矿的浮选特性．当矿浆温度为２５～４０℃时，混合使用Ｗ０３和ＳＤＢＳ，粗选精矿品位和回收率比单独使用Ｗ０３时分别提高１％和１％～４％．

关键词：增效作用表面活性剂磷块岩浮选捕集剂

Distributed Event-triggered Control for Frequency Restoration in Islanded Microgrids with Reduced Trigger Condition Checking

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CSEE Journal of Power and Energy Systems 2024年第5期10卷 2156-2165页

作者： Yulin Chen donglian Qi Zhenming Li Zhenyu Wang Xinyi Yang Jianliang zhang College of Electrical Engineering Zhejiang UniversityHangzhou 310027China

For islanded microgrids(MGs),distributed control is regarded as a preferred alternative to centralized control for the frequency restoration of ***,distributed control with successive communication restricts the efficiency and resilience of the control *** address this issue,this paper proposes a distributed event-triggered control strategy for the frequency secondary control in islanded *** proposed event-triggered control is Zeno behavior free and enables each DG to update and propagate its state to neighboring DGs only when a specific“event”occurs,which significantly reduces the communication *** with the existing event-triggered control,a trigger condition checking period of the proposed event-triggered control is provided to reduce the computation burden when checking the trigger ***,using the aperiodicity and intermittent properties of the communication,a simple detection principle is proposed to detect and isolate the compromised communication links in a timely and economic fashion,which improves the resilience of the system against FDI ***,the control effectiveness of the proposed control scheme is validated by the simulation results of the tests on an MG with 4 DGs.

关键词： Distributed control event-triggered control islanded microgrid secondary control

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贵州密苗型生姜农艺性状与产量的相关性分析

贵州农业科学 2020年第5期48卷 41-46页

作者：罗凯吕金丽吴迪莫庆忠张冬莲吕树鸣王永恒六盘水市农业科学研究院贵州六盘水553000 贵州大学农学院贵州贵阳550025 盘州市农业农村局贵州六盘水553500

为贵州密苗型生姜的选育及选种留种提供参考,以8份密苗型生姜资源为材料,利用相关性分析、通径分析、主成分分析、套索回归分析等方法,进行生姜农艺性状与产量的多重分析。结果表明:8份密苗型生姜农艺性状的变异系数为7.378%~40.225%,... 详细信息

为贵州密苗型生姜的选育及选种留种提供参考,以8份密苗型生姜资源为材料,利用相关性分析、通径分析、主成分分析、套索回归分析等方法,进行生姜农艺性状与产量的多重分析。结果表明:8份密苗型生姜农艺性状的变异系数为7.378%~40.225%,且株高、株幅、分枝数、根状茎宽与单株产量呈极显著相关,其相关系数分别为0.534、0.707、0.746和-0.456;株高、株幅、分枝数、地上茎高和主茎叶面积为生姜高产形态因子,子姜节数为低产形态因子;生姜产量主要决定因子为分枝数、主茎叶面积、主茎粗、子姜粗和主茎叶片数,高产型生姜的主要特征为较多的分枝数、发达的主茎同化系统及粗壮的子姜。

关键词：生姜密苗型农艺性状产量决定因子